Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,626 recruiting studies in this area right now.
By phase
- Not applicable4,298
- Phase 2850
- Phase 1470
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Ovarian Cancer72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Colorado71
Recruiting studies6,626 total
- NCT05150093Recruiting
Deep brain stimulation for voice tremor or dystonia
This trial studies deep brain stimulation (a surgically placed device that sends electrical signals) to reduce voice tremor or laryngeal dystonia. You may be considered if your symptoms are persistent despite medication and you can complete the study tasks and pre-surgery testing.
Boston, MassachusettsAges 18–80 - NCT05150106Recruiting
Study brain and voice patterns in laryngeal dystonia
This study looks at how the brain and voice system work in people with laryngeal dystonia or voice tremor, and compares them with healthy volunteers. The goal is to better describe different “types” (phenotypes) so future care can be more targeted.
Boston, MassachusettsAges 18–80 - NCT05150483Recruiting
Study of a blood test in new severe breathing failure
This trial looks at how a test might help evaluate adults who come to the emergency room with a brand-new, sudden breathing problem that needs high-flow oxygen. It may help doctors identify what’s going on faster and guide care in the early hours.
Athens, AtticaAges 18 years+ - NCT05156112Recruiting
PAP breathing treatment for veterans with PTSD and substance use
This trial studies whether using a PAP breathing device (a machine that helps keep airways open during sleep) can help veterans who have PTSD and a substance use disorder while they receive residential treatment. It’s specifically for people with obstructive sleep apnea and aims to see if this treatment is safe and helpful during recovery.
San Diego, CaliforniaAges 18 years+ - NCT05157685RecruitingPhase 3
Azithromycin for chronic pus-filled sinus inflammation
This Phase 3 trial tests whether the antibiotic azithromycin can improve chronic sinus problems where there is persistent pus and swelling. It’s for adults who have not improved despite at least two prior antibiotics.
BordeauxAges 18–70 - NCT05164744Recruiting
MRI study of heart tissue changes after COVID-19
This study uses a heart MRI to look for leftover (healing) changes in heart tissue after COVID-19. It may help researchers better understand what ongoing heart effects can happen after infection.
Brooklyn, New YorkAges 18 years+ - NCT05167487Recruiting
Study of treatment effects after chemotherapy and surgery for lung cancer
This trial looks at how lung tumors respond after chemotherapy given before surgery in people with stage IIIA non-small cell lung cancer (NSCLC). It may help doctors understand which past treatments lead to better results, since it uses medical records from approved clinical cases.
A Coruña, A CoruñaAges 18 years+ - NCT05168566RecruitingPhase 2
Sutetinib for lung cancer with a specific EGFR change
This Phase 2 study tests sutetinib capsules in people with advanced (locally advanced or metastatic) non-small cell lung cancer. It’s for tumors that have a specific, uncommon EGFR mutation, and aims to see how well the drug can control the cancer with limited prior chemotherapy.
Glendale, CaliforniaAges 18 years+ - NCT05171478Recruiting
Test imaging on small lung biopsy samples during bronchoscopy
This study uses a special eye-like scanning camera (full-field optical coherence tomography) to look at tiny lung tissue samples taken during routine bronchoscopy. It may help doctors learn more from small biopsies used to diagnose or stage lung problems.
Baltimore, MarylandAges 18 years+ - NCT05172739RecruitingPhase 4
Opioid-free anesthesia during lung surgery for early lung cancer
This study tests whether an opioid-free pain/anesthesia plan during elective lung surgery can reduce surgical “stress” on the body and affect the immune system. You may be eligible if you have early-stage non-small cell lung cancer and are scheduled for a specific type of surgery (VATS lobectomy).
Heraklion, CreteAges 18–80 - NCT05176132Recruiting
Obesity screening to find hidden weight-related health issues
This study screens adults of different body sizes to find “unrecognized” weight-related health problems. It may help doctors spot issues earlier and understand how common they are across weight groups.
EsbjergAges 18–60 - NCT05178277Recruiting
Alpha-1 antitrypsin deficiency registry study
This study collects health information from people who have alpha-1 antitrypsin deficiency. It may help doctors better understand the condition and improve care over time.
