Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,505 recruiting studies in this area right now.
By phase
- Not applicable2,822
- Phase 2562
- Phase 1366
- Phase 3271
- Phase 1/Phase 2230
- Phase 4195
- Phase 2/Phase 359
Top conditions
- Prostate Cancer651
- Bladder Cancer192
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Breast Cancer105
- Chronic Kidney Disease104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer56
- Lupus Nephritis53
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Head and Neck Cancer46
- Prostate Cancer (Adenocarcinoma)46
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong34
- Novartis Pharmaceuticals34
- AstraZeneca29
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama111
- Arizona103
- Florida97
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,505 total
- NCT05753839Recruiting
Testing surgery plus immunotherapy for metastatic kidney cancer
This trial studies whether removing the kidney tumor (cytoreductive nephrectomy) before treatment can improve outcomes for people with metastatic clear-cell kidney cancer. All participants are expected to receive standard immunotherapy (nivolumab plus ipilimumab), and the study focuses on the role of surgery in the “immuno-oncology era.”
SeoulAges 18 years+ - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT05756569RecruitingPhase 2
Enfortumab plus pembrolizumab for advanced bladder cancer variants
This trial studies enfortumab vedotin plus pembrolizumab (immunotherapy) for people with advanced bladder cancer that has a “variant” or non-urothelial subtype. It aims to shrink tumors and improve outcomes when standard options have not worked or are no longer enough.
Atlanta, GeorgiaAges 18 years+ - NCT05757687Recruiting
Omega System for urinary symptoms from enlarged prostate
This trial studies a device called the Omega System to see if it is safe and effective for urinary problems caused by an enlarged prostate (BPH). You may be a better fit if you have moderate-to-severe symptoms and prostate measurements that match the study plan, and if you are scheduled for prostate surgery or need evaluation for BPH.
TbilisiAges 50 years+ - NCT05758077Recruiting
SeLective blood-filter trial for acute kidney injury in ICU
This trial tests a special device that filters parts of the blood to calm inflammation in people with severe acute kidney injury in the ICU. It may help improve recovery and reduce complications by “deactivating” certain immune cells.
Birmingham, AlabamaAges 18 years+ - NCT05759468RecruitingPhase 2
Add NAD to help protect kidneys in diabetes
This Phase 2 study tests whether adding NAD can improve kidney health in people with diabetes-related kidney disease. It is designed for people with certain urine lab results showing kidney stress, while keeping blood sugar and safety limits within range.
Boston, MassachusettsAges 30 years+ - NCT05761093Recruiting
Share your treatment preferences for metastatic prostate cancer
This study asks people with metastatic prostate cancer and their doctors about what benefits and risks matter most when choosing treatment. Your answers can help improve how treatment options are discussed in Hong Kong.
ShatinAges 18 years+ - NCT05761275Recruiting
Sexual quality of life after minimally invasive benign surgery
This study looks at how minimally invasive “vNOTES” surgery affects women’s sexual quality of life after a non-cancer (benign) gynecologic procedure. You might be eligible if you recently had this type of surgery and meet specific health, infection, and language requirements.
GenevaAges 18–70 - NCT05762198Recruiting
Rezūm vs TURP for blocked urine from enlarged prostate
This study compares two procedures—Rezūm (water vapor therapy) and TURP (a surgery)—for men whose urine blockage is not improving. The goal is to see which option works better and is safer for relieving urinary retention due to an enlarged prostate.
Hong KongAges 50–80 - NCT05765084RecruitingPhase 1/Phase 2
Atezolizumab plus WT1 vaccine with chemo for pleural mesothelioma
This trial studies a treatment plan that combines an immune drug (atezolizumab) and a personalized cancer vaccine (WT1/DC) with standard first-line chemotherapy for epithelioid malignant pleural mesothelioma that cannot be removed with surgery. It aims to improve control of the cancer by helping the immune system work alongside chemotherapy.
Edegem, AntwerpAges 18 years+ - NCT05765500RecruitingPhase 2
Relugolix vs leuprolide to improve prostate cancer quality of life
This Phase 2 study compares two medicines that lower testosterone—relugolix tablets versus leuprolide injections—to see which better improves quality of life. It’s for people with prostate cancer who are starting hormone treatment and have not used similar testosterone-lowering drugs before.
