Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,629 recruiting studies in this area right now.
By phase
- Not applicable4,297
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2310
- Phase 4208
- Phase 2/Phase 368
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama174
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas90
- Pennsylvania84
- Colorado71
Recruiting studies6,629 total
- NCT06885905Recruiting
Impact of lung infection on health and well-being
This study looks at how chronic pulmonary aspergillosis (a long-term lung infection) affects your daily life, health, and overall well-being. By joining, you'll help researchers understand what it's like to live with this condition.
DundeeAges 18 years+ - NCT06876766Recruiting
Lung ultrasound to guide antibiotic use in kids with chest infections
This trial tests whether using a lung ultrasound can help doctors decide if antibiotics are needed for children and teens hospitalized with a lower respiratory tract infection. It may reduce unnecessary antibiotic use.
BeirutAges 3 months–18 years - NCT07424014RecruitingPhase 4
Heliox and breathing control during exercise
This trial tests whether a special gas mixture called heliox (helium and oxygen) can help control breathing during exercise. It is for healthy, active adults age 18–40 who exercise regularly and have no major health problems.
Bloomington, IndianaAges 18–40 - NCT06913166Recruiting
Online Quiz on Smoking for Primary School Students
This trial tests if an online quiz game can teach kids about the harms of smoking and improve their attitudes and behaviors towards tobacco. It is for primary 5 and 6 students who can read Chinese and have a device at home.
Hong KongAges 9–13 - NCT03656081RecruitingPhase 3
Treating chronic lung Aspergillus with inhaled and oral antifungals
This study tests whether a combination of inhaled liposomal amphotericin B (Ambisome) plus itraconazole works better for chronic pulmonary aspergillosis (CPA). It may help control long-term Aspergillus lung infection and symptoms.
PoitiersAges 18 years+ - NCT06745869Recruiting
Aerobic and breathing exercises for choir singers
This trial tests whether combining aerobic exercise with special breathing exercises (diaphragmatic) improves singing and breath control in choir members. If you're a chorist with a sedentary lifestyle, you may benefit from this study.
IstanbulAges 25–60 - NCT06907160Recruiting
Chemotherapy plus immunotherapy before lung cancer surgery
This trial tests a combination of chemotherapy and immunotherapy given before surgery for stage II or III non-small cell lung cancer. Doctors will look at biomarkers in your blood and tissue to see how the cancer responds, which could help guide future treatments.
SeoulAges 19 years+ - NCT07326449Enrolling by invitation
CO2 measurement test on exercise bike
This trial checks if a portable device can reliably measure carbon dioxide in your breath while you rest and cycle slowly. It may help understand how your lungs work during light exercise.
LinköpingAges 18–70 - NCT05856136RecruitingPhase 4
Study how opioid exposure affects diaphragm muscle function
This study looks at whether receiving opioids for pain during lower-leg surgery changes how well the diaphragm muscle (the main breathing muscle) works afterward. It compares breathing muscle function in people who do and do not have certain lung conditions.
Rochester, MinnesotaAges 18 years+ - NCT05918783RecruitingPhase 1
Testing a light-activated therapy in peripheral lung tumors
This Phase 1 trial tests padeliporfin, a light-activated medicine, delivered to lung tumors using robotic bronchoscopy. It may help people with small, peripheral lung cancer lesions by targeting the tumor without open surgery.
Baltimore, MarylandAges 18 years+ - NCT06724718Recruiting
Using a smartwatch to detect atrial fibrillation after chest surgery
This trial tests whether a smartwatch can detect atrial fibrillation in people who have had major chest surgery (like lung removal) within the last 48 hours. If successful, this could help catch heart rhythm problems early without extra hospital equipment.
AmiensAges 18 years+ - NCT06682221Enrolling by invitationPhase 3
Resistance training and supplement study for older adults
This study tests whether a resistance training program (like lifting weights) combined with a supplement can improve heart, lung, and metabolic health in older adults. The goal is to find ways to help seniors stay healthier and more active.
