Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,347 recruiting studies in this area right now.
By phase
- Not applicable4,045
- Phase 2834
- Phase 1458
- Phase 3422
- Phase 1/Phase 2311
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1988
- Colorectal Cancer88
- NSCLC87
- Chronic Obstructive Pulmonary Disease85
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California383
- Alabama175
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York111
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,347 total
- NCT06786468Recruiting
Early palliative care for advanced lung cancer
This study tests whether adding early palliative care from a specialist improves well-being for people starting treatment for advanced non-small cell lung cancer. It compares standard cancer care alone to standard care plus early palliative care.
BangkokAges 18 years+ - NCT06675942Recruiting
Comparing two breathing techniques for patients with excess mucus on ventilators
This trial compares two chest therapy methods to help clear mucus in ICU patients who are on a breathing machine. If you have a lot of mucus and are on a ventilator, this study may test which technique works better.
BeijingAges 18 years+ - NCT06401512Recruiting
Digital follow-up for COPD patients in primary care
This trial tests a digital follow-up program for people with COPD who live at home. It aims to help manage your condition with remote support from your healthcare team.
Bergen, NorwayAges 35–80 - NCT06783582Recruiting
Motivational interviewing by phone for COPD support
This study tests whether motivational interviewing (a supportive talk therapy) via smartphone can help people with COPD manage their condition better. You would have online interview sessions to help you stay motivated and improve your breathing health.
ErzurumAges 18 years+ - NCT06071013RecruitingPhase 1/Phase 2
Nintedanib plus EGFR inhibitor for EGFR-mutated lung cancer
This trial tests a combination of two drugs—nintedanib and an EGFR inhibitor—for people with EGFR-mutated non-small cell lung cancer whose cancer has stopped responding to their first EGFR inhibitor treatment. The goal is to see if adding nintedanib can help control the cancer again.
TaichungAges 20–70 - NCT07464730Recruiting
High-flow nasal oxygen after high-risk surgery for frail adults
This trial tests whether using high-flow nasal oxygen after surgery helps frail patients recover better and avoid breathing problems. It includes people having long abdominal, vascular, or chest surgeries who have several health risks like older age, low oxygen levels, or heart or lung conditions.
StockholmAges 18 years+ - NCT07465510Recruiting
Ultrasound vs. other methods for double-lumen tube placement
This study compares three ways to check if a breathing tube is in the right spot during lung surgery: using ultrasound, listening with a stethoscope, or looking with a tiny camera. It aims to find which method works best and is safest.
Izmir, İzmirAges 18–65 - NCT07463443Recruiting
Chatbot support for caregivers of elderly pneumonia patients
This study tests a chatbot that gives you information and tips while you care for an elderly loved one with pneumonia. Participating may help you feel more confident and improve your caregiving skills.
Taipei, TaiwanAges 18 years+ - NCT07465757RecruitingPhase 2
Study of alisertib and paclitaxel for small cell lung cancer
This trial tests a combination of two drugs, alisertib and paclitaxel, for people with small cell lung cancer (SCLC) who have already had at least one type of platinum chemotherapy and an immunotherapy. The goal is to see if this treatment can help shrink tumors or slow the cancer's growth.
AlicanteAges 18 years+ - NCT07464587RecruitingPhase 3
Inhaled study drug for moderate to severe copd
This trial tests an inhaled medication (given through a nebulizer) to see how well it improves breathing and quality of life in people with moderate-to-severe COPD. It may help reduce symptoms and flare-ups, but will require regular visits and lung function tests.
Chizhou, AnhuiAges 40–80 - NCT07464912RecruitingPhase 3
Testing TDI01 for idiopathic pulmonary fibrosis
This trial tests a new drug called TDI01 to see if it helps people with idiopathic pulmonary fibrosis (IPF), a lung disease that causes scarring. You may qualify if you have a confirmed IPF diagnosis and your lung function is stable enough.
Beijing, Beijing MunicipalityAges 40–80 - NCT07464314RecruitingPhase 1
Testing a combined flu and COVID-19 mRNA vaccine in older adults
This trial is testing whether a new mRNA vaccine that targets both seasonal flu and COVID-19 is safe and creates a strong immune response. It may offer an easier way to protect against two illnesses with one shot.
