Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,346 recruiting studies in this area right now.
By phase
- Not applicable4,049
- Phase 2834
- Phase 1456
- Phase 3421
- Phase 1/Phase 2309
- Phase 4212
- Phase 2/Phase 365
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer184
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1993
- Colorectal Cancer90
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis76
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama178
- Arizona153
- Florida120
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,346 total
- NCT03787056Recruiting
Blood test marker study in many cancer types
This study measures a blood marker called progastrin (at diagnosis and during treatment) to see how well it predicts response or outcomes. It may help doctors choose or monitor treatment more precisely for several cancer types.
BronAges 18 years+ - NCT03269630Recruiting
Pulmonary hypertension biobank for heart-lung blood samples
This study collects and stores health information and possibly blood samples from people being evaluated for pulmonary hypertension or related autoimmune conditions. It helps researchers learn more about these illnesses and may support future studies.
New Orleans, LouisianaAges 18 years+ - NCT05033691Recruiting
Osimertinib plus early brain radiation versus osimertinib alone
This trial tests whether starting focused radiation to brain spots early (called SRS) along with osimertinib works better than taking osimertinib alone. It is for people with lung cancer that has an EGFR mutation and has not yet caused major brain symptoms.
JerusalemAges 18–120 - NCT04200079Recruiting
Long-term follow-up study for people with COPD
This study follows people with COPD over time to better understand their lung health and how it changes. It may help researchers and doctors learn what factors affect breathing and long-term outcomes.
Kingston, OntarioAges 40–85 - NCT05053802RecruitingPhase 2
Microwave tumor ablation plus immunotherapy for multiple lung cancers
This Phase 2 trial studies whether combining microwave ablation (a procedure to destroy lung tumors) with an immune checkpoint inhibitor can control multiple early lung cancers safely. It also aims to see how well the immune treatment helps after ablation, in people whose cancers have not spread.
Shanghai, Shanghai MunicipalityAges 18–79 - NCT04335773Recruiting
Study of COVID-19 in hospitalized children
This study looks at children (ages 0 to 18) who are in the hospital with suspected COVID-19. It aims to understand what factors affect outcomes and how the immune system responds.
LørenskogAges Up to 18 years - NCT04316364RecruitingPhase 3
New immunotherapy plus chemo for resectable lung cancer
This Phase 3 trial studies whether an immunotherapy drug (SHR-1316) added to standard chemotherapy helps people live longer or delay cancer returning after surgery. It focuses on people with resectable non-small cell lung cancer (NSCLC) that has not been treated before.
Beijing, Beijing MunicipalityAges 18–70 - NCT05102825Recruiting
Lung MRI registry to track breathing health
This study builds a lung imaging registry using MRI pictures to learn how breathing health looks and changes. It may help researchers understand lung problems and how well different people can complete breathing-related MRI scans.
Vancouver, British ColumbiaAges birth–99 years - NCT05104788RecruitingPhase 2
Icotinib plus chemotherapy before surgery for EGFR lung cancer
This trial studies how well a targeted medicine (icotinib) combined with chemotherapy works before surgery for certain EGFR-mutated lung adenocarcinoma. The goal is to shrink or control the tumor and make surgery more effective.
BeijingAges 18–75 - NCT03906617RecruitingPhase 4
Pain-relief shots for lung surgery: three drug options compared
This study compares different pain-relief medications given during lung surgery to see which one controls pain better. It may help people have less post-surgery pain after robotic wedge resection or lobectomy.
Camden, New JerseyAges 18–90 - NCT05178277Recruiting
Alpha-1 antitrypsin deficiency registry study
This study collects health information from people who have alpha-1 antitrypsin deficiency. It may help doctors better understand the condition and improve care over time.
Prague, Czech RepublicAges Any age - NCT04558450Recruiting
Study how COVID-19 affects blood vessel stiffness and aging
This study looks at how having COVID-19 may affect your blood vessels over the following months. It may help doctors understand long-term “vascular aging” and who is most at risk, based on how sick you were during your COVID illness.
