Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,347 recruiting studies in this area right now.
By phase
- Not applicable4,045
- Phase 2834
- Phase 1458
- Phase 3422
- Phase 1/Phase 2311
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1988
- Colorectal Cancer88
- NSCLC87
- Chronic Obstructive Pulmonary Disease85
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California383
- Alabama175
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York111
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,347 total
- NCT06777771Recruiting
Reformer Pilates for first-time pregnant women
This trial tests if Reformer Pilates (a type of exercise using a special machine) helps first-time pregnant women stay healthy. If you are in your first pregnancy and between 11 and 22 weeks along, this may be a good fit for you.
Izmir, KonakAges 18–35 - NCT06189495RecruitingPhase 2
Study of Genakumab for lung scarring from connective tissue disease
This study tests a new injected medication (Genakumab) for people with connective tissue disease-related lung scarring. It aims to see if it helps stabilize or improve lung function safely.
Beijing, Beijing MunicipalityAges 18–75 - NCT06667167RecruitingPhase 2
First-line Keytruda + chemo then Keytruda + Trodelvy for SCLC
This trial tests a two-step treatment for extensive-stage small cell lung cancer: first, chemotherapy combined with Keytruda (an immunotherapy), followed by Keytruda plus Trodelvy (another targeted drug). The goal is to see if this combination helps people live longer and keeps the cancer under control.
Jerusalem, IsraelAges 18–99 - NCT07473700RecruitingPhase 2
Study of TX000045 for lung scarring and high blood pressure in the lungs
This trial tests a new medicine called TX000045 for people who have both lung scarring (interstitial lung disease) and high blood pressure in the lungs (pulmonary hypertension). It aims to see if the drug can help improve breathing and daily function.
Phoenix, ArizonaAges 18–80 - NCT07476313Enrolling by invitation
Testing a new home sleep system for moderate to severe sleep apnea
This study tests a home sleep testing system called SleepView+ in people who have already been scheduled for an overnight sleep lab study. If you have moderate to severe obstructive sleep apnea, this device might offer a more convenient way to monitor your sleep at home.
Redwood City, CaliforniaAges 12 years+ - NCT07476287RecruitingPhase 2
Study of PF08634404 plus chemo for transformed small cell lung cancer
This trial tests a new study drug (PF08634404) combined with standard chemotherapy for people whose non-small cell lung cancer has changed into a more aggressive form called small cell lung cancer. It hopes to improve outcomes by targeting the cancer in two ways.
Duarte, CaliforniaAges 18 years+ - NCT07480213RecruitingPhase 1/Phase 2
CAR-NK cell therapy for relapsed small cell lung cancer
This trial tests a new type of immunotherapy called dual-target CAR-NK cells for people with small cell lung cancer that has returned or not responded to treatment. The treatment uses your own immune cells, modified in a lab, to better recognize and attack cancer cells.
Shenzhen, GuangdongAges 18–75 - NCT06758271Recruiting
Long-term study of avacopan for vasculitis
This study looks at the long-term safety and effectiveness of avacopan in people with certain types of vasculitis (GPA or MPA). It may help doctors understand how well the medicine works over time.
Multiple LocationsAges Any age - NCT06780826Recruiting
Atezolizumab plus chemo for extensive-stage small cell lung cancer
This trial tests whether adding the immunotherapy drug atezolizumab to standard chemotherapy helps people with extensive-stage small cell lung cancer. It is for those who have not had treatment for this stage yet.
ShanghaiAges 18 years+ - NCT07480616Recruiting
Indonesian asthma breathing exercise for stable asthma
This study tests a special Indonesian breathing exercise program for adults with stable asthma. It aims to see if this routine helps improve your lung function and asthma control.
JakartaAges 18–65 - NCT07472738Recruiting
Studying treatable traits in chronic airway diseases
This trial is studying people with chronic lung conditions, like COPD or asthma, to find treatable traits. It also includes healthy volunteers for comparison, to better understand what makes these diseases different and how to personalize treatment.
