Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,644 recruiting studies in this area right now.
By phase
- Not applicable4,309
- Phase 2852
- Phase 1471
- Phase 3427
- Phase 1/Phase 2310
- Phase 4209
- Phase 2/Phase 366
Top conditions
- Lung Cancer426
- Asthma194
- Non Small Cell Lung Cancer188
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD142
- Breast Cancer111
- COVID-19107
- Pulmonary Hypertension101
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Interstitial Lung Disease79
- Pneumonia79
- Cystic Fibrosis78
- Chronic Obstructive Pulmonary Disease (COPD)73
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama172
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas91
- Pennsylvania81
- Illinois72
Recruiting studies6,644 total
- NCT07633184Recruiting
Lung Ultrasound to Predict Breathing Problems in Premature Babies
This study uses ultrasound images of the lungs to see if doctors can predict which very premature babies will develop bronchopulmonary dysplasia (BPD)—a chronic lung condition common in extremely premature infants. The goal is to identify at-risk babies early so they can receive targeted treatment.
ModenaAges Up to 7 months - NCT07633288RecruitingPhase 2
AP1189 Safety and Efficacy for Severe Respiratory Viral Infection
This trial tests whether an experimental drug called AP1189, added to standard hospital care, can help people hospitalized with severe breathing problems from viruses like COVID-19, flu, or RSV. The goal is to see if it reduces the need for mechanical ventilation or other life support.
Mostar, Herzegovina-Neretva CantonAges 18 years+ - NCT07633626Recruiting
Vortioxetine for thinking problems from ALK lung cancer treatment
This trial tests whether a medication called vortioxetine can help improve memory, focus, and thinking problems caused by lorlatinib, a drug used to treat ALK-positive lung cancer. You would take vortioxetine alongside your current cancer treatment to see if it helps your brain function.
BogotáAges 18 years+ - NCT07634861Recruiting
AI Assistant Tool for Reading Chest CT Scans
This study tests whether an AI assistant can help radiologists (doctors who read X-rays and scans) interpret chest CT scans more accurately. Radiologists will use the AI tool and provide feedback on whether it's helpful.
ShanghaiAges 18 years+ - NCT07635446Recruiting
Relaxation techniques for COPD anxiety, sleep, and fatigue
This study tests whether two relaxation methods—Laura Mitchell's technique and Benson relaxation—can help people with COPD feel less anxious, sleep better, and have more energy. You would learn and practice these techniques over the course of the study.
Lahore, Punjab ProvinceAges 40–60 - NCT07636252Recruiting
Testing lung cancer drugs on your fluid sample
This study collects fluid that builds up around your lungs (pleural effusion) during a drainage procedure you already need. Researchers test how different drugs affect your cancer cells in the lab to help predict which treatments might work best for you.
Ramat Gan, IsraelAges 18 years+ - NCT07637448RecruitingPhase 2
EGFR-targeted therapy plus immunotherapy for advanced lung cancer
This trial tests combining two types of cancer drugs—a targeted pill that attacks a specific mutation in your lung cancer cells, followed by an immunotherapy injection when your tumor stops shrinking. The goal is to see if this combination works better than standard treatment alone.
Guangzhou, GuangdongAges 18 years+ - NCT07637474Recruiting
Immune System and Lung Cancer Response to Immunotherapy
This study looks at how your immune system works in non-small cell lung cancer and whether it predicts how well you'll respond to a type of immunotherapy called anti-PD-1/PD-L1 drugs. Researchers will study your tumor tissue to understand why some patients benefit more than others.
Rome, RomeAges 18 years+ - NCT07638345Recruiting
AI-powered weight management for teens with diabetes or asthma
This study tests a smartphone app that uses artificial intelligence to help families manage weight and health for teenagers (ages 12–21) with Type 1 Diabetes or asthma. The app is designed to be personalized to each family's needs and may help improve overall health outcomes.
SevilleAges 18 years+ - NCT07641023RecruitingPhase 1/Phase 2
CAR-NK Cell Therapy for Advanced Lung Cancer
This study tests a new type of immune cell therapy (CAR-NK cells) designed to recognize and attack lung cancer cells that have spread or stopped responding to standard treatments. The goal is to see if this approach can shrink tumors and help patients live longer.
Shenzhen, GuangdongAges 18–75 - NCT07641309Recruiting
Health Program for Diabetes, Lung, or Heart Disease
This study measures how a health improvement program helps people with type 2 diabetes, chronic lung disease, or heart disease. Researchers will track your health before and after you participate in the program offered by your local municipality.