NancyAges 18 years+ - NCT05134467Recruiting
Protocol-based weaning from the ventilator in ICU patients
This study looks at a step-by-step plan to help patients come off the breathing machine (mechanical ventilator) and checks how well it works. If you’re an ICU patient on the ventilator for at least two days, you may be eligible to follow their protocol.
SeoulAges 19–99 - NCT05172739RecruitingPhase 4
Opioid-free anesthesia during lung surgery for early lung cancer
This study tests whether an opioid-free pain/anesthesia plan during elective lung surgery can reduce surgical “stress” on the body and affect the immune system. You may be eligible if you have early-stage non-small cell lung cancer and are scheduled for a specific type of surgery (VATS lobectomy).
Heraklion, CreteAges 18–80 - NCT05200429Recruiting
Study of long-term effects of CFTR modulator medicines in CF
This observational study follows people with cystic fibrosis (CF) to understand the long-term impact of CFTR modulator medicines. It may help researchers see how these treatments work over time in real life.
Vancouver, British ColumbiaAges Any age - NCT05207852Recruiting
Dexamethasone study for preterm labor lung development
This trial studies how well dexamethasone works and how it behaves in the body when given during preterm labor to help the baby’s lungs mature. You may be able to join if you’re pregnant between 24–36 weeks and are receiving the study treatment per their schedule.
BeijingAges 20–40 - NCT05221372Recruiting
Sampling study for lung cancer patients on targeted pills
This trial collects blood samples from adults with advanced lung cancer that has a specific gene change and who are already taking targeted pill treatment (TKIs). The goal is to learn from these samples and how they relate to the cancer in patients on standard therapy.
RotterdamAges 18 years+ - NCT04791891Recruiting
Study collecting information about low back pain
This study asks adults with low back pain to complete an online questionnaire so researchers can better understand how low back pain affects daily life. Your answers may help build a larger “core dataset” for future research.
Montreal, QuebecAges 18 years+ - NCT02762175Recruiting
Track breathing airway changes after jaw surgery for sleep apnea
This study records how your upper airway changes on scans after a jaw surgery called MMA for obstructive sleep apnea (OSAS). It also looks at how those changes relate to quality of life, which may help doctors better predict who benefits from surgery.
BrugesAges Any age - NCT05270616Recruiting
Robotic or video-assisted lung surgery compared
This trial compares robotic surgery and video-assisted surgery for removing part of the lung (lobectomy or segmentectomy). It may help determine which approach is safer or works better for patients who can safely tolerate minimally invasive surgery.
Jinan, ShandongAges 18–85 - NCT02803242Recruiting
Patient research network for people with lung symptoms
This trial enrolls adults to help build a patient-powered research network for chronic lung disease. If you join, you’ll likely be asked to complete surveys or provide information to help researchers learn how symptoms and health outcomes change over time.
Washington D.C., District of ColumbiaAges 18 years+ - NCT04976296Recruiting
Monitoring minimal residual disease after lung cancer surgery
This study checks whether a special blood/tissue test called MRD (minimal residual disease, meaning tiny leftover cancer signals) can help monitor lung cancer after surgery. It may help doctors spot relapse earlier after your tumor has been fully removed.
Guangzhou, GuangdongAges 18 years+ - NCT01822834Recruiting
Registry for adults with bronchiectasis and non-tuberculosis lung bacteria
This study is a registry that collects health information from adults who have bronchiectasis caused by non-tuberculosis mycobacteria (NTM). It helps researchers better understand this condition and improve future treatments.
Washington D.C., District of ColumbiaAges 18–120 - NCT05289245Recruiting
Registry study for Chinese people with cystic fibrosis
This study keeps a national record of people diagnosed with cystic fibrosis (CF) in China. It aims to better understand CF over time and may help future care by improving how patients are tracked and studied.
Beijing, Beijing MunicipalityAges Any age
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,346 recruiting pulmonology studies from the U.S. registry right now, out of 9,900 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.