Beijing, Beijing MunicipalityAges 20–75 - NCT07479277Recruiting
Progel to reduce air leaks after lung surgery
This trial tests whether a special gel (Progel Platinum) can reduce air leaks that sometimes happen after lung cancer surgery. It is for people having minimally invasive surgery to remove the upper or lower lobe of the lung.
Candiolo, TorinoAges 18–99 - NCT07477158Recruiting
Comparing two lung cancer surgeries for recovery and quality of life
This study compares two types of lung cancer surgery—removing just the tumor section (segmentectomy) or the whole lobe (lobectomy)—done through small cuts (minimally invasive). The goal is to see which approach leads to better daily living and recovery for early-stage lung cancer patients.
Madrid, MadridAges 18 years+ - NCT07476703Recruiting
Extended study on the SCAPIS Stockholm reexamined group
This trial studies data and samples from people already taking part in the main SCAPIS reexamination study in Stockholm. It looks for new findings to help understand heart and lung health.
StockholmAges 56–74 - NCT07476495Recruiting
Study on lung cancer spread
This study looks at how lung cancer spreads in people with early-stage non-small cell lung cancer. It may help doctors better understand the disease and improve treatment.
Bologna, BolognaAges 18 years+ - NCT07474220Recruiting
Study of SLC25A48 in COPD
This study measures a protein called SLC25A48 in people with COPD (a lung condition that makes breathing hard) and in healthy people to learn if it plays a role in the disease.
New Taipei CityAges 18 years+ - NCT07476274Recruiting
Study of pneumonia after heart bypass surgery
This trial looks at pneumonia that happens in the hospital after coronary artery bypass surgery. It aims to understand who is at risk and how to better prevent or treat it.
Tomsk, Tomsk OblastAges 18 years+ - NCT07478809Recruiting
Long-term study of RATIONALE-307 trial participants
This study looks back at people who took part in the RATIONALE-307 trial for a type of lung cancer called squamous non-small cell lung cancer. It aims to learn more about their health outcomes over time by only including those who were still alive when the original trial ended.
BeijingAges Any age - NCT07477197Recruiting
Heart Institute Biobank for Adult Congenital Heart Disease
This study collects blood and tissue samples and health information from adults with or at risk for congenital heart disease or related heart conditions. It aims to help researchers better understand these conditions and improve future treatments.
Cincinnati, OhioAges 16 years+ - NCT06684418Recruiting
AI to find hidden cancer spread in early lung cancer
This trial uses artificial intelligence to predict if early-stage lung cancer has spread to nearby lymph nodes. It aims to help doctors make better treatment decisions for patients with stage 1 lung cancer.
ShanghaiAges 18 years+ - NCT06779799Recruiting
Study of vocal cord lesions in autoimmune disease patients
This study examines vocal cord lesions, like 'bamboo' nodes, that cause voice changes (dysphonia) in people with autoimmune diseases such as lupus or rheumatoid arthritis. It aims to better understand and characterize these lesions to improve diagnosis and treatment.
BrestAges 18 years+ - NCT06783101Recruiting
Smart Inhaler for Teens with Intellectual Disabilities and Asthma
This study tests a 'smart' inhaler that tracks when and how your child uses their asthma medicine. The goal is to help teens with intellectual or developmental disabilities manage asthma better at home.
Los Angeles, CaliforniaAges 10–17 - NCT06785571RecruitingPhase 2/Phase 3
Pain relief study for ICU patients on a ventilator
This study tests a painkiller called nalbuphine for ICU patients on a breathing machine. It aims to see if it controls pain as well as or better than usual care, with fewer side effects.
Wuhan, HubeiAges 18–80 - NCT06024993Recruiting
Studying dead space in breathing machines during surgery
This trial looks at a part of breathing machines called 'dead space' in adults having planned surgery under general anesthesia. The goal is to learn more about how the lungs work during controlled breathing.
Edegem, AntwerpAges 18–70
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,347 recruiting pulmonology studies from the U.S. registry right now, out of 9,965 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.