Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,770 recruiting studies in this area right now.
By phase
- Not applicable6,416
- Phase 2492
- Phase 1248
- Phase 3239
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety388
- Depression381
- Alzheimer Disease338
- Autism Spectrum Disorder240
- Dementia226
- Mild Cognitive Impairment195
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder144
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health98
- Autism94
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University61
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California517
- Massachusetts266
- New York256
- Texas209
- Maryland175
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,770 total
- NCT06882538Recruiting
Mindfulness program for schizophrenia patients
This study tests if a one-on-one mindfulness-based psychoeducation program can help reduce internalized stigma and promote healthy lifestyle behaviors in people with schizophrenia. It aims to provide a supportive approach to improve well-being.
Kastamonu, CentralAges 18 years+ - NCT03705715RecruitingPhase 1
Study brain immune-cell activity in different mental and brain conditions
This Phase 1 study looks for patterns (correlates) in how “microglial” brain immune cells become activated across different neuropsychiatric conditions and in healthy volunteers. It uses brain imaging to help researchers understand what might drive symptoms and differences between people.
Houston, TexasAges 18–80 - NCT04700878Recruiting
Compassion course study for healthcare workers under stress
This trial tests whether a digital “compassion” training course can reduce stress in people who work directly with patients. You may be offered the course (or not, depending on random assignment) to see if it improves how you feel at work.
Vaxjo, Kronoberg CountyAges 20 years+ - NCT05980117RecruitingPhase 4
Remimazolam sedation for cataract surgery
This study tests a sedative, remimazolam, for older adults having their first cataract surgery. It aims to see if it helps keep patients comfortable and calm without needing general anesthesia.
Los Angeles, CaliforniaAges 65 years+ - NCT07286955Recruiting
Soldier health study for active duty at Fort Hood
This study is for active-duty soldiers at Fort Hood (now Fort Cavazos) who want to take part in a program aimed at improving their well-being and readiness. The goal is to see if the program helps soldiers feel better and perform better.
Fort Hood, TexasAges 18 years+ - NCT07286383Recruiting
Can peer support specialists help prevent veteran suicide?
This trial tests whether working with a VA peer specialist—another veteran trained to offer support—can reduce suicide risk for veterans who are having thoughts of suicide. You'll get extra support for up to 6 months.
Baltimore, MarylandAges 18 years+ - NCT06619613RecruitingPhase 1
Study of CM383 for early Alzheimer's disease
This trial tests a new drug called CM383 in people with mild cognitive impairment or mild Alzheimer's disease. The goal is to see if it can help slow down memory loss.
HefeiAges 50–85 - NCT06660602Recruiting
Brain function check before and after heart surgery
This study checks how well your brain works before and after heart surgery. It uses safe tests like a CT scan and an EEG to see if surgery affects brain function.
BeijingAges 18–80 - NCT06688968Recruiting
Music, thinking, and memory in Parkinson's and Alzheimer's
This study looks at how music engagement affects thinking and memory in people with Parkinson's or Alzheimer's disease. It may help researchers understand how music can support brain health as we age.
Montpellier, HéraultAges 60 years+ - NCT07286175RecruitingPhase 2
Study of brenipatide for bipolar disorder
This trial tests an experimental drug called brenipatide for people with bipolar I or II disorder. It aims to see if the drug can help manage mood episodes when added to your current stable medications.
Orange, CaliforniaAges 18–75 - NCT07281261Recruiting
Nerve stimulation for alcohol use disorder
This study tests whether a mild nerve stimulation device (tAN) can help reduce alcohol cravings and withdrawal. It's for people with moderate to severe alcohol use disorder who are going through withdrawal and do not use tobacco.
Houston, TexasAges 18–64 - NCT07282678Recruiting
Adaptive brain stimulation for treatment-resistant depression.
This study tests a new brain stimulation device that adjusts its signal in real time to treat depression. It's for people who haven't gotten enough help from antidepressants and are looking for a non-drug option.
Durham, North CarolinaAges 22 years+ - NCT07284472RecruitingPhase 2/Phase 3
Testing drugs for agitation in Alzheimer's disease
This trial tests two new drugs (EXV-802 and EXV-801) to see if they can safely reduce moderate to severe agitation in people with Alzheimer's dementia. If you or a loved one has Alzheimer's and has been experiencing significant agitation for at least two weeks, this study may be an option.
Murrieta, CaliforniaAges 55–90 - NCT07284667RecruitingPhase 2
A new medicine for depression that hasn't improved with other treatments
This trial tests a new medicine called ACP-211 in adults with major depression who have not gotten enough relief from at least two previous antidepressants. The goal is to see if it can help when other treatments have not worked well.
Birmingham, AlabamaAges 18–65 - NCT07280065RecruitingPhase 3
Testing a smartphone tool for PTSD diagnosis
This study tests a new tool (Senseye) that uses an iPhone camera to help diagnose PTSD. You will have a few video visits and answer questions about your mood and experiences.
Aurora, ColoradoAges 18 years+ - NCT06884046Recruiting
Supporting parents of babies with heart conditions
This study offers support to parents whose baby is diagnosed with a heart condition before birth and will need surgery shortly after birth. The goal is to help parents manage stress during this difficult time.
Pessac, FranceAges birth–4 weeks - NCT06853743RecruitingPhase 2
Study of nicotinamide riboside for Huntington's disease
This trial tests if a vitamin B3-like supplement, nicotinamide riboside, can help people with early to mid-stage Huntington's disease. You will be randomly assigned to take the supplement or a placebo to see if it slows the disease.
OsloAges 18–80 - NCT06859892RecruitingPhase 4
Drug combo study for better sleep after major surgery
This study tests whether a combination of two medicines, dexmedetomidine and esketamine, can help improve sleep problems after major non-heart surgery. You may be eligible if you are having planned surgery lasting at least one hour and will use a pain pump after surgery.
BeijingAges 18 years+ - NCT06883708Recruiting
Online program for dementia caregivers in Malaysia
This trial tests an online program called iSupport-Malaysia to help people who care for a family member with dementia. It aims to reduce stress, burden, and symptoms of depression or anxiety.
Petaling Jaya, Kuala LumpurAges 18–100 - NCT06883019Recruiting
Lecanemab for early onset inherited Alzheimer's
This trial tests a medication called lecanemab for people with early onset familial Alzheimer's disease. It aims to see if the drug can help slow cognitive decline in those with confirmed signs of Alzheimer's in their brain.
Beijing, ChinaAges 18–65 - NCT07287410Recruiting
Assessing thinking and daily life in dementia and MCI
This study looks at how dementia or mild cognitive impairment affects thinking, daily living, and mood. The goal is to better understand these conditions by doing careful assessments.
Messina, MEAges 50–86 - NCT07280481Recruiting
Mindfulness for emotional distress
This trial tests a weekly mindfulness program to help people with anxiety or depression. It aims to see if learning mindfulness can improve your emotional health.
BeijingAges 18 years+ - NCT07282704Recruiting
Falls study for people with intellectual disabilities
This study looks at what makes people with intellectual disabilities more likely to fall. It aims to create a way to predict falls, which can help prevent them and keep you safer.
Betanzos, A CoruñaAges 18 years+ - NCT07281092Recruiting
Comparing ADHD therapy options for teens
This study compares two types of therapy—organizational skills training and mindfulness—to see which helps teens with ADHD more. You'll attend group sessions and learn skills to help with focus, planning, and managing daily life.
Seattle, WashingtonAges 13–17
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,770 recruiting psychiatry studies from the U.S. registry right now, out of 12,391 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.