Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,639 recruiting studies in this area right now.
By phase
- Not applicable5,357
- Phase 2608
- Phase 1562
- Phase 3419
- Phase 4318
- Phase 1/Phase 2289
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer290
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer112
- Overweight106
- Cardiovascular Diseases104
- Amyotrophic Lateral Sclerosis101
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer89
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California523
- Maryland178
- Alabama175
- Arizona171
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,639 total
- NCT04851470Recruiting
Dental gum check in adults with obesity
This study looks at gum health in adults with obesity. It may help researchers understand how weight and related health factors affect periodontal (gum) status and what to monitor in bariatric care populations.
LondonAges 18 years+ - NCT04833907Enrolling by invitationPhase 1/Phase 2
Gene therapy study for typical Canavan disease in children
This early-phase trial tests a gene therapy medicine (delivered by a one-time infusion) for children with typical Canavan disease. It aims to improve safety and help evaluate whether the treatment may benefit children over time.
Dayton, OhioAges 3 months–5 years - NCT04786262RecruitingPhase 3
A study of VX-880 and VX-017 for type 1 diabetes
This study tests two investigational drugs, VX-880 and VX-017, for people with type 1 diabetes who have trouble controlling their blood sugar and have frequent severe low blood sugar episodes. The goal is to see if these drugs can improve blood sugar control and reduce dangerous lows.
Duarte, CaliforniaAges 18–65 - NCT04798690Recruiting
Long-term growth injections for short children
This trial studies the long-term safety and effectiveness of Growtropin®-II, a growth hormone–type injection, in children who are short due to certain causes. It may help your child’s growth over time, while also closely tracking side effects.
Seoul, Seodaemun-guAges 2 years+ - NCT04808505RecruitingPhase 3
Study of enzyme therapy for children with infant-onset Pompe disease
This trial tests how well a new enzyme treatment (cipaglucosidase alfa with miglustat) works and how safe it is in children and babies with infant-onset Pompe disease. It may help by improving muscle function after earlier treatment or, for some babies, starting treatment when no prior enzyme therapy has been given.
Gainesville, FloridaAges Up to 17 years - NCT04798430Enrolling by invitationPhase 3
Study drug follow-up for LDL reduction in high-risk cholesterol patients
This Phase 3 study looks at the long-term safety and benefit of OLE LIB003 for people with very high cholesterol or heart disease risk who still need lower LDL (“bad cholesterol”). It’s likely a continuation study for participants who already did earlier LIB003 Phase 3 trials.
Evanston, IllinoisAges 10 years+ - NCT04802395Recruiting
KidneyIntelX check for people with diabetes and early kidney disease
This study looks at how well a kidney test tool called KidneyIntelX works in real-world care for people with type 2 diabetes and certain stages of kidney disease. It may help doctors use the tool to better understand kidney risk and guide next steps.
New York, New YorkAges 23 years+ - NCT04796350Recruiting
Medicine after hip surgery to help prevent a second hip fracture
This trial tests AGN1 LOEP (a medicine/device placed at the hip surgery site) to help prevent another hip fracture after you’ve had a low-energy hip fracture. You must be eligible for hip repair surgery and be at higher risk for another fracture, with no key exclusions like active cancer or serious kidney disease.
InnsbruckAges 65–91 - NCT00289380Recruiting
Nutrition support study for hospitalized patients at risk
This trial tests how giving extra nutrition support to patients in the hospital affects health outcomes and overall costs. It may help figure out the best nutrition approach for people who are at risk while hospitalized.
Beijing, Beijing MunicipalityAges 18–80 - NCT04686682RecruitingPhase 1/Phase 2
Study drug for adults with advanced cancers or AML
This early study (Phase 1/2) tests a new medicine (JAB-8263) in adults with advanced solid tumors or recurrent/refractory AML. It aims to find a safe dose and see whether it can shrink tumors or control the cancer.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT03818178Recruiting
Study of gut-delivered fats and insulin resistance
This study looks at how sending certain fats through the intestine affects “insulin resistance,” a condition where the body doesn’t use insulin as well. If you qualify, you may receive a controlled lipid (fat) delivery as part of measuring body fat handling and related body chemistry.
