Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,290
- Phase 2848
- Phase 1471
- Phase 3423
- Phase 1/Phase 2311
- Phase 4207
- Phase 2/Phase 368
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer170
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome73
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Chinese University of Hong Kong35
- Riphah International University34
Where studies are running
- California390
- Alabama175
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT05950893Recruiting
Testing a device to measure breathing effort on ventilators
This trial checks whether a tool (called PMIvent) can safely and accurately track how hard you are breathing while you are on a ventilator set to “pressure support.” If it works well, it may help clinicians better understand breathing effort during this common type of ventilator care.
BeijingAges 18–85 - NCT05866835Recruiting
Digital mouth guard safety and fit check in boxing or rugby
This study tests a digitalised way of providing or checking an intraoral (mouth) protection device for people who play contact sports like boxing, rugby, or football. It mainly checks whether the protection can be safely used for eligible participants.
BordeauxAges 16–35 - NCT05602662Recruiting
Music to help sedate adults on a breathing machine
This trial looks at whether listening to music can help make “pharmacological sedation” (medicine to help you relax/sleep) easier or more comfortable for adults in the ICU who are on a ventilator (breathing machine). It may help improve comfort during critical care treatment.
Karlstad, Värmland CountyAges 18–100 - NCT05338801Recruiting
Study menthol effects in e-cigarette users
This study tests how menthol in e-cigarettes affects addiction-related feelings and exposure. You may be asked to visit a lab and temporarily stop vaping before each session.
Miami, FloridaAges 21–35 - NCT07785791Recruiting
Enhanced recovery and nutrition after lung cancer surgery
This study looks at how an enhanced recovery program (ERAS) affects nutrition and recovery after lung cancer surgery. It may help improve your post-surgery outcomes.
Bursa, NilüferAges 18–85 - NCT07783971Recruiting
Lung cancer microbiome study
This study looks at the bacteria and other microbes in lung cancer tissue to understand how they might affect the disease. It may help find new ways to treat or manage non-small cell lung cancer.
Chongqing, Liangjiang NewAges 30–80 - NCT07176000Recruiting
Helping tribal members get lung cancer screening
This study tests a program to help people in tribal communities get screened for lung cancer. It may help you get a low-dose CT scan to check for lung cancer early, when it’s easier to treat.
Auburn, WashingtonAges 18 years+ - NCT07124078RecruitingPhase 2
Study of axatilimab for young people with chronic graft-versus-host disease
This study tests a new drug called axatilimab for children and teens with chronic graft-versus-host disease (cGVHD) that hasn't improved with standard treatments. The goal is to see if axatilimab works better than the usual care options. Participants will be randomly assigned to receive either axatilimab or one of several standard treatments.
Duarte, CaliforniaAges 2–17 - NCT07785999Recruiting
Wearable ring sensor for diagnosing sleep apnea in adults
This study tests whether a wearable ring sensor can help diagnose obstructive sleep apnea (a condition where breathing stops during sleep) compared to the standard in-lab sleep test. If you have suspected sleep apnea and are generally healthy, this study might help you get a simpler and more convenient diagnosis.
Pantai Valley, Kuala LumpurAges 18 years+ - NCT07784517Recruiting
Breathing technique for arm performance in volleyball players
This study looks at how a breathing technique called diaphragmatic facilitation affects arm and upper body performance in volleyball players. It may help improve your game by enhancing shoulder and arm function.
IstanbulAges 18–30 - NCT05483491RecruitingPhase 1
TCR cell therapy for select metastatic cancers
This Phase 1 trial tests a personalized immune-cell treatment (TCR-T cells) for certain metastatic cancers. It targets cancers that carry a specific marker and requires patients to have a specific immune-system match, aiming to improve cancer control when standard options were already tried.
New Brunswick, New JerseyAges 18 years+ - NCT07295158Recruiting
Comparing Two Anesthesia Gases for Gallbladder Surgery
This trial compares two different anesthesia gases (sevoflurane vs. desflurane) during laparoscopic gallbladder surgery. It measures how each gas affects the pressure on your lungs, to see which might be safer.
