Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,629 recruiting studies in this area right now.
By phase
- Not applicable4,297
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2310
- Phase 4208
- Phase 2/Phase 368
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama174
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas90
- Pennsylvania84
- Colorado71
Recruiting studies6,629 total
- NCT06970639RecruitingPhase 3
Study comparing new targeted drug plus chemo vs osimertinib for lung cancer with brain tumors
This trial tests a new targeted therapy called furmonertinib combined with chemotherapy against the current standard osimertinib for people with a specific type of non-small cell lung cancer (NSCLC) that has spread to the brain. It aims to find a better treatment option for patients whose cancer cells have a common EGFR mutation.
Guangdong, GuangzhouAges 18 years+ - NCT06972784Recruiting
Heart and lung health study at Xiangya Hospital
This study looks at how heart and lung function are related over time. You may be able to join if you have had both a heart test (like an echo) and a lung test (like a breathing test) within one year of each other, and if your medical records are complete.
Changsha, HunanAges Any age - NCT06547710Recruiting
Surgery for lung cancer that has spread to the lining of the lung
This trial tests if removing the main lung tumor can help patients whose cancer has spread to the lining of the lung (M1a stage) but not to other organs. It is for people who have not had any prior treatment for lung cancer.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05838183Recruiting
Test treatment in people with lung disease and sleep apnea
This trial is studying how a treatment may work for adults who have interstitial lung disease or obstructive sleep apnea. It likely involves sleep testing so the team can measure breathing and sleep patterns.
TianjinAges 18–80 - NCT07192939RecruitingPhase 2
Testing HRS-9813 for progressive pulmonary fibrosis
This trial tests a new drug called HRS-9813 for people with pulmonary fibrosis (scarring in the lungs) that continues to worsen. It looks at whether the drug can slow down the disease compared to a placebo.
Beijing, Beijing MunicipalityAges 21 years+ - NCT05837052RecruitingPhase 2
Serplulimab plus chemo after initial treatment for lung cancer
This Phase 2 study looks at how safe and effective serplulimab (an immune medicine) combined with chemotherapy is when used as a “conversion” plan—first shrinking lung cancer, then trying to remove the main tumor with surgery. It may help some people who are not initially good candidates for surgery or focused radiation to become eligible after treatment.
Hangzhou, ZhejiangAges 18–75 - NCT07436949RecruitingPhase 1/Phase 2
Study of BBT002 for chronic sinusitis with nasal polyps and asthma
This study tests a new drug called BBT002 in healthy people and in patients with chronic sinusitis and nasal polyps, with or without asthma. It aims to see if the drug is safe and effective for reducing symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT05854654Recruiting
Testing leak detection during lung transplant surgery
This trial studies a way to spot and treat air leaks during lung transplant surgery. It may help surgical teams reduce leak-related problems during and after the transplant.
Montreal, QuebecAges 18 years+ - NCT05654922RecruitingPhase 3
Prevent lung transplant airways scarring with ARINA-1
This Phase 3 trial tests ARINA-1 to slow or prevent worsening lung transplant scarring in the breathing tubes (bronchiolitis obliterans). It may help people who are showing early decline in lung function but are not yet at advanced disease.
Phoenix, ArizonaAges 18–75 - NCT06953843RecruitingPhase 2
Radiation and Immunotherapy for Advanced Lung Cancer
This trial tests a combination of radiation and immunotherapy to see if it can make the immune system attack cancer throughout the body in people with advanced lung cancer that has spread to many places. It's for those whose cancer does not have certain genetic changes and who have not had uncontrolled brain metastases.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT05841472RecruitingPhase 2
Camrelizumab plus chemo for advanced lung cancer without EGFR or ALK
This Phase 2 trial tests whether the immunotherapy drug camrelizumab, combined with pemetrexed and carboplatin, can work better as first treatment for advanced lung cancer that has no EGFR or ALK gene changes. You may be able to join if you have measurable disease, good enough organ function, and meet other safety rules for immune treatment.
