Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT07627295Recruiting
Filling Materials and Polishing for Front Tooth Cavities
This study compares two types of tooth-colored filling materials and different polishing techniques for cavities on the front surfaces of teeth near the gum line. The goal is to see which combination works best and lasts longest over 2 years.
Al Mansurah, Dakahlia GovernorateAges 18–35 - NCT06435780Recruiting
New gum graft technique for ridge repair
This trial tests a new, less invasive method to repair the gum ridge where a premolar tooth is missing. It compares the new technique to the standard gum graft procedure, with the goal of improving the area so a future dental implant or bridge can be placed.
CairoAges 18–50 - NCT06393699Recruiting
Comparing fillings for worn spots on teeth
This study tests two types of tooth-colored fillings and a special glue for repairing worn spots on the sides of teeth near the gumline. It aims to see which material works best and lasts longest.
CairoAges 18–65 - NCT07632547Recruiting
Video Help for Anxious Children at the Dentist
This study tests whether watching a video before dental treatment helps children feel less scared at the dentist. Researchers will compare a new video-based teaching method to standard care for children aged 4–6 who need simple fillings or tooth repairs.
DamascusAges 4–6 - NCT06238076Recruiting
Universal surgical device for jaw reconstruction
This trial tests a universal surgical device for rebuilding the lower jaw using a bone flap from the leg. It aims to make the procedure more reliable and easier for patients needing reconstruction of the front part of the jaw.
ToulouseAges 18 years+ - NCT07034079RecruitingPhase 2
Adding ridges to dentures for better fit and comfort
This study tests adding small ridges (called palatal rugae) to a complete upper denture to see if it makes patients more satisfied and improves their quality of life related to oral health. It may help dentures feel more natural and stable.
Islamabad, IslamabadAges 40–80 - NCT06312085Recruiting
Root canal study with new filling material
This study tests a new material for filling root canals after cleaning out an infection. It aims to see if the material helps the tooth heal successfully. You may qualify if you have an infected tooth that has never had a root canal before.
IstanbulAges 18–75 - NCT06276335Recruiting
Timing of dental implant placement and early healing
This trial compares placing a dental implant right after a tooth is pulled versus waiting for the socket to heal first. It aims to see which timing leads to better healing at the molecular level.
LondonAges 25 years+ - NCT07488416Recruiting
Ginger paste vs. antibiotics for infected baby molars
This study tests a new paste made from zinc oxide and gingerol (a ginger extract) to treat infected baby molars. It may be an alternative to the standard antibiotic paste, with fewer antibiotics and potentially fewer side effects.
CairoAges 4–8 - NCT07273552Recruiting
Root control in 3D-printed clear aligners
This study tests a new type of 3D-printed clear aligner and how well it can control the way teeth roots move. It may be a good option if you have gaps in your teeth (not crowding) and do not need any tooth extractions.
Banī SuwayfAges 18–45 - NCT07634900Recruiting
Pain relief methods for children's emergency tooth root treatment
This study compares two different numbing techniques used during emergency root canal treatment in children's back lower teeth. Researchers want to see which method works better at relieving pain during the procedure.
Malatya, MalatyaAges 6–14 - NCT06946693Recruiting
Surface smoothness and color of temporary dental crowns compared
This study compares temporary dental crowns made in three different ways: the usual method, 3D printing, and milling from a block. If you need a dental implant, this trial will see which type of temporary crown stays smooth and doesn't change color over time.
Rohtak, HaryanaAges 20–60 - NCT07696702Recruiting
Comparing pulp capping for deep cavities in adult back teeth
This study tests two ways to treat deep cavities that reach the nerve of the tooth, to see which helps the nerve heal better. It may be an option if you have a deep cavity in a lower molar and the nerve is still healthy.
Rohtak, HaryanaAges 18–40 - NCT07613606Recruiting
Platelet-Rich Fibrin Injection for Gum Disease Treatment
This study tests a new injectable treatment using your own blood cells to help repair damaged gum tissue and bone around teeth affected by periodontal disease (gum disease). The goal is to see if this minimally invasive approach can regenerate healthy gum and bone without major surgery.
CairoAges 18 years+ - NCT07641725Recruiting
Light Therapy and Steroid Rinse for Pemphigus Mouth Sores
This study tests whether a steroid mouthwash and/or light therapy (photobiomodulation) can help heal painful mouth sores caused by pemphigus vulgaris, an autoimmune disease that damages the inside of the mouth and skin.
DamascusAges 18–80 - NCT07384403RecruitingPhase 4
Oxygen therapy around healing collar after surgery
This trial tests whether a topical oxygen therapy applied around a customized healing collar helps improve healing after dental implant surgery. It is for adults in good health who are ready to commit to follow-up visits.
CairoAges 21 years+ - NCT07515937Recruiting
3D-Printed Bite Splint for Broken Jaws in Children
This study tests a custom 3D-printed bite splint to help heal straightforward jaw fractures in children aged 6–12. Instead of surgery, the splint guides the broken pieces back together while your child heals naturally.
Cairo, Cairo GovernorateAges 6–12 - NCT06677125Recruiting
Magnetic mallet and special drill for sinus lift in dental implants
This study tests two tools (a magnetic mallet and a special drill) used to lift the sinus floor during dental implant placement in the upper jaw. It may help people who need implants but have limited bone height.
AlexandriaAges 30–60 - NCT07523815RecruitingPhase 4
AI-Assisted versus Standard Planning for Dental Implants
This study compares using artificial intelligence computer planning versus standard planning methods for placing a single dental implant in your back teeth. The goal is to see if AI planning makes the implant placement faster, easier, and more precise.
Cairo, ManialAges 18–50 - NCT07242313Recruiting
Comparing two types of bone graft materials for tooth socket preservation.
This trial tests whether a dentin graft (made from tooth) or a mineralized graft works better for preserving the jawbone after a tooth is removed in the upper back area. Your participation could help doctors find the best way to keep the bone strong and ready for future implants.
Kafr ash ShaykhAges 18–60 - NCT06683560Recruiting
3D-printed aligners for cleft lip and palate repair
This study tests whether custom 3D-printed aligners can help shape a baby's cleft lip, gum, and palate before surgery. It aims to make traditional molding treatment more precise and easier for families.
Cairo, AbbasyaAges Up to 1 month - NCT07526272Recruiting
Magnesium membrane versus bone graft for tooth implants
This study compares two methods to rebuild bone around immediate tooth implants (implants placed right after tooth extraction). The goal is to see which material—a magnesium membrane or bone graft—works better to support the implant and maintain bone structure.
GizaAges Any age - NCT07532200Recruiting
Pain genes and inflammation in tooth root canal treatment
This research study examines how your genes affect pain and inflammation when you have a painful tooth that needs root canal treatment. By studying these responses, researchers hope to better understand why some people experience different levels of pain during dental procedures.
New Delhi, National Capital Territory of DelhiAges 18–50 - NCT07533110RecruitingPhase 4
NOVAMag Shield for tooth extraction and implant placement
This study tests a new bone-grafting material (NOVAMag® SHIELD) used during tooth extraction and immediate dental implant placement in visible areas of the mouth. The goal is to help the bone heal better around your new implant.
Almada, Setúbal DistrictAges Any age
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.