Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,386 recruiting studies in this area right now.
By phase
- Not applicable2,716
- Phase 2569
- Phase 1363
- Phase 3265
- Phase 1/Phase 2227
- Phase 4191
- Phase 2/Phase 355
Top conditions
- Prostate Cancer644
- Bladder Cancer186
- Acute Kidney Injury134
- Chronic Kidney Diseases122
- Chronic Kidney Disease107
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence60
- Kidney Cancer59
- Colorectal Cancer57
- Ovarian Cancer56
- Lung Cancer51
- Cancer48
- Lupus Nephritis48
- Melanoma47
- Head and Neck Cancer46
- Metastatic Prostate Cancer46
- Hypertension45
Leading sponsors
- Mayo Clinic64
- National Cancer Institute (NCI)48
- Peking University First Hospital39
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong33
- Novartis Pharmaceuticals33
- IRCCS Azienda Ospedaliero-Universitaria di Bologna29
- Memorial Sloan Kettering Cancer Center29
- AstraZeneca28
- Assistance Publique - Hôpitaux de Paris27
Where studies are running
- California356
- Arizona109
- Alabama107
- New York96
- Florida93
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Minnesota50
Recruiting studies4,386 total
- NCT06983028RecruitingPhase 2
Testing atacicept for multiple kidney diseases
This trial tests a medicine called atacicept in adults and children with several types of kidney disease. The goal is to see if it can reduce protein in the urine and help protect kidney function.
Brisbane, CaliforniaAges 2 years+ - NCT06990880RecruitingPhase 1/Phase 2
A study of a new drug for advanced prostate cancer
This study tests an experimental drug, alone or with other treatments, for men with advanced prostate cancer that has stopped responding to standard therapies. The goal is to see if it can shrink tumors or slow the disease.
Phoenix, ArizonaAges 18 years+ - NCT06989359RecruitingPhase 2
Study of ADX-038 for complement-related kidney disease
This trial tests an experimental drug called ADX-038 for people with certain types of kidney disease that are driven by the complement system (a part of the immune system). The study aims to see if ADX-038 can help slow down or improve kidney function.
Doral, FloridaAges 18 years+ - NCT06984679Recruiting
Physical function study for kids with cystic fibrosis
This trial compares physical abilities between children with cystic fibrosis and healthy children. It aims to find differences that could lead to better care and therapies.
IzmirAges 6–18 - NCT06986824RecruitingPhase 4
Pelvic wand massage in late pregnancy
This trial tests whether gently massaging the perineum with a special pelvic wand during late pregnancy can help prepare for birth. It is offered to people who plan to deliver at Beth Israel Deaconess Medical Center.
Boston, MassachusettsAges 18 years+ - NCT06987877Recruiting
Saline flushes to keep kidney tubes working
This study tests if flushing a kidney drainage tube with saline helps prevent blockages. It may help people who have a tube in their kidney and need it for at least 12 weeks.
Boston, MassachusettsAges 18–80 - NCT06987604Enrolling by invitation
Dialysis intensity for high ammonia in liver failure
This trial tests if a higher intensity of continuous dialysis (CRRT) better lowers ammonia levels in patients with liver failure. It aims to find the best approach to reduce brain complications from high ammonia.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06983730RecruitingEarly Phase 1
Vitamin B3 and Kidney Response to Exercise in Heat
This study tests how your kidneys respond to exercise in the heat, and whether taking vitamin B3 (niacin) changes that response. It might help protect the kidneys of people who work or exercise in hot conditions.
Boston, MassachusettsAges 18–45 - NCT06989320Recruiting
Oxalate production in calcium oxalate stone formers
This study looks at how the body makes oxalate (a natural substance that can form kidney stones) in people who have had calcium oxalate stones. You will eat a special diet and stop supplements for a short time to help researchers understand stone formation.
Birmingham, AlabamaAges 18–80 - NCT06986304Recruiting
Super-Resolution Ultrasound for Bladder Cancer
This study uses a special ultrasound technique to take detailed pictures of the tiny blood vessels around bladder cancer. The goal is to help doctors better understand the cancer before surgery to remove the bladder.
Durham, North CarolinaAges 18 years+ - NCT06990542RecruitingPhase 2
Focused radiation therapy for intermediate and high-risk prostate cancer
This trial tests a more precise radiation therapy that targets tumors seen on MRI or special scans, aiming to treat prostate cancer while reducing side effects. It is for men who have not had prostate surgery or previous radiation to the area.