Boston, MassachusettsAges 18 years+ - NCT05766371RecruitingPhase 2
Pembrolizumab plus PSMA-targeted therapy for advanced prostate cancer
This Phase 2 trial tests whether adding pembrolizumab to a PSMA-targeted drug can better treat metastatic prostate cancer that has progressed despite hormone-blocking treatments. It may help some people by attacking PSMA-positive cancer spots seen on a special PET scan.
San Francisco, CaliforniaAges 18 years+ - NCT05767307Recruiting
MRI for suspected prostate cancer in Denmark
This study is enrolling adults who have prostate cancer concerns and are being sent for an MRI scan. It aims to improve evaluation of suspected prostate cancer, which may help doctors decide next steps more accurately.
Aarhus N, AarhusAges 18–99 - NCT05770037RecruitingPhase 2/Phase 3
Alectinib for ALK-positive cancers in teens and adults
This study tests whether alectinib can treat ALK-positive cancers in adults, teenagers, and children. It focuses on people whose cancer testing shows an ALK change, and who can start oral treatment and have a new tissue sample.
BelfastAges Any age - NCT05771168Recruiting
Surgery for men with stress urinary leakage
This study looks at men who are having surgery for stress urinary incontinence (urine leakage when coughing, sneezing, or exerting yourself) using devices like a sling or artificial urinary sphincter. It will follow how patients do after surgery using questionnaires, to understand benefits and experiences.
Roma, RomeAges 18 years+ - NCT05771597Recruiting
Home biofeedback to improve bowel and bladder control
This study tests whether doing guided “biofeedback” exercises at home can improve problems with constipation/blocked feeling, fecal leaks, and/or urine leaks. It focuses on retraining the muscles used for toileting to help you empty more normally and have fewer accidents.
Augusta, GeorgiaAges 18 years+ - NCT05773378Recruiting
Intravaginal device for urine leakage in female runners
This trial studies whether using a device placed inside the vagina can reduce urine leakage during running. It’s aimed at women who leak urine regularly while they run and are willing to keep running at their usual pace and schedule during the study.
Ottawa, OntarioAges 18 years+ - NCT05772637Recruiting
Testing bladder feeling in people with multiple sclerosis
This study checks how your bladder “sensation” works using bladder testing (including urodynamic testing) to better understand MS-related bladder problems. It may help researchers match bladder symptoms to what’s happening inside the bladder.
Paris, Choisir Une RégionAges 18–99 - NCT05772871RecruitingPhase 4
Prednisone plus herbal granules for children with nephrotic syndrome
This trial tests whether adding Huaiqihuang granules to prednisone can improve outcomes for children with primary, hormone-sensitive nephrotic syndrome. It also closely monitors safety to see if the combination causes fewer or more side effects than usual care.
Hefei, AnhuiAges 1.5 years–18 years - NCT05775042RecruitingPhase 2
CM338 for immunoglobulin A kidney disease
This Phase 2 study tests CM338 to see if it can help people with immunoglobulin A (IgA) nephropathy, a kidney condition. You may be able to join if you meet age, medication, and health criteria and can follow study safety rules.
Beijing, Beijing MunicipalityAges 18–75 - NCT05778552Recruiting
Home pelvic floor training follow-up for bladder and pelvic support issues
This study checks how well a home-based pelvic muscle training program works over the medium and long term for people with stress urine leakage and pelvic support problems. It may help you learn whether this at-home exercise plan improves bladder control and comfort over time.
TaipeiAges 18 years+ - NCT05779631Recruiting
MRI test to better stage suspected bladder cancer
This study uses a special MRI scan (mpMRI) to figure out how far suspected muscle-invasive bladder cancer has spread, using a new local staging approach. If the results are accurate, it may help doctors plan the most appropriate curative treatment sooner.
's-HertogenboschAges 18 years+ - NCT05781217RecruitingPhase 3
Short vs longer hormone therapy after salvage prostate radiation
This trial compares two lengths of hormone treatment (androgen deprivation therapy) given around “salvage” radiation after prostate surgery for rising PSA. It aims to see which schedule works best to control prostate cancer while keeping side effects manageable.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT05783908Recruiting
Self-guided breathing help during MRI-guided radiotherapy for moving tumors
This study tests whether a self-guidance approach for breathing can improve radiotherapy sessions when the tumor moves during breathing and is treated with an MRI-guided machine. It may help make treatments more accurate and easier to follow during each session.
Dijon, Côte d'OrAges 1.5 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,505 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,180 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.