Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,387 recruiting studies in this area right now.
By phase
- Not applicable2,710
- Phase 2569
- Phase 1367
- Phase 3266
- Phase 1/Phase 2227
- Phase 4192
- Phase 2/Phase 356
Top conditions
- Prostate Cancer645
- Bladder Cancer186
- Acute Kidney Injury133
- Chronic Kidney Diseases123
- Chronic Kidney Disease107
- Breast Cancer105
- Renal Cell Carcinoma80
- Urinary Incontinence60
- Kidney Cancer59
- Colorectal Cancer58
- Ovarian Cancer57
- Lung Cancer51
- Cancer48
- Lupus Nephritis48
- Melanoma48
- Metastatic Prostate Cancer47
- Head and Neck Cancer46
- Prostate Cancer (Adenocarcinoma)45
Leading sponsors
- Mayo Clinic64
- National Cancer Institute (NCI)48
- Peking University First Hospital39
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals34
- Chinese University of Hong Kong33
- AstraZeneca29
- IRCCS Azienda Ospedaliero-Universitaria di Bologna29
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris27
Where studies are running
- California359
- Arizona109
- Alabama107
- Florida95
- New York95
- Maryland91
- Texas91
- Massachusetts89
- Illinois66
- Minnesota50
Recruiting studies4,387 total
- NCT05817903RecruitingPhase 2
Nivolumab with or without axitinib after prior nivolumab
This Phase 2 trial studies whether adding axitinib to nivolumab (or giving nivolumab alone) can better control advanced clear-cell kidney cancer after standard initial treatment with nivolumab plus ipilimumab. It may help by extending response or slowing tumor growth while improving how long treatment works.
BresciaAges 18 years+ - NCT05209243Recruiting
Treating limited-spread prostate cancer with radiation plus hormone therapy
This trial studies whether adding focused radiation (SBRT) to hormone therapy can control prostate cancer that has spread to only a few places. It aims to help people with early “oligometastatic” prostate cancer by improving disease control while limiting treatment side effects.
MadridAges Any age - NCT05884632Recruiting
Personalized daily radiation for prostate cancer after surgery
This trial studies a “daily adaptive” way of planning and delivering radiation after prostate surgery to treat prostate cancer that is coming back locally. It may help target the tumor more precisely while limiting radiation to healthy tissue.
Negrar, VeronaAges 18–80 - NCT05888909Recruiting
Tests better diagnosis and treatment planning for kidney disease in type 2 diabetes
This trial focuses on improving how kidney damage is diagnosed and how treatment is planned for people with type 2 diabetes and kidney disease. It may help by using detailed medical history and (if done) kidney biopsy results to guide care more accurately.
BeijingAges 18 years+ - NCT04519151RecruitingPhase 2
Pembrolizumab plus lenvatinib for ovarian cancer that returned
This Phase 2 trial tests whether pembrolizumab plus lenvatinib can shrink ovarian cancer that has come back after platinum chemotherapy. You may be eligible if your cancer returned after a certain “time off” from prior treatment and you meet key health and safety requirements.
Ramat GanAges 18 years+ - NCT05753839Recruiting
Testing surgery plus immunotherapy for metastatic kidney cancer
This trial studies whether removing the kidney tumor (cytoreductive nephrectomy) before treatment can improve outcomes for people with metastatic clear-cell kidney cancer. All participants are expected to receive standard immunotherapy (nivolumab plus ipilimumab), and the study focuses on the role of surgery in the “immuno-oncology era.”
SeoulAges 18 years+ - NCT05738525Recruiting
Compare two types of home dialysis for kidney outcomes and quality of life
This study compares two forms of home peritoneal dialysis—how well they work for kidney health and how they affect daily life. You may be considered if you have end-stage kidney disease and meet specific test and safety requirements.
Beijing, Beijing MunicipalityAges 18–75 - NCT04654338RecruitingPhase 2/Phase 3
Two types of targeted radiation for favorable prostate cancer
This trial tests whether two “ablative” (high-dose, focused) radiation treatments can work well for men with favorable-risk prostate cancer. It looks at whether the treatments are practical and safe, especially for urinary side effects.
Toronto, OntarioAges Any age - NCT05938881Recruiting
Follow-up study of a vaginal mesh surgery for pelvic organ prolapse
This trial is a follow-up for women who were already part of an earlier randomized study. It looks at how well the vaginal mesh surgery works over the long term and whether it continues to help symptoms safely.
