Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,502 recruiting studies in this area right now.
By phase
- Not applicable2,817
- Phase 2566
- Phase 1365
- Phase 3272
- Phase 1/Phase 2230
- Phase 4194
- Phase 2/Phase 358
Top conditions
- Prostate Cancer651
- Bladder Cancer191
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Chronic Kidney Disease105
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer55
- Lupus Nephritis54
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Prostate Cancer (Adenocarcinoma)46
- Head and Neck Cancer45
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals35
- Chinese University of Hong Kong34
- AstraZeneca31
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California349
- Alabama112
- Arizona104
- Florida96
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,502 total
- NCT07508787RecruitingPhase 2
Study comparing siplizumab to another drug for kidney transplant acceptance
This trial tests a new drug, siplizumab, to see if it helps the body accept a donated kidney better than a standard treatment. It is for people receiving a kidney transplant from a living or deceased donor.
Sacramento, CaliforniaAges 18–70 - NCT07620574Enrolling by invitationPhase 3
Long-Term Study Continuing Cancer Treatment from Previous Trial
This study lets people who were in an earlier Exelixis cancer treatment trial continue receiving the same treatment if it's still helping them. It's designed to see how safe and effective the treatment is over a longer period.
Bay Shore, New YorkAges Any age - NCT06966024RecruitingPhase 1
Study of DCC-2812 for advanced genitourinary cancers
This trial tests an experimental pill called DCC-2812 for people with advanced kidney, bladder, or prostate cancer. The goal is to see if it is safe and if it might help shrink tumors or slow the cancer's growth.
Boston, MassachusettsAges 18 years+ - NCT06770582RecruitingPhase 2
Adding immunotherapy to radiation for bladder cancer
This trial tests whether adding the immunotherapy drug pembrolizumab to radiation therapy works as well as or better than the usual chemotherapy given with radiation for a type of bladder cancer that has not invaded the muscle. It is for people whose cancer came back or has high-risk features and who would otherwise need to have their bladder removed.
Fayetteville, ArkansasAges 18 years+ - NCT07763613Recruiting
Study of pelvic floor strength after kidney stone surgery
This study measures a new score called the pelvic floor fatigue index, which looks at how tired the pelvic floor muscles get, in people who have a ureteral stent placed after kidney stone surgery. The goal is to see if this score can help predict or prevent bladder problems that stents can cause.
Trabzon, TrabzonAges 18–65 - NCT07768865Recruiting
Artery stiffness in young people with kidney disease
This study looks at how stiff the arteries are in children and young adults with chronic kidney disease (CKD) compared to healthy controls. The results may help doctors better understand heart risks and improve care for young people with kidney problems.
London, Greater LondonAges 10–25 - NCT06940271Recruiting
Nerve wrap procedure during prostate surgery to help preserve erectile function
This study tests wrapping the nerves next to the prostate with a special tissue graft during prostate cancer surgery. The goal is to see if it helps keep erectile function after surgery.
Jacksonville, FloridaAges 45 years+ - NCT07615101RecruitingPhase 3
PET scan imaging test for newly diagnosed prostate cancer
This study tests a new imaging agent (68Ga-NYM032) used with PET/CT scans to help doctors better detect prostate cancer before surgery. If you have biopsy-confirmed prostate cancer and are planning to have your prostate removed, this trial may help evaluate whether this new imaging method improves cancer detection.
Nanjing, JiangsuAges 18 years+ - NCT06957691RecruitingPhase 2
Fezolinetant for hot flashes in men on hormone therapy
This study tests a medication called fezolinetant to see if it reduces hot flashes in men undergoing hormone therapy for prostate cancer. If you experience frequent hot flashes, this treatment might help alleviate them.
Boston, MassachusettsAges 40 years+ - NCT05519241RecruitingPhase 1
Experimental bladder cancer treatment for early-stage, BCG-unresponsive disease
This phase 1 trial tests a new treatment for early-stage bladder cancer that has not responded to BCG therapy. The treatment is given directly into the bladder (intravesical), which may help avoid removing the bladder.
Boston, MassachusettsAges 18 years+ - NCT06206486Recruiting
Gut germs and pain after kidney transplant
This study looks at whether the germs in your gut (microbiome) and certain chemicals in your blood affect pain after a kidney transplant. By joining, you may help doctors better understand and manage pain for future kidney transplant patients.
