Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 4,171 recruiting studies in this area right now.
By phase
- Not applicable2,706
- Phase 2361
- Phase 4322
- Phase 1290
- Phase 3285
- Phase 1/Phase 2142
- Phase 2/Phase 365
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris80
- University of California, San Francisco44
- Johns Hopkins University32
- Hospices Civils de Lyon30
- National Cancer Institute (NCI)28
- University of Washington27
- University Hospital, Strasbourg, France26
- Columbia University23
- University of Alabama at Birmingham23
Where studies are running
- California235
- Maryland147
- Alabama89
- New York77
- Florida74
- Texas61
- Massachusetts56
- Arizona47
- Pennsylvania45
- Illinois42
Recruiting studies4,171 total
- NCT05654883Enrolling by invitation
Study of mpox immunity in people who were vaccinated or infected
This observational study looks at how your body’s defenses work against mpox (monkeypox), based on blood and health information. You may be eligible if you recently got an mpox vaccine or have had mpox infection and are now out of isolation.
New York, New YorkAges 18–100 - NCT04419870Recruiting
Acute infections in people with mitochondrial disease
This study looks at how people with mitochondrial disease respond to acute infections like COVID-19 or the flu. It aims to understand how infections affect the body and to find better ways to care for patients.
Bethesda, MarylandAges 2 months–115 years - NCT07096193RecruitingPhase 1/Phase 2
Study of GS-4321 for chronic hepatitis delta
This trial tests a new drug, GS-4321, for people with chronic hepatitis delta, a serious liver infection. It aims to see if the drug is safe and effective, and compares results in healthy volunteers and those with the virus.
Anaheim, CaliforniaAges 18–69 - NCT07628140Recruiting
Home-Based TB Prevention Treatment in Kenya
This study tests a community-friendly way to deliver TB prevention medicine (called TPT) to people's homes in Kenya. Researchers want to see if bringing screening and treatment to your house—instead of making you go to a clinic—helps more people start and finish TB prevention, which can reduce TB spread in your community.
KisumuAges Any age - NCT07703891Recruiting
Testing B-OK Bottles for HIV Medication Understanding in South Africa
This study tests a special 'B-OK' bottle designed to help people understand their HIV medication better. If you live in Gauteng and can come to the study offices for one visit, you might help find better ways to support HIV treatment with simple tools.
Johannesburg, GautengAges 18 years+ - NCT07544589RecruitingPhase 1
Testing DISP-10 for Advanced Gastrointestinal Cancers
This early-stage trial tests a new experimental therapy called DISP-10 in patients with advanced cancers of the stomach, esophagus, or colon that have spread. The goal is to see if this treatment can help shrink tumors and how safe it is.
Duarte, CaliforniaAges 18 years+ - NCT05858034Recruiting
Study of aging and frailty in people with HIV over 50
This study looks at what makes some people with HIV become “pre-frail” or frail as they get older. It uses questionnaires and other checks to understand challenges to healthy aging and may help improve future support and care.
Winston-Salem, North CarolinaAges 50 years+ - NCT06932003RecruitingPhase 1/Phase 2
Testing a new tablet for hidradenitis suppurativa
This trial is testing an experimental tablet called LT-002-158 in adults with moderate to severe hidradenitis suppurativa (HS) that hasn't improved enough with standard treatments. The goal is to see if it's safe and helps reduce painful lumps and abscesses.
Beijing, Beijing MunicipalityAges 18–75 - NCT02127398RecruitingPhase 2
Fecal transplants for hard-to-treat C. difficile infection
This Phase 2 study tests whether placing stool from a healthy donor into your gut can treat repeated, hard-to-control C. difficile colitis. It may help restore healthy gut bacteria and reduce future flare-ups.
Durham, North CarolinaAges 18 years+ - NCT04232917RecruitingPhase 4
Testing a treatment to help clear genital high-risk HPV
This trial studies 2LPAPI® to see if it helps the body clear high-risk HPV infections in the cervix. It may be an option if you have a current HPV infection with mild/early abnormal cervical findings and can complete follow-up for about a year.
BrusselsAges 25–45 - NCT05568966Recruiting
Blood sample collection for new diagnostic tests
This study collects small blood samples to help test and improve new diagnostic devices. You may be eligible if you’re an adult with certain symptoms that match one of several health “groups,” and if you can consent and read English.
