Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,347 recruiting studies in this area right now.
By phase
- Not applicable4,045
- Phase 2834
- Phase 1458
- Phase 3422
- Phase 1/Phase 2311
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1988
- Colorectal Cancer88
- NSCLC87
- Chronic Obstructive Pulmonary Disease85
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California383
- Alabama175
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York111
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,347 total
- NCT07393490Recruiting
Extra oxygen during lung cancer surgery
This study tests whether giving extra oxygen during surgery helps people who are having part of their lung removed for lung cancer. It may help keep oxygen levels stable while the lung is not being used for breathing.
OsijekAges 18 years+ - NCT07395596RecruitingPhase 4
Remimazolam for Bronchoscopy in High-Risk Patients
This trial tests a sedative called remimazolam for people who are at higher risk during a painless bronchoscopy (a lung exam). It aims to see if this drug is safe and effective for you.
Hangzhou, ZhejiangAges 18 years+ - NCT07394816Recruiting
Can ultrasound-guided pain blocks reduce lung complications after abdominal surgery?
This study tests whether using ultrasound-guided pain blocks (fascial plane blocks) during major abdominal surgery can reduce lung complications after surgery, especially in older adults. It may offer better pain control and faster recovery.
Yenimahalle, AnkaraAges 65 years+ - NCT07394062Recruiting
Comparing chemo-immunotherapy combinations for advanced lung cancer
This study compares two standard treatments for metastatic non-small cell lung cancer when the tumor has low levels of a protein called PD-L1. It looks at how well chemotherapy plus pembrolizumab works versus chemotherapy plus nivolumab and ipilimumab.
AnkaraAges 18 years+ - NCT07391280Recruiting
Finding cancer, COPD, and heart failure early in the ER
This trial tests a computer program that looks at chest X-rays to help doctors spot early signs of cancer, COPD (a lung disease), and heart failure. It aims to catch these conditions sooner so patients can get the right care faster.
GlasgowAges 18 years+ - NCT07395297Recruiting
Airway clearance therapy for ICU lung infections
This trial tests a new airway clearance device in ICU patients with pneumonia. It may help clear mucus from your lungs and improve breathing without needing a breathing tube.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07397455RecruitingPhase 1
COVID-19 Omicron Human Challenge Study
This study is a 'human challenge' trial where healthy volunteers who have been vaccinated and have low antibody levels are deliberately exposed to a newer Omicron variant of COVID-19. The goal is to learn how the virus spreads and how to test treatments or vaccines.
LondonAges 18–50 - NCT06568159Recruiting
Sleep apnea treatment in heart patients
This study looks at how well people with heart disease or high heart risk follow their sleep apnea treatment, comparing a mouth device (MAD) to a CPAP machine. It aims to find which treatment works better for daily use.
MontpellierAges 18 years+ - NCT05818319Recruiting
Tracking kidney urine effects after a short pause in CF therapy
This study checks how a common cystic fibrosis (CF) medicine affects urine markers after briefly stopping it and then restarting. The goal is to better understand whether the treatment shift changes kidney-related signals in people with CF.
Aarhus C, Central JutlandAges 18 years+ - NCT04256798RecruitingPhase 3
Respiratory care after high-risk abdominal surgery
This trial looks at a breathing-focused care plan given around the time of major abdominal surgery to improve recovery and outcomes. You may be eligible if you’re having a large midline abdominal incision and can be followed after surgery.
Botucatu, São PauloAges 10–100 - NCT04790240RecruitingPhase 1/Phase 2
Herbal treatment aimed to reduce COVID-19 inflammation
This early-stage trial studies whether certain medical herbs can lower inflammation in people with recent COVID-19 and help the immune system better fight the virus. You may be able to join whether or not you take standard COVID medicines, but you would need to complete the herb plan and provide specific lab and scan results.
Rockville, MarylandAges Any age - NCT05822193Recruiting
Study of long COVID in Brazil
This study looks at how often “post-COVID-19 condition” (long COVID) happens, what factors are linked to it, and how much it affects people’s daily lives. It may help researchers better understand long COVID and who is most impacted.