Anniston, AlabamaAges 65–85 - NCT07464444Recruiting
Study testing a device that records heart and lung sounds
This study is testing a new device that records heart and lung sounds to see if it can help doctors better understand heart and lung conditions. You may be eligible if you have a known heart condition or if you are generally healthy, and if you've had or will have an echocardiogram (heart ultrasound) in the last or next year.
Montreal, QuebecAges 18–100 - NCT07467863RecruitingPhase 1/Phase 2
Gene-modified immune cells for advanced lung cancer
This trial tests an experimental immune cell therapy (CAR-NK cells) that targets two to three specific markers on your lung cancer cells. It may be an option if your cancer has stopped responding to standard treatments and if tests show your tumor carries those markers.
Shenzhen, GuangdongAges 18–75 - NCT06788470RecruitingPhase 1/Phase 2
Stem cell therapy for severe lung disease in premature babies
This trial tests whether umbilical cord stem cells can help premature babies with severe bronchopulmonary dysplasia (a chronic lung disease) who still need a breathing tube after standard hormone treatment. The goal is to see if it is safe and improves their lung condition.
Hangzhou, ZhejiangAges 8 months+ - NCT06790108Recruiting
AI guidance for learning chest ultrasound
This study tests an AI tool that helps doctors learn to perform endoscopic ultrasound (EUS) better. If you need an EUS to check for problems in your chest, you may be able to join and help improve training for future doctors.
Changsha, HunanAges 18–80 - NCT06785337RecruitingPhase 2/Phase 3
Inhaled nitroglycerin for COPD flare-ups
This trial tests if breathing in a medicine called nitroglycerin can help people with severe COPD and high blood pressure in their lungs. It aims to see if this treatment improves breathing during a COPD exacerbation.
Haram, Giza GovernorateAges 18 years+ - NCT06788366Recruiting
AI tool to predict outcomes in metastatic lung cancer
This trial is testing whether artificial intelligence can help predict how well people with advanced non-small cell lung cancer (NSCLC) respond to immunotherapy or chemo-immunotherapy. If you have stage IV NSCLC and have started this treatment, your data may help build a better prediction tool.
MilanAges 18 years+ - NCT02630121RecruitingPhase 4
Nasal spray treatment to reduce mild sleep apnea congestion
This study tests whether using oxymetazoline with fluticasone nasal spray can improve mild obstructive sleep apnea by lowering nasal congestion. If your nose stays blocked most days despite current spray use, this may help your breathing during sleep.
Tampa, FloridaAges 18–65 - NCT05126589Recruiting
COVID-19 respiratory sample testing using virus genetic clues
This study looks at respiratory samples from adults after COVID-19 to better understand what viruses may be present and how they change over time. If you live in Hong Kong and can consent, you may be able to help researchers learn from your samples and symptoms.
Hong Kong, Hong KongAges 18 years+ - NCT05997602RecruitingPhase 2
Testing FCN-159 for children with LCH that returned
This trial tests a study drug, FCN-159, for children with a rare blood/immune disease called Langerhans cell histiocytosis (LCH) that has not responded to standard treatment or has come back. The goal is to see if this drug can shrink the LCH lesions and help the child feel better.
Beijing, Beijing MunicipalityAges 2–16 - NCT06752720RecruitingPhase 2
Stem cell therapy for chronic stroke patients
This trial tests whether a patient's own stem cells can be safely injected into the brain to help recovery after a stroke. It is for people who had an ischemic stroke 6 months to 5 years ago and still have moderate to severe symptoms.
Sapporo, HokkaidoAges 20–70 - NCT07465848Recruiting
Testing telomere measurement to help diagnose lung cancer
This study uses a simple blood test to measure telomeres (parts of your DNA) to see if it can help detect lung cancer earlier. Researchers will compare results from people with lung cancer, heavy smokers, and low-risk individuals to improve diagnosis.
Elche, AlicanteAges 45 years+ - NCT07464132RecruitingPhase 1/Phase 2
New PET scan for detecting certain diseases
This trial uses a special PET scan tracer to see if it can help find and monitor diseases linked to a protein called FAP. It is for both cancer patients needing a biopsy and healthy volunteers.
Beijing, Beijing MunicipalityAges 18–85
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,347 recruiting pulmonology studies from the U.S. registry right now, out of 9,965 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.