Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,504 recruiting studies in this area right now.
By phase
- Not applicable2,821
- Phase 2564
- Phase 1366
- Phase 3271
- Phase 1/Phase 2230
- Phase 4194
- Phase 2/Phase 358
Top conditions
- Prostate Cancer651
- Bladder Cancer191
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Breast Cancer104
- Chronic Kidney Disease104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer55
- Lupus Nephritis54
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Prostate Cancer (Adenocarcinoma)46
- Renal Cancer46
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals35
- Chinese University of Hong Kong34
- AstraZeneca30
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama112
- Arizona103
- Florida97
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,504 total
- NCT06111781RecruitingPhase 2
Hormone Therapy and Radiation for Intermediate Risk Prostate Cancer
This study tests whether a combination of short-term hormone therapy (relugolix) and focused radiation (SBRT) can treat a certain type of prostate cancer that is considered favorable but has a higher genetic risk. It aims to find a less intense treatment that still works well.
New Haven, ConnecticutAges 18 years+ - NCT07710157RecruitingPhase 2
Obinutuzumab for first episode of minimal change disease
This trial tests if obinutuzumab, a targeted therapy, can safely and effectively treat adults with their first episode of minimal change disease (MCD), a kidney condition causing protein leakage. Participants will receive the drug to see if it reduces protein in urine and improves symptoms.
GrazAges 18 years+ - NCT06039371RecruitingPhase 2
High dose testosterone during chemo for advanced prostate cancer
This trial tests if adding high doses of testosterone to standard chemotherapy (etoposide and carboplatin) can make the chemo work better in men whose prostate cancer has stopped responding to other treatments. It aims to see if this approach can shrink tumors or slow cancer growth.
Seattle, WashingtonAges 18 years+ - NCT07221825Recruiting
Radium-223 imaging study for men with prostate cancer
This study uses a special type of scan (quantitative SPECT) to measure how Radium-223 (Xofigo) works in your bones. It helps doctors better understand treatment for prostate cancer that has spread to the bones.
St Louis, MissouriAges 18 years+ - NCT06520345RecruitingPhase 3
A new treatment for advanced prostate cancer that has stopped responding to hormone therapy
This trial tests a new radioactive drug (177Lu-TLX591) plus standard care against standard care alone for men with metastatic castration-resistant prostate cancer that has progressed on an androgen receptor pathway inhibitor. The goal is to see if this targeted radiation can help control the cancer.
Orange, CaliforniaAges 18 years+ - NCT06378866RecruitingPhase 2
Radiation with hormone therapy timing for prostate cancer
This study is testing whether using focused radiation beams (SBRT) right away or later, along with hormone therapy, can help control prostate cancer that has returned in a few spots outside the pelvis. The goal is to find the best timing for combining radiation and hormone treatment.
Phoenix, ArizonaAges 18 years+ - NCT06500702RecruitingPhase 2
Study of three drugs for FSGS or minimal change disease
This study tests three experimental drugs (frexalimab, brivekimig, and rilzabrutinib) for people ages 16 to 75 with a type of kidney disease called primary FSGS or minimal change disease. The goal is to see if these drugs can reduce protein in your urine and help protect your kidneys.
Birmingham, AlabamaAges 16–75 - NCT06814496RecruitingPhase 1/Phase 2
Radiation and immunotherapy combo for DLL3-positive cancers
This trial combines radiation with an immunotherapy drug called tarlatamab to treat cancers that make a protein called DLL3. The goal is to see if this combination works better than either treatment alone for people with certain types of lung cancer and other tumors that have not responded to prior therapy.
Tucson, ArizonaAges 18–99 - NCT07694752Recruiting
MRI study of prostate and urinary sphincter
This study uses special MRI scans to look at the muscle ring that controls urination and the base of the prostate. It may help doctors understand how these areas change with conditions like enlarged prostate or prostate cancer treatment.
Taizhou, JiangsuAges 15–90 - NCT07714694Recruiting
Testing a new intermittent catheter for men
This study asks men who use a specific type of catheter (hydrophilic, size 14 French, 40 cm long) at least three times a day to try a new catheter and share their experience through online questionnaires. The goal is to see how well the new catheter works for daily use.
Libertyville, IllinoisAges 22 years+ - NCT07713680Recruiting
Predicting beta-2 microglobulin rebound after dialysis
This study looks at how a protein called beta-2 microglobulin (β2M) changes after your dialysis session. It aims to better understand this protein's levels to help manage your treatment.
