Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 3,966 recruiting studies in this area right now.
By phase
- Not applicable2,544
- Phase 2357
- Phase 4302
- Phase 1287
- Phase 3286
- Phase 1/Phase 2131
- Phase 2/Phase 359
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris69
- University of California, San Francisco39
- Johns Hopkins University30
- National Cancer Institute (NCI)28
- Hospices Civils de Lyon27
- Columbia University24
- University of Washington23
- University of Alabama at Birmingham22
- University of Oxford22
Where studies are running
- California234
- Maryland142
- Alabama92
- New York73
- Florida72
- Texas63
- Massachusetts55
- Arizona48
- Pennsylvania44
- Illinois41
Recruiting studies3,966 total
- NCT05224583Enrolling by invitation
Study BK virus after combined liver and kidney transplant
This study looks at how often BK virus shows up in people after a combined liver-kidney transplant. It may help the transplant team better predict and manage this virus after surgery.
Dallas, TexasAges 18–100 - NCT05202964Recruiting
Study comfort and safety with oral antibiotics for bone joint infection
This trial studies how tolerable (comfortable) and safe oral antibiotic treatment is for infections in bones or joints. It may help confirm whether taking antibiotics by mouth for at least 6 weeks is well tolerated during treatment.
LyonAges 18 years+ - NCT05244967Recruiting
Study of sexually transmitted infections and female fertility impact
This study looks at how sexually transmitted infections affect female fertility. It mainly enrolls young adults to better understand patterns and outcomes over time.
LübeckAges 18–22 - NCT05189925RecruitingPhase 1
Correcting a missing immune enzyme using an mRNA cell therapy
This early-phase trial tests whether an mRNA-based treatment can correct a key immune problem in people with chronic granulomatous disease (CGD). It may help your immune cells work better against infections, but this is mainly to check safety and early signs of benefit.
Bethesda, MarylandAges 18–75 - NCT05181826Recruiting
Blood collection study for cancer and benign diseases
This study collects blood samples from people with different health conditions (cancer, diabetes, liver disease, etc.) and from healthy volunteers. The goal is to find markers in the blood that could help detect or monitor diseases.
Redondo Beach, CaliforniaAges 18 years+ - NCT05143307Enrolling by invitationPhase 1
Follow-up study for adults who received EBT-101 for HIV
This study checks how adults are doing long-term after receiving an HIV treatment called EBT-101 in an earlier study. It helps researchers understand safety and longer-term effects over time.
San Francisco, CaliforniaAges 18 years+ - NCT05147519Recruiting
Observes HIV and other infections to learn who gets them
This is an observational study that follows people to better understand how HIV and other infections (like sexually transmitted infections) happen and change over time. It may help researchers improve prevention and care, but it is mainly for monitoring rather than testing a new treatment.
Kericho, Kericho CountyAges 14–55 - NCT05172089Recruiting
Treating recurring infection in diabetic foot ulcers
This trial studies an approach to treat bacteria living in a diabetic foot ulcer and help prevent the ulcer from coming back. You may be able to join if you have an open diabetic foot ulcer and good blood flow to the wound.
Tucson, ArizonaAges 18 years+ - NCT05164744Recruiting
MRI study of heart tissue changes after COVID-19
This study uses a heart MRI to look for leftover (healing) changes in heart tissue after COVID-19. It may help researchers better understand what ongoing heart effects can happen after infection.
Brooklyn, New YorkAges 18 years+ - NCT05159739Enrolling by invitation
Study of family genetic risk for joint implant infections
This study looks at whether certain families have a higher genetic risk for infections around joint implants. It may help researchers understand who is more at risk and how to prevent these infections.
Salt Lake City, UtahAges 18–100 - NCT05179499RecruitingPhase 3
Early norepinephrine for low blood pressure in sepsis
This Phase 3 trial tests whether starting a medicine called norepinephrine early can improve outcomes for adults with sepsis (a serious body-wide response to infection) and low blood pressure. You might be considered if you’re very early in hospital care and meet specific blood pressure and lactate tests.
AintreeAges 18 years+ - NCT05148286RecruitingPhase 4
Testing albumin vs fluids for septic shock in the ER
This trial tests whether giving albumin instead of standard crystalloid fluids helps adults with septic shock. It may improve how well your body circulates blood and reduces strain on organs.
