Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06636058Recruiting
Digital treatment for weight and mood in adults 50+
This study tests a digital program that helps with weight loss and depression at the same time. It is designed for Black, Hispanic, and other adults over 50 who carry extra weight and feel down.
Chicago, IllinoisAges 50–74 - NCT06640179Recruiting
Lifestyle program for kidney transplant recipients
This study tests a diet and exercise program for people who recently received a kidney transplant. It aims to see if the program is safe and helpful for improving health after transplant.
Kansas City, KansasAges 18 years+ - NCT06643780RecruitingPhase 4
Denosumab for muscle loss in older adults with osteoporosis
This study tests whether a drug called Denosumab, which is used to treat bone loss, can also help improve muscle strength and mass in older adults who have both osteoporosis and sarcopenia. If you qualify, you would receive the drug and be monitored over time to see if it helps your bones and muscles.
Hong KongAges 65 years+ - NCT06633575Recruiting
Exercise study for prediabetes in Han Chinese adults
This study looks at how an exercise program can improve prediabetes (a condition where blood sugar is higher than normal but not yet diabetes) in adults of Han Chinese descent. It aims to find the best types of exercise to help control blood sugar and prevent diabetes.
Shanghai, Shanghai MunicipalityAges 19–55 - NCT06637137Recruiting
Blood management for cardiac surgery patients
This trial studies a program to manage blood levels before, during, and after heart surgery. It may help reduce the need for blood transfusions and improve recovery.
RomaAges 18 years+ - NCT05113368RecruitingPhase 2
Regorafenib plus fulvestrant for recurrent low-grade ovarian cancer
This trial tests whether regorafenib (a targeted pill) plus fulvestrant (an injection that lowers estrogen signaling) can slow down recurrent low-grade serous ovarian cancer. It may help people whose cancer has returned after prior treatments.
Cleveland, OhioAges 18 years+ - NCT06508307RecruitingPhase 1
A study of an injected virus for advanced solid tumors
This trial tests a new treatment where a virus (GC001) is injected directly into a tumor. The virus is designed to attack cancer cells and may help people with advanced solid tumors that haven't responded to other treatments.
Zhengzhou, HenanAges 18–75 - NCT06619041Recruiting
HealthyTogether: Weight Management with a Partner
This study tests a weight management program where you and a partner (like a spouse or friend) work together virtually. It aims to help you lose weight and improve health habits alongside someone you trust.
Aurora, ColoradoAges 18 years+ - NCT06627569Recruiting
Exercise for stress-related eating in veterans
This study tests whether exercise can change how the brain responds to stress-related eating in veterans. It may help reduce stress-driven eating and improve overall health.
Aurora, ColoradoAges 18–75 - NCT06291766Recruiting
Gestational diabetes after gastric bypass study
This study looks at how a continuous glucose monitor (CGM) can help manage blood sugar in pregnant women who have had gastric bypass surgery and now have gestational diabetes. It aims to find better ways to monitor and treat diabetes during pregnancy for women after this type of weight-loss surgery.
LundAges 18–50 - NCT06628271Recruiting
Breath-holding Spells Study for Young Children
This study looks at a common condition in young children called breath-holding spells. It aims to better understand how to manage these episodes, which can be scary but are usually harmless.
EslövAges birth–5 years - NCT06627504Recruiting
Sleep study for teens with type 1 diabetes
This study tests whether getting more sleep helps improve metabolic health in teens with type 1 diabetes who are not getting enough sleep. If you are between 14 and 19, use an insulin pump, and typically sleep 7 hours or less on school nights, you may be eligible.
Aurora, ColoradoAges 14–19 - NCT06625762Recruiting
Nantes bariatric surgery study
This study follows people who are preparing for bariatric (weight-loss) surgery to see how the surgery affects their health over time. It is being done to better understand the benefits and risks of bariatric surgery.
Nantes, Loire-AtlantiqueAges 18–70 - NCT06627309Recruiting
Rapid blood protein response and remission in AL amyloidosis
This trial is for people with AL amyloidosis who are being treated with daratumumab, bortezomib, and dexamethasone. It looks at how quickly a certain blood protein (called dFLC) drops after treatment starts and whether that predicts a complete remission.
Beijing, Beijing MunicipalityAges 18–99 - NCT06627868Recruiting
NAD+ metabolism in human brown fat
This study explores how the body's natural substance NAD+ works in brown fat, a type of fat that burns calories. It may help researchers understand metabolism and find new ways to treat obesity.
TurkuAges 30–65 - NCT06624046Recruiting
Sleep and glucose study for type 1 diabetes
This study looks at how sleep affects blood sugar and heart health in people with type 1 diabetes. If you have irregular sleep and want to improve it, researchers will test a wearable device and sleep coaching.
Chicago, IllinoisAges 18–50 - NCT06617923RecruitingPhase 2
Senaparib and Temozolomide for ARID1A-Mutated Ovarian Cancer
This trial tests a combination of two drugs, senaparib and temozolomide, for women with a specific type of ovarian cancer that has come back or is resistant to platinum-based chemotherapy. It is for patients whose tumor has a change in the ARID1A gene.
Baltimore, MarylandAges 18 years+ - NCT06622603RecruitingPhase 4
Testing lower doses of febuxostat in well-controlled gout
This trial tests if gradually lowering the dose of the gout medication febuxostat is safe for people whose gout has been well-controlled for at least 5 years. The goal is to see if a lower dose can still keep uric acid levels in a healthy range.
Seongnam-si, Gyeonggi-doAges 19–79 - NCT06623032Recruiting
Medium-chain fatty acids in MCADD patients and healthy volunteers
This trial tests how medium-chain fatty acids (a type of fat found in coconut oil) affect metabolism in people with MCADD, a genetic condition that affects fat breakdown, compared to healthy people. The results may help guide dietary advice for those with MCADD.
CopenhagenAges 18–80 - NCT06627543Enrolling by invitation
Enzyme replacement therapy for heart health in Gaucher type 3
This study looks at how enzyme replacement therapy affects heart function in children with Gaucher disease type 3. It aims to see if the therapy helps keep the heart healthy.
AsyutAges Any age - NCT06630182Recruiting
Does personality affect diabetic foot wound healing?
This study looks at how your feelings and personality might affect the healing of a diabetic foot wound. Researchers will ask you to complete questionnaires about your emotional state to see if there is a link to wound recovery.
DijonAges 18–18 - NCT06629272Recruiting
Reducing Unnecessary Thyroid Hormone in Older Adults
This study is testing whether it’s safe to slowly reduce or stop thyroid hormone medication in older adults who may not need it. The goal is to improve health and avoid unnecessary treatment.
San Francisco, CaliforniaAges 65 years+ - NCT06630585RecruitingPhase 3
Tirzepatide added to insulin pump for type 1 diabetes
This study tests whether adding a weekly injection of tirzepatide (a drug that helps with blood sugar and weight) can improve glucose control in adults with type 1 diabetes who already use an automated insulin pump. It may help you if your blood sugar is not at target despite using a pump.
Chêne-Bougeries, Canton of GenevaAges 18–65 - NCT06624462Recruiting
Meta Care Clinic for weight and health in severe mental illness
This study tests a special clinic that helps people with schizophrenia or bipolar disorder manage their weight and metabolic health while taking antipsychotic medication. It focuses on improving overall health with practical support.
Glostrup Municipality, Capital RegionAges 18–45
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.