Rochester, MinnesotaAges 18–55 - NCT04708431Recruiting
Study of health and wellbeing in people with androgen insensitivity
This study looks at the long-term health and wellbeing of people with androgen insensitivity, a genetic condition that affects how the body responds to androgens (male-type hormones). It may help your care team understand what to watch for over time and improve future guidance for patients and families.
Bethesda, MarylandAges 8–99 - NCT04717349Recruiting
Study collects health information for kids’ and teens’ gynecology concerns
This is a research study that gathers information about pediatric and adolescent gynecology conditions. It may help researchers better understand these issues by learning about symptoms, care, and outcomes—without requiring a specific treatment.
Bethesda, MarylandAges 1 day–100 years - NCT04714892Recruiting
Taste and smell differences in obesity
This study looks at how taste and smell may differ in people with obesity compared to healthy-weight individuals. It aims to understand why some people perceive flavors differently, which could help develop better treatments for weight management.
Bethesda, MarylandAges 18–65 - NCT04693377Recruiting
Freezing tumor treatment plus targeted radiation for painful bone spread
This study tests whether combining a “freezing” procedure (cryoablation) with focused external radiation (SBRT) can reduce pain from bone metastases. It’s for people with certain cancers that have spread to bone and are having significant pain in a specific bone spot.
Houston, TexasAges 18 years+ - NCT04715399Recruiting
Research study collecting data for neurodegenerative diseases
This study collects health information from people with neurodegenerative diseases, some family members, and healthy controls to help researchers better understand these conditions. It may help future diagnosis and research, and participation may include noninvasive checks and other procedures depending on your situation.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+ - NCT04748770Recruiting
Kidney Transplant Access for Obese Dialysis Patients
This study looks at whether obese patients who are starting dialysis can safely receive kidney transplants. Researchers want to understand how weight affects transplant success and access to this life-changing treatment.
AmiensAges 18 years+ - NCT04734626Enrolling by invitation
Leg MRI study for mitochondrial muscle weakness
This study uses an MRI scan of the lower leg to look for signs of muscle problems in people with suspected or confirmed mitochondrial disease, and compares them with healthy volunteers. Participants will lie still in the MRI and do a short, mild exercise during the scan to help the researchers see how muscles work.
Philadelphia, PennsylvaniaAges 7–75 - NCT04730622Recruiting
Studying muscle and bone changes after a hip fracture
This study looks at how bone health and muscle strength (“osteosarcopenia” — loss of both bone and muscle) change after a hip fracture in older adults. It may help doctors understand who is at higher risk and how to better support recovery after hip surgery.
BolognaAges 65 years+ - NCT04706481Recruiting
Use of stored, de-identified samples for research
This trial is for people who already agreed to let researchers use their stored biological samples and medical information that has been removed of personal identifiers. It may help future studies by allowing researchers to analyze existing samples without using new samples from you.
Hong KongAges Any age - NCT04737200Recruiting
Overnight feeding to improve sleep in ICU heart surgery patients
This trial studies whether planned overnight nutrition (through a feeding tube) can reduce sleep problems and daily body-clock disruption while you’re in the ICU after certain heart surgery. It may help you get more restful sleep and better regular “wake–sleep” timing during recovery.
Boston, MassachusettsAges 18 years+ - NCT04708535Enrolling by invitation
Study how fat changes affect insulin resistance after bariatric surgery
This study looks at how your body’s fat under the skin and inside the abdomen may affect “insulin resistance,” a common problem linked with blood sugar control. It’s for people who are scheduled for bariatric (weight-loss) surgery, to learn more before and after surgery.
Stanford, CaliforniaAges 30–65 - NCT04721197Recruiting
Hens hatching hope for babies in Honduras
This study involves a “hens hatching hope” program for young children in Intibucá, Honduras to support early development. Your child may be able to join if they are healthy, the right age, and have no egg allergy.
Concepción, Intibucá DepartmentAges 6 months–2 years
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,639 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,048 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.