Chicago, IllinoisAges 18 years+ - NCT07421700RecruitingPhase 1/Phase 2
Study of PF-08634404 alone or with enfortumab vedotin for bladder cancer
This trial tests a new drug, PF-08634404, either by itself or together with another drug called enfortumab vedotin, for people with advanced bladder cancer that has spread. The goal is to see if these treatments can shrink tumors or slow the cancer's growth.
Fayetteville, ArkansasAges 18 years+ - NCT06858319RecruitingPhase 3
Long-term study of zigakibart for IgA nephropathy
This study is for people with IgA nephropathy who completed a previous zigakibart study. It tests whether continuing treatment with zigakibart (given as a shot every two weeks) is safe and helpful over a longer period.
Denver, ColoradoAges 18–100 - NCT06842498RecruitingPhase 2
FG-3246 for advanced prostate cancer
This trial tests a new drug called FG-3246, which targets a protein (CD46) on prostate cancer cells. It's for men with advanced prostate cancer that has spread and stopped responding to standard hormone therapy, and who have had limited prior treatments.
Goodyear, ArizonaAges 18 years+ - NCT07570862RecruitingPhase 2
CAR T-Cell Therapy for Hard-to-Treat Lupus Kidney Disease
This trial tests FT819, a new type of immune cell therapy (CAR T cells), for people with lupus nephritis—kidney inflammation caused by lupus—who haven't responded well to standard treatments. The goal is to see if this therapy can reduce kidney damage and improve kidney function.
Beverly Hills, CaliforniaAges 12–70 - NCT07202247RecruitingPhase 2
Improving heart health in prostate cancer patients on hormone therapy
This study tests whether combining a time-restricted eating plan, a heart-healthy diet, and a weight-loss medication (GLP-1 receptor agonist) can help improve heart health and weight in men with prostate cancer who are receiving hormone therapy. It aims to reduce the risk of heart problems caused by hormone treatment.
Duarte, CaliforniaAges 30–79 - NCT07692789Recruiting
Phone reminders before a bladder test
This study tests if phone calls and MyChart reminders help women prepare for a urodynamics test (a test that checks how your bladder works). You may be able to take part if you are a woman scheduled for this test at certain Ohio State clinics.
Columbus, OhioAges 18 years+ - NCT06884410Recruiting
Reproducibility of kidney MRI scans on 1.5 Tesla machines
This study checks whether kidney MRI scans give consistent results when repeated. Healthy adults with normal blood pressure and kidney function are needed to help improve MRI techniques for future patients.
AarhusAges 18–70 - NCT06604403Recruiting
Massage for people on hemodialysis
This trial tests if massage therapy during dialysis sessions can improve comfort or well-being. It's for people who have been on hemodialysis for at least 6 months and can communicate easily.
Erzurum, YakutiyeAges 18 years+ - NCT03855722Recruiting
Remote heart protection before organ transplant
This study tests whether a simple treatment performed on the donor before organ removal can help transplanted organs work better. It may help patients receiving organs from eligible brain-dead donors at a specific hospital.
HelsinkiAges 18 years+ - NCT07764991RecruitingPhase 2
Lactoferrin supplement for diabetic kidney disease
This study tests whether taking a lactoferrin supplement can help people with type 2 diabetes and chronic kidney disease (stage 3 or 4) by reducing protein in their urine, which is a sign of kidney damage. It may offer a new way to slow the progression of kidney disease.
CairoAges 18–75 - NCT05126472RecruitingPhase 1/Phase 2
Study of 2141-V11 for bladder cancer that did not respond to standard treatment
This trial tests a new drug, 2141-V11, for people with bladder cancer that has not gone away after standard treatments like BCG therapy. It may help those with non-muscle invasive bladder cancer or, in one group, muscle-invasive bladder cancer, who cannot have or choose not to have bladder removal surgery.
Basking Ridge, New JerseyAges 18 years+ - NCT06738303RecruitingPhase 2
Cabazitaxel with or without carboplatin vs lutetium PSMA for prostate cancer
This trial compares two treatment approaches for advanced prostate cancer that has stopped responding to hormone therapy. One group gets chemotherapy (cabazitaxel with or without carboplatin) and the other gets a targeted radiation therapy (177Lu-PSMA-617). The goal is to see which works better.
Cleveland, OhioAges 19 years+ - NCT07753720RecruitingPhase 4
Daily tadalafil with or without another treatment for erectile dysfunction
This study tests whether taking tadalafil daily, either alone or with a second treatment, works better for men with erectile dysfunction who have not responded to on-demand pills. It aims to help men who have not had success with current treatments.
CairoAges 18–70
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,502 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,145 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.