Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT07261345RecruitingEarly Phase 1
CAR-T cell therapy for hard-to-treat Graves' disease
This early-phase trial tests whether specially engineered immune cells (called CAR-T) can treat Graves' disease that hasn't responded to standard medication. It's for people with active, hard-to-control Graves' who have the TRAb antibody.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07261891Recruiting
Lab study of JAK-STAT related disorders
This study looks at blood or tissue samples from people with certain genetic disorders that affect a key cell communication pathway (JAK-STAT). The goal is to learn more about these disorders and test potential treatments in the lab.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07262450Recruiting
Seawater spray for stuffy nose and sinus symptoms
This trial tests whether a seawater nasal spray can relieve nasal congestion, runny nose, and other sinus symptoms in people with colds, allergies, or after nose surgery. You will use the spray as directed and answer online questionnaires for up to 3 months.
BordeauxAges 2 weeks+ - NCT07262476RecruitingPhase 3
Extension study of MHB018A for thyroid eye disease
This study tests a longer-term use of MHB018A for people with thyroid eye disease who did not fully respond to treatment in a previous study. It aims to see if further treatment can help improve eye bulging and other symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07263490Recruiting
Pre-eclampsia Risk in Egg Recipients Study
This study looks at whether women who become pregnant after receiving donated eggs have a higher risk of developing pre-eclampsia (a serious blood pressure condition) during pregnancy. It aims to understand risks so doctors can better support pregnant women.
CopenhagenAges 18 years+ - NCT07263685Recruiting
Study of takhzyro (lanadelumab) for teens and adults with HAE in Saudi Arabia
This study looks at how well Takhzyro (lanadelumab) works for people with a specific type of hereditary angioedema (HAE) that is caused by a C1 inhibitor deficiency. It is for teenagers and adults who have already been taking Takhzyro for at least 6 months.
RiyadhAges 12 years+ - NCT07264101Recruiting
Balance test study for people with rheumatoid arthritis
This study tests a simple balance test (the Four Square Step Test) in people with rheumatoid arthritis. It aims to see how reliable and valid this test is for measuring your ability to move and stay steady.
MalatyaAges 18–65 - NCT07264426Recruiting
Real-world study of efgartigimod for CIDP
This study looks at how well efgartigimod works in everyday use for people with chronic inflammatory demyelinating polyneuropathy (CIDP). It aims to understand the real-world benefits of this treatment.
Wilmington, North CarolinaAges 18 years+ - NCT07266181RecruitingPhase 1
CAR-T cell therapy for tough-to-treat membranous nephropathy
This trial tests whether specially engineered immune cells (CAR-T cells) can help people with a kidney condition called primary membranous nephropathy that has not improved with standard treatments. The goal is to see if this therapy can reduce protein in the urine and protect kidney function.
Xi'an, ChinaAges 18 years+ - NCT07266805RecruitingPhase 3
Oral deucrictibant for preventing and treating angioedema attacks in AAE-C1INH
This trial tests two forms of an oral medication to prevent and treat sudden swelling attacks in people with a rare condition called acquired angioedema due to C1 inhibitor deficiency. It aims to see if the drug can reduce attack frequency and manage acute episodes.
San Diego, CaliforniaAges 18 years+ - NCT07268326Recruiting
Plant-based diet for rheumatoid arthritis
This trial tests whether a plant-based diet can help people with rheumatoid arthritis who have mild disease activity. You must have had RA for at least a year, be on stable medication, and not smoke or take prednisolone.
FrederiksbergAges 18 years+ - NCT07268768Recruiting
Personality, thinking, and sensitivity in headache
This study looks at how personality, thinking skills, and heightened nerve sensitivity are connected in people with headache. It aims to better understand these relationships to improve care.
Messina, SicilyAges 18–60 - NCT07268846Recruiting
Prebiotic supplement before colorectal cancer surgery
This trial tests if taking a postbiotic supplement before surgery for colorectal cancer can improve recovery. It may help patients with adenocarcinoma of the large intestine prepare for their operation.
São Paulo, São PauloAges 18 years+ - NCT07270172Recruiting
Micronutrient study for type 1 diabetes complications
This study tests how a specific drug affects heart and kidney health in people with type 1 diabetes who already have some complications like kidney disease, heart problems, or obesity. It aims to find new ways to prevent further damage.
Aarhus NAges 40 years+ - NCT07270263Recruiting
Lower-dose blood thinners for people with blood cancers
This trial compares lower doses of two common blood thinner pills (apixaban and rivaroxaban) to a daily injection (enoxaparin) to prevent blood clots in people receiving treatment for blood cancers like multiple myeloma, lymphoma, or certain other blood cancers.
Gdansk, Pomeranian VoivodeshipAges 18 years+ - NCT07270679Recruiting
Genetic markers for ovarian damage after chemo
This study is looking for genetic markers that may help predict how chemotherapy affects the ovaries. It's for women who had breast cancer or lymphoma, froze their ovarian tissue before treatment, and finished that treatment at least 6 months ago.
Bologna, BolognaAges 18–38 - NCT07270835RecruitingPhase 4
Zanubrutinib plus rituximab for HLH with B-cell lymphoma
This study tests a combination of two drugs—zanubrutinib and rituximab—to treat HLH that happens in people with B-cell lymphoma. It aims to see if this treatment is safe and works better.
Suzhou, JiangsuAges 14–80 - NCT07270861Recruiting
Study of peripheral T-cell lymphoma outcomes in real-world care
This study is looking at how peripheral T-cell lymphoma (PTCL) behaves and responds to treatment in real-world settings. It includes patients diagnosed over many years to better understand the disease and improve care.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07271667RecruitingPhase 2
Study of emavusertib with zanubrutinib for CLL and other B-cell cancers
This trial combines an experimental drug, emavusertib, with zanubrutinib (a standard targeted therapy) for people with chronic lymphocytic leukemia (CLL) or other B-cell cancers. It aims to see if the combination can improve response in patients who still have some disease despite taking zanubrutinib or whose disease has worsened on it.
Miami Beach, FloridaAges 18 years+ - NCT07272499RecruitingPhase 2
New drug combo for untreated high-risk mantle cell lymphoma
This trial tests a combination of three drugs (orelabrutinib, lisaftoclax, and rituximab) for people with mantle cell lymphoma who have not had treatment before and have high-risk features. The goal is to see if this combination works better than standard treatments.
Shanghai, Shanghai MunicipalityAges 14 years+ - NCT07273903Recruiting
Tracking CIDP treatment with a smartwatch
This trial tests whether a smartwatch can help monitor how well subcutaneous immunoglobulin (fSCIG) works for people with CIDP who recently switched from IVIG or plan to switch. It aims to make treatment tracking easier and more convenient.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT07274059RecruitingEarly Phase 1
CAR-T cell therapy from cord blood for lupus
This trial tests a new CAR-T cell treatment made from donor umbilical cord blood for people with lupus that hasn't improved with at least two standard treatments. The goal is to see if it can help control disease activity.
Yancheng, JiangsuAges 18–75 - NCT07274631Recruiting
Study of inflammatory lung diseases
This study collects information from people with various inflammatory lung conditions, like asthma or COPD, to better understand them and improve treatment. Healthy volunteers are also needed for comparison.
ReimsAges 18 years+ - NCT07275190Recruiting
Machine learning to tell apart two rare diseases
This trial uses computer models (machine learning) to help doctors better distinguish between two rare conditions that both cause high levels of a certain white blood cell (eosinophil). The goal is to make diagnosis faster and more accurate, which could lead to more targeted treatment.
PaviaAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.