SeoulAges 18 years+ - NCT05183490RecruitingPhase 1
Cell therapy for repeated viral infections after transplant
This early-phase (Phase 1) study tests an immune cell treatment (R-MVST) to help people whose immune system has been weakened by a past transplant and who keep getting viral infections reactivated or not responding well to standard treatment. It may help your body control viruses like EBV, CMV, adenovirus, or BK virus.
New York, New YorkAges 18 years+ - NCT05188612Recruiting
Hospital patients with confirmed COVID-19 survey study
This study collects information from adults who are in the hospital for confirmed COVID-19. The goal is to better understand what happens during acute (early) COVID-19 and improve care.
Bologna, BolognaAges 18 years+ - NCT05190978Recruiting
Test mesh use for breast reconstruction above the muscle
This study tests whether using surgical mesh can be done safely and works well in breast reconstruction done right away, in front of the chest muscle (pre-pectoral) using tissue expanders. It may help improve how the reconstructed area holds up, but you’d need to meet specific surgical and health requirements.
Los Angeles, CaliforniaAges 22–75 - NCT05137119RecruitingPhase 4
Adaptive study of treatments for staph bloodstream infection
This trial tests the best treatment approach for bloodstream infections caused by Staphylococcus aureus (“S. aureus”). It uses a flexible design to decide which treatment track you fit into, and may help improve recovery while avoiding unnecessary medications.
Houston, TexasAges Any age - NCT05192057RecruitingPhase 4
Inhaling salty steam for lung MAC infection
This trial studies whether inhaling hypertonic (very salty) saline helps treat nodular-bronchiectatic lung disease caused by Mycobacterium avium complex (MAC). It may help reduce ongoing infection and symptoms if you have the right type of MAC lung pattern and have not recently started the usual MAC treatments.
NijmegenAges 18 years+ - NCT05141058RecruitingPhase 1
T cell therapy to help prevent COVID-19 after transplant
This Phase 1 trial tests a donated immune-cell treatment (T cells) to help immunocompromised people fight or resist COVID-19 after they recently received a bone marrow or stem cell transplant. It aims to see if the treatment is safe and if it helps the body respond better to the virus.
Washington D.C., District of ColumbiaAges 2–80 - NCT05077527RecruitingPhase 1
CAR-T treatment for HIV and aggressive B-cell lymphoma
This trial studies a lab-made immune cell treatment (CAR-T) for adults who have HIV and aggressive B-cell non-Hodgkin lymphoma that has come back or did not respond to prior treatment. It aims to see if the treatment can control the lymphoma safely in this specific group.
Duarte, CaliforniaAges 18 years+ - NCT05075967Enrolling by invitation
Study attitudes and services among southern gay and bisexual men
This study gathers opinions and experiences from gay and bisexual men and from clinic staff in the American South. It helps researchers understand what affects HIV prevention and care, and how programs can better support people at higher risk.
Durham, North CarolinaAges 15 years+ - NCT05086692RecruitingPhase 1/Phase 2
Beta-only IL-2 therapy for advanced solid tumors
This Phase 1/2 study tests a beta-only version of IL-2, an immune-stimulating treatment, to shrink or control advanced or metastatic solid tumors. It’s mainly designed to check safety and to see if it can help patients by improving tumor response.
San Diego, CaliforniaAges 18 years+ - NCT05095701Enrolling by invitationPhase 4
Study tracks lasting protection from a live chickenpox vaccine
This trial follows people who previously took a chickenpox (varicella) vaccine to see how long their immune protection lasts. It may help explain who stays protected over time and for how long.
Xuchang, HenanAges 1–17 - NCT05076760RecruitingPhase 1
Study of a cancer-killing virus with standard treatments
This Phase 1 trial tests MEM-288, an oncolytic (cancer-killing) virus, either alone or combined with standard cancer medicines, in people with advanced solid tumors. It’s designed to see how the treatment works and how safe it is in different cancer types and after specific prior therapies.
Tampa, FloridaAges 18 years+ - NCT05075252Recruiting
Testing whether contamination level matters during laparoscopic appendicitis surgery
This study looks at appendicitis patients having laparoscopic surgery and tests whether the amount of contamination found during surgery affects outcomes. It may help surgeons choose the best way to clean the abdomen during the operation.
MilanAges 18–69
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 3,966 recruiting infectious disease studies from the U.S. registry right now, out of 6,624 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.