Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT05831085Recruiting
Compare procedures to improve heart blood flow in diabetes
This study compares two ways to restore blood flow to the heart—stent placement (PCI) versus bypass surgery (CABG)—in people with diabetes and significant multi-vessel coronary artery disease. It looks at outcomes using both standard heart tests and additional imaging/functional measurements to guide the best revascularization strategy.
Palo Alto, CaliforniaAges 20 years+ - NCT05835596Enrolling by invitation
App-based support to protect heart health after pregnancy
This trial tests whether a smartphone app (“MumCare”) can help improve or support cardiovascular (heart and blood vessel) health in people after certain pregnancy complications. It’s for new or recent moms who had pregnancy-related high blood pressure and/or gestational diabetes.
Oslo, OsloAges 18–50 - NCT05837767Recruiting
Radiation study for tumors that spread to soft tissue areas
This study looks at how a planned form of palliative radiation therapy treats certain solid cancers that have spread outside the brain to larger soft-tissue areas. It may help shrink tumors and relieve symptoms, but it also asks you to meet specific safety and treatment-timing rules.
Basking Ridge, New JerseyAges 18 years+ - NCT00898235Recruiting
Collecting samples and health data for amyloidosis
This study collects blood and other samples, along with health information, from people who have—or might have—amyloidosis. It aims to improve understanding of the disease and support future treatments.
Boston, MassachusettsAges 18 years+ - NCT04278651RecruitingPhase 4
Early support to treat iron-deficiency anemia in pregnancy
This trial tests whether starting treatment early in pregnancy can improve iron-deficiency anemia. You may be offered study medications and will be monitored to see if your blood counts and symptoms improve.
Philadelphia, PennsylvaniaAges 18–65 - NCT02567136Recruiting
Imaging study for people with ALS using MRI
This trial uses MRI scans to look for “imaging biomarkers” (scan patterns that may help track ALS). It may help researchers better understand disease changes over time and how ALS progresses.
Minneapolis, MinnesotaAges 21–75 - NCT03553420Recruiting
Registry for people with lipodystrophy
This is a study that keeps a medical record (a registry) of people with lipodystrophy, a condition where body fat is missing or unevenly distributed. It may help researchers understand different causes and patterns of the condition over time.
ViennaAges Any age - NCT05642819Recruiting
MRI before and after surgery for abdominal cancers
This study uses extra detailed MRI scans before and/or around planned abdominal surgery to help researchers understand changes in the body. It includes people having surgery for certain cancers and some people having surgery for non-cancer (benign) conditions.
EdinburghAges 18 years+ - NCT05799768Enrolling by invitation
Ketogenic diet for rheumatoid arthritis symptoms and inflammation
This study tests whether a very low-carbohydrate, ketogenic diet can improve rheumatoid arthritis (RA). It’s designed for people whose RA treatment is already stable and who are not currently using a keto diet or certain medicines.
Oklahoma City, OklahomaAges 18–65 - NCT05786716RecruitingPhase 2/Phase 3
Trastuzumab plus pertuzumab for HER2-mutated cancers
This trial tests whether combining trastuzumab and pertuzumab can treat cancers that have HER2 amplification or an activating HER2 mutation. It looks at people ages 12 and older, and may include both children/teens and adults, using the study drug based on their HER2 test results.
BelfastAges 12 years+ - NCT05801432Recruiting
Study of heart artery plaque in people with type 2 diabetes
This trial looks at coronary (heart) artery plaque using CT scans (CCTA) in people with type 2 diabetes who do not have symptoms. It may help doctors understand who is at risk of heart problems and how plaque changes over time.
SeoulAges 19 years+ - NCT05795439Recruiting
Plant-based nutrition program for adults with type 2 diabetes
This study tests whether a structured plant-based diet plan, weekly online classes, and keeping exercise routine steady can improve health in adults with type 2 diabetes. You may qualify if you’re able and willing to follow the program for the first 16 weeks.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05793853Recruiting
Study of how hypoparathyroidism changes over time
This study follows adults with hypoparathyroidism to better understand what symptoms and lab levels change over time. It may help doctors plan future treatments by learning the natural course of the condition, even if you already take standard medicines.
