Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT05439226Recruiting
Diet plan targeting liver fat for type 2 diabetes
This study tests whether a Chinese medical nutrition therapy diet can reduce liver fat and help manage type 2 diabetes in people who also have fatty liver. You may be asked to follow a specific eating plan and keep your diabetes care stable during the study.
Yichang, HubeiAges 18–75 - NCT05714917Recruiting
Studying recovery after nerve damage from NOS use
This study looks at how neurological symptoms (like numbness, weakness, unsteadiness, or walking problems) recover after damage caused by NOS use. It may help researchers understand what recovery looks like and what support or treatments could work best.
BirminghamAges 16–40 - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT05286892Recruiting
Diabetes education for people returning home from prison
This study offers diabetes learning through virtual (online) sessions for adults with diabetes who are transitioning back to community living after prison. It aims to help you better manage diabetes during reentry and improve day-to-day health.
Storrs, ConnecticutAges 18 years+ - NCT06770660Recruiting
Remote exercise for teen fitness
This trial tests whether exercising at home through video calls can improve heart and lung fitness in teenagers aged 12 to 17. It might be a convenient way to stay active if you cannot get to a gym or sports club.
SingaporeAges 12–18 - NCT06765057RecruitingPhase 2/Phase 3
Probiotics for Depression and Metabolic Health
This trial tests whether taking a probiotic supplement can improve both depression symptoms and metabolic health (like waist size, blood sugar, and cholesterol) in people with major depression. It may be a good fit if you are already on an antidepressant and have signs of metabolic syndrome.
Riyadh, Riyadh RegionAges 18–65 - NCT06763549Enrolling by invitation
AI-powered wearable patch for heart and lung monitoring
This study tests an AI-powered wearable patch (the COR ECG) to see if it can better track heart and lung health. It may help doctors find problems earlier without needing bulky equipment.
Melbourne, FloridaAges 18 years+ - NCT06760819RecruitingPhase 2
Sevacertinib for solid tumors with HER2 mutations
This study tests an oral tablet called sevacertinib in people with solid tumors (not lung cancer) that have a HER2 mutation. It aims to see how well the drug works and how safe it is for people who have tried other treatments or have no good options left.
Birmingham, AlabamaAges 18 years+ - NCT06769152RecruitingPhase 2
HLX43 for advanced gynecological cancers
This trial tests a new drug, HLX43, that targets a protein called PD-L1 found on some cancer cells. It is for people with advanced cervical or ovarian cancer that has stopped responding to standard treatments.
Ji'nan, ShandongAges 18–75 - NCT06760546RecruitingPhase 3
Testing setmelanotide for weight gain after brain injury
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Birmingham, AlabamaAges 4 years+ - NCT06767813RecruitingPhase 2
Study of TQB2868, anlotinib, and chemo for first-line pancreatic cancer
This trial tests a new combination of drugs (TQB2868, anlotinib, and chemotherapy) as a first treatment for metastatic pancreatic cancer that has spread. It may help if you have not had prior treatment for advanced disease.
Zhengzhou, HenanAges 18–75 - NCT06768489RecruitingPhase 1
Combination therapy for multiple myeloma and related conditions
This trial tests a new drug combined with other medicines for people with multiple myeloma, a related condition called AL amyloidosis, or high-risk smoldering multiple myeloma. It aims to see if the combination is safe and effective.
Denver, ColoradoAges 18 years+ - NCT06764719Recruiting
Hair follicles for cell therapy
This trial tests if special hair follicles can be used for cell replacement therapy in disease. It may help people with certain medical conditions.
Toronto, QuebecAges 18–80 - NCT06762730RecruitingPhase 4
Zoledronic acid to prevent bone loss from HIV treatment
This trial tests if zoledronic acid, a drug that strengthens bones, can prevent bone loss caused by starting HIV treatment. It is for people newly diagnosed with HIV who have not yet taken any HIV medication.
HaifaAges 18 years+ - NCT06764082Recruiting
Nutrition study for babies with biliary atresia
This study tests whether a special nutrition plan helps babies with biliary atresia recover better after Kasai surgery. It is for infants under 3 months old who are ready for surgery.
Wuhan, HubeiAges 1 day–3 months - NCT06760507Recruiting
Family history screening for BRCA cancers in rural clinics
This trial tests a program to help women in rural public health clinics learn about their family history of BRCA-related cancers. It aims to increase genetic screening and counseling for those at higher risk.
Atlanta, GeorgiaAges 25 years+ - NCT06768827Recruiting
Obesity mechanisms study for teens
This study looks at how bodies process food to understand obesity in teenagers. It may help find new ways to prevent or treat obesity.
New Haven, ConnecticutAges 15–22 - NCT06770673Recruiting
Together Overcoming Diabetes - Great Plains
This study tests a program to help American Indian/Alaska Native adults with type 2 diabetes and a young family member (10-25 years old) work together to improve diabetes management. You and a youth in your home would join as a team and be assigned to one of two support programs.
Rapid City, South DakotaAges 10 years+ - NCT06770452RecruitingPhase 2
HRS-4642 combo for first-line advanced pancreatic cancer
This trial tests a new targeted drug (HRS-4642) combined with nimotuzumab and chemotherapy for people with advanced pancreatic cancer that has a specific gene change called KRAS G12D. It's for those who haven't had treatment for advanced disease yet.
Hangzhou, ZhejiangAges 18–75 - NCT06767150RecruitingPhase 4
Bone treatment after stopping denosumab for osteoporosis
This trial tests whether giving zoledronic acid (a bone-strengthening infusion) right after stopping denosumab can help prevent bone loss in women with post-menopausal osteoporosis. It may be a good option if you have finished at least 2 years of denosumab and your doctor says it's safe to stop.
AmiensAges 18 years+ - NCT06768216Recruiting
Mediterranean vs. low-fat diet for fatty liver in overweight kids
This trial compares two diets—a Mediterranean-style diet and a low-fat diet—to see which better reduces liver fat in overweight children and teens with fatty liver disease (MASLD). It aims to find a safe, effective eating plan for young people.
New Delhi, National Capital Territory of DelhiAges 8–18 - NCT06770049Recruiting
Personalized lifestyle program for weight loss in obesity
This study tests a lifestyle program tailored to your biology or behavior to help with weight loss. It is for adults with obesity who haven't had weight loss surgery or used certain weight loss medications recently.
Rochester, MinnesotaAges 18–65 - NCT06765707Enrolling by invitation
Monitoring symptoms to improve medication use in breast cancer
This trial tests if tracking how you feel and reporting your symptoms can help women with hormone receptor-positive breast cancer take their hormone-blocking medication more consistently. It may be a good fit if you have been prescribed aromatase inhibitors or similar therapy and have had trouble taking it as directed.
Chicago, IllinoisAges 18 years+ - NCT06768437Recruiting
Heart fat and preserved ejection fraction heart failure trial
This study looks at whether fat around the heart affects a type of heart failure where the heart pumps well but is stiff (HFpEF). You may be able to join if you have this condition, are 18 or older, and can understand English.
Leicester, LeicestershireAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.