Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,640 recruiting studies in this area right now.
By phase
- Not applicable5,354
- Phase 2609
- Phase 1563
- Phase 3420
- Phase 4318
- Phase 1/Phase 2290
- Phase 2/Phase 386
Top conditions
- Obesity617
- Ovarian Cancer337
- Pancreatic Cancer290
- Type 2 Diabetes277
- Diabetes191
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome128
- Obesity & Overweight125
- Breast Cancer112
- Overweight105
- Cardiovascular Diseases104
- Amyotrophic Lateral Sclerosis101
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer89
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California524
- Maryland178
- Alabama175
- Arizona171
- Florida164
- Texas159
- Massachusetts151
- New York143
- Colorado115
- Pennsylvania114
Recruiting studies7,640 total
- NCT04404530Recruiting
Study nutrition changes from Palynziq in adults with PKU
This study looks at how taking Palynziq affects your nutrition and health in people with phenylketonuria (PKU). You might benefit by getting careful monitoring while researchers learn how the medicine changes diet-related measurements.
Atlanta, GeorgiaAges 16 years+ - NCT01851694Recruiting
Study incretin hormone response in adults with cystic fibrosis
This study tests how the body’s “incretin” hormones affect insulin (sugar control) in adults with cystic fibrosis and certain blood sugar patterns. It may help explain what drives diabetes risk in cystic fibrosis and how the body responds to these hormone signals.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04440254Recruiting
Long ECG monitoring for Fabry disease heart rhythm
This study checks how your heart’s electrical rhythm looks over a longer period using an ECG (a heart rhythm recording) in people with Fabry disease. It may help doctors understand heart rhythm changes better so future care can be more tailored and safer.
Paris, ParisAges 18 years+ - NCT04466189Enrolling by invitation
Pancreatic cancer patients receiving proton beam treatment
This study follows people with pancreatic cancer who are planning to receive proton beam therapy. It’s meant to learn about their care and outcomes after this treatment, and you would join by agreeing to participate.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT04439708Recruiting
Biomarkers for abnormal eye blood vessels
This study is looking for biomarkers (clues in your body) related to abnormal blood vessels in the eye. It may help researchers understand and treat conditions like macular degeneration.
ParisAges 18–90 - NCT04419870Recruiting
Acute infections in people with mitochondrial disease
This study looks at how people with mitochondrial disease respond to acute infections like COVID-19 or the flu. It aims to understand how infections affect the body and to find better ways to care for patients.
Bethesda, MarylandAges 2 months–115 years - NCT04461821Recruiting
Breath test to study disease in children
This study uses a special machine to analyze exhaled breath to learn about different illnesses in children and teens. It may help researchers find breathing “signals” that reflect conditions like breathing problems, nervous system issues, or new/worsening type 1 diabetes.
BaselAges Up to 22 years - NCT04451915Recruiting
Study for early gestational diabetes in pregnancy
This study is looking at pregnant people who have early signs of gestational diabetes in the first half of pregnancy. It may help find safer ways to monitor or treat early diabetes-related blood sugar changes to improve pregnancy outcomes.
ArrasAges 18 years+ - NCT04406831Recruiting
Testing microRNA for pancreatic cancer diagnosis and treatment response
This study looks at tiny molecules in your body (microRNA) to help doctors better diagnose pancreatic cancer, predict how it may progress, and understand how it responds to treatment. It may help guide more personalized care in the future.
Norwalk, ConnecticutAges 18 years+ - NCT04485286RecruitingPhase 2
PET scan tracer to find lung or pancreas radiation injury
This Phase 2 study tests a special PET scan tracer to help doctors spot tissue damage after radiation treatment in people with certain lung or pancreatic cancers. The goal is to improve detection and planning around chemoradiation and surgery.
Boston, MassachusettsAges 18–80 - NCT04403074Recruiting
Procedure for pancreas pain in chronic pancreatitis
This trial tests an endoscopy-based procedure called celiac plexus neurolysis to reduce pain from chronic pancreatitis. It may help people whose pancreas pain has not been adequately controlled with other treatments.
