Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06800339RecruitingPhase 1
Immunotherapy and radiation before surgery for lung cancer
This trial tests combining chemotherapy, immunotherapy, and a low dose of radiation before surgery for people with non-small cell lung cancer that is borderline resectable (can potentially be removed but is close to nearby structures). It aims to see if this approach can shrink the tumor enough to allow successful surgery.
Baltimore, MarylandAges 18 years+ - NCT06800586Recruiting
Air pollution and health: new early warning signs
This study looks for new early warning signs (biomarkers) of how air pollution affects lung and blood health. It is for people with COPD, lung cancer, or leukemia who have never smoked much, as well as for healthy hospital workers.
Bologna, BolognaAges 18 years+ - NCT06801327Recruiting
Comparing two breathing therapies for bronchiectasis
This trial tests whether a new device called Simeox works better than standard chest physical therapy for people with bronchiectasis (widened airways that trap mucus). It compares how well each method clears mucus from the lungs.
Bologna, BolognaAges 18 years+ - NCT06801366Recruiting
Video clips to help diagnose sleep apnea in children
This study tests if video clips recorded at home can help diagnose obstructive sleep apnea in children, possibly reducing the need for an overnight hospital sleep test. It may be a good fit if your child is between 2 and 18 years old, has been referred for a sleep study, and you have a smartphone or tablet.
Edmonton, AlbertaAges 2–18 - NCT06801522RecruitingPhase 2/Phase 3
Nasal spray comparison during breathing tube placement
This trial compares two nasal medications (adrenaline and xylometazoline) to see which one reduces bleeding better when placing a breathing tube through the nose. It may help people undergoing planned mouth or jaw surgery.
Karachi, SindhAges 18–60 - NCT06802003Recruiting
Predicting COPD flare-ups with wearable devices
This study tests whether a wearable device and a smartphone app can predict when your COPD will flare up. It uses AI to spot early warning signs, so you might get help sooner.
Montreal, QuebecAges 40 years+ - NCT06803095Recruiting
Walking with a dog for tinnitus relief in sleep apnea
This study tests whether walking with a dog can help reduce tinnitus complaints in people who have mild sleep apnea and are overweight. It aims to see if this simple, enjoyable activity can improve your symptoms.
Dokki, Giza GovernorateAges 30–45 - NCT06803524RecruitingPhase 4
10-year follow-up after a single pertussis shot
This study checks on people who got a single dose of a whooping cough vaccine about 10 years ago in a previous study. Researchers want to see how well the vaccine is still working and if it is still safe.
Bangkok Noi, Bangkok MetropolisAges Any age - NCT06805409Recruiting
Ultrasound test for kidney risk in ARDS patients
This study tests whether a special ultrasound of the veins (VExUS) can help predict kidney injury in people with severe breathing problems who are on a breathing machine and receiving medicine to support their blood pressure.
Créteil, Val de MarneAges 18–100 - NCT06805825RecruitingPhase 1
Study of NN3201 for advanced cancers with c-Kit
This trial tests a new drug, NN3201, that targets a protein called c-Kit found on some cancer cells. It may be an option for people with certain advanced solid tumors, including GIST, small cell lung cancer, or other c-Kit-positive cancers, who have already tried standard treatments or cannot take them.
Ann Arbor, MichiganAges 18 years+ - NCT06806280Recruiting
Breathing after robotic hysterectomy for endometrial cancer
This study looks at how your breathing changes after a robotic-assisted hysterectomy for endometrial cancer. It aims to help doctors understand recovery and improve care.
GothenburgAges 18 years+ - NCT06807840Recruiting
Flu infection study at Penn Medicine
This study looks at how people's immune systems respond to the flu. If you have a positive flu test at a Penn Medicine location and are 18 or older, you may be able to join.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06807983Recruiting
Lung and heart ultrasound for breathing trouble in older adults
This trial tests whether using lung and heart ultrasound (LuCUS) can help emergency doctors better diagnose and treat shortness of breath in patients over 65. It aims to improve care for older adults with severe breathing problems.
