Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,218 recruiting studies in this area right now.
By phase
- Not applicable2,751
- Phase 2121
- Phase 4117
- Phase 186
- Phase 384
- Phase 1/Phase 237
- Phase 2/Phase 322
Top conditions
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Spinal Cord Injury100
- Trauma60
- Stroke56
- Anterior Cruciate Ligament Injuries44
- Amputation43
- Mild Traumatic Brain Injury41
- Hip Fractures40
- Rotator Cuff Tears40
- Radiotherapy Side Effect36
- Spinal Cord Injuries (SCI)35
- Carpal Tunnel Syndrome34
- Burns31
- Anterior Cruciate Ligament Rupture30
- Breast Cancer29
- Cardiotoxicity29
- Carpal Tunnel Syndrome (CTS)25
Leading sponsors
- VA Office of Research and Development37
- Cairo University36
- Riphah International University32
- Kessler Foundation21
- University of Miami21
- Johns Hopkins University20
- Sohag University19
- Mayo Clinic18
- Peking University Third Hospital18
- University of Texas Southwestern Medical Center18
Where studies are running
- California168
- Texas101
- New York85
- Florida80
- Illinois57
- Massachusetts57
- Pennsylvania52
- Ohio51
- Minnesota46
- Maryland42
Recruiting studies3,218 total
- NCT05741411Recruiting
Text-and-phone support after concussion for teens
This study tests whether a phone-based (mHealth) handoff and follow-up can help teens after a concussion, especially those at higher risk of long-lasting symptoms. It uses smartphone check-ins and coordination between emergency and specialty care.
Philadelphia, PennsylvaniaAges 13–18 - NCT05741788Recruiting
Telefitting spinal cord stimulation for chronic pain
This study checks a “remote fitting” process to set up spinal cord stimulation for people with high levels of pain. You may be a fit if you are planning a stimulation trial and have severe pain right now.
Minneapolis, MinnesotaAges 22 years+ - NCT05742776Recruiting
Ultrasound and sleep quality check in carpal tunnel
This trial studies whether ultrasound exam findings match how well you sleep if you have carpal tunnel syndrome. It may help doctors better understand which ultrasound results go along with worse sleep and symptoms.
Afyonkarahisar, Afyonkarahi̇sarAges 20–80 - NCT05747079Recruiting
Early versus delayed surgery after a new ACL tear
This study compares immediate surgery versus waiting a short time for people with a new ACL injury. It aims to see which timing leads to better recovery and knee function.
LeuvenAges 16 years+ - NCT05751863Recruiting
Sedation-first vs usual care in ventilated trauma patients
This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.
Long Beach, CaliforniaAges 18 years+ - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT05754632Recruiting
Blood flow restriction exercises after ACL surgery in teens
This trial tests whether a special type of exercise that uses a cuff (blood flow restriction training, or BFRT) can help teens recover after ACL reconstruction. It’s designed to see if adding BFRT to standard rehab improves strength and return to sport.
Farmington, ConnecticutAges 12–18 - NCT05756894Recruiting
Stimulation therapy to improve breathing after spinal cord injury
This trial studies a neurostimulation approach to help breathing problems after a spinal cord injury. You may be able to join if you have a certain type and level of spinal cord injury and breathing weakness, and you can safely attend study visits with caregiver support.
Chicago, IllinoisAges 18–85 - NCT05762900RecruitingPhase 2
Shorter breast radiation after surgery for low-risk breast cancer
This Phase 2 trial tests a shorter, focused radiation treatment after breast surgery, either alone or with an extra targeted boost. It’s for people with low-risk breast cancer and no spread to distant organs, aiming to keep results while reducing treatment time and side effects.
BeijingAges 35 years+ - NCT05762796Recruiting
Brain scan and stimulation study for kids with mild concussion
This study tests whether a brain “stimulation” approach, paired with brain imaging (MRI), can help children who still have symptoms after a mild concussion. There is also a comparison group of children without concussion history.
Buffalo, New YorkAges 10–15 - NCT05766670RecruitingPhase 3
Calcium and antibiotic placed inside tibia nail for open fractures
This Phase 3 study tests whether a calcium/antibiotic “depot” released from an intramedullary nail can lower infection risk in certain open tibia fractures. It may help by delivering antibiotics right at the fracture area while the nail fixes the bone.