Konya, KonyaAges 18–65 - NCT06765109RecruitingPhase 3
Testing neladalkib for untreated ALK-positive lung cancer
This study tests a new pill called neladalkib to see if it works better than the current standard treatment (alectinib) for people with ALK-positive lung cancer who have not yet received any cancer therapy for advanced disease. It may be a good option if you have ALK-positive NSCLC and have not been treated before.
Glendale, ArizonaAges 18 years+ - NCT07768748Recruiting
Understanding breathing support interactions with your ventilator
This study looks at how well your breathing matches the ventilator when using certain home ventilation machines. It aims to improve how these devices help people with breathing problems.
Schmallenberg, North Rhine-WestphaliaAges 18–80 - NCT07164144Enrolling by invitation
School Ambassadors for Vaccine Education
This trial tests whether training students as vaccine ambassadors can improve vaccine education in schools. It may help increase vaccine knowledge and uptake among students.
Rochester, New YorkAges 5–21 - NCT07155174RecruitingPhase 2
Testing new drug combo for first-line extensive small cell lung cancer
This trial tests a new combination treatment (ABBV-706 plus atezolizumab) as a first option for people with extensive stage small cell lung cancer. It compares this new approach to the usual standard treatment, aiming to see if it works better and has fewer side effects.
New Haven, ConnecticutAges 18 years+ - NCT06580210Recruiting
Seawater spray with essential oils for stuffy nose
This trial tests a seawater and essential oil spray to clear a stuffy nose caused by a cold, sinus infection or allergies. The spray is meant to help you breathe easier without strong medicines.
BayeuxAges 12 years+ - NCT06647953RecruitingPhase 3
Testing a standard approach for pleuropulmonary blastoma, with or without topotecan
This trial compares a standard surgery and chemotherapy plan for type I pleuropulmonary blastoma (PPB) to adding the drug topotecan for types II and III PPB. The goal is to see if the extra drug helps shrink tumors and improve outcomes for children with more advanced disease.
Birmingham, AlabamaAges Up to 21 years - NCT07412262RecruitingPhase 2
Study of chidamide and ivonescimab for advanced lung cancer after immunotherapy resistance
This trial tests a combination of two drugs (chidamide and ivonescimab) for people with advanced non-small cell lung cancer that stopped responding to initial immunotherapy and has a specific protein marker (YAP) at high levels. It aims to see if this new combination can help when standard immunotherapy no longer works.
Guangzhou, GuangdongAges 18 years+ - NCT06987890Recruiting
Geriatric assessment for older adults with lung cancer getting SBRT
This study looks at how a geriatric assessment can help older adults with early-stage lung cancer who are getting a precise type of radiation therapy called SBRT. The goal is to understand their needs and improve care.
Boston, MassachusettsAges 65 years+ - NCT07685522Recruiting
Vibrato clot removal for pulmonary embolism safety study
This trial tests the Vibrato Aspiration System, a device that suctions blood clots from the lungs in people with a recent pulmonary embolism (PE). It aims to see if the procedure is safe and works well for removing clots.
Poznan, Greater Poland VoivodeshipAges 18–75 - NCT07380113RecruitingPhase 4
Comparing two drugs for sleep in dialysis patients with itch
This trial tests if anrikefon or nalfurafine improves sleep quality in people on hemodialysis who have chronic kidney disease-related itching. It aims to find a better treatment for both itch and sleep problems.
Guangzhou, GuangdongAges 18–75 - NCT06683599Recruiting
Oxygen via nasal tube for babies during breathing tube placement
This study tests whether giving extra oxygen through a small tube in the nose during placement of a breathing tube helps young children stay safer. It is for newborns and infants up to about 1 year old who need a breathing tube for surgery or other non-emergency procedures.
Perth, Western AustraliaAges 1 minute–12 months - NCT06804122Recruiting
Exercise rehab for pulmonary arterial hypertension
This trial tests a supervised exercise program for people with pulmonary arterial hypertension (PAH), a type of high blood pressure in the lungs. It aims to see if regular exercise can improve your daily function and quality of life.
Tampere, PirkanmaaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,500 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.