Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,016 recruiting studies in this area right now.
By phase
- Not applicable2,561
- Phase 2123
- Phase 4112
- Phase 382
- Phase 182
- Phase 1/Phase 234
- Phase 2/Phase 322
Top conditions
- Traumatic Brain Injury151
- Spinal Cord Injuries142
- Spinal Cord Injury105
- Stroke64
- Trauma51
- Mild Traumatic Brain Injury40
- Amputation38
- Anterior Cruciate Ligament Injuries37
- Radiotherapy Side Effect37
- Hip Fractures36
- Rotator Cuff Tears35
- Spinal Cord Injuries (SCI)34
- Burns28
- Carpal Tunnel Syndrome28
- Anterior Cruciate Ligament Rupture27
- Cardiotoxicity26
- Carpal Tunnel Syndrome (CTS)26
- Breast Cancer25
Leading sponsors
- VA Office of Research and Development34
- Cairo University22
- Kessler Foundation20
- Johns Hopkins University19
- University of Miami19
- Zimmer Biomet19
- University of Florida18
- University of British Columbia17
- Mayo Clinic16
- Riphah International University16
Where studies are running
- California159
- Texas91
- Florida79
- New York78
- Illinois57
- Massachusetts55
- Pennsylvania51
- Minnesota45
- Ohio43
- Colorado41
Recruiting studies3,016 total
- NCT06443645Recruiting
Protecting the heart during breast cancer treatment
This trial tests whether a diabetes medicine (SGLT2 inhibitor) can prevent heart damage caused by a common chemotherapy drug (anthracycline) in people with early-stage breast cancer. If you are newly diagnosed and about to start chemotherapy or have surgery, this study may be for you.
StrasbourgAges 18 years+ - NCT06447948Recruiting
Keeping active after fall prevention classes
This study tests a program to help older adults keep exercising after finishing a fall prevention class. It aims to see if the program is practical and helps people stay steady and active.
Newcastle upon Tyne, Tyne and WearAges Any age - NCT06455085Recruiting
Preventing future fractures after a bone break
This study aims to help adults over 50 who had a recent bone fracture (from a minor fall) get better follow-up care to prevent future fractures. You will work with a nurse or coordinator to connect with your primary care doctor and learn about bone health options.
Birmingham, AlabamaAges 50 years+ - NCT06449742Recruiting
AI to find spine fractures on CT scans
This study is testing whether an artificial intelligence program can find broken bones in the spine (vertebral fractures) by looking at CT scans of the chest or abdomen. The goal is to see if AI can help doctors spot these fractures more easily, which could lead to earlier treatment.
Milan, ItalyAges 50 years+ - NCT06443281Recruiting
Understanding pain after spinal cord injury or nerve damage
This study is looking at how people with spinal cord injuries or peripheral neuropathy (nerve damage outside the spine) experience pain. The goal is to better understand the different types of pain, which could help doctors create more personalized treatments in the future.
Zurich, Canton of ZurichAges 18–80 - NCT06452186Recruiting
Study of a new leg prosthetic controller for improved balance
This study tests a new prosthetic leg controller that helps people with below-knee amputations walk more steadily and with better balance. You may be eligible if you have used a prosthetic leg for at least a year and are comfortable walking in the community.
Raleigh, North CarolinaAges 18–99 - NCT06453447Recruiting
Prednisone to prevent CRPS after wrist fracture surgery
This trial tests whether a short course of the steroid prednisone can prevent or reduce complex regional pain syndrome (CRPS) after wrist surgery. It is for people who had a broken wrist fixed with a plate and screws and have a higher chance of developing CRPS.
Vancouver, British ColumbiaAges 19 years+ - NCT06450678Recruiting
Can a physiotherapy test predict breathing tube removal success?
This study checks if a quick physical therapy exam can predict whether a person will need the breathing machine again after it is removed. It is for adults who have been on a ventilator for more than two days and have already shown they can breathe on their own for a short time.
ParisAges 18 years+ - NCT06455137Recruiting
Spinal cord stimulation for spinal cord injury recovery
This trial tests whether electrical stimulation of the spinal cord can improve movement and muscle control in people with spinal cord injury. If you've had a spinal cord injury for more than a year and are between 20-70 years old, this might help improve leg function and walking.
Hualien CityAges 20–70 - NCT06450392RecruitingPhase 4
Tranexamic acid for less swelling and bruising after eye socket surgery
This study tests whether giving tranexamic acid (a medicine that helps blood clot) locally or through an IV can reduce swelling and bruising after eye socket surgery.