Indianapolis, IndianaAges 18 years+ - NCT04454216Recruiting
Liver enzyme gene study for GSD VI or GSD IX
This study looks at the natural history (how the illness typically progresses) in people with GSD VI or GSD IX. It may help doctors better understand disease patterns, which can support future treatments.
Durham, North CarolinaAges birth–90 years - NCT04442451Recruiting
Study how fatigue happens in prediabetes and type 2 diabetes
This study looks at why people with prediabetes or type 2 diabetes may feel unusually tired during activities. You may be asked to do exercise testing and answer questions to help researchers understand the body changes behind fatigue.
Ann Arbor, MichiganAges 30–85 - NCT04460573RecruitingPhase 2
Using a smart boot to improve diabetic foot offloading
This trial studies whether a special “smart boot” can help people with diabetic foot ulcers rest (offload) the affected foot as they should. Better offloading may improve healing by reducing pressure on the wound.
Downey, CaliforniaAges 18 years+ - NCT04393701Recruiting
Testing newborn blood spots to check for rare storage diseases
This pilot study tries a systematic way to look for several rare “lysosomal storage” diseases in newborns using a specialized lab test on routine blood samples. It may help detect these conditions earlier so treatment can start sooner if needed.
CaenAges 1 day–4 days - NCT04464070Enrolling by invitationEarly Phase 1
Study of how your body processes natural inflammation signals
This early study looks at how the body breaks down certain natural inflammation-related chemicals (“eicosanoids”). It aims to understand normal metabolism pathways, and you may help by sharing how your body responds while you avoid certain medicines.
Nashville, TennesseeAges 18–65 - NCT04485871Recruiting
Omega-3 supplements to lower diabetes risk in at-risk adults
This trial tests whether taking omega-3 fatty acids can reduce risk factors for developing diabetes in people with normal cholesterol but other risk factors. You might be asked to follow study visits and dietary/health restrictions for about 33 weeks.
Montreal, QuebecAges 45–74 - NCT04431232Recruiting
Gastric banding during endoscopy to help with weight loss
This trial studies an endoscopic procedure that places a band inside the stomach to help reduce weight. You may be considered if your body weight is above a certain level and you’re able to safely undergo an endoscopy.
Giza, DokkiAges 18–65 - NCT04473794Recruiting
Testing ways to assess pancreatic cyst risk and progression
This study looks at patients who have been referred for evaluation of a pancreatic cyst. It aims to improve how doctors estimate risk and predict how cysts may change over time.
Baltimore, MarylandAges 18 years+ - NCT04394806Recruiting
Fasting and meal-fat study in early pregnancy
This study looks at how fasting and eating affect a pregnancy’s fat levels in the belly and liver. It may help researchers understand how maternal metabolism could impact baby and pregnancy health.
Aurora, ColoradoAges birth–39 years - NCT04388969Recruiting
Ambroxol study for Gaucher disease and Parkinson symptoms
This trial looks at ambroxol, a medicine, for people who have Gaucher disease and Parkinson disease that is linked to Gaucher. If you fit the condition group, the study may help doctors learn whether ambroxol can improve Parkinson-related symptoms in this specific situation.
Jerusalem, Please Select...Ages Up to 100 years - NCT04453072Recruiting
iPhone weight-loss app for teens and young adults after transplant
This study tests whether an iPhone weight-management app can help adolescents and young adults lose weight after a stem cell transplant. If you qualify, you’ll use the app and the team will track changes in weight.
Los Angeles, CaliforniaAges 13–30 - NCT04477928Recruiting
Checking type 1 diabetes risk using routine child care
This study estimates the chance of developing type 1 diabetes in children by using information gathered during regular well-child visits. It may help identify children who could benefit from earlier monitoring.
Bemidji, MinnesotaAges birth–17 years - NCT04414046RecruitingPhase 2
Stem cell transplant using T-cell cleanup for immune and metabolism disorders
This Phase 2 study tests a specialized stem cell transplant that removes certain “T-cells” (a type of immune cell) to treat children with serious immune system or inherited metabolic problems. The goal is to improve or stabilize disease by resetting the immune system and supporting the body’s function.
St. Petersburg, FloridaAges Up to 21 years
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,640 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,087 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.