Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,957 recruiting studies in this area right now.
By phase
- Not applicable1,542
- Phase 2142
- Phase 384
- Phase 181
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma73
- Periodontal Diseases50
- Dental Caries45
- Head and Neck Cancer35
- Gingivitis33
- Oral Cancer31
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,957 total
- NCT06516133RecruitingPhase 3
Online adaptive radiotherapy for nasopharyngeal cancer
This trial tests a new type of radiation therapy that adjusts in real-time to treat nasopharyngeal cancer. It is for people who have not received prior radiation and have no distant spread of cancer.
Guangzhou, GuangdongAges 18–70 - NCT06514053Recruiting
Predicting success of molar pulp treatment
This study looks at whether certain signs in your tooth can help predict if a special type of filling (pulpotomy) will work for deep cavities in back teeth. It may help find the best treatment for you.
Hong KongAges Any age - NCT06518421Recruiting
Emotions and Memory in Chronic Facial Nerve Pain
This study looks at how emotions and memory are affected in people with chronic trigeminal neuralgia (a type of facial nerve pain). Participants will have an MRI scan and fill out questionnaires to help researchers understand the link between chronic pain and cognitive changes.
Toronto, OntarioAges 35–60 - NCT06517238Recruiting
Digital tool to improve dental care during braces treatment
This trial tests a new digital communication tool that helps your dentist and orthodontist work together better. The goal is to improve how your teeth are cared for while you have braces.
ReimsAges 8–18 - NCT07792720Recruiting
Platelet-rich fibrin and hyaluronic acid for dental implant healing
This study tests whether adding platelet-rich fibrin (a substance made from your blood that helps healing) and hyaluronic acid (a natural joint and tissue lubricant) to dental implants improves healing. If you need a dental implant in your lower back teeth and are generally healthy, this might help you heal faster and more comfortably.
Sanaa, Sana'aAges 18–65 - NCT06526351Recruiting
Early implant with immediate vs. conventional loading
This trial compares two ways of placing a dental implant after a tooth is removed in the front upper jaw. One group gets the new tooth placed right away (immediate loading), and the other group waits a few months. The goal is to see which approach works better for healing and long-term success.
BelgradeAges 18 years+ - NCT06529562Recruiting
Surgery plus reduced chemo and radiation vs standard for nasopharyngeal cancer
This trial compares two approaches for people with early-stage nasopharyngeal cancer that can be removed with surgery. It tests whether giving less intense chemotherapy and radiation after surgery works as well as a standard dose, with fewer side effects.
Zhuhai, GuangdongAges 18–70 - NCT06533267Recruiting
Endoscopic surgery vs. radiation for early-stage nasal cancer
This trial compares two treatments for stage I nasopharyngeal cancer (a type of nasal cancer). It tests whether a minimally invasive surgery (endoscopic surgery) is as good as or better than radiation therapy. It may be an option for people whose cancer is small and hasn't spread to lymph nodes.
Zhuhai, GuangdongAges 18–75 - NCT07788976Recruiting
Comparing two jaw surgery techniques for better healing
This study looks at two different ways of doing jaw surgery to see which one gives better stability and healing. If you are already planning to have jaw surgery, this study may help improve how well your jaw stays in place after the procedure.
Istanbul, FatihAges 18–65 - NCT07790315Recruiting
Clear aligner comfort study for mild to moderate crowding
This study tests two types of clear aligners to see which one feels more comfortable and works better for patients with mild to moderate crowding. It may help decide which aligner material is better for future patients.
Lahore, Punjab ProvinceAges 15–30 - NCT07787949Recruiting
Platelet-rich fibrin injection for gum bone defects
This study tests a new way to treat a specific type of gum disease that causes bone loss around the roots of back teeth. It uses your body's own healing factors (from a blood sample) to help the bone and gum reattach, without surgery.
