Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06232447Recruiting
Menthol smoking and inflammation study
This study looks at how menthol cigarettes affect inflammation and smoking habits. It uses a smartphone app to track your experiences and may help find better ways to help people quit.
North Chicago, IllinoisAges 21–85 - NCT06179069RecruitingPhase 1
Study of ZL-1310 for small cell lung cancer
This trial tests a new drug called ZL-1310, alone or with other treatments, for people with small cell lung cancer that has spread (extensive-stage). It aims to see if ZL-1310 can help shrink tumors or slow the disease.
Duarte, CaliforniaAges 18 years+ - NCT06321133Recruiting
Weaning babies off high-flow oxygen for bronchiolitis
This trial tests whether babies with bronchiolitis who have been on a high-flow nasal cannula (a breathing tube) for at least 12 hours can safely stop it. It aims to find a better way to wean babies off this breathing support.
JoensuuAges birth–1 year - NCT06322719Recruiting
Comparing two blades for intubation in the ICU
This trial tests which blade (hyperangulated or Macintosh) works better when doctors use a video laryngoscope to place a breathing tube in intensive care patients. It may help improve how intubation is done in the ICU.
Santiago de Compostela, A CoruñaAges 18–90 - NCT06286891Recruiting
Frailty and lung function after pulmonary endarterectomy
This study looks at how frailty, physical ability, and lung function change in people who have had surgery to remove blood clots from the lungs (pulmonary endarterectomy). It aims to help doctors better understand recovery after this procedure.
São Paulo, São PauloAges 18 years+ - NCT06276010Recruiting
Nafamostat mesilate for blood thinning in ECMO patients
This trial tests a medicine called nafamostat mesilate to prevent blood clots in patients who need ECMO (a machine that helps your heart and lungs) after heart surgery. It may offer a safer way to thin the blood compared to standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06236347Enrolling by invitation
Rural COPD study using e-visits for smokers
This study tests whether online e-visits can help rural smokers without COPD quit smoking. It uses smartphone tools and mailed devices to track progress remotely.
Charleston, South CarolinaAges 40 years+ - NCT06182748Recruiting
Physical activity and lung scarring
This study tests if a supervised exercise program, 3 times a week, helps people with lung scarring (fibrosing interstitial lung disease). It may improve your breathing and quality of life.
Bobigny, Seine Saint DenisAges 18 years+ - NCT06310187Recruiting
Little cigar study for daily cigarette smokers
This study looks at how certain chemicals from little cigars affect the body. It may help researchers understand health risks. You must be a daily cigarette smoker who has never smoked little cigars.
Hershey, PennsylvaniaAges 21–65 - NCT06296277Recruiting
Breathing machine use during surgery
This study looks at how a breathing machine is used during surgery. It is for adults who need help breathing while under general anesthesia for their operation.
Alessandria, ItalyAges 18 years+ - NCT06246760Recruiting
Exercise and fitness in healthy adults
This study looks at how breathing, body composition, and heart-lung fitness vary between people who exercise regularly and those who don't. You may qualify if you are generally healthy and can do a treadmill or bike test until you are too tired to continue.
Madrid, Comunity of MadridAges Any age - NCT06317324Recruiting
SBRT vs. surgery for lung cancer with lobe spread
This study compares two treatments—stereotactic body radiation (SBRT) and surgery—for people whose non-small cell lung cancer has spread into the tissue between the lobes of the lung. The goal is to see which treatment leads to better long‑term results for this specific type of cancer.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06267118RecruitingPhase 3
Saline vs Adrenaline for Bronchiolitis in the PICU
This trial compares two breathing treatments—hypertonic saline and adrenaline—for children with severe bronchiolitis in the pediatric intensive care unit. The goal is to see which works better to help them breathe easier.
Nowshera, KPKAges 1 month–2 years - NCT06003569Recruiting
Reducing asthma attacks in kids at school
This trial tests a program to help children with poorly controlled asthma in rural Colorado schools. It aims to reduce asthma attacks and improve daily life for kids who often have symptoms.
Ault, ColoradoAges 5–12 - NCT06240637Recruiting
Telemonitoring for starting home ventilator
This study tests whether using a remote monitoring system (telemonitoring) helps people adjust better to a new home ventilator. It is for people with long-term breathing problems who are starting a ventilator for the first time.
BarcelonaAges 18 years+ - NCT06162286RecruitingPhase 3
Comparing two antibiotics for pneumonia in adults
This trial tests a new antibiotic (omadacycline) compared to a standard one (moxifloxacin) for adults with community-acquired pneumonia. The goal is to see if the new drug is as safe and effective.
BeijingAges 18 years+ - NCT06026735Recruiting
Lung cancer with brain spread: a surgical study
This trial looks at people with non-small cell lung cancer that has spread to the brain or the membranes around the brain. It aims to learn more about patients who are already scheduled for brain surgery, such as removing a tumor or placing a drain.
TaipeiAges 20–90 - NCT06042621Enrolling by invitation
Improving communication in the ICU for patients, families, and staff
This study looks at how doctors, nurses, and other healthcare team members talk with patients and their families in the intensive care unit (ICU). It aims to improve understanding and support for everyone involved.
Chicago, IllinoisAges 18 years+ - NCT06024993Recruiting
Studying dead space in breathing machines during surgery
This trial looks at a part of breathing machines called 'dead space' in adults having planned surgery under general anesthesia. The goal is to learn more about how the lungs work during controlled breathing.
Edegem, AntwerpAges 18–70 - NCT05971719Recruiting
Testing an air “sniffer” using aerosol glycerine during lung surgery
This trial checks whether a new system can detect and pinpoint tiny air leaks during lung transplant surgery. It uses a glycerine mist during the operation, which may help surgeons find leaks and repair them sooner.
MontrealAges 18 years+ - NCT06037733Recruiting
Focused radiation to main tumor after chemo-immunotherapy for lung cancer
This trial is for people with advanced non-small cell lung cancer whose tumors responded well to initial chemo-immunotherapy. Instead of giving full chest radiation, doctors will only target the main tumor to see if it can prevent regrowth with fewer side effects.
Wuhan, HubeiAges 18–75 - NCT06083870RecruitingPhase 1
Oba01 for advanced lung cancer that has progressed
This trial tests a new drug called Oba01 for people with advanced non-small cell lung cancer (NSCLC) that has gotten worse after other treatments. It targets a protein called DR5 found on cancer cells.
ShanghaiAges 18–75 - NCT06015256Recruiting
Natural killer cells in severe asthma patients
This study looks at immune cells called natural killer cells in people with severe asthma. Researchers want to see how these cells are different in people whose asthma is well-controlled, not well-controlled, or flaring up, compared to healthy volunteers without asthma.
MarseilleAges 18 years+ - NCT05971810Recruiting
Oral cleaning and nutrition support around surgery for older adults
This trial studies whether cleaning the mouth before and after major surgery, plus special nutrition support, can lower the risk of breathing complications in older adults. It may help patients who are at higher risk for lung problems around the time of general anesthesia.
Shijiazhuang, HebeiAges 65 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.