Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06582745RecruitingPhase 2
Trametinib for Langerhans cell histiocytosis (LCH)
This trial tests a targeted drug called trametinib (a MEK inhibitor) for people with Langerhans cell histiocytosis (LCH) that is newly diagnosed, relapsed, or hasn't responded to other treatments. It aims to see if trametinib can better control the disease with fewer side effects.
Fort Worth, TexasAges 1–30 - NCT06582940RecruitingPhase 2
MRI-guided radiation for lung cancer with brain metastases
This trial tests a new way to deliver radiation to brain metastases from non-small cell lung cancer, using MRI scans to guide the treatment and reduce the area exposed. The goal is to see if this approach is safe and effective while possibly lowering side effects.
Guangzhou, GuangdongAges 18–75 - NCT06584786RecruitingEarly Phase 1
Jing Si Herbal Tea for COPD
This trial tests whether Jing Si Herbal Tea can help people with COPD feel better. If you have COPD and want to try a natural approach, this study might be for you.
New Taipei City, XindanAges 20 years+ - NCT06585020RecruitingPhase 2
Inhaled antibiotic for Mycobacterium xenopi lung infection
This trial tests an inhaled antibiotic (amikacin liposome) for people with a lung infection caused by a germ called Mycobacterium xenopi. The goal is to see if this treatment can help fight the infection with fewer side effects.
AmiensAges 18 years+ - NCT06585241RecruitingPhase 4
Study of Updated COVID-19 Vaccines for High-Risk Groups
This trial tests updated COVID-19 vaccines designed to better protect against current variants. It's for people who have already been vaccinated and are at higher risk for severe COVID-19.
Atlanta, GeorgiaAges 6 months+ - NCT06585358Recruiting
Precision Dosing for Pulmonary Tuberculosis
This trial tests a personalized approach to dosing the TB medicine rifampin. By using a computer model based on your individual factors, doctors hope to find the right dose for you, which may improve treatment outcomes.
LinköpingAges 18 years+ - NCT06586268Recruiting
Sleep changes after surgery in people with sleep apnea
This study looks at how sleep patterns change in the first three nights after surgery for people who have obstructive sleep apnea (OSA). It aims to understand how anesthesia and sleep apnea severity affect sleep quality during recovery.
Amsterdam, North HollandAges 18 years+ - NCT06586515RecruitingPhase 1
Testing a new drug for cancers with KRAS G12D mutation
This trial tests a new pill (LY3962673) for people whose cancer has a specific DNA change called KRAS G12D. The drug aims to block the faulty protein that helps the cancer grow, and the study will look at safety and whether the tumor shrinks.
Duarte, CaliforniaAges 18 years+ - NCT06586736Recruiting
Prone position study for ARDS patients
This trial studies how lying face down (prone position) affects breathing in patients with acute respiratory distress syndrome (ARDS). It may help doctors better monitor and treat patients on a breathing machine.
Chengdu, SichuanAges 18–90 - NCT06586957RecruitingPhase 1
Study of NKT3964 for advanced solid tumors
This trial is testing an experimental oral drug called NKT3964 for people with advanced solid tumors that have stopped responding to standard treatments. The drug works by blocking a protein called CDK2, which some cancers need to grow.
Little Rock, ArkansasAges 18 years+ - NCT06587256RecruitingPhase 2
Studying silicone mouth tape for snoring and mild sleep apnea
This trial tests if wearing silicone tape over your mouth at night can help reduce snoring and improve mild sleep apnea. You will use the tape and report how you and your partner feel about your snoring.
Baltimore, MarylandAges 18–75 - NCT06589245RecruitingPhase 1
Ciclesonide study for breathing support in preterm infants
This study tests an inhaled anti-inflammatory drug called ciclesonide for premature babies who need a breathing tube. It aims to see if the drug can help their lungs heal and reduce the need for steroids.
Kansas City, MissouriAges 1 week–1 month - NCT06589778RecruitingPhase 1/Phase 2
Study of three drugs for advanced lung cancer
This trial tests a combination of three drugs (SHR-A2102, Adebrelimab, and SHR-8068) for people with advanced non-small cell lung cancer that cannot be removed by surgery. It aims to see if this combination can shrink or slow the growth of the cancer.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06590324RecruitingPhase 2/Phase 3
Study of Apabetalone for long COVID
This trial tests an experimental drug called Apabetalone for people with long COVID. You may be eligible if you have type 2 diabetes, take or are willing to take dapagliflozin, and have had long COVID symptoms for at least 2 months after your COVID infection.
AmmanAges 18 years+ - NCT06591533Recruiting
Music therapy for children during breathing tube removal
This study uses music therapy to help children stay calm and have stable vital signs while their breathing tube is removed. It may help reduce stress during this important step.
Bogotá, Bogota D.C.Ages 1 month–17 years - NCT06592638RecruitingPhase 1
ZG006 for small cell lung cancer
This trial tests a new drug called ZG006 for people with small cell lung cancer that has not responded to or can no longer tolerate standard treatments. The goal is to find the best dose and see if it can help shrink or control the cancer.
Orange, CaliforniaAges 18–75 - NCT06593756Recruiting
Heart-Lung Support and Fluid Response Study
This study watches how your body responds to fluids while on VA ECMO (a heart-lung machine). The goal is to improve care for people needing this support.
ViennaAges 18–75 - NCT06593717Recruiting
Monitoring blood flow in VV-ECMO patients
This study tests how doctors can monitor your blood flow and fluid needs while you are on VV-ECMO. It involves a simple maneuver where your legs are raised to see if your heart needs more fluid.
ViennaAges 18–75 - NCT06594601Recruiting
Adjusting ventilator pressure for ARDS patients using 3D EIT
This study uses a special chest monitor to find the best ventilator pressure setting for people with ARDS on breathing machines. It aims to improve treatment by tailoring the pressure to each patient's lungs.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06595420Recruiting
Kidney health in people with cystic fibrosis on new treatments
This study looks at how the kidneys work in people with cystic fibrosis, especially those taking highly effective new treatments. It aims to understand kidney function in different groups, including those who are hospitalized frequently or rarely.
Birmingham, AlabamaAges 7 years+ - NCT06595784Recruiting
COPD and heart disease study
This study looks at people who have both COPD (a long-term lung condition) and a heart problem. The goal is to learn more about how these two conditions affect each other and to help doctors provide better care.
AlexandroupoliAges 35–99 - NCT06596915RecruitingPhase 1
BA1302 for advanced solid tumors
This trial tests a new drug, BA1302, for people with advanced solid tumors that have stopped responding to standard treatments. The study aims to see if BA1302 is safe and effective.
BeijingAges 18 years+ - NCT06597331Recruiting
Heart function study for COPD flare-ups
This study looks at how a COPD flare-up might affect the heart in people who haven't had a heart attack or known heart muscle damage before. It uses a simple heart ultrasound to check for stress-related changes.
Gothenburg, Region Västra GötalandAges 18 years+ - NCT06598319Recruiting
Pulsed field ablation for chronic rhinitis
This trial tests a new treatment that uses pulsed energy to target a nerve in the back of the nose to help with chronic rhinitis (long-term runny or stuffy nose). It is for people whose symptoms have not been controlled by nasal steroid sprays.
Colorado Springs, ColoradoAges 18–85
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.