StevenageAges 18 years+ - NCT07424287RecruitingPhase 3
New drug plus BCG vs chemo for BCG-resistant bladder cancer
This trial tests a new combination treatment (SHR-1501 plus BCG) compared to standard chemotherapy for people with bladder cancer that hasn't responded to BCG. The goal is to see if this combination works better at controlling the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04163614Recruiting
Testing blood pressure patterns and fluid removal during dialysis
This study looks at how blood pressure changes during hemodialysis and how much fluid is removed, to see what approach works best for controlling blood pressure. It may help dialysis patients whose blood pressure is often high before or after treatment.
Dallas, TexasAges 18 years+ - NCT05106387Recruiting
Study follow-up for people who had a kidney transplant
This study follows adults who previously received vonsetamig in an earlier study and then got a kidney transplant while enrolled. It mainly looks at what happens after the transplant and helps doctors understand outcomes over time.
Los Angeles, CaliforniaAges 18–70 - NCT04430426Enrolling by invitation
Study for kidney stone patients with an AGXT gene change
This study looks at people age 18+ who have a history of calcium oxalate kidney stones and who have a specific AGXT gene change found on genetic testing. It involves following a controlled diet for five days, which may help researchers understand how diet affects kidney stones in this group.
Birmingham, AlabamaAges 18 years+ - NCT06326905Recruiting
Transplant help for kidney waitlist patients with barriers
This study helps people on the deceased donor kidney waitlist who have had setbacks like health issues, lack of support, or low income. It offers extra support to help you get ready for transplant.
Baltimore, MarylandAges 18–99 - NCT07710807Recruiting
Comparing two prostate biopsy methods
This trial compares two ways to take a prostate biopsy (through the rectum or through the skin between the scrotum and anus) to see which is more accurate. Men with suspicious MRI findings (PI-RADS 3, 4, or 5) who haven't had prostate cancer before may be eligible.
Ankara, YenimahalleAges 50–75 - NCT07710183Recruiting
Pumpkin seed oil for hemodialysis patients
This study tests if pumpkin seed oil, a natural supplement, can improve health in people on long-term dialysis. It may help with inflammation and nutrition without using prescription drugs.
Baghdad, KarkhAges 18 years+ - NCT07712679Recruiting
Studying Kidney Scarring with FAPI PET/CT
This study uses a special PET/CT scan to look for scarring in the kidneys. The goal is to see if the scan can detect kidney fibrosis better than current methods.
Vienna, State of ViennaAges 18 years+ - NCT07419828RecruitingPhase 3
Study of HRS-1780 for chronic kidney disease
This trial tests an investigational drug called HRS-1780 in people with chronic kidney disease. It aims to see if the drug can help slow kidney decline and is safe to use.
Nanjing, JiangsuAges 18–80 - NCT06529822RecruitingPhase 1
Personalized cancer vaccine for solid tumors with MRD
This trial tests a personalized cancer vaccine for people with certain cancers (bladder, stomach/esophagus, melanoma, or lung) who have no visible cancer after surgery but still have tiny bits of cancer DNA in their blood (called MRD). The vaccine is designed to train your immune system to attack any remaining cancer cells.
Orlando, FloridaAges 18 years+ - NCT04857502RecruitingEarly Phase 1
Tracking prostate cancer spread before lymph node surgery
This early study uses a special imaging tracer to show where prostate cancer has spread in the pelvic lymph nodes. It may help doctors better understand how well certain scans guide surgical removal of affected lymph nodes.
Los Angeles, CaliforniaAges Any age - NCT06067269RecruitingPhase 2
Hormone therapy and precise radiation for intermediate-risk prostate cancer
This trial tests whether giving a short course of hormone therapy (apalutamide) along with targeted, high-dose radiation (SBRT) is safe and effective for men with a specific type of intermediate-risk prostate cancer. You may benefit if you fit the exact risk and test criteria.
Los Angeles, CaliforniaAges 18 years+ - NCT05719220Recruiting
Group pelvic floor training before HoLEP surgery
This trial tests whether group pelvic floor exercises done before HoLEP surgery can improve recovery and urinary symptoms in men with an enlarged prostate. It may help some people feel better sooner by strengthening the muscles that control urination.
San Francisco, CaliforniaAges 50–90
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,504 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,162 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Skin
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.