Prague, Czech RepublicAges Any age - NCT05179408Recruiting
Video rehab after lung cancer treatment for Veterans
This trial tests whether targeted rehab done by video (telerehabilitation) can help Veterans recover after curative (aim-to-cure) lung cancer treatment. It mainly focuses on people who have recently finished surgery or radiation/chemo-radiation and may benefit from guided exercise from home.
Aurora, ColoradoAges 18 years+ - NCT05179876RecruitingPhase 3
Treatment access study for pulmonary hypertension when no other option
This Phase 3 study continues treatment for people with pulmonary hypertension who finished an earlier parent study and have no other approved treatment option. It tests whether continuing their current medicine can help them keep getting benefit and stay safe.
MinskAges 2 years+ - NCT05181696Recruiting
Study of chest X-ray severity scores in ICU COVID-19 pneumonia
This study reviews past chest X-rays from people who were hospitalized in the ICU for COVID-19 pneumonia caused by SARS-CoV-2. It aims to see how well a chest X-ray severity scoring system reflects how sick the lungs were.
OsijekAges 18–90 - NCT05187338RecruitingPhase 1/Phase 2
Study drugs that target immune checkpoints for solid tumors
This early-phase study tests a combination of three immune “checkpoint” medicines in people with advanced solid cancers. It aims to see how well they work and what side effects occur, including when given through a specific liver-focused treatment in eligible patients.
Guangzhou, GuangdongAges 18–70 - NCT05188612Recruiting
Hospital patients with confirmed COVID-19 survey study
This study collects information from adults who are in the hospital for confirmed COVID-19. The goal is to better understand what happens during acute (early) COVID-19 and improve care.
Bologna, BolognaAges 18 years+ - NCT05188859RecruitingPhase 2
Testing sintilimab, anlotinib, and chemo for pleural mesothelioma
This Phase 2 study tests whether adding three medicines—sintilimab, anlotinib, and standard platinum chemo—can control malignant pleural mesothelioma that cannot be removed by surgery. It may help shrink tumors and slow disease progression, but you must meet specific health and prior-treatment requirements.
Taiyuan, ShanxiAges 18 years+ - NCT05189496Recruiting
Hyperbaric oxygen to help prevent radiation-related lung injury
This trial tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen) can prevent lung inflammation caused by breast cancer radiation. It may help reduce the risk of radiation pneumonitis in certain breast cancer survivors.
Guangzhou, GuangdongAges 18–70 - NCT05190718Recruiting
Pharyngeal electrical stimulation for swallowing trouble after brain injury
This trial tests a non-drug therapy that uses gentle electrical stimulation to help people swallow safely when swallowing is affected by certain brain or nerve conditions. If you qualify, you may receive this approach to improve swallowing and reduce choking risk.
Tulln, Low AustriaAges 18 years+ - NCT05191381Recruiting
Immune treatment using exosome therapy for severe COVID-19
This trial tests whether immune-supporting treatment made from exosomes can help people with critically severe COVID-19 and lung damage. If you qualify, you may receive this therapy as part of the study to see if it improves outcomes.
UlmAges 18–90 - NCT05192499Recruiting
Study gut-and-lung bacteria in very young children with asthma
This study looks at whether differences in the body’s bacteria (in the gut and/or airways) can help predict which toddlers with asthma may develop a more severe form. It may help doctors identify children at higher risk earlier so they can be monitored more closely.
Brest, FinistèreAges 1–3 - NCT05193136Recruiting
Testing sleep and exercise effects on strength and thinking in lung disease
This trial studies whether improving sleep habits can help people with lung conditions like COPD or IPF maintain muscle strength and thinking (cognitive function). It may help by addressing sleep quality and related health factors, but eligibility depends on your current diagnoses and treatments.
Jōyō, KyotoAges 20 years+ - NCT05194982RecruitingPhase 1
Early study drug BL-B01D1 for advanced solid tumors
This Phase 1 trial tests BL-B01D1 in people with advanced or metastatic solid tumors that are not curable or lack standard treatment options. The goal is to see how the drug works in the body and whether it’s safe enough to study further.
Chongqing, Chongqing MunicipalityAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,626 recruiting pulmonology studies from the U.S. registry right now, out of 10,582 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.