Giza, Giza GovernorateAges 18 years+ - NCT05650359Recruiting
Light therapy study for braces alignment in adults
This trial studies whether Orthopulse light therapy (a form of light treatment) can help during orthodontic treatment with fixed braces. It’s for adults who need braces for crowded front lower teeth, and it will compare outcomes during the alignment phase.
Chandler, ArizonaAges 18 years+ - NCT05933889Recruiting
Study of robotic throat surgery for early oropharyngeal cancer
This study looks at how well different robotic surgery approaches work for people with early oropharyngeal squamous cell carcinoma (throat cancer). You may be asked for consent for extra tissue and imaging analysis to help researchers understand patterns related to outcomes.
LondonAges 18 years+ - NCT05892354Recruiting
Immunonutrition to reduce mouth sores after cancer treatment
This trial studies whether special nutritional supplements (immunonutrients) can reduce painful mouth sores (oral mucositis) in people with nasopharyngeal cancer after chemoradiotherapy. If you qualify, you’ll be followed with visits and lab tests to see if the supplements improve comfort and recovery.
Fuzhou, FujianAges 18–70 - NCT05161091Recruiting
Orosol® mouth treatment for chemo or radiation mouth sores
This trial tests whether Orosol® can reduce mouth sores caused by chemotherapy or radiation. If you have moderate to severe mouth sores from these treatments, it may help improve comfort and healing.
Clermont-FerrandAges 18 years+ - NCT07779564Recruiting
Electric flosser study for plaque and gum health
This study tests whether an electric flosser is better than a manual toothbrush for reducing plaque and gum inflammation. Participants will use the electric flosser for 30 days while having regular checkups. This could help you learn a new way to improve your oral health.
Fort Wayne, IndianaAges 18–70 - NCT05382585Recruiting
Study of new treatment targets for head and neck cancers
This study looks at new ways to target head and neck cancers. It may help researchers learn which treatment ideas could work better for people with these cancers.
Varanasi, Uttar PradeshAges 18–100 - NCT07776756Recruiting
Gum tissue repair for molar furcation defects
This trial tests whether a special enamel protein combined with bone graft material can help repair gum and bone damage around the roots of back teeth (molars). It may improve the health of the area and reduce the need for more serious treatments.
Ho Chi Minh City, Binh PhuAges 18 years+ - NCT07776912Recruiting
Tooth fillings for cavities in children's back teeth
This study compares three types of tooth-colored fillings for cavities in the back teeth of children aged 4-9. It looks at how well they work, their effect on bacteria in the mouth, and how they affect saliva acidity, aiming to find the best option for kids.
CairoAges 4–9 - NCT07779421Recruiting
Healing bone after wisdom tooth removal
This study tests whether using a patient's own blood products can help bone heal better after removing a wisdom tooth. It may help reduce the gap left behind and protect the nearby molar.
Fuzhou, FujianAges 18–60 - NCT07781566Recruiting
Speech therapy intensity for cleft palate speech errors in children
This study looks at how well two different intensities of speech therapy work for children with a cleft palate who have speech sound errors. It aims to find the best way to help your child speak more clearly.
Ghent, East-FlandersAges 4 years+ - NCT07780760Recruiting
Numbing throat spray to ease pain after tonsil removal in children
This study tests whether a numbing mist sprayed into the throat before surgery can reduce sore throat pain children feel after having their tonsils removed. It compares two numbing medicines to see if one works better than the other.
Al FayyumAges 3–15 - NCT07782125Recruiting
Gum graft alternatives for dental implants
This study compares two ways to add gum tissue around a dental implant to improve its appearance and health. One method uses a small piece of your own gum tissue, and the other uses a special collagen material.
Ankara, Yeni̇mahalleAges 18–65 - NCT07778199Recruiting
Implant denture fitting: digital vs traditional dental impressions
This trial compares two ways of taking dental impressions (molds) for making a full-arch implant-supported denture. One method uses a digital scanner, the other uses traditional dental putty. The goal is to see if one results in a more comfortable and precise fit.
Al Mansurah, Dakahlia GovernorateAges 35–70
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,957 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,729 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.