Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06816121Recruiting
Blood test for early lung cancer in high-risk smokers
This study is evaluating a blood-based test that might detect lung cancer early, before symptoms appear. Researchers are looking for heavy smokers who have no signs of cancer, as well as those with suspicious lung nodules or confirmed lung cancer, to see if a simple blood draw could help identify cancer sooner.
Oklahoma City, OklahomaAges 30–80 - NCT06820749Enrolling by invitationPhase 2
Study of HSK31858 tablets for lung mucus conditions
This trial tests an investigational tablet for people with chronic lung diseases like bronchiectasis, COPD, or asthma who produce at least 10 mL of sputum (mucus coughed up from the lungs) each day. The goal is to see if the drug safely reduces excess airway mucus.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06819865Recruiting
EkoSonic device for acute pulmonary embolism in Chinese patients
This study tests if the EkoSonic device (used with a clot-busting medicine) is safe and effective for treating acute pulmonary embolism. It may be an option for people who have a large clot and an enlarged right heart chamber.
Guangzhou, GuangdongAges 18 years+ - NCT06819644RecruitingPhase 3
Adjusting oxygen therapy using a depth camera to measure lung volumes
This trial tests whether adjusting high flow oxygen therapy (which delivers warm, moist oxygen through the nose) based on a new, non-contact technology — a depth camera that measures lung volumes without touching you — can help improve breathing in people with low oxygen levels. It's for patients in respiratory distress who need oxygen but don't have chronic lung disease.
BrestAges 18 years+ - NCT06824402Recruiting
Cryoprobe Biopsy for Chronic Rejection in Lung Transplant
This trial tests a new biopsy method called cryoprobe (using a cold probe) to better detect chronic rejection in lung transplant patients. It is for patients who already need a lung biopsy, either for routine monitoring or because of a concern.
Rochester, MinnesotaAges 18–99 - NCT06820983Recruiting
Quality of life study for DDB with OPEP device
This study looks at how a breathing device called OPEP affects the quality of life of people with DDB (a lung condition that causes widening and damage to the airways). If you or your child has DDB and doesn't already use an OPEP device, this trial may help understand if starting one improves daily life.
AmiensAges 8 years+ - NCT06823622Recruiting
Digital transition care for teens with asthma or transplants
This trial tests a digital program to help teenagers with asthma, allergies, or organ transplants move from pediatric to adult healthcare. It aims to see if online support works as well as in-person visits.
Gothenburg, Vastra GotalandsregionenAges 15–20 - NCT06824649RecruitingPhase 4
Comparing biologics for chronic sinusitis with nasal polyps
This trial compares three different biologic medications (injectable drugs) to see which one works best for people with chronic sinusitis and nasal polyps. If you have moderate to severe symptoms and are considering biologic therapy, this study might help find the best option for you.
Gainesville, FloridaAges 18 years+ - NCT06820593Recruiting
Asthma care with technology for kids and families
This study tests whether a sensor that tracks inhaler use can help children ages 4–17 with persistent or uncontrolled asthma. It aims to make managing asthma at home easier for caregivers.
Chicago, IllinoisAges 4 years+ - NCT06818019RecruitingPhase 4
Stopping dupilumab when asthma is well controlled
This study tests whether it’s safe to stop taking dupilumab once your severe asthma has been well controlled for a long time. If you join, you may stop the medication and be closely monitored to see if your asthma stays under control.
Toulouse, CHU de ToulouseAges 18 years+ - NCT06819228RecruitingPhase 1
Lighted antibody imaging in head and neck cancer surgery
This trial tests a special fluorescent dye attached to panitumumab, a cancer-targeting antibody, to help surgeons see tumor tissue more clearly during head and neck cancer surgery. The goal is to improve removal of all cancer cells while sparing healthy tissue.
Nashville, TennesseeAges 18 years+ - NCT06819462Recruiting
Inhaled colistin to prevent ventilator pneumonia in brain injury patients
This trial tests whether giving an inhaled antibiotic called colistin can prevent pneumonia in patients with brain injuries who are on ventilators. If effective, it could reduce lung infections and improve recovery.
