Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06930404Recruiting
New ways to diagnose sleep apnea
This study tests new ways to diagnose obstructive sleep apnea. If you haven't been diagnosed with sleep apnea and are generally healthy, you may be able to join.
Sydney, New South WalesAges 18 years+ - NCT06922591RecruitingPhase 1/Phase 2
TNG462 for pancreatic and lung cancer with MTAP loss
This trial tests a new drug called TNG462, alone or combined with other drugs, for people with advanced pancreatic or non-small cell lung cancer whose tumors have a specific genetic change (loss of MTAP and a RAS mutation). It aims to see if TNG462 is safe and works better than current treatments.
Scottsdale, ArizonaAges 18 years+ - NCT06922539RecruitingPhase 1
Experimental drug ST-001 nanoFenretinide for small cell lung cancer
This phase 1 trial tests an experimental drug called ST-001 nanoFenretinide for people with small cell lung cancer that has returned or not responded to standard chemotherapy. The drug is a newer form of fenretinide, which is related to vitamin A, and may work differently to attack cancer cells.
Los Angeles, CaliforniaAges 18 years+ - NCT06923774Recruiting
Registry study for lung biopsy with Ion system
This study collects information from patients having a lung biopsy or nodule localization using the Ion endoluminal system. It aims to understand how well the system works in real-world settings.
BrestAges 18 years+ - NCT06928389RecruitingPhase 3
Ivonescimab plus docetaxel for advanced lung cancer
This trial tests a new drug called ivonescimab combined with a chemotherapy drug (docetaxel) for advanced non-small cell lung cancer. It's for people who have already tried platinum-based chemo and a PD-1/PD-L1 inhibitor, and who have not had docetaxel before.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06931626RecruitingPhase 1
Study of NMS-03305293 for relapsed small cell lung cancer
This trial tests a new drug, NMS-03305293, in adults with small cell lung cancer that has come back after earlier treatments. The goal is to see if it can help shrink or slow the cancer.
Peoria, IllinoisAges 18 years+ - NCT06276283RecruitingPhase 2
DZD9008 plus bevacizumab for EGFR-mutated advanced lung cancer
This trial tests a new targeted therapy (DZD9008) combined with a drug that blocks blood vessel growth (bevacizumab) for people with a specific type of advanced lung cancer (EGFR mutation). The goal is to see if this combination works better than current treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06819943Recruiting
Bed positioning to reduce pressure on the body
This study tests a special bed positioning technique (lateralization therapy) to see if it lowers pressure on the body and helps prevent bedsores in people on breathing machines. If you are on a ventilator and not yet ready to breathe on your own, this trial may help improve your comfort and skin health.
São Paulo, São PauloAges 18 years+ - NCT05780099Recruiting
Study of patients treated in internal medicine clinics
This observational study follows people receiving care in Internal Medicine at San Raffaele Hospital to better understand what kinds of conditions they have. It does not test a new treatment, but your information may help improve future care.
MilanAges 18 years+ - NCT06920628RecruitingPhase 1
Brain scan study for long COVID neurological symptoms
This study uses a special PET scan to look at brain inflammation in people with neurological symptoms after COVID-19. It aims to understand how inflammation might be linked to ongoing problems like brain fog or memory issues.
Bethesda, MarylandAges 18–70 - NCT06917079RecruitingPhase 1
BBO-11818 for KRAS-mutated cancers
This trial tests a new oral drug (BBO-11818) for people with solid tumors that have a specific KRAS mutation. It's for those whose cancer has spread or cannot be removed by surgery and who have not had other cancers recently.
Los Angeles, CaliforniaAges 18 years+ - NCT06911632Recruiting
AI-assisted check for pulmonary hypertension in interstitial lung disease
This study uses an AI tool to help doctors decide if you should be tested for pulmonary hypertension (high blood pressure in the lungs), which can be a complication of interstitial lung disease. If the tool suggests you might have it, you may get an echocardiogram (an ultrasound of the heart) and a right heart catheterization (a test to measure pressure in the heart) to find out for sure.
