Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,630 recruiting studies in this area right now.
By phase
- Not applicable4,296
- Phase 2851
- Phase 1471
- Phase 3426
- Phase 1/Phase 2310
- Phase 4208
- Phase 2/Phase 368
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer85
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Ovarian Cancer73
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)41
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California394
- Alabama174
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Colorado71
Recruiting studies6,630 total
- NCT04078243Recruiting
Trial setup and testing in adults with pulmonary hypertension
This study tests new “trial tools” and designs for running early research in people with pulmonary hypertension. If you qualify, you may be asked to do extra trial-related procedures to help researchers test the process safely and smoothly.
Sheffield, South YorkshireAges 18 years+ - NCT04079179RecruitingPhase 2
Cobimetinib for difficult Langerhans cell and similar disorders
This Phase 2 trial studies cobimetinib, a medicine that targets a specific growth-and-signal pathway, to treat stubborn (refractory or worsening) Langerhans cell histiocytosis and related disorders. It may help shrink active disease or stop disease from progressing.
Phoenix, ArizonaAges Any age - NCT04083417RecruitingPhase 4
Sore throat study comparing antibiotics versus no antibiotics
This trial looks at whether phenoxymethylpenicillin (an antibiotic) helps people with a certain type of sore throat more than not using antibiotics. You may qualify if your symptoms match a likely bacterial cause and a rapid test for strep is negative.
JönköpingAges 15 years+ - NCT04086082Recruiting
Marker-free X-ray guidance during lung radiotherapy
This study tests a way to guide lung radiation using X-ray images during treatment, without using implanted tracking markers for every step. It may help doctors target tumors more accurately while you receive external beam radiotherapy.
Melbourne, VictoriaAges 18 years+ - NCT04092660Recruiting
Mouth guard study to reduce airway collapse in sleep apnea
This study tests whether using an anti-snoring mouth guard (a mandibular advancement appliance) can help keep your airway open during sleep if you have obstructive sleep apnea. If you’re referred for this kind of mouth guard, the trial will see if using it more regularly or in a specific way improves symptoms or breathing during sleep.
LondonAges 40–90 - NCT04095351Recruiting
Study of connective tissue disease affecting the lungs
This study looks at people aged 18 and older who have a connective tissue disease and lung involvement. It aims to better understand how these lung problems progress and may help doctors choose better care.
InnsbruckAges 18–80 - NCT04095676Recruiting
Surgery vs drainage for infected fluid around the lung
This trial compares two ways to treat pleural empyema, which is infected fluid and pus around the lung. It looks at whether a minimally invasive surgery (VATS) works better than drainage in helping people recover.
Aarhus, AarhusAges 18 years+ - NCT04098445Recruiting
Study of lung injury in children after stem cell transplant
This study follows children and teens who get a stem cell transplant to learn how lung problems develop over time. Your participation could help doctors better predict, prevent, and manage lung injury after transplant.
San Francisco, CaliforniaAges Up to 24 years - NCT04105270RecruitingPhase 2
Durvalumab plus chemo with RMT for lung cancer
This Phase 2 trial studies a new treatment plan that combines RMT with durvalumab and chemotherapy in people with untreated advanced lung adenocarcinoma. It aims to improve outcomes by helping the immune system and fighting cancer cells together.
Phoenix, ArizonaAges 18 years+ - NCT04115254Recruiting
MRI-guided focused radiation for certain tumors
This study tests a type of high-precision radiation guided by MRI pictures to treat certain cancers. It may help doctors deliver radiation more accurately while avoiding nearby healthy tissue, but you must be able to safely complete an MRI scan and meet tumor-size and health requirements.
Boston, MassachusettsAges 18 years+ - NCT04118660Recruiting
Thoracic specimen registry for adults with chest conditions
This study is a “specimen registry,” meaning it collects and stores samples from adults with chest (thoracic) diseases. It may help researchers better understand lung and chest conditions and improve future testing or treatments.
Rochester, MinnesotaAges 18 years+ - NCT04124848Recruiting
Sleep apnea study for Somali community adults
This study looks at obstructive sleep apnea—breathing pauses or poor breathing during sleep—in Somali community members. It aims to learn more about sleep apnea in this specific group, which can help guide better care.
