Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 3,966 recruiting studies in this area right now.
By phase
- Not applicable2,544
- Phase 2357
- Phase 4302
- Phase 1287
- Phase 3286
- Phase 1/Phase 2131
- Phase 2/Phase 359
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris69
- University of California, San Francisco39
- Johns Hopkins University30
- National Cancer Institute (NCI)28
- Hospices Civils de Lyon27
- Columbia University24
- University of Washington23
- University of Alabama at Birmingham22
- University of Oxford22
Where studies are running
- California234
- Maryland142
- Alabama92
- New York73
- Florida72
- Texas63
- Massachusetts55
- Arizona48
- Pennsylvania44
- Illinois41
Recruiting studies3,966 total
- NCT06339203Recruiting
Saline vs. special antiseptic for c-section wound cleaning
This study compares cleaning the wound with plain salt water versus a diluted antiseptic solution after a planned C-section. The goal is to see which method better prevents infections for mothers with certain health conditions.
Loma Linda, CaliforniaAges 18 years+ - NCT06340737RecruitingPhase 1
CD22-targeting CAR T cells for relapsed B cell lymphoma
This trial tests whether giving modified immune cells (CAR T cells) that target CD22 on cancer cells can help people with certain B-cell lymphomas that have come back or not responded to at least two prior treatments. The goal is to see if this approach can shrink tumors or control the disease.
Palo Alto, CaliforniaAges 18 years+ - NCT06358209Recruiting
Washing the brain for infection treatment
This study tests whether washing out the infected fluid spaces in the brain (ventricular irrigation) can safely treat a serious brain infection (ventriculitis). It is for adults with a confirmed infection and fever who are stable enough for the procedure.
Hefei, AnhuiAges 18–65 - NCT06344819RecruitingPhase 2
Acupuncture for People at High Risk of Sepsis
This study tests whether acupuncture can help people at high risk for sepsis, a serious infection that can lead to organ failure. If you’re 18 or older, have had a sepsis order set put in within the last two days, and are not yet in the ICU, you may be able to join.
Irvine, CaliforniaAges 18 years+ - NCT06358872RecruitingPhase 4
Azithromycin for child survival in Niger
This study tests if giving azithromycin to women and young children in rural Niger can reduce deaths and track antibiotic resistance. It aims to improve child survival in communities where access to healthcare is limited.
NiameyAges 1 month–4.9 years - NCT06350682Enrolling by invitation
HIV prevention app study for young men
This study tests a smartphone program to help young men who have sex with men stay healthy and prevent HIV. It's designed for people already getting care at certain clinics.
Abuja, NigeriaAges 15–24 - NCT06352970Recruiting
TB infection and placenta function study
This study looks at how tuberculosis (TB) infection might affect the placenta and its function during pregnancy. If you are pregnant and giving birth soon, researchers want to learn if TB changes how the placenta grows and works.
Addis AbabaAges 18 years+ - NCT06318416RecruitingPhase 1
Precision Rifampin Dosing for TB
This study tests whether giving a personalized dose of rifampin (a key TB medicine) can improve treatment. It is for people with active TB that is sensitive to rifampin, and it involves frequent blood and urine tests to measure drug levels.
HaydomAges 3 years+ - NCT06334341Enrolling by invitation
Study to improve PrEP use in primary care
This trial tests ways to help primary care providers and their patients start using PrEP, a daily pill that prevents HIV. It may be right for you if you are interested in HIV prevention.
Detroit, MichiganAges 18 years+ - NCT06331364Recruiting
Treating lung infections with better antibiotic decisions in Sri Lanka
This study tests whether a new way of deciding when to use antibiotics helps patients with lower respiratory infections (like pneumonia or bronchitis) in Sri Lankan hospitals. If you were recently admitted with a new lung infection, you may be able to join.
BalapitiyaAges 14 years+ - NCT06325293Recruiting
Macrolide vs. placebo for mycoplasma pneumonia in children
This trial tests whether azithromycin (a macrolide antibiotic) is better than a placebo for treating mycoplasma pneumonia in children aged 3–17. If your child has pneumonia caused by mycoplasma, this study may help find the best treatment.
