Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,347 recruiting studies in this area right now.
By phase
- Not applicable4,045
- Phase 2834
- Phase 1458
- Phase 3422
- Phase 1/Phase 2311
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1988
- Colorectal Cancer88
- NSCLC87
- Chronic Obstructive Pulmonary Disease85
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California383
- Alabama175
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York111
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,347 total
- NCT07407933RecruitingPhase 1/Phase 2
YL201 with other cancer drugs for advanced solid tumors
This trial tests a new drug, YL201, combined with other cancer treatments for people with a certain type of advanced lung cancer (extensive-stage small cell lung cancer). It may help shrink tumors or slow their growth.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07413978RecruitingPhase 1/Phase 2
Stem cell injection for severe ARDS
This trial tests whether an injection of stem cells from umbilical cords can help people with severe ARDS (a type of lung failure) recover faster. It is for those who have not improved after standard treatment and whose ARDS is caused by an infection (not COVID-19).
Wuhan, HubeiAges 18–80 - NCT07413094RecruitingPhase 2
Testing a new drug for sepsis-related lung injury
This trial tests a new medicine called YD0743 for people who have both sepsis (a serious infection) and ARDS (a severe lung injury from the infection). The goal is to see if the medicine helps improve breathing and survival.
BeijingAges 18–75 - NCT07407543RecruitingPhase 1
Study of SRN001 in healthy Korean and Caucasian men
This trial tests a new drug called SRN001 in healthy men to see how safe it is and how the body processes it. It may help find the right dose for future studies.
SeoulAges 19–60 - NCT07412327Recruiting
Proton therapy for early stage lung cancer
This trial tests a precise form of proton radiation for people with early stage lung cancer who cannot have surgery. It aims to see if this treatment is effective and safe.
Guangzhou, GuangdongAges 18 years+ - NCT07408531Recruiting
AI-enhanced lung cancer screening study
This trial uses artificial intelligence to better predict your lung cancer risk from your low-dose CT scan. You will watch a short video, answer a survey, and optionally give a blood sample to help improve future screening.
Chicago, IllinoisAges 50–80 - NCT07412262RecruitingPhase 2
Study of chidamide and ivonescimab for advanced lung cancer after immunotherapy resistance
This trial tests a combination of two drugs (chidamide and ivonescimab) for people with advanced non-small cell lung cancer that stopped responding to initial immunotherapy and has a specific protein marker (YAP) at high levels. It aims to see if this new combination can help when standard immunotherapy no longer works.
Guangzhou, GuangdongAges 18 years+ - NCT07412041Recruiting
Exercise program for stage II-III lung cancer before surgery
This study tests a personalized exercise program for people with stage II or III non-small cell lung cancer who are about to start cancer treatment before surgery. The goal is to see if exercise can help prepare your body for treatment and recovery.
Boston, MassachusettsAges 18 years+ - NCT07410676RecruitingPhase 1/Phase 2
Donor NK cells with IL-15 and pembrolizumab for advanced solid tumors
This trial tests a new type of cell therapy (natural killer cells) made from a donor, combined with low-dose IL-15 (a protein that helps these cells work) and sometimes with pembrolizumab (Keytruda), for people with advanced solid tumors that have not responded to standard treatments. The goal is to see if this combination can shrink tumors or slow their growth.
Beijing, Beijing MunicipalityAges Any age - NCT07413718Recruiting
Breathing muscle training for ALS patients
This study tests whether a special breathing muscle training can help people with ALS maintain lung function. It may benefit patients diagnosed recently with spinal ALS and good breathing capacity.
Donostia / San Sebastian, GipuzkaAges 18–85 - NCT07410494RecruitingPhase 1/Phase 2
Personalized donor cell therapy for advanced solid tumors
This trial tests a personalized cell therapy (CAR-NK) using donor immune cells that are engineered to find and attack one or two markers on advanced solid tumors. It may be an option for people whose tumors have these specific markers and have exhausted other treatments.
Beijing, Beijing MunicipalityAges 8–85 - NCT07414472Recruiting
Can breathing tube leak predict stridor in children?
This study monitors air leaks around a child's breathing tube to see if it can help predict stridor (noisy breathing) after the tube is removed. If you have a child aged 0–16 who has been on a breathing tube for at least 6 hours, they may be eligible.