La Jolla, CaliforniaAges 18 years+ - NCT06983210RecruitingPhase 2
Combination treatment for advanced bladder cancer
This trial tests a new drug combination for people with advanced bladder or urinary tract cancer that has not been treated before. The goal is to see if adding AM80 to standard chemotherapy and immunotherapy works better.
Nagoya, Aichi-kenAges 18–79 - NCT06983470Recruiting
Study on nerve responses during bladder device treatment
This trial tests how the body's nerve signals respond during a treatment for overactive bladder (OAB) that uses a device to stimulate a nerve near the tailbone. The goal is to understand how these nerve responses might predict treatment success.
Ann Arbor, MichiganAges 18 years+ - NCT06989593Recruiting
Storytelling study for parents of children with urogenital conditions
This study tests whether guided journaling (writing or dictating stories) can help parents cope and connect. It involves a 5-week journaling activity and one follow-up interview.
Boston, MassachusettsAges 18 years+ - NCT06986083RecruitingPhase 3
Testing changes in prostate biopsy and ablation care
This study looks at two ways to improve prostate procedures: 1) whether adding local anesthesia during a biopsy (while you’re already sedated) makes a difference, and 2) whether a standard care plan before and after focal gland ablation helps recovery compared to usual care.
Basking Ridge, New JerseyAges 18 years+ - NCT06990672Enrolling by invitation
WeChat therapy to help kidney stone patients drink more water
This study tests if a WeChat-based digital program can help people who've had kidney stone surgery increase their daily fluid intake to prevent new stones. You might qualify if you drink less than 2.5 liters of fluid per day and use WeChat regularly.
Shenzhen, GuangdongAges 18 years+ - NCT06987084Enrolling by invitationEarly Phase 1
Bryophyllum Tea for Kidney Stone Prevention
This study tests whether a special tea made from the Bryophyllum pinnatum plant can help people who get calcium kidney stones. If you've had a stone or high calcium in your urine, this trial may offer a natural option to try.
Montreal, QuebecAges 18–70 - NCT06987045Recruiting
PSA levels in trans and non-binary people with a prostate
This study aims to find normal PSA (prostate-specific antigen) levels for trans and non-binary people who have a prostate and are on hormone therapy or have had certain surgeries. Your participation could help improve future cancer screening guidelines for your community.
LondonAges 40–100 - NCT05997992Recruiting
Electroacupuncture for overactive bladder in women
This study tests whether adding electroacupuncture (a type of acupuncture with mild electrical pulses) to usual care can help control overactive bladder symptoms in women. If you are a woman aged 20–80 with overactive bladder and haven't tried certain treatments before, you may be eligible.
New Taipei CityAges 20–80 - NCT05577689Recruiting
New treatment target study for metastatic prostate cancer
This trial studies a new therapy target for people with prostate cancer that has spread to other parts of the body. You may be a candidate if you can provide a cancer tissue sample and are able to consent to the study.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05740956RecruitingPhase 1
Drug study for cancers with HRR gene or HRD changes
This Phase 1 study tests HS-10502 in people with advanced solid tumors that have certain DNA repair problems (HRR or HRD). It may help by finding a safe dose and seeing whether the drug can shrink tumors in cancers that have specific genetic features.
Beijing, Beijing MunicipalityAges 18–75 - NCT05326620Recruiting
Renal cancer patients join a Dutch research kidney study
This study enrolls people newly diagnosed with kidney cancer (including when it has spread) to help build research resources for future kidney cancer care. If you qualify, your information may be used to better understand outcomes and improve treatments.
Amsterdam, North HollandAges 18 years+ - NCT06972615RecruitingPhase 2
Bladder chemo plus pembrolizumab for BCG-treated cancer
This trial tests a combination of chemotherapy placed directly into the bladder and an immunotherapy drug called pembrolizumab (given through a vein) for people with high-risk bladder cancer that has not completely responded to or has returned after BCG treatment.
CABAAges 18 years+ - NCT06975787RecruitingPhase 1
A New Bispecific Antibody for Lupus Nephritis
This trial is testing a new type of medicine called a 'bispecific antibody' for people whose lupus nephritis has not responded to standard treatments or keeps coming back. The goal is to find a safe dose that might better control the kidney inflammation.
San Francisco, CaliforniaAges 18–60
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,386 recruiting nephrology & urology studies from the U.S. registry right now, out of 6,845 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.