Los Angeles, CaliforniaAges 18 years+ - NCT05765929Recruiting
X-ray tests for deciding how to treat certain ankle fractures
This study uses special standing (weightbearing) ankle X-rays to see whether your ankle fracture is stable, to help guide treatment decisions. It may help doctors choose safer, more appropriate care for specific ankle fracture types.
Sarpsborg, Østfold fylkeAges 18–75 - NCT05769114Recruiting
Surgery vs non-surgery for a specific back fracture
This study compares surgery and non-surgical care for an acute burst fracture in the middle-to-lower back. The goal is to see which approach works better for healing and recovery.
BernAges 18–70 - NCT05775965RecruitingPhase 2
Aspirin plus rivaroxaban to prevent clots after hip fracture surgery
This trial studies which pill regimen helps prevent dangerous blood clots after hip fracture surgery. You might be eligible if you’re 50 or older and can start treatment soon after your injury.
Calgary, AlbertaAges 50 years+ - NCT05776030Recruiting
Test of different-speed ergonomic wheelchairs for daily users
This study tests a wheelchair design that can better match how you move and sit while using a manual wheelchair every day. You may be able to try different wheelchair setups if you meet the safety, seating, and body-size requirements.
Minneapolis, MinnesotaAges 18 years+ - NCT05780619Recruiting
Check a brain blood-flow test after carotid artery narrowing
This study tests how well a noninvasive ultrasound measurement (the Resistance Index) can show how well blood vessels in the brain respond to a medication. It may help doctors better assess brain blood-flow health in people with certain carotid artery blockages.
NîmesAges 18 years+ - NCT05782244RecruitingPhase 2
Sildenafil trial for long-term brain blood-flow problems after TBI
This Phase 2 study tests whether sildenafil (a medication better known for erectile function) can improve long-term symptoms and brain blood-flow issues after a past traumatic brain injury (TBI). It may help by improving blood vessel function in the brain and possibly reducing persistent post-concussion symptoms.
Philadelphia, PennsylvaniaAges 18–70 - NCT05783245Recruiting
Cooling therapy to reduce pain after open carpal tunnel surgery
This trial studies whether cooling (cold therapy) can lessen pain after open carpal tunnel release surgery. If you’re having this surgery, your answers to questionnaires and your current pain-medication status will determine whether you can join.
Chicago, IllinoisAges 18 years+ - NCT05785000Recruiting
Rehab program for long-lasting concussion symptoms
This trial tests a rehabilitation approach for people with post-concussion syndrome (ongoing symptoms after a mild head injury). It may help by guiding safer, structured recovery—especially through exercise—if it fits your situation and you can participate.
Copenhagen, Region of Greater CopenhagenAges 18–70 - NCT05785533Recruiting
Mobile app for recovery after recent ankle sprains
This trial tests whether a smartphone “recovery guidance” app can help children and young adults heal after a recent ankle inversion injury. It may help with home recovery steps and decision-making during the first days after injury.
London, OntarioAges 12–30 - NCT05786742Recruiting
Radiation plan test for early prostate cancer with a boost
This trial tests a more concentrated radiation schedule for early-stage prostate cancer, using an extra high-dose “boost” delivered from inside the body. It may help by treating the prostate more precisely while aiming to keep side effects manageable.
QuébecAges 18–95 - NCT05788861Recruiting
Study for children with severe strep skin or bloodstream infection
This trial is for people under 18 who have a confirmed invasive Group A strep infection, meaning strep bacteria found in places that are normally sterile (like the blood or deep tissues). It tests whether a specific study approach can help improve outcomes for children with these serious infections.
CréteilAges 1 day–17 years - NCT05792189Recruiting
Knee fracture surgery: plates vs knee replacement for older adults
This trial compares two ways to treat certain lower-thigh (distal femur) fractures near the knee: using plates/screws or doing a knee replacement. It aims to see which option works better for recovery and long-term outcomes.
Gainesville, FloridaAges 55–100 - NCT05795686Recruiting
Study of the AVanCer day-center support program for patients
This study looks at how a day-center support program (AVanCer) affects patients and their caregivers. If you join, you may complete questionnaires and help researchers understand your experiences through assessments in French.
BronAges 18 years+
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,218 recruiting trauma studies from the U.S. registry right now, out of 5,144 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.