ToulouseAges 65 years+ - NCT06808074RecruitingPhase 4
Inhaled amikacin to prevent pneumonia in cirrhosis patients on ventilators
This trial tests whether inhaling an antibiotic called amikacin can prevent ventilator-associated pneumonia in patients with severe liver disease (cirrhosis) who are on a breathing machine. If you or your loved one is in the ICU with liver issues and needs a ventilator, this study may help reduce the risk of a serious lung infection.
Hyderabad, TelanganaAges 18 years+ - NCT06808464Recruiting
Heart rate changes during sleep in severe sleep apnea
This study looks at how your heart rate changes during sleep in people with severe sleep apnea compared to healthy people. It uses a simple overnight recording to measure your nervous system activity.
LilleAges 18–64 - NCT06808997Recruiting
Study on breathing support decisions for very early preterm babies
This study looks at how doctors decide when to remove the breathing tube (extubation) from extremely preterm babies born before 28 weeks of pregnancy. It aims to understand what affects breathing outcomes and could help improve care for these tiny infants.
AmiensAges 1 minute–5 months - NCT06809309Recruiting
Ventilation during in-hospital cardiac arrest study
This trial tests different methods of giving breaths (ventilation) to adults who have a cardiac arrest while in the hospital. It aims to find which approach works best to improve survival.
AabenraaAges 18 years+ - NCT06810323Recruiting
Oxygen therapy study for COPD patients
This study tests a long-term oxygen therapy program for people with COPD who already use continuous oxygen at home. The goal is to see if regular at-home oxygen use improves breathing and quality of life over time.
Charlottesville, VirginiaAges Any age - NCT06810375RecruitingPhase 3
Nerve Blocks for Pain After Video-Assisted Lung Surgery
This trial tests two different numbing shots (nerve blocks) to see which one works better for pain after video-assisted lung surgery. One block is placed near the spine, and the other is between the ribs. The goal is to find the best way to keep you comfortable after surgery.
Washington D.C., District of ColumbiaAges 18–90 - NCT06810544RecruitingPhase 1/Phase 2
Study of TNG456 for tumors with MTAP loss
This trial tests a new drug called TNG456, alone or with another drug (abemaciclib), for people whose tumors have lost the MTAP gene. It aims to see if the combination can shrink tumors or slow their growth.
Scottsdale, ArizonaAges 18 years+ - NCT06810609RecruitingPhase 2
Immunochemotherapy, surgery, and durvalumab for stage III lung cancer
This trial tests a combination of immunotherapy, chemotherapy, and either surgery or radiation for people with stage IIIA or IIIB non-small cell lung cancer. The goal is to see if adding the drug durvalumab after standard treatment helps control the cancer better.
Freiburg im Breisgau, Baden-WurttembergAges 18–74 - NCT06810934RecruitingPhase 1/Phase 2
New COVID-19 vaccine study for those with prior mRNA vaccines
This study tests a new type of COVID-19 vaccine that is designed to train your immune system to make stronger, longer-lasting protection. You may be able to join if you are 40–64, have already had at least two doses of a mRNA COVID-19 vaccine (Pfizer or Moderna) more than 4 months ago, and are generally healthy.
Los Angeles, CaliforniaAges 40–64 - NCT06811389Recruiting
Peer support program for hypersensitivity pneumonitis
This study tests a program that pairs you with a peer coach (a trained person with lived experience) to help you manage hypersensitivity pneumonitis through education, support, and gentle physical activity. It's designed to see if this kind of support helps people feel better and stay active.
New York, New YorkAges 18–100 - NCT06814340RecruitingPhase 3
CPAP on ECMO for severe lung failure
This trial is for people with severe lung failure (ARDS) who are already on a life-support machine called VV-ECMO. It tests whether adding a special breathing tube (CPAP) can help their lungs heal better.
BobignyAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.