Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,629 recruiting studies in this area right now.
By phase
- Not applicable4,297
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2310
- Phase 4208
- Phase 2/Phase 368
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama174
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas90
- Pennsylvania84
- Colorado71
Recruiting studies6,629 total
- NCT06820034RecruitingPhase 2/Phase 3
Smoking cessation program for LGBTQ+ adults in Arkansas, Oklahoma, Texas
This trial tests whether a program that includes nicotine replacement therapy and volunteering in the LGBTQ+ community helps people quit smoking. You need to live in Arkansas, Oklahoma, or Texas, identify as LGBTQ+, and be ready to quit within 30 days.
Oklahoma City, OklahomaAges 18–100 - NCT06679257Recruiting
Liquid biopsy for lung transplant damage classification
This study tests a simple blood test (liquid biopsy) to detect and classify damage to a transplanted lung. It aims to find signs of rejection or injury earlier, which could help doctors treat problems sooner.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT06814951Recruiting
Breathing & movement technique after heart bypass surgery
This study tests a special breathing and movement technique called the Thoraco-abdominal Rebalance Method to see if it helps people recover faster after heart bypass surgery.
Porto Alegre, Rio Grande do SulAges 35 years+ - NCT06770179Enrolling by invitation
Lung breathing maneuver for kids during surgery
This study tests a special breathing maneuver (ultrasound-guided lung recruitment) during surgery to see if it helps prevent small areas of lung collapse in children. It may help kids with longer surgeries keep their lungs open and working better afterward.
IstanbulAges 1–14 - NCT07296848Enrolling by invitation
Health communications for adults who smoke occasionally
This study tests health messages for people who smoke some days but not every day. The goal is to help you think about your smoking and consider quitting.
Lexington, KentuckyAges 18 years+ - NCT06805357Recruiting
Lung opening during chest therapy on a breathing machine
This study tests a method to improve lung function during chest physical therapy for patients on a breathing machine. It may help clear mucus and make breathing easier.
CréteilAges 18–100 - NCT05754034Recruiting
High-flow oxygen versus standard oxygen in hospitalized adults
This study tests whether a high-flow oxygen device works better than the usual (standard) oxygen for people admitted to the hospital with low blood oxygen. The goal is to see if high-flow oxygen can help you breathe easier and improve oxygen levels faster.
KijabeAges 18 years+ - NCT07559123Recruiting
Imaging to predict who benefits from chemoimmunotherapy before lung cancer surgery
This study uses CT scan images to help doctors predict which patients with resectable lung cancer will benefit most from receiving chemoimmunotherapy (a combination of chemotherapy and immunotherapy) before surgery. The goal is to personalize treatment planning and improve outcomes.
SeoulAges 18 years+ - NCT06777056Recruiting
AI for spotting lung bruises on chest X-rays after chest injury
This trial tests whether AI can help doctors find lung bruises (contusions) on chest X-rays, using high-resolution CT scans as the reference. If you came to the ER with a blunt chest injury and had both an X-ray and a CT scan within 48 hours, you may be able to help improve how we detect injuries.
BolognaAges 18 years+ - NCT07141264RecruitingPhase 2
Maintenance therapy for extensive-stage small cell lung cancer
This trial tests a combination of two drugs (adebrelimab and etoposide capsules) as maintenance therapy for people with extensive-stage small cell lung cancer who have not progressed after initial treatment. It may help extend the time before the cancer grows back.
Xi'an, ShannxiAges 18–75 - NCT01571986Recruiting
Improving non-invasive breathing support
This study is looking at ways to improve non-invasive ventilation, which is breathing support given without a breathing tube. You may be invited if you’re already receiving this kind of support and you agree to take part.
MilanAges 18–99 - NCT07445035Recruiting
Robotic leg brace to help walking while on a breathing machine
This study tests whether walking with a robotic leg brace (exoskeleton) can help people who are on a breathing machine get better faster. It is for adults in the intensive care unit who can sit, stand with help, and have no major leg or heart problems.
New Taipei CityAges 45–65 - NCT06735976Recruiting
Safety and effectiveness of LOBO device for PAVM treatment
This study tests a new device (LOBO™) to block abnormal blood vessels in the lungs called PAVMs. It is for people with HHT or similar conditions, and the device is placed into the vessel to reduce the risk of stroke or bleeding. You may be able to join if you have a suitable PAVM that is large enough and you are not taking blood thinners.
Chapel Hill, North CarolinaAges 14 years+ - NCT06719284Recruiting
Improving breathing support in newborns on special ventilators
This trial is studying how to use a special breathing machine (high frequency oscillatory ventilation) in newborns. The goal is to improve the settings for better breathing support.
LondonAges 5 months–1 year - NCT06722365Recruiting
Fetal lung study using ultrasound
This study uses a special ultrasound to look at your baby's lung development in the last weeks of pregnancy. It may help doctors learn more about how healthy lungs grow before birth.
Madison, WisconsinAges 18–45 - NCT06713187Recruiting
Interleukin-23 study in lupus and lung disease
This trial looks at a protein called interleukin-23 in people with lupus, especially those who also have lung inflammation (interstitial lung disease). The goal is to understand more about this protein's role and possibly find new ways to help.
SohagAges 18–60 - NCT06420999Recruiting
Diaphragm weakness after breathing support in the ICU
This study looks at how common diaphragm weakness is in people who have been on breathing support in the ICU. If you are coming off that support, researchers want to learn if your diaphragm strength affects your recovery.
ParisAges 18 years+ - NCT06703814Recruiting
Protective breathing support during robot surgery
This trial tests a special way of breathing support during robot-assisted surgery to protect your lungs. It's for people who are at higher risk of lung problems after surgery.
Innsbruck, TyrolAges 18 years+ - NCT05922202Recruiting
Studying how frailty affects outcomes in COPD
This study looks at whether frailty (how weak or vulnerable someone is) changes the risk of heart-related events and death in people with COPD. It may help doctors better predict who is at higher risk and tailor care.
ModenaAges 40 years+ - NCT06684392Recruiting
Breathing muscle training to help remove tracheostomy tube
This trial tests whether a special breathing exercise program can help people with a tracheostomy (a tube in the throat to help breathing) get the tube removed faster. It is for adults who are awake and can cooperate.
Rancagua, Región del Libertador General Bernardo O’HigginsAges 18 years+ - NCT07727681RecruitingPhase 4
Statins to Prevent Atrial Fibrillation After Lung Surgery
This trial tests whether taking a statin before and after lung surgery can prevent a common heart rhythm problem called atrial fibrillation (AFib). If you are 60 or older and having a lung segment or lobe removed, this study may help you avoid AFib after your operation.
BeijingAges 60 years+ - NCT06701253Recruiting
Ultrasound study of the upper airway
This study uses an ultrasound to look at the upper airway in adults having planned surgery with general anesthesia and a breathing tube. It may help doctors understand airway anatomy better.
Ioannina, EpirusAges 18–99 - NCT05924087Recruiting
Treatment study for narrowing of the windpipe after tracheotomy
This trial tests an interventional treatment for narrowing of the windpipe (tracheal stenosis) that happened after a percutaneous (through-skin) tracheotomy. It may help improve breathing and reduce problems caused by the narrowing.
NiddaAges 18 years+ - NCT06693700Recruiting
Using an air quality monitor to help make your home smoke-free
This study tests whether an indoor air quality monitor can help people keep their homes smoke-free. It is for MSK patients who currently smoke and want to reduce smoke exposure indoors.
Basking Ridge, New JerseyAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,629 recruiting pulmonology studies from the U.S. registry right now, out of 10,546 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.