Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,639 recruiting studies in this area right now.
By phase
- Not applicable5,357
- Phase 2608
- Phase 1562
- Phase 3419
- Phase 4318
- Phase 1/Phase 2289
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer290
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer112
- Overweight106
- Cardiovascular Diseases104
- Amyotrophic Lateral Sclerosis101
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer89
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California523
- Maryland178
- Alabama175
- Arizona171
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,639 total
- NCT05179226RecruitingPhase 3
IV iron for children with low iron anemia
This trial studies IV ferric derisomaltose to treat iron deficiency anemia in children under 18. It is meant for children whose anemia is from a true iron problem and who either cannot tolerate or do not respond to iron taken by mouth, or have certain kidney-related causes.
Miami, FloridaAges Up to 17 years - NCT05189314Recruiting
Study of life quality changes with benign thyroid nodules
This study looks at how benign (non-cancer) thyroid nodules affect people’s day-to-day life and health outcomes. It may help doctors better understand what changes matter most to patients.
New York, New YorkAges 18 years+ - NCT05195281Recruiting
Study changes in pancreatic cancer during treatment
This study follows how pancreatic cancer changes over time while you’re receiving treatment before surgery. It may help doctors understand how the cancer evolves and guide better future treatment choices.
MilanAges 18 years+ - NCT05172089Recruiting
Treating recurring infection in diabetic foot ulcers
This trial studies an approach to treat bacteria living in a diabetic foot ulcer and help prevent the ulcer from coming back. You may be able to join if you have an open diabetic foot ulcer and good blood flow to the wound.
Tucson, ArizonaAges 18 years+ - NCT05188872Recruiting
PET scan for adrenal hormone condition before and after treatment
This trial uses a special PET scan to look at a hormone gland condition called primary aldosteronism, which can cause high blood pressure. It aims to see if the scan helps doctors plan treatment and check results.
Fuzhou, FujianAges 19–90 - NCT05166447Enrolling by invitation
Check-in study for people from the Inter99 health survey
This study is a long-term follow-up of people who took part in the Inter99 baseline exam. It involves a 3-hour check-in, and it can help researchers learn how people’s health changes over time.
Glostrup MunicipalityAges 50–82 - NCT05188014Recruiting
Exercise timing your menstrual cycle in type 1 diabetes
This study looks at how doing exercise at different points in your menstrual cycle affects blood sugar control in people with type 1 diabetes. It may help you and your care team understand how to plan exercise more safely and effectively around your period.
Edmonton, AlbertaAges 18–50 - NCT05174052RecruitingPhase 3
Dapagliflozin for heart rhythm problems in diabetes
This trial studies dapagliflozin, a diabetes medicine, to see if it can help people with paroxysmal atrial fibrillation (irregular heart rhythm). If you have both diabetes and this type of AF, the study may offer a chance to improve your heart rhythm and outcomes.
Oklahoma City, OklahomaAges 18–85 - NCT05168605Recruiting
Targeted home visits for adults with diabetes and high blood pressure
This study tests whether tailored visits from a care team at your home can improve ongoing health problems from high blood pressure and poorly controlled blood sugar. It may help you by making care easier to follow and more personalized to your daily life.
Dallas, TexasAges 18–60 - NCT05139797Recruiting
AI-guided heart ultrasound screening for suspected amyloidosis
This study tests whether an artificial-intelligence system can help decide who should get a special heart workup for a rare disease called cardiac amyloidosis. If you have signs that make doctors suspect this, the AI-guided ultrasound screening may help find it sooner.
Los Angeles, CaliforniaAges 18 years+ - NCT05179954Recruiting
Blood fat testing study in adults with and without type 1 diabetes
This study measures how “blood fats” move in the body after fasting and controlled eating, comparing people with type 1 diabetes to those without diabetes. It may help researchers understand diabetes-related differences in lipid (fat) handling and improve future treatments.
Columbia, MissouriAges 18–45 - NCT05139277Recruiting
Using a imaging system during brain tumor surgery
This study tests the CONVIVO system to help surgeons see certain brain tumors during surgery. It may help make operations safer and more effective by improving how tumors are identified.