Anápolis, GoiásAges 60–85 - NCT03826797Recruiting
Testing breathing pressure signals in serious lung breathing failure
This study looks at how pressure readings from a breathing tube compare with whether non-invasive breathing support fails in people with sudden, severe low oxygen levels. It may help improve how clinicians spot who will need stronger breathing treatment sooner.
ModenaAges 18 years+ - NCT06868836RecruitingPhase 2
Study of a new antibody combination for advanced lung cancer after targeted therapy
This trial tests a new drug (JS207) that targets both PD-1 and VEGF pathways, given alone or with other treatments, for people with advanced non-small cell lung cancer that has a specific gene change and has stopped responding to targeted therapy (TKI). The goal is to see if this combination can help shrink tumors or slow cancer growth.
Guangzhou, GuangdongAges 18–75 - NCT06865326Recruiting
Early detection of CTEPH after pulmonary embolism
This trial is for people who had a pulmonary embolism (a blood clot in the lungs) in the last 3 to 12 months and are still on blood thinners. It aims to find early signs of a serious condition called CTEPH (chronic blood clots in the lungs) so treatment can start sooner.
BrnoAges 18 years+ - NCT05873504Recruiting
Testing vibration devices to clear mucus from airways
This trial compares different vibratory devices that help loosen and clear mucus from the lungs. It may help by showing which device works best and is safest for people who need airway clearance therapy.
Chicago, IllinoisAges 18 years+ - NCT06851936Recruiting
Help quitting tobacco for cancer survivors and their caregivers
This study tests a program to help people with a history of cancer and their family caregivers quit using tobacco or nicotine products. You may help researchers learn what works best for supporting quitting in this group.
Gainesville, FloridaAges 18 years+ - NCT06844331Enrolling by invitation
Ultrasound for lung disease testing
This study tests if ultrasound can help evaluate patients with fibrosing interstitial lung disease (a type of lung scarring). It aims to see if ultrasound is a useful tool for checking your condition.
Odense, Southern DenmarkAges 18 years+ - NCT06838806Recruiting
A blood test to help diagnose risky lung nodules
This trial uses a simple blood test to look at certain genetic markers that may help doctors decide if a lung nodule is cancerous or not. It is designed for people who have a lung nodule that needs further testing like a biopsy or surgery.
TaipeiAges 20 years+ - NCT05884645Recruiting
Video-guided breathing tube placement study in the OR
This study tests video-guided placement of a breathing tube through the nose or mouth during a procedure. It may help improve how safely and smoothly intubation is done using video technology.
CopenhagenAges Any age - NCT03954574Recruiting
Check blood flow changes in lungs during exercise testing
This study measures how blood moves through your lungs and heart while you exercise, using standard heart-lung pressure measurements. It may help doctors better understand unexplained breathing trouble or suspected pulmonary hypertension and improve how testing and care are guided.
Phoenix, ArizonaAges 18 years+ - NCT07625956Enrolling by invitationPhase 4
Nicotine Pouches as a Smoking Substitute Study
This study tests whether nicotine pouches (small pouches you place in your mouth) can help smokers quit or reduce combustible cigarettes. You'll use the pouches as a substitute and attend visits in Charleston, SC to see if this approach works better with new support strategies.
Charleston, South CarolinaAges 21 years+ - NCT06823622Recruiting
Digital transition care for teens with asthma or transplants
This trial tests a digital program to help teenagers with asthma, allergies, or organ transplants move from pediatric to adult healthcare. It aims to see if online support works as well as in-person visits.
Gothenburg, Vastra GotalandsregionenAges 15–20 - NCT06245317Recruiting
New ventilation method for children having laparoscopic surgery
This trial compares a special ventilation method (PCV-VG) to standard care during laparoscopic surgery in children. It aims to see if it helps them breathe better during the procedure.
Asyut, Asyut GovernorateAges 1–8
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,629 recruiting pulmonology studies from the U.S. registry right now, out of 10,546 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.