Rochester, MinnesotaAges 18 years+ - NCT04136535RecruitingPhase 2
Treating resistant lung cancer with chemo plus or minus an added drug
This Phase 2 study tests whether adding an extra targeted medicine (anlotinib) to standard chemotherapy (pemetrexed and carboplatin) can better control osimertinib-resistant lung cancer with an EGFR mutation. It’s for people whose lung cancer has already progressed after osimertinib, and it aims to shrink tumors and slow the disease.
Shenzhen, shenzhenAges 18–75 - NCT04137133Recruiting
Precision medicine study for young children with cystic fibrosis
This study enrolls newly diagnosed infants with cystic fibrosis to follow them during “precision medicine” care. It may help doctors better understand which treatments and monitoring work best, especially before certain infections develop.
RoscoffAges Up to 18 years - NCT04145024Recruiting
Pulmonary hypertension registry and blood sample biobank
This study keeps a health registry and biobank for people diagnosed with pulmonary hypertension using a specific heart test. It helps researchers better understand the condition and may improve future care.
GiessenAges Any age - NCT04147078RecruitingPhase 1
Personalized immune vaccine after surgery for certain cancers
This Phase 1 study tests a personalized vaccine made for you to help your immune system after you’ve had surgery or ablation for certain cancers. It’s mainly done to check safety and see how well the vaccine can work at preventing cancer from coming back.
Chengdu, SichuanAges 18–100 - NCT04147286RecruitingPhase 2/Phase 3
Atorvastatin to lower lingering inflammation after TB treatment
This trial studies whether atorvastatin (a cholesterol medicine) can reduce ongoing inflammation after you finish standard tuberculosis (TB) treatment. If it works, it may improve how your body recovers after TB, especially by lowering inflammation-related signals.
Observatory, WCAges 18–65 - NCT04151940Recruiting
PET/CT scan changes during chemo with immune therapy
This study looks at how PET/CT scan results change while you receive chemo plus an immune therapy (a PD-1/PD-L1 medicine) for stage IV lung cancer. The goal is to better understand what the scans mean during treatment, which may help guide care in the future.
Seattle, WashingtonAges 18 years+ - NCT04157361Recruiting
Non-invasive lung testing in asthma and cystic fibrosis
This trial studies how well a non-invasive lung test can show lung involvement in people with asthma (especially IgE-related asthma) and people with cystic fibrosis. You might benefit by getting extra lung assessments without invasive procedures.
OlomoucAges Any age - NCT04157049Recruiting
Alpha-1 research registry for diagnosed people and carriers
This registry study enrolls people with Alpha-1 Antitrypsin Deficiency or certain genetic “carriers” to help researchers learn more about the condition. If you join, you may be asked to share health information over time.
Coral Gables, FloridaAges Any age - NCT04158479Recruiting
Registry for people on ECMO life support
This registry collects information about people who are placed on ECMO, a heart-lung machine used to support breathing and/or circulation. It may help doctors better understand who benefits and how to manage ECMO in the future.
Beijing, Beijing MunicipalityAges Any age - NCT04160715Recruiting
Registry for people with idiopathic pulmonary fibrosis in Korea
This study is a registry that collects health information from people diagnosed with idiopathic pulmonary fibrosis (IPF). It may help researchers better understand IPF and how it changes over time, even if it doesn’t involve a new medication.
Seongnam-siAges 30–100 - NCT04164173Recruiting
Breathing therapies after heart surgery for lung overinflation
This study looks at breathing (respiratory) therapies to help after certain heart surgeries that can cause the lungs to feel overly inflated. If you’re eligible, you may receive and be assessed for how well these breathing treatments work during your recovery.
Dallas, TexasAges 18–80 - NCT04165070RecruitingPhase 1/Phase 2
Stage IV lung cancer trial using pembrolizumab with or without chemotherapy
This Phase 1/2 study tests pembrolizumab (an immune-based cancer treatment) either alone or with chemotherapy in people newly diagnosed with stage IV non-small cell lung cancer (NSCLC). It looks at how well the treatments work and whether they are safe, especially in people who haven’t had treatment yet for metastatic disease.
Gilbert, ArizonaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,630 recruiting pulmonology studies from the U.S. registry right now, out of 10,558 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.