Foshan, GuangdongAges 53–75 - NCT05943379RecruitingPhase 2
RC48 antibody plus gemcitabine for high-risk bladder cancer
This Phase 2 study tests RC48, an antibody-based drug, combined with gemcitabine to treat high-risk, non-muscle invasive bladder cancer that has not responded well to BCG or cannot receive BCG. It may help shrink tumors and reduce the chance of the cancer coming back.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05508009RecruitingPhase 1/Phase 2
Kidney transplant with donor-matched stem cell treatment
This early-phase trial tests a stem cell transplant from a donor who is an extremely close match, given to people who are about to receive a kidney transplant from the same donor. The goal is to improve how well the new kidney works by resetting the immune system to better accept the transplant.
Palo Alto, CaliforniaAges 1–30 - NCT05963126Recruiting
Fetuin A test to predict kidney function decline
This study looks at a blood protein called fetuin A to see if it can forecast worsening kidney function over time in people with treated high blood pressure. It may help identify who is at higher risk for kidney decline so care can be adjusted earlier.
Ostrava, Czech RepublicAges 18–100 - NCT05977231Recruiting
Conservative care for women’s urine leakage problems
This trial looks at how well non-surgical treatments help women with urinary incontinence (urine leakage). You may be eligible if you’re able to follow up regularly for at least a year and plan to stay with conservative, non-surgical care.
New Taipei CityAges 20–100 - NCT05224401RecruitingPhase 3
Oral antibiotic step-down for ESBL bladder infections
This Phase 3 trial tests whether switching from short-term IV antibiotics to an oral antibiotic combo is safe and effective for ESBL urine infections. It may help you avoid staying on IV antibiotics as long, if your bacteria are the right match.
HelsingborgAges 18–130 - NCT02298465Recruiting
Shockwave treatment for a kidney stone: lying down two ways
This trial studies whether kidney-stone shockwave treatment works better when you lie on your back (supine) versus on your stomach (prone). It focuses on adults with a stone in the lower part of the urine tube (the distal ureter).
Hong KongAges 18 years+ - NCT05983783RecruitingPhase 3
Testing two drug combinations for advanced prostate cancer
This trial compares two combinations of drugs for men with metastatic hormone-sensitive prostate cancer that has a high tumor burden. One group gets rezvilutamide plus hormone therapy and chemotherapy, while the other gets rezvilutamide plus hormone therapy alone. The goal is to see which is more effective and safe.
Nanjing, JiangsuAges 40–80 - NCT06001619RecruitingPhase 4
Prostate medication, metabolism, and gut bacteria
This study looks at how prostate medication affects your metabolism and the helpful bacteria in your gut. It may help explain how these drugs work and how they affect your body.
TurkuAges 18 years+ - NCT05689866Recruiting
Study of bladder and sphincter symptoms in functional neurological disorders
This study looks at bladder and sphincter (urine control) symptoms in people with functional neurological disorders. It may help doctors understand what causes these symptoms and how to better treat them.
BobignyAges 18 years+ - NCT06026189Recruiting
Reducing cystoscopy for blood in urine
This trial tests if we can safely skip a bladder camera test (cystoscopy) for people who have microscopic blood in their urine. If you meet certain criteria, you may not need the procedure.
RotterdamAges Any age - NCT04463316Recruiting
Clinic study for people with rare genetic conditions
This study is for people who have a rare syndrome or rare congenital condition and are seen at a rare-disease clinic. It aims to better understand these conditions and how care works in a team setting, which may help guide future treatment decisions.
Rotterdam, South HollandAges 18 years+ - NCT05620784RecruitingPhase 3
Loop water pills during surgery to go home sooner after HoLEP
This trial tests whether giving a “loop diuretic” water pill during surgery can help people after HoLEP go home the same day more often. It’s mainly looking to improve discharge timing while keeping you safe.
Chicago, IllinoisAges 18–89 - NCT03379909RecruitingPhase 2
Metformin taken by mouth for early bladder cancer
This trial studies whether a diabetes medicine called metformin can help prevent or control non-muscle-invasive bladder cancer inside the bladder. You would take it by mouth, and the study checks safety and whether it works.
Nijmegen, GelderlandAges 18 years+ - NCT06050148RecruitingPhase 2/Phase 3
Fecal Transplant to Prevent Repeat Urinary Tract Infections
This trial tests whether a fecal microbiota transplant (a procedure that transfers healthy bacteria from a donor's stool into your gut) can help prevent repeat urinary tract infections in women who have frequent infections.
HelsinkiAges 18–90 - NCT04549688Recruiting
Active surveillance with focused ultrasound for prostate cancer
This trial studies whether a high-intensity focused ultrasound treatment can help people with localized prostate cancer while still avoiding traditional full-dose treatment for some patients. It may be an option for certain intermediate-risk cases where the cancer is confined to the prostate.
Tønsberg, VestfoldAges 18–80
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,387 recruiting nephrology & urology studies from the U.S. registry right now, out of 6,805 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.