Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT07174752Recruiting
Gum graft comparison: non-submerged vs. standard technique
This trial compares two ways to do a gum graft to increase the width of attached gum in the lower front teeth area. It tests a newer method where the graft is not covered versus the traditional covered method.
GizaAges 18 years+ - NCT06972797Enrolling by invitation
Comparing Computer Methods for Measuring Upper Canine Teeth
This study compares two computer methods for measuring an upper canine tooth that has not come in properly. It uses a 3D scanning tool to see which method gives more accurate results and could help dentists plan better treatments.
Cairo, Cairo GovernorateAges 8–70 - NCT07276191Recruiting
Mobile app for teen oral health
This study tests a mobile app designed to help Portuguese teenagers improve their oral health. You would use the app at least twice in the first month to see if it makes a difference.
Lisbon, Lisbon DistrictAges 15–19 - NCT06900933Recruiting
Bone graft for upper jaw using jawbone blocks
This trial tests using a small piece of bone from your lower jaw to rebuild a narrow upper jaw so it can hold a dental implant. It compares using the bone alone versus covering it with a collagen membrane to see which works better.
CairoAges 20–40 - NCT07331207Recruiting
3D-printed expander for narrow upper jaw in young adults
This study tests a new 3D-printed expander that attaches to bone to widen a narrow upper jaw in young adults. It may help if you have a crossbite or need more room in your upper jaw.
Al MansurahAges 18–30 - NCT07364006Recruiting
Accuracy of metal-free guided implant surgery
This study tests a new way to place dental implants in people who need a full set of replacement teeth. It compares the accuracy of a method that uses a metal guide vs. one without it, to see if the simpler method works just as well.
Madrid, MadridAges 18 years+ - NCT07390188Recruiting
Oral lesions in Egyptian adults
This study will examine how common oral mucosal lesions (sores or changes inside the mouth) are among Egyptian adults. By joining, you help researchers understand which mouth conditions affect people like you.
CairoAges 18 years+ - NCT06514053Recruiting
Predicting success of molar pulp treatment
This study looks at whether certain signs in your tooth can help predict if a special type of filling (pulpotomy) will work for deep cavities in back teeth. It may help find the best treatment for you.
Hong KongAges Any age - NCT07578662Recruiting
Direct Pulp Capping for Deep Cavities in Back Teeth
This study tests a treatment where dentists cap (seal) an exposed tooth nerve in deep cavities of back teeth to see if it heals properly. This might help save your tooth instead of needing a root canal.
Rohtak, HaryanaAges 15–40 - NCT07262892Recruiting
3D study of jaw widening methods in children
This trial uses 3D imaging to compare two ways of widening the upper jaw in children. It may help your child if they need jaw expansion and haven't had it before.
Istanbul, FatihAges 6–12 - NCT07264491Recruiting
Testing ceramic crowns for front teeth
This study tests how well a new type of ceramic crown (one-piece, tooth-colored) works for teeth in the front of your mouth. It aims to see if these crowns are a good option for people who need a strong, natural-looking replacement.
Cairo, ManialAges 21 years+ - NCT05758454Recruiting
Prevent tooth decay and childhood weight gain by helping new parents
This study supports parents of babies (0–6 months) to change certain health habits with the goal of reducing future tooth decay and supporting healthy weight as children grow. You may be able to join if you recently had a newborn and you’re comfortable with the study procedures.
BergenAges 20–50 - NCT07261735Recruiting
Custom attachments for clear aligner therapy
This study tests whether custom-made attachment composites improve the effectiveness of clear aligners for treating mild-to-moderate crowding or spacing. It may help you achieve better tooth movement during orthodontic treatment.
AnkaraAges Any age - NCT07256691Recruiting
Bioceramic vs. resin sealer for root canal pain
This study tests two types of sealing materials used in root canals (a newer bioceramic one vs. a standard resin one) to see which causes less pain after treatment. If you have an infected, pain-free tooth that needs a root canal, this trial may help guide better care.
Lahore, Punjab ProvinceAges 18–55 - NCT07736222Recruiting
Does chewing affect artery stiffness in healthy adults?
This study looks at how your oral health and chewing habits might relate to your artery stiffness—a measure of heart health. Researchers will test participants' chewing ability and check their arteries using simple, non-invasive methods.
Innsbruck, TyrolAges 18 years+ - NCT07601347Recruiting
Immediate dental implants: two loading methods compared
This study compares two ways of placing and loading dental implants for damaged upper back teeth. Researchers will test whether a newer compression technique works as well as or better than the standard method for tooth replacement and bone healing.
Banī SuwayfAges 20–40 - NCT07737704RecruitingPhase 2/Phase 3
New bone graft for sinus lift before dental implants
This trial tests a new type of bone graft material for opening the upper-jaw sinus to make room for dental implants. It is for people with very little bone in the back of the upper jaw who need implants for missing teeth.
Ismailia, Ismailia GovernorateAges 18–65 - NCT06657651Enrolling by invitation
Immediate Implant with Different Membranes for Lower Back Teeth
This study tests placing a dental implant and a special membrane right after removing a damaged lower back tooth. It looks at how well different types of membranes help the bone heal around the implant.
Al MansurahAges 18–60 - NCT06732167Recruiting
Lyoplant for bone regrowth in dental implant surgery
This trial tests a special membrane called Lyoplant® that helps your jawbone grow back around a new dental implant. If you need a dental implant and your jawbone has a small gap or defect, this study might be a good fit for you.
Barcelona, CataloniaAges 18 years+ - NCT07240233Enrolling by invitation
Music for dental anxiety in adults
This trial tests whether listening to music through headphones during dental treatment can help lower anxiety. If you get nervous at the dentist and are willing to wear headphones, this study may be a good fit.
AlmadaAges 18 years+ - NCT07349095Recruiting
AI-assisted color test for gum redness around dental implants
This trial uses an AI tool to check for redness (erythema) in the gum tissue around dental implants. It aims to make diagnosis faster and more accurate during regular check-ups.
ShanghaiAges 18 years+ - NCT07036237Enrolling by invitation
Comparing pain relief rinses after root canal
This trial tests whether rinsing the tooth with either tramadol (a pain reliever) or dexamethasone (a steroid) after a root canal reduces pain better. It is for people with a single-rooted tooth that has a very painful, inflamed nerve.
Karachi, SindhAges 18–50 - NCT06525844Recruiting
Regenerative therapy for tooth nerve damage
This study tests a new way to help a damaged tooth nerve heal itself, instead of using a traditional root canal. It might be a good option if you have a front tooth or premolar with a dying nerve and a small opening at the root tip.
Islamabad, ICTAges 18–35 - NCT06526351Recruiting
Early implant with immediate vs. conventional loading
This trial compares two ways of placing a dental implant after a tooth is removed in the front upper jaw. One group gets the new tooth placed right away (immediate loading), and the other group waits a few months. The goal is to see which approach works better for healing and long-term success.
BelgradeAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.