Airdrie, ScotlandAges 18 years+ - NCT07725939RecruitingPhase 2
Study of Galvokimig for moderate-to-severe COPD with chronic bronchitis
This study tests an experimental drug called Galvokimig (taken as a pill) to see if it can reduce COPD flare-ups and improve lung function in people with moderate to severe COPD and chronic bronchitis. It is for those who have had recent flare-ups and are already using maintenance inhalers.
Columbus, OhioAges 40–80 - NCT05288790RecruitingPhase 2
Study how gut chemicals and alcohol affect heart risk in HIV
This Phase 2 study looks at how “microbiome metabolites” (chemicals from gut bacteria) and alcohol may affect heart and blood vessel risk in people living with HIV. If you qualify, you may be asked to follow a study plan to see how these factors change health markers related to cardiovascular disease.
Nashville, TennesseeAges 18–89 - NCT07788404Recruiting
Study of rifampin levels in patients with bone or joint staph infections
This study looks at how the antibiotic rifampin behaves in the body when used to treat staph infections in bones or joints. It may help doctors better dose the drug for future patients.
Paris, ParisAges 18 years+ - NCT07654283RecruitingPhase 2
Study of AHB-137 for chronic hepatitis B
This trial tests a new drug, AHB-137, in people with chronic hepatitis B who are already on a stable antiviral treatment. It aims to see if AHB-137 can help lower the virus further or improve outcomes.
Palo Alto, CaliforniaAges 18–65 - NCT06607055Recruiting
Immune markers in ICU patients with pneumonia
This study looks at how the immune system reacts in ICU patients on a ventilator who have pneumonia. By measuring immune markers, the researchers hope to better understand and predict complications like ventilator-associated pneumonia.
Aix-en-ProvenceAges 18 years+ - NCT05494346Recruiting
Seawater nasal spray with essential oils for blocked nose
This trial tests whether a seawater nasal spray (with essential oils) is safe and works well for people ages 12+ who have sudden (acute) cold- or allergy-related nasal blockage. You may be able to join if you can use the spray as instructed and complete simple monitoring and questionnaires.
Blainville-sur-OrneAges 12 years+ - NCT06381661RecruitingPhase 2
Personalized treatment for sepsis in children and adults
This trial is testing several different treatments to find the best one for each person with sepsis. It looks at specific 'treatable traits' like inflammation, blood clotting problems, or immune system issues to match you with the right therapy. The goal is to improve recovery and survival.
DijonAges 9 months+ - NCT07179575RecruitingPhase 1/Phase 2
Study of LW231 for people with chronic hepatitis B
This trial tests a new drug, LW231, in people with chronic hepatitis B. It aims to see if the drug can reduce the amount of virus and surface antigen in your blood, and if it is safe for you.
Hangzhou, ZhejiangAges 18–60 - NCT01386437Recruiting
Study immune problems and fungal infections
This study looks at how immune system problems relate to fungal infections, using medical records and lab tests on blood and tissue. It may help researchers understand the cause of these infections—especially for people with inherited immune conditions—and improve future care.
Bethesda, MarylandAges 1 day–99 years - NCT01168271Recruiting
Study malaria risk factors in pregnancy and young children
This study looks at why some people get malaria during pregnancy, and how young children’s bodies respond early in life. It may help researchers understand who is more likely to get malaria and why, which could guide future prevention and care.
BamakoAges 1 day–45 years - NCT07218211RecruitingPhase 4
Injectable PrEP study for Latine transgender women and gay men
This study offers a long-acting injectable form of PrEP (lenacapavir) to prevent HIV in Latine transgender women and gay men in the South. It aims to make HIV prevention easier by providing a shot instead of a daily pill.
Durham, North CarolinaAges 18 years+ - NCT07213258Recruiting
HIV and meth prevention study for HIV-negative men
This study tests a smartphone program to help HIV-negative men who have sex with men reduce meth use and improve PrEP adherence. It explores whether combining support for both behaviors is more effective than addressing them separately.
San Francisco, CaliforniaAges 18–40 - NCT05281471RecruitingPhase 3
Tested drug for platinum-resistant ovarian cancer with bevacizumab
This Phase 3 trial tests a treatment made of an investigational gene-based drug plus standard “platinum” chemotherapy and bevacizumab, compared with standard chemotherapy and bevacizumab. It’s for ovarian/fallopian tube/primary peritoneal cancers that have not responded to platinum chemotherapy or came back quickly.
Mobile, AlabamaAges 18 years+
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 4,171 recruiting infectious disease studies from the U.S. registry right now, out of 7,019 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.