Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT05707780Recruiting
Testing resin-ceramic crowns for back teeth
This study tests a new type of crown made from resin and ceramic for molars or premolars. If you need a back-tooth crown and your mouth health is in good shape, you may be asked to receive and have it evaluated over time.
MadridAges 20–80 - NCT07318298Recruiting
Hyaluronic acid injection for wisdom tooth socket healing
This trial tests if injecting hyaluronic acid into the sockets after wisdom tooth removal helps bone heal faster. It may be an option if you need both lower wisdom teeth removed and are generally healthy.
IrbidAges 18–35 - NCT04166695Recruiting
Testing long-lasting partial dentures for back teeth
This study looks at how well a specific type of fixed partial denture works over about 3 years. It may help people missing two back teeth next to each other by improving comfort and chewing with a stable dental replacement.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT07154693Recruiting
Bone graft after tooth extraction to prepare for implant
This study tests a bone graft material (OsteoGen®) placed in the tooth socket after extraction to help the bone heal and get ready for a dental implant. It may be right for you if you need a single tooth pulled and plan to get an implant.
San Antonio, TexasAges 18–89 - NCT06976411Enrolling by invitationPhase 4
Healing of root hole repair using different materials
This trial tests how well different materials help heal a small hole (perforation) in the root of a lower molar tooth. It may help if you have this type of tooth injury and are generally healthy.
CairoAges 15–50 - NCT06495320Recruiting
Teaching parents about safe medicine use for hospitalized children
This study tests whether teaching parents about safe and correct medicine use (rational drug use) changes their attitudes. It's for parents of children up to age 12 who are currently in the hospital and who haven't had this training before.
BilecikAges Any age - NCT07157410Recruiting
Tooth-colored onlays for cavities below the gum line
This trial tests a tooth-colored filling (onlay) for back teeth with cavities that go below the gum line. It is designed for people whose tooth is weakened but still healthy enough to avoid more serious treatments like root canals.
Al Mansurah, Dakahlia GovernorateAges 20–50 - NCT07307209Recruiting
Comparing two ways to move upper teeth backward with tiny screws
This trial compares two methods (sliding jigs vs retraction hooks) to move your upper teeth backward using small screws placed in your jawbone. It may help if you have a mild overbite or crowded upper teeth and want to avoid removing teeth.
SanaaAges 14 years+ - NCT07304752Recruiting
Probe Material Effect on Implant Gums Measurement
This study compares how different materials used for probing around dental implants affect accuracy. It is for people with a single implant (with a screw-retained crown, no abutment) that has been in use for at least a year and is either healthy or has only mild gum inflammation.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT06798090Recruiting
Comparing 3D-printed vs. traditional dental space maintainers
This trial tests two ways of making a small dental device that holds space for adult teeth when baby molars are lost early. It compares a 3D-printed version with a conventionally made one, to see which works better and is more comfortable.
Aydin, AydınAges 5–8 - NCT07303530Recruiting
Effect of printing layer thickness on fungus growth in 3D-printed dentures
This trial tests how the thickness of printing layers in 3D-printed dentures affects the growth of Candida albicans, a type of fungus that can cause infections. It aims to find the best design to keep your mouth healthier.
Cairo, Cairo GovernorateAges Any age - NCT05329558Enrolling by invitation
Testing changes in jawbone problems in adults
This study looks at what changes happen in the jawbone in people with osteonecrosis of the jaw (a damaged jawbone area), whether or not they take certain cancer/bone medicines. It may help doctors better understand the condition and how it behaves over time.
GrazAges 18 years+ - NCT07297459Enrolling by invitation
Surgery options for a jaw joint problem
This trial compares two types of surgery to treat a common jaw joint problem where the disc slips out of place. It looks at which procedure works better for reducing pain and improving function.
StockholmAges 18 years+ - NCT07294820Recruiting
Digital workflow for same-day implants
This trial tests a fully digital method for placing a single implant and attaching a temporary tooth right after extraction. It may help you avoid multiple visits and get a new tooth faster.
Turin, PiedmontAges 18 years+ - NCT07293975Recruiting
Pain relief during brace removal with TENS or vibration
This study tests two drug-free methods—gentle electrical stimulation (TENS) and high-frequency vibration—to see if they can reduce pain when braces are removed.
BaghdadAges 15–35 - NCT07376954Enrolling by invitationPhase 1
Bite correction for children with underbite
This trial tests a special dental device that is glued to the teeth to correct an underbite in children aged 8-11. It aims to improve the way the upper and lower jaws fit together.
Al MansurahAges 8–11 - NCT04552080RecruitingPhase 4
Antibiotics around sinus and bone graft implants to prevent problems
This trial studies whether taking antibiotics through the body (systemic antibiotics) after sinus-lift and bone-graft dental implant surgery can reduce post-surgery complications and improve patient comfort. It compares outcomes that matter to patients after implant placement using guided bone regeneration and a sinus floor elevation.
GrazAges 21 years+ - NCT07344025Recruiting
Comparing two bone graft materials for tooth socket preservation
This trial tests two different bone graft materials used to preserve the jawbone after a tooth extraction. The goal is to see which material works better to maintain bone for future dental implants.
AlexandriaAges 21–50 - NCT06806241Recruiting
Tranexamic Acid Rinse for Wisdom Tooth Removal
This trial tests rinsing the surgery area with a medicine called tranexamic acid to see if it helps reduce bleeding and swelling after wisdom tooth removal. If you need both of your lower wisdom teeth out, this study might help your recovery.
Istanbul, FatihAges 14–40 - NCT06808854Recruiting
Comparing two types of dental implants for a missing back tooth
This trial compares two types of dental implants (variable-thread and standard) for replacing a single missing back tooth. It aims to see which implant works better for long-term stability and healing.
DubaiAges 18 years+ - NCT07282977Enrolling by invitation
Comparing methods to move gums for a front crown
This trial compares three ways to temporarily push the gums away from a tooth so a dentist can take an accurate mold for a single front crown. It is for people with healthy gums and a crown margin that sits slightly below the gumline.
Zhengzhou, HenanAges 18 years+ - NCT07282483RecruitingPhase 2
Chinese medicine mouthwash for radiation mouth sores
This trial tests whether a traditional Chinese medicine mouthwash and oral liquid can help prevent or reduce mouth sores caused by radiation therapy for head and neck cancer. If you are getting radiation and are at risk for these painful sores, this study might offer you extra relief.
Chengdu, SichuanAges 18–65 - NCT06305000Recruiting
Gum tissue addition for implant gum inflammation treatment
This study tests whether adding extra gum tissue (keratinized mucosa) around a dental implant can improve treatment results for inflamed gum tissue around the implant (peri-implant mucositis). It is for people with a single, healthy implant that has been in place for at least one year and who have not had recent periodontal treatment.
IstanbulAges 18 years+ - NCT07173491Recruiting
Music therapy for anxious dental patients having cavity treatment
This trial tests whether listening to music during a single dental visit can reduce anxiety for people with mild to moderate tooth decay who are nervous about dental procedures.
Erzurum, ErzurumAges 18–40
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.