Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT05584449Recruiting
After-cancer group program for young adult survivorship goals
This trial offers a structured group curriculum to help young adults after cancer treatment manage survivorship concerns and improve outcomes. You may be eligible if you finished curative cancer treatment recently and can fully join all six group meetings.
Scottsdale, ArizonaAges 18–39 - NCT05551728Recruiting
Autism coaching for caregivers of young children
This study tests a caregiver coaching program to help parents or guardians support a young child with autism. It aims to improve day-to-day skills using structured sessions delivered over time.
Cape Town, West CapeAges 1.5 years–6 years - NCT05567640Recruiting
Smart digital mental health support
This study tests a digital mental health program that uses smart technology to personalize your experience and keep you engaged. If you join, you may get a more tailored approach to improving your mental well-being.
Boston, MassachusettsAges 18 years+ - NCT05582161RecruitingPhase 2
Test drug target for Alzheimer’s or memory loss
This Phase 2 study looks at how well a medicine that targets DAO (an enzyme in the body) helps people with Alzheimer’s disease or mild cognitive impairment. You may be considered if your memory symptoms are mild to moderate and you meet specific brain-function and symptom scoring rules.
Kaohsiung CityAges 50–90 - NCT05562258Recruiting
Peer coaching for teens with eating disorders
This study tests a “peer-coaching” program where a teen receives support from someone with lived experience, alongside their care. It may help improve how teens manage their eating disorder treatment and feel supported during recovery.
New York, New YorkAges 12–18 - NCT05574634Recruiting
Study of brain signaling and distraction in aging adults
This study looks at how a deep brain area helps people focus and ignore distractions as we get older. You may be invited if you’re a healthy adult and can safely complete brain-related testing.
Blacksburg, VirginiaAges 18–75 - NCT05556395Recruiting
Study after stroke to help thinking and memory recovery
This trial looks at stroke patients who can show specific scan findings on an MRI, then uses thinking tests by phone to track cognitive (thinking and memory) changes. It may help researchers understand whether targeting brain blood-flow disruption can improve post-stroke cognition.
Baltimore, MarylandAges 18 years+ - NCT05591937Recruiting
Online therapy and prevention support for eligible East LA students
This project offers online mental health prevention and therapy programs and short assessments for eligible students. It may help you access support in a convenient way if you meet the study’s student, coverage, and technology needs.
Los Angeles, CaliforniaAges 18–40 - NCT05570344Recruiting
Texting support plus brain stimulation for hard-to-treat depression
This study tests whether adding supportive text messages to brain stimulation (repetitive TMS) helps people with depression that has not improved after at least two antidepressant tries. It may help some people by combining a brain-based treatment with ongoing daily encouragement and support.
Edmonton, AlbertaAges 18 years+ - NCT05558527Recruiting
Study of how relationships affect noticing threat cues
This study looks at how being in a stable romantic relationship changes how you notice and react to threat-related cues. It may help researchers understand factors that shape fear and alertness, which could guide future mental health treatments.
Reno, NevadaAges 18–65 - NCT05579470Recruiting
Study opioid treatment access with staff, patients, and local leaders
This study looks at how to expand opioid addiction treatment in Central Asia by gathering survey and discussion input from people with opioid dependence, people delivering treatment, and local health leadership. It may help improve how treatment programs are set up and delivered in the future.
New Haven, ConnecticutAges 18 years+ - NCT05550675Recruiting
Study of bowel leakage patterns using rectal pressure tests
This trial builds a “database” to better understand why some people have stool (faecal) leakage versus double incontinence (urine plus stool). It asks about symptoms and performs a rectal pressure test to see which factors are linked to different types of leakage.
Brussels, Brussels CapitalAges 18 years+ - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT05561205Recruiting
Brain stimulation to treat persistent apathy
This trial tests a noninvasive brain stimulation treatment (called rTMS) to help people who have had ongoing apathy (lack of motivation/interest) for at least a month. You might benefit if your apathy is persistent, your other symptoms are stable, and you meet the safety and medication rules.
Toronto, OntarioAges Any age - NCT05577247Recruiting
Study of new thinking skills in hard-to-treat depression
This trial looks at how people with treatment-resistant major depression respond when starting a new depression medicine that affects glutamate signaling. It also involves brain scans and thinking/learning tasks, aiming to understand what helps people improve when standard treatments haven’t worked.
ParisAges 18–70 - NCT05574127Recruiting
Brief behavioral therapy for depression in older cancer survivors
This study tests a brief behavioral activation program to help older cancer survivors with depression. It involves 10 sessions (or a shorter version) to improve mood and quality of life.
New York, New YorkAges 65 years+ - NCT05591820Recruiting
Brief parent training for kids’ behavior at home
This study tests a short program that helps parents manage challenging behaviors in daily life. It may help families teach consistent routines and responses to behaviors like hyperactivity, impulsivity, inattention, or opposiveness.
Groningen, Provincie GroningenAges 2–11 - NCT05565352Enrolling by invitation
Ketamine safety study for people in inpatient psychiatric care
This trial looks at whether ketamine is safe and well-tolerated for certain mental health conditions when given in a hospital setting. It may help teams better understand side effects and comfort for people who may be offered ketamine.
GdanskAges 18–90 - NCT05562557Recruiting
Fatherhood program to improve outcomes and support families
This study partners with fathers to help improve family outcomes, especially when there are worries about substance use in the household. You may be able to join if you are a father caregiver and your family has an identified risk for substance use, and you speak English or Spanish.
The Bronx, New YorkAges 18 years+ - NCT05561153Enrolling by invitation
Study of knee movement issues in patellofemoral pain
This study looks at how the nerves and muscles are working in people with patellofemoral pain (pain around the kneecap). It may help researchers understand what drives the pain and how it might be treated.
AnkaraAges 18–40 - NCT05573490Recruiting
Lifestyle program study for early-onset Alzheimer’s
This study tests a structured lifestyle intervention to help people with early-onset Alzheimer’s disease. It is designed for adults with confirmed Alzheimer’s-related brain changes, and may help with symptoms or day-to-day functioning.
Indianapolis, IndianaAges 40–75 - NCT05569018Recruiting
Spanish blended group therapy for anxiety and depression symptoms
This study tests whether a group therapy program delivered in both online and in-person formats can reduce emotional symptoms like anxiety and depression. If you qualify, you may be assigned to receive this structured group treatment during the study period.
Castellon, CastellónAges 18 years+ - NCT05576090Recruiting
Study tests sleep skills in UCLA students with insomnia symptoms
This study looks at whether sleep techniques can improve sleep problems. It’s designed for UCLA students living on campus who report meaningful insomnia symptoms, and it may help you learn practical ways to sleep better.
Los Angeles, CaliforniaAges 18–22 - NCT05563805Recruiting
Virtual reality adventure training for movement and fitness
This study uses a virtual reality “adventure” game that gets you moving to train exercise skills and coordination. It’s designed for U.S. military veterans who can walk on their own and don’t have certain vision, balance, or medical limits.
Arlington, TexasAges 18–45
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.