Birmingham, AlabamaAges 18 years+ - NCT06914128RecruitingPhase 1/Phase 2
Study of a PRMT5 inhibitor for MTAP-deleted solid tumors
This trial tests a new drug called BAY 3713372 in people with solid tumors that have a specific genetic change called MTAP deletion. The drug targets a process inside cells that may help stop tumor growth.
Birmingham, AlabamaAges 18 years+ - NCT06920407Enrolling by invitation
BreatheWell: Breathing and relaxation for health
This research study tests a simple breathing and relaxation program called BreatheWell. If you are a generally healthy adult who isn't taking certain medications or using fitness trackers, you may be able to join and learn techniques to calm your body and mind.
Los Angeles, CaliforniaAges 18 years+ - NCT06912945Enrolling by invitation
Laser vs. standard tools for benign voice box growths
This study compares using two types of diode laser (980 nm and 450 nm) to traditional cold instruments for removing non-cancerous growths on the voice box. The goal is to see which approach works better based on the type of growth, patient factors, and laser settings.
Sohag, Sohag GovernorateAges Any age - NCT06921993Recruiting
Study: Using Ultrasound to Guide Antibiotic Use in Childhood Pneumonia
This study tests if lung ultrasound can help doctors decide whether to use antibiotics for children with pneumonia. If your child has signs of pneumonia but is stable enough for an ultrasound, this could help avoid unnecessary antibiotics.
San Diego, CaliforniaAges 3–10 - NCT06916104Enrolling by invitation
Allergies and biotherapy in severe asthma
This study looks at whether having a respiratory allergy affects how well biotherapy works for people with severe asthma. It includes adults already on biotherapy and followed at Poitiers University Hospital.
PoitiersAges 18 years+ - NCT06915441RecruitingPhase 2
Lipid infusions to improve nutrition for premature babies
This trial tests whether giving fat (lipid) infusions can improve nutrition and growth in very premature or very low birth weight babies. It may be for babies born before 28 weeks or weighing 1,000 grams or less.
Houston, TexasAges 12 hours–6 months - NCT06920199RecruitingEarly Phase 1
Donor Treg cells plus IL-2 for stubborn chronic GVHD
This trial tests whether injecting special immune cells (Treg cells) from your transplant donor, along with a protein called IL-2, can help control chronic graft-versus-host disease (cGVHD) that hasn't responded well to steroids. It is for people who have had a stem cell transplant and still have moderate to severe cGVHD.
ShanghaiAges 18–70 - NCT06919874Recruiting
Yoga app for lung or esophageal cancer patients and their caregivers
This trial tests a mobile app that guides patients with lung or esophageal cancer and their family caregivers through yoga exercises. It aims to improve well-being during radiation treatment.
Houston, TexasAges 18 years+ - NCT06919484Recruiting
RCexp effect on lung air and blood flow in ARDS
This study tests a new technique (RCexp) to see how it affects air and blood flow in the lungs of people with ARDS who are on a breathing machine. It aims to improve how we monitor and treat lung problems.
Nanjing, JiangsuAges 19 years+ - NCT06916598Enrolling by invitation
Defining lung complications after surgery
This study aims to create a clear, agreed-upon definition for lung problems after surgery. It's not a treatment trial but a way to help doctors and patients better identify and grade these complications.
Wolverhampton, WolverhamptonAges 18 years+ - NCT06915077Enrolling by invitation
Personalized treatment for sleep apnea
This study tests alternative treatments for people with moderate to severe sleep apnea who cannot use CPAP. It aims to find more tolerable options.
Wilrijk, AntwerpenAges 18 years+ - NCT06917222Recruiting
Comparing two surgeries for narrowed windpipe
This trial compares two surgical techniques to repair a narrowed windpipe caused by injury, trauma, or long-term breathing tube use. The goal is to find which approach works best for patients who need surgery for severe or moderate narrowing.
Al MansurahAges Any age
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.