Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,957 recruiting studies in this area right now.
By phase
- Not applicable1,542
- Phase 2142
- Phase 384
- Phase 181
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma73
- Periodontal Diseases50
- Dental Caries45
- Head and Neck Cancer35
- Gingivitis33
- Oral Cancer31
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,957 total
- NCT07762651Enrolling by invitation
Tooth-colored fillings for back teeth compared
This study compares two types of tooth-colored filling materials for back teeth. It aims to see which one lasts longer and works better.
Tanta, TantaAges 25–40 - NCT07760974Recruiting
Comparing two surgical guides for placing front tooth implants
This study compares two types of 3D-printed guides used during dental implant placement in the front of the mouth. The goal is to see if a new guide (SocketFit) is more accurate than the standard one, which could lead to better implant positioning and outcomes.
Tanta, Gharbia GovernorateAges 18–35 - NCT07761442Recruiting
Comparing two methods for placing dental implants right after tooth removal
This study tests two ways of placing a dental implant immediately after pulling a tooth to see which one better preserves the bone and gum. It might help people who need a front tooth replaced and want to keep the area looking natural.
MinyaAges 20–60 - NCT07762482Recruiting
Surgical correction for gummy smile
This study tests a surgical procedure to correct a gummy smile caused by a specific gum condition. It aims to see if the gum tissue stays stable after surgery.
Ribeirão Preto, São PauloAges 18 years+ - NCT07762976RecruitingPhase 2
Tailoring chemo for nasopharyngeal cancer using EBV-DNA and MRI
This trial tests whether adjusting chemotherapy based on tumor markers (EBV-DNA) and MRI scans can improve outcomes and reduce side effects for people with nasopharyngeal cancer. If you have stage II or III disease, this study might help guide your treatment more precisely.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT01885299Recruiting
Long-term registry for stereotactic radiation treatments
This study collects long-term information from people who receive stereotactic radiosurgery or stereotactic body radiotherapy for tumors or other conditions. It helps researchers understand how these precise radiation treatments work over time.
Colorado Springs, ColoradoAges Any age - NCT05517135Recruiting
Personalized treatment for EBV-positive nasopharyngeal cancer
This trial tests a “choose the best treatment” approach for people with nasopharyngeal cancer (NPC) that is linked to EBV (a common virus). By matching treatment to your EBV and cancer features, the study aims to improve outcomes while tracking safety.
SingaporeAges 21–99 - NCT04498221Recruiting
Mapping lymph flow in oropharyngeal cancer with scans
This study uses a special dye or tracer to map how lymph fluid travels from an oropharyngeal (throat) cancer to nearby lymph nodes. It may help doctors understand the most likely spread pattern and plan future treatment more accurately.
LondonAges 18 years+ - NCT07752498Enrolling by invitation
Long-term results from twin block treatment
This study checks whether the results from an earlier treatment with the Twin Block appliance, which corrects bite problems, hold up over time. It looks at how stable the teeth and jaw remain years after treatment.
Jönköping, Jönköping CountyAges Any age - NCT07750561Enrolling by invitation
Turkish questionnaire for facial synkinesis
This study tests a Turkish version of a questionnaire that measures abnormal facial movements (synkinesis) that can happen after facial palsy. It aims to see if the questionnaire works well for Turkish-speaking patients.
Istanbul, CevizlibağAges Up to 18 years - NCT07750392Recruiting
Dry needling and gentle laser therapy for recent neck pain
This trial tests two therapies—dry needling (thin needles into muscle knots) and low-level laser/microcurrent (gentle energy) treatment—alone or combined, to relieve acute neck pain from muscle knots (myofascial pain). It aims to reduce pain and improve function for people with recent onset symptoms.
Denpasar, BaliAges 20–45 - NCT07752849Recruiting
Platelet-rich fibrin gel for cleft palate repair
This study compares two types of gel made from the patient's own blood, with or without an antibiotic, applied during cleft palate surgery to see if they improve healing and reduce complications.