Aarau, Canton of AargauAges 3–17 - NCT06326008RecruitingPhase 1
Donor immune cell therapy for leukemia that returned after treatment
This trial tests a two-step approach using donor immune cells to treat children with B-cell acute lymphoblastic leukemia (B-ALL) that has come back or not responded to standard treatments. First, a donor's CD19-targeted cells are given to bridge to a stem cell transplant, followed by CD22-targeted cells to prevent relapse.
Beijing, Beijing MunicipalityAges 1–18 - NCT06337292RecruitingPhase 3
Wound vacuum therapy for high-risk leg fractures
This trial tests if a special wound vacuum (negative pressure therapy) applied after surgery can lower the risk of infections and other complications in people with severe leg fractures. If you have a high-risk tibia or ankle fracture, this treatment may help you heal better.
Baltimore, MarylandAges 18 years+ - NCT06319248RecruitingPhase 2
Midodrine to treat sepsis and reduce IV vasopressors
This trial tests if the oral medication midodrine can help wean patients with sepsis off IV vasopressors faster, potentially reducing ICU stays and complications.
Scottsdale, ArizonaAges 18 years+ - NCT06321536RecruitingPhase 2
Testing microbiota therapy for resistant bacteria in the gut
This study tests a treatment made from healthy donor stool (called microbiota therapy) given as an enema or through a feeding tube. It aims to help people who carry resistant bacteria that are hard to treat, by reducing or clearing those bacteria from the gut.
Atlanta, GeorgiaAges 18 years+ - NCT06336317RecruitingPhase 4
Flu vaccine after heart attack: effect on heart inflammation
This trial tests whether getting a flu vaccine shortly after a heart attack can reduce inflammation in the heart. If you've recently had a non-ST-segment elevation heart attack and a stent placed, you may be able to join.
AarhusAges 18 years+ - NCT06323226Recruiting
Sepsis long-term outcomes in critically ill children
This study looks at how sepsis (a severe infection that can affect the whole body) affects children after they leave the intensive care unit. It compares children who had sepsis to those with other critical illnesses to understand long-term health.
Chengdu, SichuanAges birth–16 years - NCT06334497RecruitingPhase 3
Combination antiviral therapy for CMV in kidney transplant
This trial tests a combination of two antiviral drugs (letermovir and valganciclovir) to treat CMV infections in kidney transplant recipients. It aims to find a safer, more effective treatment option for people with active CMV after transplant.
ParisAges 18 years+ - NCT06326476RecruitingEarly Phase 1
Siplizumab injection for moderate to severe hidradenitis suppurativa
This study tests an injected drug called siplizumab for people with moderate to severe hidradenitis suppurativa (HS) that hasn't improved with other treatments. The goal is to see if it safely reduces painful bumps and improves your skin condition.
Birmingham, AlabamaAges 18 years+ - NCT06310551RecruitingPhase 1
Long-acting HIV prevention study for healthy adults
This study tests a new long-acting medicine that may help prevent HIV. It is given as an injection, and the study checks how safe it is and how it works in healthy volunteers.
Lenexa, KansasAges 18–55 - NCT06300138Recruiting
Antifungal and heat therapy for sporotrichosis
This study is testing two treatments—antifungal medicine and a special heat lamp (infrared)—separately or together for sporotrichosis, a skin fungus. The goal is to find what works best with fewer side effects.
ShenyangAges Any age - NCT06306300RecruitingPhase 4
Hepatitis C treatment at local clinics vs standard care
This study compares two ways to treat hepatitis C: getting treatment at a local clinic near you, or the usual care at a central hospital. It aims to see if treatment at local clinics is safe, effective, and more convenient for patients.
Rio de Janeiro, Rio de JaneiroAges 18–79 - NCT06307977Recruiting
Couples counseling to reduce drug use and HIV risk
This study tests a couple-focused counseling approach to help male couples reduce drug use and lower the risk of HIV. You and your partner would join sessions together to talk about safer choices and support each other.
Detroit, MichiganAges 18–55 - NCT06311006Recruiting
Safety registry for fecal transplant for C. diff
This registry tracks people who receive a fecal microbiota transplant (FMT) for a serious or repeat C. diff infection. It helps doctors better understand how safe and effective FMT is in real-world use.
ParisAges 18 years+
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 3,966 recruiting infectious disease studies from the U.S. registry right now, out of 6,624 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.