Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT05837039Recruiting
Comparing caregiver and nurse views of discomfort in advanced cancer
This study compares how healthcare providers and family caregivers judge discomfort in people with advanced cancer who are very hard to rouse and may be actively dying. It aims to understand whether caregiver and staff perceptions match, which could improve comfort care for patients near the end of life.
Houston, TexasAges 18 years+ - NCT05818384Recruiting
Health program for Choctaw youth to improve daily habits
This is a community health program for Choctaw Nation of Oklahoma youth that tries to improve habits related to food, movement, and screen time. It may help you build healthier routines for everyday life.
Durant, OklahomaAges 12–19 - NCT05812339Enrolling by invitation
Mapping tests for stomach symptoms using body-surface sensors
This study checks whether a noninvasive “mapping” test placed on the belly and chest can help tell apart people with certain upper stomach symptoms from healthy controls. It may help researchers better understand stomach function and symptoms without relying only on invasive tests.
Calgary, AlbertaAges 18 years+ - NCT05824234Recruiting
REFOCUS program for mental health care teams
This trial tests whether a training program for mental health teams improves care for people with certain mental health conditions. You may be included if your clinic/team is using the REFOCUS training and you meet the study language and consent requirements.
Lyon, RhôneAges 15–65 - NCT05838274Recruiting
Study of alcohol effects and brain scans in bipolar disorder
This study gives a controlled amount of alcohol and uses brain MRI scans to understand how alcohol affects people with bipolar disorder. It may help researchers find brain and behavior patterns that explain differences in alcohol responses.
Austin, TexasAges 21–26 - NCT05832268Enrolling by invitation
Pelvic floor recovery after childbirth anal sphincter injury
This study looks at how the pelvic floor (the support muscles and tissues) works in people who had a specific anal sphincter injury during vaginal birth, compared with people who had uncomplicated vaginal deliveries. It may help doctors better understand recovery and function after childbirth injuries.
OsloAges 18 years+ - NCT05829161Recruiting
Studying autism and typical brain/sensory patterns in people 12–40
This study looks at differences in “sensory” (how you experience sounds, touch, and other sensations) between people with autism and people without autism. The results may help researchers understand autism better and improve support in the future.
TaipeiAges 1.5 years+ - NCT05837091RecruitingPhase 4
Low-dose sodium oxybate for idiopathic hypersomnia sleepiness
This trial tests whether low-dose sodium oxybate can improve symptoms in adults with idiopathic hypersomnia, a condition that causes excessive sleepiness. You’d likely be asked to pause this standard treatment briefly while baseline testing is completed, and you’d use reliable contraception during and after the study drug.
Phoenix, ArizonaAges 18–65 - NCT05830942Recruiting
Training walks plus brain stimulation for thinking skills in older adults
This study tests whether a structured walking exercise, combined with brain stimulation and brain scans, can improve or slow decline in thinking skills. It’s aimed at older adults who notice memory or confusion getting worse.
Gainesville, FloridaAges 65 years+ - NCT05843695Recruiting
Therapy study for PTSD and anxiety in veterans
This trial tests a psychotherapy approach to help veterans and service members who have PTSD and/or anxiety disorders. You may be randomly assigned to different therapy conditions, and the study aims to improve quality of life and reduce anxiety and PTSD symptoms.
Houston, TexasAges 18 years+ - NCT05815199Recruiting
E-cigarettes to help smokers with serious mental illness cut down
This study tests whether e-cigarettes can help people who smoke a lot reduce cigarette use (without requiring them to quit completely). It is designed for adults with serious mental illness and focuses on harm reduction and follow-up over time.
New York, New YorkAges 21 years+ - NCT05825820Recruiting
Phone-based outreach to help prevent future suicide attempts
This pilot study tests a health care and community outreach program that contacts people after an Emergency Department (ED) visit to help prevent suicide attempts. You may get follow-up support through partners like Samaritans of Boston using phone, text, or email.
