Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,502 recruiting studies in this area right now.
By phase
- Not applicable2,817
- Phase 2566
- Phase 1365
- Phase 3272
- Phase 1/Phase 2230
- Phase 4194
- Phase 2/Phase 358
Top conditions
- Prostate Cancer651
- Bladder Cancer191
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Chronic Kidney Disease105
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer55
- Lupus Nephritis54
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Prostate Cancer (Adenocarcinoma)46
- Head and Neck Cancer45
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals35
- Chinese University of Hong Kong34
- AstraZeneca31
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California349
- Alabama112
- Arizona104
- Florida96
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,502 total
- NCT07780188Recruiting
Lean beef in a healthy meal plan for teens with PCOS
This study tests whether adding lean beef to a healthy meal plan can help teens with PCOS improve their health. You'll follow a special diet and wear a small monitor to track your blood sugar, and the study may help you feel better and manage your condition.
College Station, TexasAges 11–17 - NCT06844383RecruitingPhase 2
Talazoparib with or without enzalutamide for prostate cancer after prior treatment
This study tests a drug called talazoparib, either alone or combined with enzalutamide, in people with prostate cancer that has spread and has a specific genetic change. The goal is to see if this treatment can help control the cancer after previous therapies have stopped working.
Duarte, CaliforniaAges 18 years+ - NCT07773090Recruiting
Stenting before mini-keyhole kidney stone surgery
This trial is looking at whether placing a small tube (stent) in the ureter before a type of keyhole surgery for kidney stones helps with outcomes like pain and success of the procedure. It aims to see if this pre-treatment makes the surgery easier, potentially reducing complications and improving stone removal.
CairoAges 18–70 - NCT07623369RecruitingPhase 1
First-in-Human Study of HH160 for Advanced Solid Tumors
This is an early-stage trial testing a new drug called HH160 in patients with advanced cancer (solid tumors). Researchers want to find the right dose and learn how well it works and what side effects it causes.
Waratah, New South WalesAges 18–75 - NCT06863272RecruitingPhase 1/Phase 2
Study of ifinatamab deruxtecan for advanced prostate cancer
This trial tests a new drug, ifinatamab deruxtecan, either alone or in combination with other treatments, for men with metastatic castrate-resistant prostate cancer that has worsened despite hormone therapy. It aims to see if this approach can help shrink or slow the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT07480356RecruitingPhase 3
Testing a new bladder cancer treatment (TARA-002) vs standard chemo
This trial compares a new medicine called TARA-002, given directly into the bladder, to the doctor's choice of standard chemotherapy. It is for people with a high-grade, non-muscle invasive bladder cancer that has not been treated with BCG or has not had BCG recently.
Queen Creek, ArizonaAges 18 years+ - NCT07265947RecruitingPhase 2
Testing dabogratinib for low-grade upper tract bladder cancer
This trial tests a new targeted therapy pill, dabogratinib, for people with low-grade upper tract urothelial carcinoma (a type of cancer in the tubes that carry urine from kidneys to bladder). It may be an option if you have tumor tissue left after a biopsy and haven't had certain prior treatments.
Tampa, FloridaAges 18 years+ - NCT07454603Recruiting
Blood test for prostate cancer risk
This trial tests a new blood test to help decide if you need a prostate biopsy. It may help men with high PSA levels or an abnormal rectal exam avoid unnecessary procedures.
Branford, ConnecticutAges 45–80 - NCT05805371RecruitingPhase 1
PSCA CAR-T cells with or without radiation for prostate cancer
This Phase 1 study tests a prostate cancer treatment made of PSCA-targeted CAR-T cells, with or without radiation, to help control advanced prostate cancer. It aims to find a safe treatment approach and see how well it works in people whose cancer has PSCA.
Duarte, CaliforniaAges 18 years+ - NCT07218380RecruitingPhase 3
Study of Vepugratinib for advanced bladder or urinary tract cancer
This trial tests an experimental drug called Vepugratinib for people with advanced urinary tract cancer that has a specific change in the FGFR3 gene. It may be an option if you haven't had other treatments for advanced cancer and are looking for a new approach.
Huntsville, AlabamaAges 18 years+ - NCT07206056RecruitingPhase 1/Phase 2
Study of tulmimetostat and luxdegalutamide for advanced prostate cancer
This trial tests a new combination of two drugs for men whose prostate cancer has spread and is no longer controlled by hormone therapy. The study aims to see if this treatment can help shrink tumors or slow the disease.
