Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06554613RecruitingPhase 2
Olanzapine with first-line immunotherapy for advanced lung cancer trial
This trial tests whether adding the drug olanzapine to standard first-line immunotherapy (with or without chemotherapy) can help people with advanced lung cancer that does not have an EGFR mutation. It aims to improve treatment outcomes and quality of life.
Nanchang, JiangxiAges 18–75 - NCT06554327Recruiting
Rapid test for lung infection in ICU patients on a ventilator
This trial uses a rapid test (PCR) to check for bacteria in your lung fluid, so doctors can pick the right antibiotics faster. It's for ICU patients on a breathing machine who may have a lung infection.
ReimsAges 18 years+ - NCT06563544Recruiting
Two ventilator settings for asthma and COPD patients
This study compares two different ways of delivering breaths from a ventilator for people with severe asthma or COPD. The goal is to see which method might be better for your lungs.
Rotterdam, South HollandAges 18–100 - NCT06563388RecruitingPhase 3
SABR for limited metastatic cancer (ID-COMET trial)
This study tests a precise radiation technique called SABR to treat cancer that has spread to a few spots. It aims to see if this approach can help control the cancer better than usual treatment, especially for lung, prostate, colorectal, or other solid tumors with limited spread.
Buffalo, New YorkAges 1 year+ - NCT06563999RecruitingPhase 2
Study of new drugs for stage III lung cancer with rare gene changes
This trial tests whether giving treatment before surgery (neoadjuvant therapy) can help people with stage III lung cancer that has certain rare gene changes. The goal is to see if this approach can shrink the tumor enough to allow surgery.
Guangzhou, GuangdongAges 18–75 - NCT06560255RecruitingPhase 3
Fish oil in pregnancy to prevent childhood asthma
This study tests if taking fish oil during pregnancy can help lower the risk of childhood asthma. If you have low omega-3 levels, you may be randomly assigned to receive fish oil or a placebo.
Gentofte MunicipalityAges 18–45 - NCT06566898Recruiting
Tracking antibiotic resistance in pneumonia patients
This study uses advanced genetic testing to monitor antibiotic-resistant bacteria in people with pneumonia. It aims to understand how resistance develops and improve treatment choices.
Shanghai, Shanghai MunicipalityAges Any age - NCT06560554Enrolling by invitation
Fermented diet for long COVID microbiome health
This study tests whether eating fermented foods (like yogurt, kimchi, or sauerkraut) can improve gut health and ease symptoms in people with long COVID. You'll log your food on your phone and follow a fermented diet for a period of time.
Rochester, MinnesotaAges 18 years+ - NCT06554353Recruiting
Breathing and exercise tests for shortness of breath
This study looks at how well two breathing tests work for people who have shortness of breath. You will do a breathing test and an exercise test to help doctors better understand your symptoms.
Rochester, New YorkAges 18 years+ - NCT06556433Recruiting
Smoking Cessation Trial with Family Support and Financial Incentives
This study tests whether offering financial rewards to both you and a family member can help you quit smoking. You will be asked to quit smoking, and both you and your nominated family member can earn payments for meeting certain milestones.
Anchorage, AlaskaAges 18 years+ - NCT06556797Recruiting
A study to better understand shortness of breath using a CO2 test
This trial looks at whether a new way of measuring carbon dioxide (CO2) in the blood can help doctors quickly understand why a patient is short of breath. It is for adults who come to the emergency room with trouble breathing, and it involves doing an extra analysis on a blood sample that would be taken anyway.
BobignyAges 18 years+ - NCT06564896Recruiting
Comparing sleep apnea treatments (CPAP vs alternatives)
This trial compares different positive airway pressure (PAP) machines to see which works best for people with moderate to severe sleep apnea. If you have been diagnosed but haven't used a CPAP yet, this study may help find the best option for you.
Cheras, Kuala LumpurAges 18 years+ - NCT06557928Enrolling by invitation
Study of body and mind changes in the Tibetan plateau
This study looks at how healthy people's bodies and minds adapt when they travel to the high-altitude Tibetan plateau. It aims to help understand the changes and find ways to support people working there.
BeijingAges 18–50 - NCT06554522RecruitingPhase 4
Testing CPAP for Premature Babies with Breathing Problems
This trial tests a breathing support method called CPAP for premature babies with breathing problems in Africa. It may help your baby get better oxygen and avoid more invasive treatments.
BanguiAges 1 hour–1 day - NCT06566443RecruitingPhase 1
Honokiol for early-stage lung cancer before surgery
This trial tests a natural compound called honokiol in people with early-stage non-small cell lung cancer who are scheduled for surgery. The goal is to see if honokiol can help shrink or control the tumor before it is removed.
Houston, TexasAges 18 years+ - NCT05227547Recruiting
Study of lung cell changes in smokers and lung disease
This study looks at specific lung cells (called alveolar cells) to understand how smoking and chronic lung disease may change them. You may be invited if you are having lung surgery and can safely take part.
CréteilAges 18 years+ - NCT06076005Recruiting
Advanced Lung Cancer at First Diagnosis Study
This study collects information about people with advanced lung cancer at the time they are first diagnosed. It aims to understand the disease better and may help with future treatments.
RomaAges 18 years+ - NCT06276530Recruiting
Lung surgery: large incision vs. robotic approach and breathing
This study compares how different types of lung surgery (a large incision vs. robotic-assisted small cuts) affect your posture and breathing. It aims to help doctors choose the best approach for recovery.
ParisAges 18 years+ - NCT06322329Recruiting
RealMove Lung: Tracking tumor motion with MRI
This study uses a special MRI scan to measure how your lung tumor moves during breathing. The information may help doctors plan more precise radiation treatment (SBRT) for lung cancers located in the lower part of the lung.
StockholmAges 18 years+ - NCT06321133Recruiting
Weaning babies off high-flow oxygen for bronchiolitis
This trial tests whether babies with bronchiolitis who have been on a high-flow nasal cannula (a breathing tube) for at least 12 hours can safely stop it. It aims to find a better way to wean babies off this breathing support.
JoensuuAges birth–1 year - NCT04300062Recruiting
Rebiopsy of lung cancer after treatment no longer works
This trial studies patients with lung cancer whose disease has continued to grow despite immunotherapy. It involves taking a new tissue sample (a rebiopsy) to help doctors understand what changed during treatment and guide next steps.
Boulogne-BillancourtAges 18 years+ - NCT06513091Recruiting
National lung transplant recipient registry study
This study collects information from all lung transplant recipients in the United States to track their health and outcomes over time. It helps doctors learn how to improve care for people who have had a lung transplant.
Phoenix, ArizonaAges Any age - NCT06499363Recruiting
Treprostinil for pulmonary hypertension in newborns
This study collects information on how well a medicine called treprostinil works and how safe it is for newborn babies with pulmonary hypertension (high blood pressure in the lungs). It is for babies who have already received this treatment as part of their regular care.
BronAges Up to 10 months - NCT06538636Recruiting
Improving lung cancer screening for Veterans
This study is testing a new way to find Veterans who might benefit from yearly lung cancer screening. It uses a computer model to estimate your personal benefit, even if you don't fit the usual screening guidelines.
Bedford, MassachusettsAges 50–80
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.