New York, New YorkAges 18–100 - NCT05806801Recruiting
Study how weight loss changes the body with or without exercise
This study looks at how your metabolism (how your body uses energy and controls blood sugar/fats) changes during weight loss, comparing weight loss alone versus weight loss plus exercise. It may help researchers understand what body changes happen with different approaches and why.
Ann Arbor, MichiganAges 18–40 - NCT05786924RecruitingPhase 1/Phase 2
Targeted cancer drug study for RAS/RAF mutation-positive tumors
This Phase 1/2 study tests S241656 (a targeted cancer medicine) in people whose cancers have certain “RAS/RAF” gene changes. It may help shrink tumors or control cancer growth, and also finds the safest dose and best way to use the drug.
Gilbert, ArizonaAges 18 years+ - NCT05798676Recruiting
Study of pregnancy factors linked to a child’s growth
This study looks at breastfeeding mothers and how a mother’s pregnancy and health factors may relate to a child’s growth and body fat. You might be able to join if you were normal weight or overweight/obese before pregnancy and you meet the pregnancy and delivery health requirements.
La Plata, Buenos AiresAges 18–40 - NCT05800509Recruiting
Program for gestational diabetes and low mood in pregnancy
This study offers an intervention program to help people who are diagnosed with gestational diabetes and may also experience depression during pregnancy. It may help improve health during pregnancy and support mood and well-being with smartphone-based participation.
TaipeiAges 20 years+ - NCT05811624Recruiting
Lifestyle program for weight and chronic low back pain
This trial studies whether a lifestyle change program (often diet and activity habits) can reduce long-lasting low back pain in overweight or obese adults. It also aims to see if people can keep their usual care while adding the lifestyle program.
BrusselsAges 18–65 - NCT05799222Recruiting
Nutrition program for obesity and diabetes risk
This trial tests a medically guided nutrition program to help improve weight and blood sugar in adults with obesity or early diabetes risk. It specifically targets people who meet income guidelines and don’t already use most diabetes or anti-obesity medicines.
Boston, MassachusettsAges 18–65 - NCT05793996RecruitingPhase 4
Testing an iron infusion for iron deficiency in HFpEF
This study checks how common iron deficiency is in people with HFpEF (heart failure with preserved pumping strength) and tests whether an iron infusion (Ferinject®) improves health. It targets people with stable heart symptoms and lab results showing low iron stores or related iron deficiency.
TomskAges 18 years+ - NCT05799846Recruiting
Online strategies to help with weight loss
This study tests a cognitive (thinking-focused) approach delivered through the internet to help you lose weight. You may be eligible if you have overweight or obesity and can regularly complete online activities and visits.
Providence, Rhode IslandAges 18–70 - NCT05807594Recruiting
Online program to help manage weight gain during pregnancy
This trial tests an at-home (online) coaching program to help pregnant people gain weight at a healthier rate. It may help you stay on track during pregnancy and understand what changes work best for you.
University Park, PennsylvaniaAges 18–45 - NCT05795582Recruiting
Measuring blood flow in people with type 2 diabetes
This study tests a simple, noninvasive technique (photoplethysmography) to measure blood flow in the legs of people with type 2 diabetes. It may help doctors better detect and monitor peripheral artery disease (PAD), a condition that narrows arteries and can lead to leg pain or poor healing.
AntibesAges 18 years+ - NCT05785780Enrolling by invitation
Help improve colon cancer screening for people with diabetes
This study looks for better ways to make sure people with diabetes get up-to-date colon cancer screening. If you haven’t had the recommended test on time, it may help identify barriers in primary care and improve screening follow-through.
New Brunswick, New JerseyAges 50–74
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.