Denver, ColoradoAges 18 years+ - NCT07005154RecruitingPhase 2
Study of ASP5541 for metastatic prostate cancer
This study tests an experimental drug called ASP5541 for men with metastatic prostate cancer (either hormone-sensitive or castration-resistant). It aims to see if the drug can slow cancer growth and improve outcomes when added to standard hormone therapy.
Huntsville, AlabamaAges 18 years+ - NCT06952803RecruitingPhase 3
Testing a new drug for men with BRCA-related prostate cancer
This trial tests whether adding a new drug (saruparib) to standard radiation and hormone therapy can help prevent prostate cancer from spreading to other parts of the body. It is for men with high-risk prostate cancer that has a BRCA gene mutation.
Phoenix, ArizonaAges 18 years+ - NCT07006831Recruiting
Blood study for kidney transplant patients
This study collects blood and leftover donor samples from kidney transplant recipients who need a biopsy. The goal is to improve monitoring after transplant.
San Diego, CaliforniaAges 18 years+ - NCT07532941RecruitingPhase 4
Stopping antibiotics early versus completing the full course
This study compares two ways of giving antibiotics to children: stopping when symptoms feel better versus finishing all the prescribed doses. Researchers want to see if stopping early is safe and works just as well, which could help reduce unnecessary antibiotic use.
Melbourne, VictoriaAges 1–17 - NCT07544667Recruiting
Poly-L-Lactic Acid Injections for Vaginal Tissue Support
This trial tests whether injections of a biocompatible filler (Poly-L-Lactic Acid, also called Sculptra) can help reduce bulging or heaviness in the vaginal area caused by pelvic organ prolapse. The filler is designed to strengthen vaginal tissue and may improve symptoms without surgery.
Durham, North CarolinaAges 21 years+ - NCT06872619Enrolling by invitation
Prostate Cancer Research Registry
This registry collects information from people with prostate cancer to help researchers better understand the disease and improve future treatments.
MünsterAges 45–100 - NCT07568509RecruitingEarly Phase 1
Oxytocin levels in children with pituitary disease
This study measures oxytocin (a natural hormone) levels in children who have pituitary gland problems. Researchers want to understand if children with certain pituitary conditions don't make enough oxytocin, which could help guide future treatments.
Boston, MassachusettsAges 7–21 - NCT06531824RecruitingPhase 3
Heart and kidney protection study for chronic kidney disease
This study tests a new medicine (BI 690517) combined with empagliflozin to see if it can help protect the heart and kidneys in people with chronic kidney disease. It may slow down kidney disease progression and reduce heart risks.
Huntsville, AlabamaAges 18 years+ - NCT07598396RecruitingPhase 2
Mosunetuzumab for systemic lupus erythematosus treatment
This study tests a new drug called mosunetuzumab in people with systemic lupus erythematosus (SLE), a disease where the immune system attacks the body's own tissues. The drug is designed to help control the immune response and reduce lupus symptoms, including kidney involvement if present.
Salvador, Estado de BahiaAges 18 years+ - NCT07553065RecruitingPhase 2
Bladder Treatment Study with NT 201 and Vibe System
This study tests a new bladder treatment called NT 201 combined with a device called the Vibe System for women with overactive bladder (frequent, urgent need to urinate). The treatment is injected directly into the bladder and may help reduce urgency and leaking.
Reno, NevadaAges 18–80 - NCT06945172Recruiting
Comparing quality of life after prostate removal vs. focal HIFU for prostate cancer
This study compares how two treatments—total prostate removal or focal HIFU (a targeted ultrasound therapy)—affect quality of life in men with favorable intermediate-risk prostate cancer who are sexually active. It aims to help patients choose the best option for their lifestyle.
Quint-FonsegrivesAges 40–75 - NCT07541287RecruitingPhase 2
JADE101 for IgA Nephropathy Kidney Disease
This study tests whether JADE101, a new medicine, can help slow kidney damage in people with IgA nephropathy (a type of kidney disease caused by immune system problems). You'll take it alongside your current blood pressure medications for about 48 weeks.
Chula Vista, CaliforniaAges 18–60 - NCT07107945RecruitingPhase 3
Study of empagliflozin for children with chronic kidney disease
This trial tests if empagliflozin, a daily pill, is safe and helps children ages 2–17 with chronic kidney disease (CKD). Your child may be eligible if they have reduced kidney function and elevated protein in their urine, and are already on stable kidney treatments.
Birmingham, AlabamaAges 2–17
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,502 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,145 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.