AnamAges 19–80 - NCT07656155Enrolling by invitation
Digital health study for high-risk ICU patients on ventilators
This study looks at patients who are in the ICU, on a breathing machine, and have a long-term health condition. It aims to use digital tools to better understand these high-risk patients and improve their care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06878703RecruitingPhase 3
Dexmedetomidine vs midazolam for preterm babies on a ventilator
This study compares two sedative medicines, dexmedetomidine and midazolam, to see which one helps preterm babies on a ventilator breathe on their own sooner. Your baby may be eligible if they were born very early and need medicine to relax while on the breathing machine.
ParisAges Up to 7 months - NCT07598136Recruiting
How e-cigarette flavors affect smoking habits
This study looks at whether different flavors in e-cigarettes help smokers quit or reduce regular cigarettes. You'll use e-cigarettes with different flavors while researchers track your smoking habits through a smartphone app.
Maitland, FloridaAges 21–65 - NCT06561620RecruitingPhase 4
Befotertinib after surgery for early-stage lung cancer
This trial tests a pill called befortinib for people with early-stage lung cancer who have had surgery. It aims to lower the chance of the cancer coming back. You might qualify if your tumor had certain high-risk features and you still have cancer DNA in your blood after surgery.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07050056RecruitingPhase 2
Immunotherapy plus radiation before lung cancer surgery
This study tests whether giving a combination of the immunotherapy drug tislelizumab and chest radiation before surgery can improve outcomes for people with early-stage, operable lung cancer. The goal is to find out if this approach helps shrink the tumor and makes surgery more effective.
Yangzhou, JiangsuAges 18–70 - NCT06942715Recruiting
Clean cooking study for Cambodian families
This study gives clean-burning induction stoves to families in Cambodia that don't already have one. It aims to see if switching to electric cooking improves health and the environment.
Kampong Speu, Kampong Speu ProvinceAges 18 years+ - NCT06941948Recruiting
Sleep and immune system in lung cancer
This study looks at how sleep problems affect your body's immune response to lung cancer. It aims to find links between sleep and the tumor environment, which could help improve treatment.
ShanghaiAges 18–70 - NCT06719258Recruiting
Trial on heated humidifiers for breathing tubes
This trial studies how heating and adding moisture to the air breathed through a breathing tube (called a heated humidifier) affects patients in intensive care. It focuses on people who need the breathing tube for a longer time or special protective settings.
Québec, QuebecAges 18 years+ - NCT06935695Recruiting
Routine or waiting after airway stent placement
This study compares two approaches after placing a stent in the main breathing passages: either routine follow-up with a camera exam (bronchoscopy) or watchful waiting unless symptoms arise. It aims to see which strategy works better for patients.
New York, New YorkAges 18 years+ - NCT07744074Recruiting
Carbon-ion radiation for large chest tumors
This trial tests a new type of radiation using carbon ions to treat large tumors in the chest that have come back or not responded to prior treatments. It aims to see if this therapy is safe and effective for people who have few options.
Hangzhou, ZhejiangAges 18 years+ - NCT06932718Recruiting
Smoking cessation program for Hong Kong workers
This study tests a workplace program to help people in Hong Kong quit smoking. It includes support through instant messaging and check-ins over 12 months.
Hong KongAges 18 years+ - NCT06930183Recruiting
Awake vs. asleep for lung surgery recovery
This trial compares being awake with numbing medicine in your back (epidural) versus being fully asleep (general anesthesia) for lung surgery. It aims to see which approach leads to a smoother recovery with fewer complications.
CairoAges 18–75 - NCT06930443Recruiting
Oxygen use and organ injury after heart-lung bypass surgery
This trial looks at how oxygen is used during heart surgery that uses a heart-lung machine, and whether low oxygen levels can lead to organ damage. It may help doctors better understand how to protect patients during surgery.
Uppsala, SwedenAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,629 recruiting pulmonology studies from the U.S. registry right now, out of 10,546 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.