Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT07534423Recruiting
Finishing teeth after braces removal training
This study teaches dental professionals best practices for completing and polishing teeth immediately after braces are removed. It's designed for orthodontists and dentists who work with braces to improve their finishing techniques.
Roma, RMAges Any age - NCT05315791Recruiting
Bone-window dental procedure for missing back upper tooth
This study looks at how to place bone support for an upper back tooth replacement when part of the upper jaw bone is limited. If you’re missing one upper back tooth for at least 3 months, they may use a specific “bone window” approach guided by a 3D scan.
Hangzhou, ZhejiangAges 18–80 - NCT07535060Recruiting
Growing bone at tooth gap sites with or without bridge
This study tests whether bone can be developed at the site of a missing tooth in your smile zone, with or without a temporary tooth bridge. The goal is to improve the site for a future implant or bridge.
CairoAges 18 years+ - NCT07107100Recruiting
Comparing two types of retainers after braces
This study compares two types of retainers (a wire that keeps teeth in place) after braces are removed: one that is directly bonded to the teeth and one that is made indirectly. It looks at which type keeps gums healthy, lasts longer, and how likely it is to break.
Karachi, SindhAges 13–40 - NCT07624331Recruiting
PEEK vs. Standard Healing Caps for Tooth Implants
This study compares two types of temporary healing caps (PEEK and standard materials) used during dental implant surgery for a single back tooth. Researchers will measure how well the gum tissue heals around each type to see which works better.
Sungai Buloh, SelangorAges 18 years+ - NCT07215598Enrolling by invitation
Comparing Invisalign attachments on opposite sides of the mouth
This study tests how well Invisalign attachments work by comparing two different attachment designs placed on opposite sides of the mouth. It aims to find which type of attachment is more effective for moving teeth.
Baltimore, MarylandAges 18 years+ - NCT07536399RecruitingPhase 3
Bone Marrow Treatment for Jaw Joint Pain Relief
This study tests whether injecting your own bone marrow cells into your jaw joint during a minimally invasive procedure can reduce pain and improve jaw function better than arthroscopy alone. It's for people with significant jaw pain that hasn't improved with conservative treatments like NSAIDs, physical therapy, and bite splints.
New York, New YorkAges 18–75 - NCT07683650Recruiting
Hyaluronic acid and platelet gel for jaw joint disc pain
This study tests a mixture of hyaluronic acid (a natural lubricant) and platelet-rich fibrin (from your own blood) injected into the jaw joint to see if it helps people with a misaligned jaw disc and pain. It may improve jaw movement and reduce discomfort.
Al MansurahAges 18–45 - NCT05997186Recruiting
Reinnervated flap for mouth and throat reconstruction
This trial tests a new way to rebuild parts of the mouth or throat after surgery, using a flap from the thigh that is reconnected to nerves to help it work better. It may help people who need a reconstructive procedure for these areas.
BaselAges 18 years+ - NCT06187337Recruiting
Expanding the upper jaw to fix crowded front teeth in children
This trial tests if expanding the upper jaw can make room for crowded front teeth in children who still have some baby teeth. It aims to help the side front teeth come in properly without needing braces later.
CoppitoAges 6–16 - NCT06724133Recruiting
Mouth bacteria and colon polyps study
This study looks at the bacteria in your mouth and how they might be linked to colon polyps. Researchers want to see if certain mouth bacteria affect the body's immune system and increase the risk of polyps.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07552441Recruiting
Mouth Muscle Pressure and Upper Jaw Width Study
This study examines how the muscles around your mouth affect the width of your upper jaw. Researchers will measure the pressure your mouth muscles create to better understand jaw development and may help improve orthodontic treatment in the future.
Van, VanAges 12–25 - NCT07191158Recruiting
Testing a 3D-printed molar-moving device for bite correction
This trial is testing a new 3D-printed device that moves your upper molars backward to correct a specific type of bite problem (Class II). It may help you if you have a clear overbite on both sides and your second molars are already in place.
Baghdad, Al-RussafaAges 16–30 - NCT07192146Recruiting
Patient experiences after dental emergency treatment
This study looks at how patients feel after receiving emergency dental treatment for tooth pain. It aims to understand what factors affect their recovery and satisfaction.
BangkokAges 18 years+ - NCT07548203Recruiting
Treatments for Dark Spaces Between Teeth
This study tests different ways to fix dark triangular gaps that appear between teeth below the gum line. These gaps can affect how your smile looks and may trap food. The trial will compare treatment options and follow your results over 6 months.
CairoAges 18–50 - NCT07187609Recruiting
Zinc bone graft for tooth replacement implants
This trial tests a special bone graft material made from cow bone with zinc to help support a new dental implant placed right after a tooth is removed. It may help people who need a tooth replaced in their lower jaw.
SuezAges 21–50 - NCT07548398Recruiting
Gummy Smile Study: Gum and Tooth Position Research
This study looks at why some people show a lot of gum when they smile and how their teeth erupt (come in). Researchers want to understand how common these conditions are and what factors influence them.
Roma, RMAges 18–50 - NCT07074730Recruiting
Anesthesia types for urethral surgery
This trial compares general anesthesia versus spinal anesthesia with local numbing medicine for penis skin graft surgery. It aims to see which method works better for pain control and recovery.
Tanta, El-GharbiaAges 21 years+ - NCT07082244Recruiting
Gum and bone shaping for dental implants
This study tests a procedure to improve the shape of the gum and bone around a dental implant in people with thin gums. It uses a special graft material to make the area thicker and more stable for a better-looking result.
Ann Arbor, MichiganAges 18 years+ - NCT06975358Recruiting
Faster braces with gum surgery and growth factor injections
This study tests if a small gum surgery (alveolar decortication) plus a natural growth factor injection (CGF) can speed up tooth movement in people who need braces and have two teeth removed. It may help you have a shorter treatment time.
Tanta, TantaAges 16–22 - NCT07386366Recruiting
Testing triclosan-coated stitches for wisdom tooth surgery healing
This trial compares how well wounds heal after removing impacted wisdom teeth using stitches coated with triclosan (a germ-fighting agent) versus regular stitches. It aims to see if coated stitches reduce bacteria and improve healing.
Ho Chi Minh CityAges 18–35 - NCT06497244Recruiting
Micro-holes in bone to speed molar movement
This trial tests whether tiny holes made in the bone (micro-osteoperforation) can speed up moving your upper back molars backward using a device anchored to bone. It is for adults with a specific bite problem (Class II on both sides) who are healthy and have all their teeth.
CairoAges 16 years+ - NCT07166679Recruiting
Larger root canal tip for healing infection in back molars
This study tests whether making the tip of the root canal slightly larger during a single root canal treatment helps the infection heal better and reduces pain afterward. It is for people with a dead lower back molar that has an infection around the root tip.
RohtakAges 18–65 - NCT07091422Recruiting
Testing a new brace glue: does it hold better?
This trial tests a new no-etching glue for braces. Half of your mouth will get the new glue, the other half a standard glue, to see which one holds the brackets better over a year.
Baltimore, MarylandAges 14–35
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.