Boston, MassachusettsAges 18 years+ - NCT05842330RecruitingPhase 3
Testing ADHD treatment benefits for people in custody
This Phase 3 study tests whether treating attention-deficit/hyperactivity disorder (ADHD) helps people who are incarcerated. You might be eligible if you meet ADHD diagnosis requirements, can consent, and are able to take ADHD medicine safely.
Geneva, Canton of GenevaAges 18–65 - NCT05841212Enrolling by invitation
DBT skills group for teens with ADHD
This trial offers a skills group (DBT) to help teens with ADHD manage challenging emotions and behaviors. It’s meant for ages 13–16 who can participate safely in a group setting.
LondonAges 13–16 - NCT05843604Recruiting
Brain and thinking tests to study OCD treatment resistance
This study looks at brain and thinking (cognitive) markers to understand why some people with obsessive-compulsive disorder (OCD) don’t respond as well to treatment. If you have OCD, you may be asked to take tests and follow the study rules to help researchers better predict treatment resistance.
PoitiersAges 18–70 - NCT05837104RecruitingPhase 2
Magnesium and vitamin B6 for early bipolar depression
This Phase 2 trial tests whether magnesium plus vitamin B6 can reduce depressive symptoms in people who are newly diagnosed with bipolar I disorder. It also checks for safety over a short, 4-week treatment period.
Belmont, MassachusettsAges 18–50 - NCT05814822Recruiting
CBT for sleep problems in adults using cannabis
This study looks at a sleep-focused treatment to help adults who have ongoing insomnia and also use cannabis regularly. If sleep improves, the trial hopes it may also improve overall outcomes for cannabis use.
Ann Arbor, MichiganAges 21 years+ - NCT05826457Enrolling by invitation
Study for early RBD as a possible Parkinson’s risk
This study looks at people with REM sleep behavior disorder (RBD), confirmed by a sleep test, who may be in the early “prodromal” stage before Parkinson’s or related diseases. It also enrolls healthy controls to compare results from brain and body testing to better understand who is at risk.
Los Angeles, CaliforniaAges 18 years+ - NCT05832489RecruitingPhase 3
EEG-MRI test of methylphenidate in adult attention symptoms
This Phase 3 study tests how methylphenidate affects brain signals and attention in adults with ADHD, and in adults with mood-related attention problems. It also includes healthy volunteers to compare brain responses during brain scanning.
StrasbourgAges 18–60 - NCT05826860Recruiting
Mindfulness and storytelling for graduate student well-being
This study tests whether a mindfulness and storytelling program can improve well-being for graduate students. It is meant for people who are new to mindfulness and want support during graduate school.
Madison, WisconsinAges 18 years+ - NCT05822362RecruitingPhase 2
CBD for People with Early Memory Trouble Risk
This Phase 2 study tests whether CBD (a cannabis-derived product) can improve thinking and memory in people who are at risk for Alzheimer’s disease. You would be followed for about 24 weeks with memory/thinking check-ins and require a study partner to help with certain assessments.
Aurora, ColoradoAges 55–85 - NCT05846282Recruiting
Student program to reduce mental health strain of resilience
This study is looking at ways to reduce the mental health and health burdens some students carry while trying to be “resilient.” It is for certain high school students in specific grades and backgrounds, to see if the program can help them feel better.
Los Angeles, CaliforniaAges 13 years+ - NCT05825040Recruiting
Testing an online mental health program for anxiety and depression
This trial tests an “online” mental health approach to help people with moderate to severe anxiety and/or depression. If you qualify, you may be invited to use the program and share feedback as part of a study.
Shatin, N.T.Ages 17 years+ - NCT05830422Enrolling by invitation
Predicting late thinking problems after cardiac arrest
This study looks at how to predict delayed cognitive (thinking) impairment in people who survived a cardiac arrest but initially seemed neurologically okay. It may help identify who is at higher risk so follow-up and support can be planned earlier.
Daejeon, Seo-guAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.