FrederiksværkAges 18 years+ - NCT07641413Recruiting
How lungs and heart change over a lifetime of health
This study follows healthy adults over decades to understand how lung and heart function naturally change with age. Researchers will measure your breathing and heart health to help them spot early warning signs of disease in future patients.
San Francisco, CaliforniaAges 24–68 - NCT07645027Recruiting
Breathing exercises to improve lung function after neck spinal cord injury
This study tests whether special breathing exercises using a handheld device can help people recover lung strength after a recent cervical (neck-level) spinal cord injury. The exercises are done during in-patient rehabilitation and may help you breathe better and improve your overall recovery.
Lahore, Punjab ProvinceAges 18–38 - NCT07645534RecruitingPhase 1
Testing a New Antiviral Medicine Formulation in Healthy Adults
This study compares two versions of an antiviral medicine called Ingavirin to see how your body processes them and whether they are safe. Researchers will give you the medicine on an empty stomach and after eating to understand how food affects how your body absorbs it.
Saint PetersburgAges 18–45 - NCT07646106RecruitingPhase 1
Testing THE-0504 in Advanced Solid Tumors
This Phase 1 trial tests a new drug called THE-0504 in patients with advanced solid tumors (like lung, colon, pancreas, stomach, or breast cancer) that have not responded to standard treatments. The study aims to find the right dose and understand how well and safely the drug works.
Rome, LazioAges 18 years+ - NCT07646288Recruiting
Visual Feedback Breathing Training After Lung Cancer Surgery
This study tests whether using visual feedback (like watching a screen) during breathing exercises helps lung cancer patients recover better after surgery to remove part of a lung. The goal is to see if this type of guided breathing practice improves how well your lungs work after the operation.
Ankara, AltındağAges 18–75 - NCT07646587RecruitingPhase 2
Safety Study of WIN378 for Moderate-Severe COPD
This study tests a new drug called WIN378 in people with moderate-to-severe COPD (chronic lung disease). It will check if the drug is safe and how the body processes it, which may help improve breathing and reduce flare-ups.
Miami Lakes, FloridaAges 40–80 - NCT07647094RecruitingEarly Phase 1
Chemotherapy plus immunotherapy for advanced squamous lung cancer
This trial tests a combination of three drugs—two chemotherapy medications (carboplatin and nab-paclitaxel) plus an immunotherapy drug (serplulimab)—as a first-line treatment for advanced squamous cell non-small cell lung cancer. The goal is to see if this combination works better than standard treatment and is safe for patients who haven't received prior systemic cancer treatment.
Quzhou, ZhejiangAges 18–75 - NCT07647497Recruiting
Heart Imaging to Predict Outcomes in Pulmonary Embolism
This study uses ultrasound images of your heart to see how well the right side is working in people who have a blood clot in the lungs. The goal is to better predict which patients might be at higher risk and need more intensive care.
SohagAges 18 years+ - NCT07647575Recruiting
Salt Water Inhalation for Nontuberculous Mycobacterial Lung Disease
This trial tests whether breathing salt water vapor through a home nebulizer machine helps people with a specific type of lung infection (nontuberculous mycobacteria). The goal is to see if this simple treatment can improve breathing and reduce symptoms.
TaipeiAges 18 years+ - NCT07648082Recruiting
Understanding Breathlessness in Lung Disease
This study explores how people experience and perceive breathlessness, whether they have a known lung condition or are healthy. Researchers want to understand breathlessness better to potentially improve how it's managed and treated.
Leicester, LeicestershireAges 18–100 - NCT07649629Recruiting
Blood test to help diagnose advanced lung cancer
This study tests whether a blood test (liquid biopsy) can help doctors better understand your lung cancer and plan your treatment. You'll have a blood sample taken alongside standard biopsies to see if the blood test provides useful information about your cancer.
Roma, RMAges 18 years+ - NCT07650084RecruitingPhase 3
Testing BLU-5937 for hard-to-treat chronic cough
This 24-week study tests whether a new medicine called BLU-5937 can help adults whose chronic cough hasn't improved with standard treatments. Chronic cough that lasts a year or longer can seriously affect quality of life, and this trial explores whether this drug might provide relief.
Leshan, SichuanAges 18–80 - NCT07650227RecruitingPhase 3
Raphamin for treating acute bronchitis in adults
This study tests whether a medicine called Raphamin can safely and effectively treat acute bronchitis (a chest infection with cough) in adults. Raphamin may help reduce cough and breathing problems in the early stages of this condition.
AramilAges 18–64
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,644 recruiting pulmonology studies from the U.S. registry right now, out of 10,689 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.