Antwerp, AntwerpAges Up to 16 years - NCT07413042RecruitingPhase 1
Radiation drug combined with immunotherapy for extensive-stage small cell lung cancer
This trial tests a combination of a radioactive drug ([225Ac]Ac-DOTATATE) and an immunotherapy drug (Tislelizumab) as maintenance treatment for people with extensive-stage small cell lung cancer (ES-SCLC) whose tumors have a specific protein (SSTR). If you have completed first-line treatment and your cancer shows SSTR on a PET scan, this study may be an option.
Beijing, Beijing MunicipalityAges 18–80 - NCT07408375Recruiting
Adjusting breathing machine for tumor ablation
This study tests a new way to adjust the breathing machine (ventilator) during a tumor-destroying procedure called thermal ablation. The goal is to find the safest pressure settings to protect your lungs while you are sedated.
LyonAges 18 years+ - NCT07415005RecruitingPhase 2
Lorlatinib and local therapy for ALK-positive lung cancer
This study combines a daily targeted pill (lorlatinib) with a short course of radiation or surgery to treat ALK-positive lung cancer. The goal is to see if this two-step approach delays the cancer from growing.
Houston, TexasAges 18 years+ - NCT07409727RecruitingPhase 4
Acetylcysteine inhalation to prevent pneumonia in ventilated patients
This trial tests if breathing in a medication called acetylcysteine can help prevent lung infections in patients who are on a breathing machine. If you or a loved one is on a ventilator, this treatment might reduce the chance of getting ventilator-associated pneumonia.
CairoAges 18–64 - NCT07412769Recruiting
Asthma attack management study for ages 6 to 17
This study looks at how asthma attacks are managed in children and teens ages 6 to 17 who come to the emergency department. It aims to improve treatment for acute asthma flare-ups.
Ferrara, FEAges 6–17 - NCT07414108Recruiting
Predicting response to breathing support in COPD
This study looks at whether nighttime breathing problems can predict long-term success with a non-invasive breathing machine in people with COPD who have high carbon dioxide levels in their blood. The goal is to help doctors decide who will benefit most from this therapy.
BolognaAges 18 years+ - NCT07411417Recruiting
Acupressure for pain and lung function after chest surgery
This trial tests if acupressure can help reduce pain and improve lung function after a first-time chest surgery. It may offer a non-drug way to support recovery.
IstanbulAges Any age - NCT07410975RecruitingPhase 2
Immunotherapy and chemo before surgery for lung cancer
This trial tests combining two immunotherapy drugs (anti-CTLA-4 antibody and sintilimab) with chemotherapy before surgery for stage II-III non-small cell lung cancer. The goal is to see if this approach helps shrink tumors and improve outcomes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07408635RecruitingPhase 2
New Immunotherapy Plus Chemotherapy Before Lung Cancer Surgery
This trial tests a new combination of an immunotherapy drug (IBI363) plus chemotherapy before surgery in people with Stage III lung cancer that can't be removed at first. The goal is to shrink the tumor so it can be surgically removed.
ShanghaiAges 18 years+ - NCT06821776Recruiting
Comparing feeding methods for infants with severe lung disease
This study compares two ways of feeding infants with severe bronchopulmonary dysplasia (a chronic lung condition in premature babies) to see which helps with feeding problems such as reflux or aspiration. Infants will try both methods at different times to find out which works best.
Memphis, TennesseeAges 1 month–1 year - NCT06822504Recruiting
Sarcopenic obesity in COPD: a prevalence study
This study looks at how common it is to have both COPD (a chronic lung disease) and sarcopenic obesity (loss of muscle with excess body fat). By joining, you'll help doctors understand this condition better and may get a full health check-up.
Roma, RomaAges 40–100 - NCT06821451Recruiting
Robot-guided dye marking for lung nodule surgery
This trial tests a new way to find and remove small lung nodules using a robot-guided camera to mark the nodule with dye, then a video-assisted surgery to remove it. It may help patients whose nodules are hard to locate during surgery.
Shanghai, Shanghai MunicipalityAges 18–80
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,347 recruiting pulmonology studies from the U.S. registry right now, out of 9,965 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.