Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06111040Recruiting
Parenting study for food-driven young children
This study tests a program to help parents handle feeding their 4- or 5-year-old child who is very motivated by food. It aims to support healthy eating habits.
Philadelphia, PennsylvaniaAges 4–5 - NCT06105957Recruiting
Digital weight loss program for rural adults
This study tests a digital weight loss program designed for adults living in rural areas. It uses a smartphone app, website, and video group sessions to help you lose weight through diet and physical activity.
Columbia, South CarolinaAges 18 years+ - NCT06104969Recruiting
Biomarkers for active diabetic foot ulcers
This study is looking for people with diabetes who have an open foot or ankle ulcer. Researchers want to collect samples to find biomarkers, which are natural signs in the body that could help improve treatment and healing. It may be a good fit if you have a diabetic foot ulcer and are not currently in another drug trial for ulcers.
Tucson, ArizonaAges 18 years+ - NCT06124586Recruiting
Early angioplasty for diabetic foot ulcers
This trial tests if an early procedure to open blocked leg arteries (angioplasty) helps heal foot ulcers in people with type 2 diabetes. It aims to improve blood flow and prevent amputation.
DüsseldorfAges 18 years+ - NCT06127446Recruiting
Genetic Changes in Ovarian Cancer in Taiwan
This trial is creating a detailed registry of genetic changes found in ovarian tumors in Taiwan. It aims to better understand the disease by collecting tumor tissue and blood samples from patients with high-grade serous or clear cell ovarian, fallopian tube, or peritoneal cancer.
Kaohsiung CityAges 18 years+ - NCT06128980RecruitingPhase 2/Phase 3
Stopping heart meds after recovery from fast heartbeat damage
This trial tests if patients whose heart function returned to normal after treating a fast heartbeat can safely stop their heart failure medications. It aims to see if treatment can be withdrawn without the heart problems coming back.
CopenhagenAges 18 years+ - NCT06105164Recruiting
Brain's Fullness Circuit Study
This study uses brain imaging and mild magnetic stimulation to explore how a brain circuit helps you feel full after eating. It may help us understand eating behaviors and weight regulation.
Belmont, MassachusettsAges 18–65 - NCT06129110Recruiting
Weight loss and muscle fat study for adults aged 18-70
This study looks at how losing weight affects the fat that sits inside your muscles (called intermuscular fat). It might help people with overweight to better understand how weight loss can improve muscle health.
Aurora, ColoradoAges 18–70 - NCT05906472Recruiting
Feeding through a tube after tracheostomy in the ICU
This study tests a specific way of continuing tube feeding for people who need a tracheostomy after being on a breathing tube in the ICU. The goal is to see if this feeding approach is safe and beneficial for recovery.
Danbury, ConnecticutAges 18 years+ - NCT02602769Recruiting
Testing blood traits in children with ROHHAD syndrome
This trial studies children with ROHHAD syndrome to better understand their body chemistry and other blood features. The results may help researchers learn what drives the condition and how it might be tracked over time.
Boston, New YorkAges 2–20 - NCT01998750Recruiting
Study of genes in severe early childhood obesity
This study looks for genetic (inherited) reasons for severe obesity that starts in very early childhood. It may help doctors better understand the cause of your child’s weight gain and guide future treatment.
Boston, MassachusettsAges Up to 80 years - NCT03047369Recruiting
Myelin brain disorder research biobank for samples and data
This study collects brain-related medical information and biological samples to help researchers better understand leukodystrophies and other white-matter brain disorders. It may help future diagnosis and treatments by building a valuable “biobank” of patient data and samples.
Los Angeles, CaliforniaAges Any age - NCT03364803Recruiting
Sharing treatment results for people with Cushing’s syndrome
This is a study that collects and reviews information about how people with Cushing’s syndrome (including some mild forms and certain “silent” tumors) are diagnosed and treated, and what outcomes they have. It may help researchers understand which treatments work best in different types of the condition.
Basking Ridge, New JerseyAges 14 years+ - NCT06092346Recruiting
Understanding rare purine and pyrimidine metabolism disorders
This study aims to learn more about rare disorders of purine and pyrimidine metabolism (DPPM), which can affect the brain, immune system, kidneys, and muscles. Researchers will study people with these disorders, their family members, and healthy volunteers to better understand the condition over time.
Bethesda, MarylandAges 1 month–100 years - NCT06103487Enrolling by invitation
Long-term follow-up for RGX-111 treatment
This study follows participants who previously received the RGX-111 treatment to monitor their health over time. It helps researchers understand the long-term effects and safety of the therapy.
Orange, CaliforniaAges Any age - NCT06092034RecruitingPhase 2
Gene therapy for Danon disease in males
This trial tests a gene therapy called RP-A501 for males with Danon disease, a genetic condition that affects the heart. The treatment aims to fix the faulty gene to help improve heart function and slow disease progression.
La Jolla, CaliforniaAges 8 years+ - NCT06081439Recruiting
Immune markers and mental fatigue in Graves' disease
This study looks at whether certain immune system markers are linked to mental fatigue (feeling tired or foggy in the mind) in people with newly diagnosed Graves' disease. If you join, you'll help researchers understand how your immune system might affect your energy and thinking.
GothenburgAges 18–72 - NCT04885179Recruiting
Study of SPLIS genetics and patient experiences
This observational study and patient registry collects information from people diagnosed with SPLIS due to specific changes in the SGPL1 gene, including children and newborns. It helps researchers understand the condition better and may improve future care and research planning.
San Francisco, CaliforniaAges Any age - NCT05919329RecruitingPhase 4
PSMA scan changes after starting hormone therapy for prostate cancer
This study looks at how a prostate-specific scan marker (PSMA) changes after you start or continue hormone therapy. It may help doctors better understand who responds and how quickly prostate cancer biology shifts during treatment.
Portland, OregonAges 18 years+ - NCT06099288Recruiting
Strong families start at home: A healthy eating study for Latinx families
This study tests a program to help families eat healthier together at home. It is for Latinx caregivers of young children and involves recording a few meals to see how the program helps.
Providence, Rhode IslandAges 18 years+ - NCT06094205Recruiting
BrainGate2 speech study for people with tetraplegia
This study tests a brain-computer interface to help people with severe paralysis communicate by decoding attempted speech or movements. It may offer a new way to interact with devices using only brain signals.
Sacramento, CaliforniaAges 18–80 - NCT06081348RecruitingPhase 2
Sertraline vs. placebo for anxiety in kids with developmental disorders
This trial compares sertraline (a common antidepressant) to a placebo (a pill with no medicine) to see which better reduces anxiety in children and teens who also have a neurodevelopmental disorder like autism, ADHD, or Tourette's. The goal is to help you and your child understand if this treatment might offer relief from anxiety.
Calgary, AlbertaAges 8–17 - NCT06096675Recruiting
Physical activity study for cardiac amyloidosis patients
This study tests whether a 12-week supervised exercise program is safe and helpful for people with cardiac amyloidosis and heart failure. It aims to see if regular exercise can improve how you feel and function.
Charlotte, North CarolinaAges 18 years+ - NCT06083766Recruiting
Hormone Therapy Effects on Metabolism in Transgender Adults
This study looks at how long-term gender-affirming hormone therapy affects your body's metabolism and energy use. Researchers want to understand these changes better to improve care for transgender and gender-diverse people.
Rochester, MinnesotaAges 18–40
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.