Lebanon, New HampshireAges 18 years+ - NCT05188027Recruiting
Exercise types for postmenopausal women with type 1 diabetes
This study compares aerobic exercise (like brisk walking) versus resistance exercise (like strength training) to see which works better for women with type 1 diabetes after menopause. It may help you learn which exercise approach is safest and most helpful for blood sugar and health.
Edmonton, AlbertaAges 45–75 - NCT05153070RecruitingPhase 2
Cyclosporine then low-dose immune therapy for new type 1 diabetes
This Phase 2 study tests whether starting with cyclosporine and then giving low-dose IL-2 can better protect the body’s insulin-producing function after type 1 diabetes is diagnosed. It’s meant for people diagnosed very recently who have specific diabetes-related immune markers.
ParisAges 16–45 - NCT05189808Recruiting
Radiofrequency treatment for certain thyroid nodules
This trial studies radiofrequency ablation, a procedure that shrinks a thyroid nodule, for thyroid nodules that are unclear on biopsy but have a reassuring “molecular” test. If you have a Bethesda III nodule that tests benign on specific genetic tests, you may be a good candidate to see if this approach helps safely.
New York, New YorkAges 18 years+ - NCT05149638Recruiting
Checking updated cortisol lab values for adrenal insufficiency
This study tests whether updated cortisol test numbers better identify adrenal insufficiency, a hormone condition where your body doesn’t make enough stress hormone. It may help doctors confirm the diagnosis and choose safer next steps for treatment.
The Bronx, New YorkAges 18 years+ - NCT05193968Recruiting
Study hot flashes and blood vessel function in women
This study looks at how hot flashes relate to how well your blood vessels work in the body. It may help researchers understand the body changes behind hot flashes, which could guide future treatments.
Rochester, MinnesotaAges 40–60 - NCT05172921Recruiting
Study of environmental factors in thyroid cancer risk
This study looks at how environmental exposures may relate to thyroid cancer. If you have a suspicious thyroid nodule and are planning surgery, your biopsy or surgical tissue may be used to understand risk factors.
New York, New YorkAges 18 years+ - NCT05184790Recruiting
Using imaging during radiation therapy to improve AI planning
This study tests how well an artificial intelligence system can use special X-ray images taken during certain radiation treatments to improve care. You may qualify if you’re having radiation for specific conditions and your treatment center uses the required imaging steps.
Saint Leonards, New South WalesAges 18 years+ - NCT05173714RecruitingPhase 2
Sit Less and Move More program for people with CKD
This Phase 2 study tests a program to help people with chronic kidney disease (CKD) sit less and move more, plus a medication (semaglutide) for those who qualify. It may help improve health and day-to-day activity while monitoring safety closely.
Stanford, CaliforniaAges 20 years+ - NCT05145816RecruitingPhase 1/Phase 2
Belantamab for AL amyloidosis after prior treatments
This study tests belantamab mafodotin, a medicine designed to target amyloid-producing abnormal cells, in people with relapsed or refractory AL (light-chain) amyloidosis. It’s aimed at improving blood and organ-related signs of the disease after earlier treatments have stopped working.
Nashville, TennesseeAges 18 years+ - NCT05142033Recruiting
Cancer or precancer testing using DNA sequencing results
This trial helps doctors study and analyze cancer- or precancer-related DNA information. If you’re 18 or older and can consent, your results may help researchers understand the biology of your condition and guide future care.
Marshall, MinnesotaAges 18 years+ - NCT05183984RecruitingPhase 2
Niraparib plus bevacizumab after complete ovarian cancer surgery
This trial tests whether niraparib, taken after surgery, works better when combined with bevacizumab in people with advanced ovarian, fallopian tube, or primary peritoneal cancer who have no visible tumor left. It also aims to see if this approach helps prevent the cancer from coming back.
AngersAges 18–99 - NCT05189821Recruiting
Study treatment for tiny thyroid cancer without surgery
This trial studies a treatment option for papillary thyroid microcarcinoma in adults who either do not want surgery or cannot safely have surgery. It may help people find a non-surgical approach for a very small thyroid cancer.
New York, New YorkAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,639 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,048 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.