SanaaAges 3 months–18 years - NCT07755800Enrolling by invitation
Arginine toothpaste for gum health in periodontitis patients
This study tests whether an arginine-containing toothpaste improves gum health in people with treated periodontitis during their maintenance care. It may reduce gum inflammation and promote better bacterial balance below the gumline.
Iowa City, IowaAges 18–95 - NCT07751211Recruiting
Laser and gel treatment after gum graft surgery
This study tests whether a special light treatment (laser) plus a natural gel (hyaluronic acid) can help your gums heal better after a free gingival graft — a procedure to cover exposed tooth roots and increase gum tissue.
Istanbul, BakırköyAges 18 years+ - NCT07754253RecruitingPhase 1
Green tea extract for gum disease treatment
This trial tests a green tea extract (EGCG) as an add-on to standard gum disease treatment, delivered locally to the gums. It aims to see if this natural compound can help improve gum health more effectively than standard care alone.
Al Mansurah, Dakahlia GovernorateAges 25–60 - NCT07750171Recruiting
How smoking affects healing around dental implants
This study looks at how smoking affects the body's immune response around dental implants that are healthy or have mild gum disease. It may help us understand why some implants develop problems and could lead to better care for smokers with implants.
Ankara, AnkaraAges 21–75 - NCT06593925Recruiting
Snap-on denture made from a strong plastic for older adults
This trial tests a new plastic material (polyoxymethylene) to make a telescopic denture—a partial denture that snaps onto your remaining teeth. It is for people aged 65 and older who have lost several teeth but still have some healthy teeth to support the denture.
BelgradeAges 65–100 - NCT06587971Recruiting
Intensive gum treatment for aortic stenosis
This trial tests whether intensive gum disease treatment can improve health in people with aortic stenosis (a narrowed heart valve). If you have both gum disease and mild-to-moderate aortic stenosis, you may be able to join.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07749586RecruitingPhase 1/Phase 2
Study of ARV-6723 alone or with pembrolizumab for advanced solid tumors
This trial tests an experimental drug called ARV-6723, alone or with another drug called pembrolizumab, for people with advanced solid tumors that have not responded to other treatments. The goal is to see if these combinations can help shrink tumors or slow their growth.
New York, New YorkAges 18 years+ - NCT07746206RecruitingEarly Phase 1
Insulin vs hyaluronic acid gel for advanced gum disease
This study compares two treatments applied directly to the gums to see which one better helps severe gum disease (periodontitis) heal. If you have advanced gum disease and haven't had treatment recently, you may be able to join.
CairoAges Any age - NCT07744776Recruiting
Dental implant design and stability for lower molar replacements
This study tests two different designs and surface treatments of dental implants to see which one is easier to place (insertion torque) and which becomes stable faster (implant stability quotient, a measure of how well the implant holds in the bone). If you need a dental implant in a lower molar and have healthy gums, you may be able to join.
VilniusAges 18 years+ - NCT07747350Recruiting
Laser vs pain pills for braces pain in Malay women
This study compares a low-level laser treatment with standard painkillers to see which works better for reducing pain from getting braces. It is for Malay women aged 18-33 who have never had braces and are generally healthy.
Kota Bharu, KOTA BHARUAges 18–33 - NCT07748676Recruiting
Comparing two rinsing solutions for deep cavities with tooth pain
This study tests whether rinsing the inside of a painful tooth with a special solution (calcium hypochlorite or sodium hypochlorite) after removing the damaged nerve tissue helps preserve the tooth and reduce pain. It's for people with a deep cavity causing severe toothache, and may help avoid a root canal or tooth loss.
Rohtak, HaryanaAges 18–40 - NCT06611150RecruitingPhase 1
Chemo and radiation for advanced nasopharyngeal cancer
This trial tests whether a specific chemotherapy drug (nab-paclitaxel) given along with targeted radiation therapy can help people with stage III or IVa nasopharyngeal cancer. The goal is to improve treatment outcomes while managing side effects.
Guangzhou, GuangdongAges 18–70
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,957 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,729 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.