The Bronx, New YorkAges 18 years+ - NCT06452485Recruiting
Re-irradiation with or without hyperthermia, or surgery only for recurrent breast cancer
This trial compares three treatment options for breast cancer that has come back in the chest or lymph nodes after previous radiation. It looks at adding hyperthermia (heating the tumor area) to re-irradiation, versus just re-irradiation or surgery alone, to see which offers better quality of life and survival with fewer side effects.
AmsterdamAges 18 years+ - NCT06452147Recruiting
Anesthesia types for preventing confusion after hip surgery in older adults
This study looks at different ways to give anesthesia during hip surgery to help older patients think and remember better afterward. It may help prevent confusion or memory problems that sometimes happen after surgery.
Dongyang, ZhejiangAges 65 years+ - NCT06454669RecruitingPhase 2
Dronabinol added to opioids for chronic low back pain
This trial tests whether adding dronabinol (a prescription medication derived from cannabis) to your current opioid pain treatment can help reduce chronic low back pain more effectively. It is for people who have had persistent low back pain for at least 3 months and are already on a stable opioid regimen.
Houston, TexasAges 18–64 - NCT05476263Recruiting
Negative pressure wound therapy for esophagus or rectum
This trial studies whether a device called Suprasorb CNPendo helps healing of certain full-thickness (through-and-through) injuries or wounds in the esophagus or rectum. It may be an option if your medical team is already considering negative pressure wound therapy for these specific problems.
BerlinAges 18 years+ - NCT05865327Recruiting
Nerve freezing for rib-fracture pain using ultrasound guidance
This trial tests whether freezing a specific nerve (a “cryoneurolysis” treatment) through a catheter can better control pain from traumatic rib fractures. It’s offered to adults who have rib fractures soon after hospital admission and can use a pain control method called patient-controlled regional analgesia.
Toronto, OntarioAges 18–100 - NCT06055257RecruitingPhase 3
Combination therapy for jaw bone damage after radiation
This trial tests a combination of hyperbaric oxygen therapy and a medication called PENTOCLO to treat osteoradionecrosis (bone damage) in the jaw after radiation treatment for cancer. It may help heal the exposed bone.
Toronto, OntarioAges Any age - NCT04459806Recruiting
Study dose timing to improve care for brain injury
This trial studies how to time medication or treatment doses when a person has serious brain injury, using measurements from a pressure monitor in the skull. It may help doctors manage brain swelling and pressure more effectively.
Monza, MBAges 18–80 - NCT06210620Recruiting
Prosthetic outcome registry for lower limb loss
This study is gathering information from people with lower limb loss. It aims to understand how different prosthetic devices work in real life, which can help improve future devices.
Irvine, CaliforniaAges 18 years+ - NCT06425627Recruiting
Spinal vs general anesthesia for hip fracture surgery in older adults
This study compares two types of anesthesia—spinal (awake, lower body numb) versus general (completely asleep)—for people 65 and older having hip fracture surgery. The goal is to see which is better for preventing lung complications after surgery.
Wuhan, HubeiAges 65 years+ - NCT06429501RecruitingPhase 2
Numbing medicine for facial fracture surgery
This study tests numbing medicine (local anesthetic) given during surgery for broken facial bones, like the jaw or cheekbones. The goal is to see how well it works and if it helps recovery.
St Louis, MissouriAges 18 years+ - NCT06435494Enrolling by invitation
Using patient reports to improve shoulder care across clinics
This study tests whether asking patients about their shoulder symptoms using a phone or computer app can help doctors and therapists work together to improve care. It is for adults with shoulder pain that started without a sudden injury.
Gentofte Municipality, HellerupAges 18–120 - NCT06438640Recruiting
My Anesthesia Choice for Hip Fracture Surgery
This trial tests a new way to help you and your doctor talk about anesthesia options before your hip fracture surgery. The goal is to see if this approach improves your experience and recovery.
Gainesville, FloridaAges 50 years+ - NCT06434272Recruiting
Blood flow restriction exercise after Achilles tendon rupture
This study tests whether adding blood flow restriction (using a special cuff) to standard rehabilitation exercises can help people with a torn Achilles tendon recover better. It might be an option if you recently ruptured your Achilles and started treatment within 72 hours.
Aarhus N, DenmarkAges 18 years+ - NCT06423378Enrolling by invitationPhase 2
Kneebar implant for knee pain and bone marrow lesion
This trial tests a new type of implant (a fiber-reinforced kneebar) for people with knee pain caused by a bone marrow lesion (BML) and osteoarthritis. The goal is to see if it helps relieve pain and improve knee function.
Nashville, TennesseeAges 18–75
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,016 recruiting trauma studies from the U.S. registry right now, out of 4,936 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.