Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,629 recruiting studies in this area right now.
By phase
- Not applicable4,297
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2310
- Phase 4208
- Phase 2/Phase 368
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama174
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas90
- Pennsylvania84
- Colorado71
Recruiting studies6,629 total
- NCT06958666Recruiting
Comparing two breathing exercises for COPD symptoms
This study compares two breathing exercise methods (DITM vs IMT) for people with COPD to see which helps improve symptoms and quality of life better. It's for people who are already using a specific type of inhaler.
Hangzhou, ZhejiangAges 40 years+ - NCT07500376Recruiting
Nutrition and Muscle Health in Lung Cancer Surgery
This study looks at how nutrition and muscle health before lung cancer surgery can affect recovery. It tests whether checking these factors can help predict and improve outcomes after surgery.
Samsun, SamsunAges 18 years+ - NCT06910657RecruitingPhase 1
IDOV-Immune vaccine for advanced solid tumors
This trial tests an experimental virus-based treatment for people with advanced solid tumors that have stopped responding to standard therapies. The treatment is designed to infect and destroy cancer cells while boosting the immune system.
St Louis, MissouriAges 18 years+ - NCT07680764RecruitingPhase 2
Imzokitug plus pumitamig and chemo for first-line advanced lung cancer
This trial tests a new combination of drugs (imzokitug, pumitamig, and platinum-doublet chemotherapy) as a first treatment for advanced or metastatic non-small cell lung cancer that has not spread to the brain. The goal is to see if adding imzokitug makes the standard treatment work better.
Athens, GeorgiaAges 18 years+ - NCT07042243Recruiting
Florida ASCENT cancer study for patients and providers
This study looks at cancer care in Florida. If you have had cancer in the past and are not currently getting active treatment (like chemotherapy or radiation), this study may help researchers understand how to improve care.
Gainesville, FloridaAges 18–100 - NCT07723144Recruiting
Identifying sleep apnea biomarkers
This study compares blood samples from people with moderate-to-severe sleep apnea and those without sleep apnea to find markers that could help diagnose or treat the condition. Half of those with sleep apnea will start CPAP therapy right away, while others wait before starting.
Bialystok, Podlaskie VoivodeshipAges 18–65 - NCT07632365RecruitingPhase 1/Phase 2
Immunotherapy plus chemoradiation for inoperable stage III lung cancer
This trial tests a new combination of immunotherapy and chemotherapy before and after standard chemoradiation for patients with stage III lung cancer that cannot be surgically removed. The goal is to see if this approach improves outcomes compared to chemoradiation alone.
Shanghai, XuhuiAges 18 years+ - NCT06134492RecruitingPhase 3
Acyclovir for pneumonia patients with HSV-1 on breathing support
This trial tests whether acyclovir, an antiviral drug, can help patients with pneumonia who are on breathing support and have herpes simplex virus in their lung fluid. The goal is to see if it improves recovery.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT07723872Recruiting
Finger vs. earlobe oxygen test during a 6-minute walk
This study compares oxygen levels measured at the finger versus the earlobe during a 6-minute walk test for people with interstitial lung disease. It helps find the most accurate way to monitor your oxygen during exercise.
Granollers, SpainAges 18 years+ - NCT07722130Recruiting
Spinal cord stimulation to help breathing after neck injury
This trial tests if a device placed near the spinal cord can help people with a neck injury breathe better without a ventilator. It's for those who still need breathing support at least 2 weeks after their injury.
Nanjing, JiangsuAges 18–75 - NCT07297901Enrolling by invitation
Breathing app study for migraine relief
This trial tests a smartphone-based breathing program to help reduce migraines. It uses heart rate data to guide breathing exercises tailored to you.
Phoenix, ArizonaAges 18 years+ - NCT06848751Recruiting
Tubeless lung surgery for patients with weak lungs
This trial tests whether a tubeless surgery technique (no breathing tube during or after surgery) is safe and effective for people whose lungs are not working well. If you need lung surgery and have trouble breathing, this approach might help you avoid a breathing tube and a stay in the ICU.
