Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06943235RecruitingPhase 2
Probiotics, radiation, chemo, and immunotherapy for limited-stage small cell lung cancer
This trial tests if adding probiotics (good bacteria) to standard chemoradiation and an immunotherapy drug (adebrelimab) can help treat limited-stage small cell lung cancer. It may improve how well the treatment works and reduce side effects.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06950515Recruiting
Anesthesia vs sedation for lung nodule biopsy
This trial compares general anesthesia with conscious sedation during a special ultrasound-guided lung biopsy. It aims to find which approach is safer and more comfortable for diagnosing small lung lesions.
Québec, QuebecAges 18 years+ - NCT06947694RecruitingPhase 2
Testing radioimmunotherapy combinations for lung cancer with metastases
This trial explores whether combining radiation therapy with immunotherapy can trigger an immune response that shrinks tumors throughout the body (abscopal effect) in people with non-small cell lung cancer that has spread to 3 to 6 other sites. It tests different patterns of these treatments to see which works best.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06950073Recruiting
Second radiation treatment for lung cancer in the chest
This study tests whether giving a second course of radiation to the chest (called retreatment) can control lung cancer that has come back or a new cancer that started there. People who have already had radiation to their chest and are healthy enough for more may be eligible.
Aarhus, JutlandAges Any age - NCT06950294RecruitingEarly Phase 1
Inhaled nitric oxide for pneumonia patients on a ventilator
This study tests an inhaled gas (iNO300) given through your breathing tube to improve oxygen levels in critically ill patients with pneumonia. You may qualify if you are on a ventilator and have been diagnosed with pneumonia within the last 3 days.
Boston, MassachusettsAges 18 years+ - NCT06946927RecruitingPhase 1
Study of JMKX001899 with other drugs for advanced KRAS G12C lung cancer
This trial tests a new targeted therapy, JMKX001899, combined with other treatments for advanced non-small cell lung cancer that has a specific KRAS G12C mutation. It aims to see if this combination can help shrink tumors or slow cancer growth.
Guangzhou, GuangdongAges 18–75 - NCT06944925RecruitingPhase 1
Study of BBT002 for COPD and Nasal Polyps
This trial tests a new drug, BBT002, first in healthy volunteers and then in people with chronic obstructive pulmonary disease (COPD) or chronic sinusitis with nasal polyps. It aims to see if the drug is safe and how it works in the body.
Bowling Green, KentuckyAges 18–80 - NCT06942143RecruitingPhase 1
Super1 TCR-T for NY-ESO-1 positive advanced solid tumors
This trial tests an experimental treatment called Super1 TCR-T, which is a type of immunotherapy designed to attack tumors that have a specific protein (NY-ESO-1). It is for people with advanced solid tumors whose first treatment has stopped working and who also have a certain genetic marker (HLA-A*02).
Guangzhou, GaungdongAges 18–75 - NCT06951217RecruitingPhase 2
Long-term safety study of an inhaled drug for lung scarring
This study continues treatment for people who already completed a previous study with an Avalyn inhaled antifibrotic drug. It aims to check the long-term safety of the medication for patients with certain types of lung scarring.
Birmingham, AlabamaAges 18 years+ - NCT06948487Recruiting
Study of Fexuclu tablets for stomach inflammation (gastritis)
This study watches patients with acute or chronic gastritis who are already being prescribed the stomach medicine Fexuclu (fexuprazan). It collects information to see how well the medicine works and if it causes any side effects in everyday use.
SeoulAges 19–75 - NCT06943521RecruitingPhase 1/Phase 2
Study of MT-4561 for advanced solid tumors
This trial tests a new drug called MT-4561 in people with advanced solid tumors that have not responded to prior treatments. It aims to see if the drug can help shrink tumors or slow their growth.
Los Angeles, CaliforniaAges 18 years+ - NCT05891886RecruitingEarly Phase 1
Testing supplemental oxygen for early blood clot in the lungs
This early-phase trial studies whether giving extra oxygen can help people with a recently diagnosed lung blood clot (pulmonary embolism). It mainly looks at people who have early symptoms and signs that the right side of the heart is under strain.
Boston, MassachusettsAges 18 years+ - NCT06039501Recruiting
The Family Perspectives Project Pilot Trial
This study looks at how to improve communication between families and the care team when a loved one is on a breathing machine in the intensive care unit. It may help families feel more supported and involved in care decisions.
Los Angeles, CaliforniaAges 18 years+ - NCT06766136Recruiting
Asthma education program based on the Roy Adaptation Model
This trial tests a new asthma education program designed to help you better manage your asthma symptoms and improve your quality of life. The program is based on the Roy Adaptation Model, which focuses on helping you adapt to your condition.
Niğde, CenterAges 18–64 - NCT06932237Recruiting
Immune causes of long COVID brain symptoms in veterans
This study is for veterans who have long COVID with brain or nerve symptoms. It looks at how the immune system may be causing these ongoing symptoms.
Portland, OregonAges 18–80 - NCT06932263RecruitingPhase 2
Study of a new asthma medicine for uncontrolled asthma
This study tests a new medicine called tozorakimab for adults whose asthma is not well controlled despite using their usual inhalers. It aims to see if it can reduce asthma attacks and improve symptoms.
Bakersfield, CaliforniaAges 18–75 - NCT06936735RecruitingPhase 1
HS-20108 for advanced solid tumors (phase 1)
This phase 1 study tests an investigational drug called HS-20108 in people with advanced solid tumors. It aims to find a safe dose and see how well the drug works against cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06933173Recruiting
Mind-body therapy for Long COVID and ME/CFS
This trial tests whether a specific mind-body program can help people with Long COVID or ME/CFS feel better. It compares the program to standard care to see if it improves symptoms like fatigue and brain fog.
Calgary, AlbertaAges 18 years+ - NCT06940427RecruitingPhase 2
Testing a new PET scan for lung scarring
This trial is testing a new type of PET scan (FAPI PET) to help doctors see if lung scarring (fibrosis) is getting worse or getting better. It may help decide if a treatment change is needed.
Madison, WisconsinAges 18 years+ - NCT06940856Recruiting
Chloride imbalance in preterm babies
This study looks at chloride levels in preterm babies admitted to the neonatal intensive care unit (NICU) within their first day of life. It aims to understand chloride imbalance and how it might affect their health.
Istanbul, TurkeyAges 1 hour–1 month - NCT06937450Recruiting
Chest tube washing for traumatic bleeding in the chest
This study tests whether daily washes through a chest tube help clear blood from the chest after an injury. If you have a large collection of blood in your chest, you may qualify for this treatment approach.
Philadelphia, PennsylvaniaAges 15 years+ - NCT06935825Recruiting
Breathing muscles in severe lung disease
This study looks at how the breathing muscles work in people with very advanced COPD who are waiting for a lung transplant. It aims to understand the problems these muscles face and how that affects patients.
AmsterdamAges Any age - NCT06937320Enrolling by invitationPhase 2
Testing ketone supplements for heart failure with preserved ejection fraction (HFpEF)
This study tests whether a special dietary supplement (ketone esters) can improve exercise ability and heart function in people with a type of heart failure where the heart pumps well but is stiff (HFpEF). You might join if you have stable symptoms, an ejection fraction of 50% or higher, and signs of fluid buildup in the heart.
Durham, North CarolinaAges 18 years+ - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.