Nanjing, JiangsuAges 18–80 - NCT06821113Recruiting
COVID-19 prevention program for Latino day laborers
This trial tests a program adapted for Latino day laborers to help prevent COVID-19. It aims to see if the program works for people who look for work at street corners.
Houston, TexasAges 18 years+ - NCT06817421RecruitingPhase 4
Pneumococcal vaccine for children with severe malnutrition
This study tests whether giving the pneumococcal vaccine during hospitalization for severe malnutrition can help prevent infections. It may help protect your child from serious illness.
DiliAges 6 months–4.9 years - NCT06822543RecruitingPhase 2
A new treatment for lung cancer that has spread to the brain
This trial tests a combination of three drugs (datopotamab deruxtecan, carboplatin, and pembrolizumab) for people with a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to the brain and has not been treated before. The goal is to see if this combination can shrink tumors in the brain and elsewhere.
Fortaleza, CearáAges 18 years+ - NCT06825078Recruiting
Lung MRI with synthetic CT for monitoring lung nodules
This study tests whether using an MRI combined with a special type of CT scan can effectively monitor lung nodules over time. It may help people at high risk for lung cancer avoid repeated radiation from regular CT scans.
PessacAges 55–74 - NCT06818266RecruitingPhase 3
Tocilizumab for severe chest crisis in sickle cell disease
This trial tests if the drug tocilizumab can help treat acute chest syndrome, a serious lung complication of sickle cell disease. It is for people with sickle cell disease who are hospitalized and need oxygen or breathing support. The study compares tocilizumab to a placebo to see if it speeds up recovery.
ParisAges 2 years+ - NCT06817590RecruitingPhase 1
Nucleoside therapy for telomere disorders
This trial tests a nucleoside therapy (dC/dT) for people with telomere biology disorders, which cause premature aging and problems like low blood counts, lung or liver issues. The goal is to see if the treatment can help manage these symptoms.
Boston, MassachusettsAges 1–70 - NCT06815289Recruiting
MR-guided radiation for hard-to-treat central lung tumors
This trial tests a specialized radiation therapy that uses daily MRI scans to precisely target lung tumors located near the windpipe or esophagus. It aims to improve treatment accuracy while reducing side effects.
ZurichAges 18 years+ - NCT06819969Recruiting
Long-term lung health in Canadian vapers and smokers
This study compares lung function and exercise capacity among different groups: people who vape, people who smoke cigarettes, and people who do neither. It aims to understand how vaping devices affect lungs over time.
Edmonton, AlbertaAges 12 years+ - NCT06815250Recruiting
Boosting maternal vaccine knowledge and uptake: The InTroDuce-Programme
This trial tests a programme to help pregnant women learn about and get flu and Tdap vaccines. It aims to increase vaccination rates and improve health for mothers and babies.
Bandar Baru Bangi, SelangorAges 18 years+ - NCT06824961Recruiting
Comparing 3 vs 5 second pauses during CPR for cardiac arrest
This trial is testing whether increasing the pause in chest compressions from 3 to 5 seconds during CPR helps improve breathing support and the chance of restarting the heart. It involves adults who had a cardiac arrest outside the hospital and were treated with a mechanical compression device called LUCAS.
Amsterdam, North HollandAges 16 years+ - NCT06819592RecruitingPhase 3
Preventing early lung infections after severe brain injury
This study tests whether giving an antibiotic (ceftriaxone) early after a severe brain injury can prevent lung infections caused by the breathing machine (ventilator). It is for adults in the ICU who recently started on a ventilator due to a brain emergency.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT06816966Enrolling by invitationPhase 2
Chemo-immunotherapy with split radiation for extensive-stage lung cancer
This trial tests a combination of chemotherapy, immunotherapy, and a special type of radiation given in split sessions for people with extensive-stage small cell lung cancer. The goal is to see if this approach can help control the cancer better.
Fuzhou, FujianAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.