Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06784791RecruitingPhase 2
Amivantamab before surgery for EGFR-mutant lung cancer
This trial tests a new drug, amivantamab, given before surgery for people with a specific EGFR-mutated lung cancer. It aims to shrink tumors and improve surgical outcomes, and may be combined with standard chemotherapy in some patients.
HasseltAges 18 years+ - NCT06785272RecruitingPhase 3
Magnesium for children with asthma in the ER
This trial tests if giving magnesium sulfate through an IV helps children with moderate to severe asthma attacks in the emergency department. If your child is between 2 and 17 years old and still has trouble breathing after three puffs of standard asthma medicine, this study may be an option.
Calgary, AlbertaAges 2–17 - NCT06785337RecruitingPhase 2/Phase 3
Inhaled nitroglycerin for COPD flare-ups
This trial tests if breathing in a medicine called nitroglycerin can help people with severe COPD and high blood pressure in their lungs. It aims to see if this treatment improves breathing during a COPD exacerbation.
Haram, Giza GovernorateAges 18 years+ - NCT06785571RecruitingPhase 2/Phase 3
Pain relief study for ICU patients on a ventilator
This study tests a painkiller called nalbuphine for ICU patients on a breathing machine. It aims to see if it controls pain as well as or better than usual care, with fewer side effects.
Wuhan, HubeiAges 18–80 - NCT06786468Recruiting
Early palliative care for advanced lung cancer
This study tests whether adding early palliative care from a specialist improves well-being for people starting treatment for advanced non-small cell lung cancer. It compares standard cancer care alone to standard care plus early palliative care.
BangkokAges 18 years+ - NCT06788093Recruiting
Reducing antibiotic overuse with decision support
This trial tests a tool to help doctors decide when antibiotics are truly needed for lung infections like bronchitis or pneumonia. It may help you avoid unnecessary antibiotics and their side effects.
Oakland, CaliforniaAges 6 months–17 years - NCT06788366Recruiting
AI tool to predict outcomes in metastatic lung cancer
This trial is testing whether artificial intelligence can help predict how well people with advanced non-small cell lung cancer (NSCLC) respond to immunotherapy or chemo-immunotherapy. If you have stage IV NSCLC and have started this treatment, your data may help build a better prediction tool.
MilanAges 18 years+ - NCT06788470RecruitingPhase 1/Phase 2
Stem cell therapy for severe lung disease in premature babies
This trial tests whether umbilical cord stem cells can help premature babies with severe bronchopulmonary dysplasia (a chronic lung disease) who still need a breathing tube after standard hormone treatment. The goal is to see if it is safe and improves their lung condition.
Hangzhou, ZhejiangAges 8 months+ - NCT06789172RecruitingPhase 1
New drug OKN4395 with or without pembrolizumab for solid tumors
This trial tests a new oral drug called OKN4395, which targets a COX2-related immune pathway, alone or with the immunotherapy pembrolizumab, in people with advanced solid tumors. It may be an option if you have certain types of cancer that have stopped responding to other treatments.
Beverly Hills, CaliforniaAges 18 years+ - NCT06789770Recruiting
Nasal vs mouth breathing during drug-induced sleep
This study compares how breathing through the nose versus mouth affects sleep, using both natural and medication-induced sleep. It may help people with sleep apnea understand their breathing patterns better.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06790082RecruitingPhase 2
FAPI PET scan to diagnose pleural mesothelioma
This trial tests if a newer type of PET scan (FAPI PET) can better diagnose pleural mesothelioma than a standard FDG PET scan. If you have a suspicious spot in your lung lining and need a biopsy, this study may help improve how we find and track this cancer.
Aalborg, Region North JutlandAges 18 years+ - NCT06790108Recruiting
AI guidance for learning chest ultrasound
This study tests an AI tool that helps doctors learn to perform endoscopic ultrasound (EUS) better. If you need an EUS to check for problems in your chest, you may be able to join and help improve training for future doctors.
Changsha, HunanAges 18–80 - NCT06790797Recruiting
Predicting immunotherapy success in chest cancers
This study is for people with lung or esophageal cancer who will receive immunotherapy (drugs that help your immune system fight cancer). The researchers want to find markers in your blood and tumor that can predict how well the treatment will work.
Suzhou, JiangsuAges 18–80 - NCT06790875Recruiting
Comparing two ventilator settings for lung health in ARDS
This study tests two methods of adjusting a ventilator to see which one may better protect the lungs of patients with ARDS. It will help doctors learn how to set the machine to reduce strain on the lungs.
Wuhan, HubeiAges 18–80 - NCT06791668Recruiting
Magnesium treatment for severe preeclampsia
This study looks at different ways to give magnesium sulphate to women with severe preeclampsia to find the best treatment plan.
CairoAges 18 years+ - NCT06792045Recruiting
Predicting tongue blockage during sleep in children
This study uses a special camera during sleep to see if the tongue is blocking the airway in children with sleep-disordered breathing. It may help doctors better understand why some children still have trouble breathing after tonsil surgery.
BrusselsAges 6–17 - NCT06792214RecruitingPhase 4
Testing if antivirals prevent long-term heart problems after COVID-19
This study tests whether two antiviral medications, Paxlovid and Veklury (remdesivir), can reduce the risk of long-term heart and blood vessel problems after a COVID-19 infection. It is for adults recently hospitalized with COVID-19 who are not currently on oxygen therapy.
Kingston, OntarioAges 18 years+ - NCT06793813RecruitingPhase 2
Study of cadonilimab for advanced lung cancer
This trial tests a new drug called cadonilimab for people with advanced non-squamous non-small cell lung cancer that has gotten worse after treatment with immunotherapy and chemotherapy. The goal is to see if it helps control the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06793800Recruiting
Ear nerve stimulation to improve breathing after stroke
This study tests whether a gentle nerve stimulation device placed on your ear can improve your breathing after a stroke. It's for people who had a first stroke 1 to 3 years ago and are otherwise generally healthy (no heart, lung, or ear problems).
IstanbulAges 40–80 - NCT06794125Recruiting
Higher radiation dose for chest tumors
This trial tests if giving a higher dose of radiation to tumors in the chest (lungs or nearby areas) can better control symptoms or prevent them from getting worse. It is for people who need palliative radiation—treatment aimed at easing discomfort or slowing tumor growth, not curing the cancer.
Kelowna, British ColumbiaAges 18 years+ - NCT06795971Recruiting
Comparing oxygen methods for hypoxemic respiratory failure
This trial compares three ways of giving extra oxygen to people with low blood oxygen levels: a face mask with continuous pressure, a noninvasive ventilator, or high-flow oxygen through the nose. The goal is to see which method helps people avoid needing a breathing tube.
Nanjing, JiangsuAges 18 years+ - NCT06796894Recruiting
Asthma symptoms, breathing, and frailty study
This study looks at symptoms, breathing problems, and frailty in people with allergic or eosinophilic asthma. It aims to understand how these factors relate to each other.
Ankara, StateAges 35–75 - NCT06797206Recruiting
CF in pregnancy and child health study
This study follows women with cystic fibrosis (CF) during pregnancy and after birth, and checks on their babies and young children. The goal is to learn more about how CF affects pregnancy and child development.
LondonAges Any age - NCT06798077Recruiting
Chronic Lung Disease and Multiple Health Issues Study
This study follows people with chronic airway diseases like COPD, asthma, or bronchiectasis who were recently hospitalized for a worsening of their condition. It aims to understand how these diseases affect overall health and other medical problems over time.
Beijing, Beijing MunicipalityAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.