Cachoeirinha, Rio Grande do SulAges 18 years+ - NCT05703191Recruiting
Tests an inhaled nitric oxide system for newborn lung pressure
This study looks at whether an inhaled nitric oxide generator and delivery system can help newborns with high lung blood pressure (pulmonary hypertension). It may help improve oxygen levels during breathing support, but it requires specific medical eligibility and informed consent.
Guangzhou, GuangzhouAges Any age - NCT06528444RecruitingPhase 3
Dexamethasone vs placebo for severe flu patients
This trial tests whether dexamethasone (a steroid) can help people hospitalized with severe flu recover faster. It is for adults who are already taking Tamiflu and do not have other serious infections like COVID-19.
AlicanteAges 18–100 - NCT07381790Recruiting
Modern tools for lung infections in children
This study tests modern technology for diagnosing and treating lower respiratory infections in children. It may help kids with symptoms like fast breathing, wheezing, or chest retractions.
Ålesund, Møre og RomsdalAges birth–2 years - NCT06827184Recruiting
Best time for lying on stomach with severe lung failure
This trial is for people with severe lung failure (ARDS) who need a breathing machine. It tests how long lying on your stomach (prone position) helps improve breathing, by measuring changes in your body's oxygen levels and other vital signs.
TaipeiAges 18 years+ - NCT07382258Recruiting
Inhaled nitric oxide for COPD: a clinical study
This trial tests whether a gas called nitric oxide, breathed in through the nose or mouth, can help people with moderate to severe COPD. It could improve breathing and quality of life.
Nanjing, JiangsuAges 40–75 - NCT07380711Recruiting
How dupilumab works for COPD in real life
This study looks at how well dupilumab works for people with uncontrolled COPD who have high levels of a certain white blood cell (eosinophils). It collects information from routine doctor visits to see how patients feel and if the treatment is safe.
Aix-en-ProvenceAges 18 years+ - NCT07387094RecruitingPhase 3
A study of XW003 for obesity with sleep apnea (no CPAP)
This trial tests an investigational weekly injection called XW003 for weight loss in people who have obesity and moderate-to-severe sleep apnea but do not use a CPAP machine. It aims to see if the drug can help with weight loss and improve sleep apnea without the need for a breathing machine.
Beijing, Beijing MunicipalityAges 18–75 - NCT07381829RecruitingPhase 1
HC010 plus chemotherapy for advanced lung cancer
This trial tests an experimental drug called HC010 combined with chemotherapy for people with advanced lung cancer, including certain types of non-small cell or small cell lung cancer. It aims to see if the combination is safe and effective.
Guangzhou, GuangdongAges 18–75 - NCT07388680RecruitingPhase 2/Phase 3
Pirfenidone for radiation lung injury with or without immune pneumonia
This trial tests if pirfenidone capsules can help treat lung damage caused by radiation therapy, with or without immune-related pneumonia. It may be suitable for people with mild to moderate lung function impairment who have recently developed radiation lung injury.
Hefei, AnhuiAges 18–75 - NCT06833632Recruiting
Studying cancer cells in the blood and air spaces for early lung cancer
This study looks for cancer cells that travel through the blood or spread through air spaces in the lungs of people with early-stage lung cancer. The goal is to understand how these cells affect the disease, and it may help doctors plan better treatment in the future.
Bologna, Emilia-RomagnaAges 18 years+ - NCT03656081RecruitingPhase 3
Treating chronic lung Aspergillus with inhaled and oral antifungals
This study tests whether a combination of inhaled liposomal amphotericin B (Ambisome) plus itraconazole works better for chronic pulmonary aspergillosis (CPA). It may help control long-term Aspergillus lung infection and symptoms.
PoitiersAges 18 years+ - NCT04866472Recruiting
GlideRite vs other tube tool for hard airway intubation
This study compares two medical tools used to place a breathing tube through the mouth when intubation is expected to be difficult. It aims to find which tool is safer and works better for people with higher risk of a “hard airway.”
Louisville, KentuckyAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,347 recruiting pulmonology studies from the U.S. registry right now, out of 9,965 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.