Jinan, ShandongAges 14–85 - NCT05882058RecruitingPhase 2
Dose test of a DLL3 cancer drug for neuroendocrine tumors
This Phase 2 study tests how different doses of BI 764532 affect people with small cell lung cancer or certain other neuroendocrine cancers. It may help shrink tumors and improve symptoms after standard treatments have stopped working.
Mobile, AlabamaAges 18 years+ - NCT06437509RecruitingPhase 2
Study of BL-B01D1 plus immunotherapy for extensive-stage small cell lung cancer
This trial tests a new drug combination—BL-B01D1 plus a PD-1 immunotherapy—for people who have just been diagnosed with extensive-stage small cell lung cancer and have not had any prior treatment for it. The goal is to see if this combination can help shrink or control the cancer better than standard therapy.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06576310Recruiting
Predicting teeth changes from sleep apnea mouthpiece treatment
This study looks at people with sleep apnea who are using a special mouthpiece (mandibular advancement device). It aims to find out which factors predict changes in how your teeth fit together after using the device.
ToulouseAges 18 years+ - NCT06991361RecruitingPhase 1
Expanded immune cells and low-dose IL-2 for chronic GVHD
This trial tests whether giving special immune cells (regulatory T cells) grown in a lab, along with a low dose of interleukin-2, can help people with chronic graft-versus-host disease (GVHD) that hasn't improved with steroids. GVHD is a complication after a stem cell transplant where donor cells attack the patient's body.
Boston, MassachusettsAges 2 years+ - NCT06475300RecruitingPhase 2
BL-B01D1 plus immunotherapy for advanced lung and throat cancers
This trial tests a new combination treatment (BL-B01D1 plus a PD-1 inhibitor) for people with advanced lung cancer or nasopharyngeal cancer. It aims to see if the combination is safe and effective for patients whose cancer has not responded to earlier treatments.
Guangzhou, GuangdongAges 18 years+ - NCT06810622Recruiting
NAVIGATE Kidney: Reducing Kidney Health Disparities
This study is testing a program called NAVIGATE Kidney that aims to improve kidney health and reduce racial or ethnic gaps in care. It is for adults with advanced kidney disease (eGFR 15-29) who are not yet on dialysis or had a transplant, and it involves education and support to help manage their condition.
Denver, ColoradoAges 18–75 - NCT05142189RecruitingPhase 1
Testing BNT116 for advanced non-small cell lung cancer
This trial tests an experimental immunotherapy called BNT116, given alone or with other drugs, for people with advanced non-small cell lung cancer (NSCLC). The goal is to see if it is safe and if it can help shrink tumors.
Lexington, KentuckyAges 18 years+ - NCT07720245Recruiting
Self-health app study for adults in Hong Kong
This trial tests a mobile app that helps you check your own health. It is for adults in Hong Kong who want to use the app to learn about their health and get tips.
Hong KongAges 25–65 - NCT07288554RecruitingPhase 1
Study of BBT002 for healthy people and COPD patients
This trial tests an experimental drug called BBT002 in healthy volunteers and people with chronic obstructive pulmonary disease (COPD), a lung condition that makes breathing hard. It aims to see if the drug is safe and how the body processes it.
Hefei, AnhuiAges 18–75 - NCT06429930RecruitingPhase 1
Safety study of L608 in healthy adults
This trial tests an investigational medicine called L608 in healthy volunteers to check its safety and how the body processes it. It may help researchers understand the right dose for future studies.
ChristchurchAges 18–65 - NCT07679893RecruitingPhase 2
Inhaled nintedanib for idiopathic pulmonary fibrosis
This trial tests an inhaled form of nintedanib (a drug that helps slow lung scarring) for people with idiopathic pulmonary fibrosis (IPF). It may be an option for those newly diagnosed or already on stable treatment.
Windsor, OntarioAges 40–80 - NCT06131840RecruitingPhase 1
Study of SGN-CEACAM5C for advanced solid tumors
This trial tests a new drug called SGN-CEACAM5C in people with advanced solid tumors that have not responded to other treatments. The drug targets a protein on cancer cells to try to stop them from growing.
Phoenix, ArizonaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,629 recruiting pulmonology studies from the U.S. registry right now, out of 10,546 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.