Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,957 recruiting studies in this area right now.
By phase
- Not applicable1,542
- Phase 2142
- Phase 384
- Phase 181
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma73
- Periodontal Diseases50
- Dental Caries45
- Head and Neck Cancer35
- Gingivitis33
- Oral Cancer31
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,957 total
- NCT07778134Recruiting
Personalized storybook for better dental visits in children
This study tests whether a personalized storybook (created with AI) helps reduce anxiety and improve cooperation in children during dental fillings. It may help kids who are nervous about dental visits feel more at ease.
EskişehirAges 4–7 - NCT07781566Recruiting
Speech therapy intensity for cleft palate speech errors in children
This study looks at how well two different intensities of speech therapy work for children with a cleft palate who have speech sound errors. It aims to find the best way to help your child speak more clearly.
Ghent, East-FlandersAges 4 years+ - NCT07779148Recruiting
Comparing irrigation methods for repeat root canal treatment
This study compares different ways of cleaning the root canal during a repeat root canal treatment. You may qualify if you have a single-rooted tooth with a failed root canal and are generally healthy.
MinyaAges 13–60 - NCT05845723RecruitingPhase 2
Study drugs for blood-vessel Behçet’s to reduce inflammation
This Phase 2 trial tests tocilizumab and tofacitinib to see if they can better control vascular (blood-vessel) Behçet’s syndrome. It may help by lowering inflammation and reducing complications from aneurysms in the aorta or peripheral arteries.
Beijing, Beijing MunicipalityAges 18–65 - NCT06558955Recruiting
Preventing baby tooth decay with text support for new moms
This study tests a program that uses text messages and online support to help new moms prevent cavities in their baby's teeth. It provides tips and support from other parents to make dental care easier for your little one.
SingaporeAges 21 years+ - NCT06559605Recruiting
Comparing 3D Zirconia Barrier vs Titanium Mesh for Bone Growth
This study tests a new 3D-printed zirconia barrier to see if it helps grow bone better than a standard titanium mesh. It may be an option if you need more jawbone for dental implants.
CairoAges 20–70 - NCT07768189RecruitingPhase 3
Testing CRB-701 for throat cancer that returned
This study tests an investigational drug called CRB-701 to see if it can help people with a certain type of throat cancer that has not responded to standard treatments. The trial compares CRB-701 to a doctor's choice of other available treatments.
Huntsville, AlabamaAges 18 years+ - NCT07773389Recruiting
Early vs late premolar removal for braces
This study compares removing two back teeth early versus later during braces treatment to see which timing leads to better tooth movement. It may help teens and young adults needing braces for crowded teeth or overbite.
IslamabadAges 13–25 - NCT07775378Recruiting
Boron and inflammation in gum disease
This study looks at how boron levels, oxidative stress (cell damage), and inflammation (swelling) relate to periodontitis (severe gum disease). It may help understand what causes gum disease and could lead to better treatments.
Istanbul, MaltepeAges 18–65 - NCT07770256Recruiting
Bone regeneration surgery for lower molar gum disease
This study looks at the shape of lower molar teeth with a certain type of gum disease and tests a surgical treatment to help regrow the bone around those teeth. If you have advanced gum disease and a lower molar with a specific type of bone loss, this treatment might help save the tooth.
Ho Chi Minh CityAges 18 years+ - NCT07775365Recruiting
AI predicts gum coverage from photos
This study uses an artificial intelligence (AI) system to look at close-up photos of your gums and predict how well a gum graft procedure might work to cover receded gums. It aims to help doctors plan your treatment more accurately.
Istanbul, IstanbulAges 18–65 - NCT07767682Recruiting
Deeper gum sulcus after mouth surgery
This trial tests whether adding a special absorbent dressing helps the mouth heal after surgery to deepen the gum area. It may help people who have shallow gum sulcus and need more space for dentures.
Izmir, ÇiğliAges 18–70 - NCT07767084Recruiting
Sealer type and pain after root canal treatment
This study compares two types of dental sealers (materials used to fill the root canal) to see if one causes less pain after the procedure. It may help you know what to expect and allow you to choose a treatment that reduces discomfort.
MinyaAges 18–45 - NCT07771296Recruiting
Using smart technology to improve diagnosis of jaw muscle pain
This study uses machine learning and MRI scans to better diagnose jaw muscle pain, which could lead to more tailored treatments. If you have persistent jaw pain that hasn't responded to basic painkillers, this trial might help you find a clearer diagnosis.
New Taipei City, SanxiaAges 18–70 - NCT06567535Recruiting
Nerve-sparing surgery for jaw cysts using a camera and navigation
This trial tests a new way to remove jaw cysts using a tiny camera and special guides, which may help protect the nerve in your jaw. It is for people with a tooth-related cyst at least 2 cm wide that is pushing on that nerve.
Guangzhou, GuangdongAges 18–75 - NCT06574477Recruiting
Mixed-reality tech for impacted canines
This trial tests whether a new mixed-reality technology helps guide an impacted canine tooth into the correct position. It may be a good option if you have a canine that is stuck high up in the roof of your mouth and you are already in braces to make room for it.
KrakowAges 10–20 - NCT06576986Recruiting
Can a supplement prevent mouth sores during chemo?
This trial tests whether a special supplement (synbiotic) can prevent mouth sores caused by chemotherapy in people with colorectal cancer. It's for those starting treatment who live in or near Belo Horizonte, Brazil.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT07759843Recruiting
Using AI to evaluate treated gummy smiles
This trial is testing whether artificial intelligence can help evaluate and guide the treatment of gummy smiles. If you've already had successful treatment for a gummy smile, your case may help improve AI tools for future patients.
Cairo, Cairo GovernorateAges 18 years+ - NCT07758725Recruiting
Jaw repositioning surgery and joint remodeling
This study looks at how the way your lower jaw is repositioned during corrective jaw surgery affects the natural reshaping of the jaw joint over time. The goal is to help improve long-term joint health and stability after surgery.
Istanbul, FatihAges 18–65 - NCT07762651Enrolling by invitation
Tooth-colored fillings for back teeth compared
This study compares two types of tooth-colored filling materials for back teeth. It aims to see which one lasts longer and works better.
Tanta, TantaAges 25–40 - NCT07763808RecruitingPhase 2/Phase 3
Gum surgery for receding gums after braces
This study tests different surgical methods to repair receding gums that can happen after orthodontic treatment. If you have gum recession and are otherwise healthy, this trial may help improve your gum health and appearance.
BakuAges 18–70 - NCT07760974Recruiting
Comparing two surgical guides for placing front tooth implants
This study compares two types of 3D-printed guides used during dental implant placement in the front of the mouth. The goal is to see if a new guide (SocketFit) is more accurate than the standard one, which could lead to better implant positioning and outcomes.
Tanta, Gharbia GovernorateAges 18–35 - NCT07765745Recruiting
Thymoquinone gel for preserving jawbone after tooth removal
This study tests a gel made from thymoquinone, a compound found in black seed, to see if it helps preserve the bone where a tooth was removed. It may help keep the jawbone strong for future dental work.
Kafr ash Shaykh, KafrelsheikhAges 18–50 - NCT07759349RecruitingEarly Phase 1
Pain relief choices after root canal treatment
This study compares three different pain relievers to see which works best for pain after a single-visit root canal. It may help find better ways to manage post-procedure discomfort.
Karachi, SindhAges 18–60
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,957 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,729 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.