Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT07264127Recruiting
I-arch system for early orthodontic treatment
This study tests a new orthodontic tool, the I-arch system, for straightening the lower front teeth when they are moderately crowded. It aims to see how well the I-arch works during the first stage of braces treatment.
KarbalaAges 12 years+ - NCT07003958Recruiting
Dental sealant study for young children
This study tests different cleaning agents used before applying tooth sealants on baby molars to see which works best. It may help children without cavities keep their teeth healthy.
Tokat ProvinceAges 4–6 - NCT06947070Recruiting
Dental implant temporary crown study
This trial tests how well 3D-printed temporary crowns for dental implants hold their color and surface smoothness. It may help you if you need a temporary crown while waiting for your permanent one.
Rohtak, HaryanaAges 20–60 - NCT07743684Recruiting
Jaw joint wash and meloxicam injection for jaw joint problems
This trial tests a treatment for people with jaw joint pain or clicking. It combines a jaw joint wash (arthrocentesis) with an injection of an anti-inflammatory medicine (meloxicam) to see if it helps relieve symptoms. This may be an option if other treatments like mouth splints haven't worked.
BaghdadAges 18 years+ - NCT07001826Recruiting
Custom plates to fix uneven jaw in facial asymmetry
This trial tests whether custom-made surgical plates can more accurately correct a tilted upper jaw (maxillary cant) in people with facial asymmetry. It aims to improve surgical precision and outcomes.
CairoAges 18 years+ - NCT07746206RecruitingEarly Phase 1
Insulin vs hyaluronic acid gel for advanced gum disease
This study compares two treatments applied directly to the gums to see which one better helps severe gum disease (periodontitis) heal. If you have advanced gum disease and haven't had treatment recently, you may be able to join.
CairoAges Any age - NCT07744776Recruiting
Dental implant design and stability for lower molar replacements
This study tests two different designs and surface treatments of dental implants to see which one is easier to place (insertion torque) and which becomes stable faster (implant stability quotient, a measure of how well the implant holds in the bone). If you need a dental implant in a lower molar and have healthy gums, you may be able to join.
VilniusAges 18 years+ - NCT06995859Enrolling by invitation
Dental filling teaching survey for pediatric dentists
This trial asks pediatric dentistry teachers in Egypt about how they teach amalgam fillings. It is a survey study to learn about current teaching practices.
CairoAges 20 years+ - NCT06871735Recruiting
Collagen Material to Help Gum Heal After Bone Graft for Implants
This study tests a special collagen material used during bone graft surgery to help the gum close over the graft. It might help people who need extra bone before getting a dental implant.
Columbus, OhioAges 21–75 - NCT06881095Enrolling by invitation
Dental Implants with or without Socket Shield for Front Teeth
This study tests two ways to place dental implants in the front of the mouth: one using a standard technique and one that leaves a small piece of your natural tooth (the socket shield) to help preserve the gum and bone. The goal is to see which method leads to better healing and a more natural-looking result.
TantaAges 18–55 - NCT07056959Recruiting
Collagen matrix for gum health around implants
This trial tests whether a collagen matrix can help improve the gum tissue around dental implants that have thin or insufficient gum width. It may help patients with narrow gum bands around their implants.
DubaiAges 21 years+ - NCT06960460Recruiting
ZygoFix dental implant study for people with severe bone loss
This study tests a new type of zygomatic (cheekbone) dental implant for people who have lost many teeth and have severe bone loss in the upper jaw. The goal is to see how well the implant works and if it stays safe over time.
Toulouse, FranceAges 18 years+ - NCT07436091Enrolling by invitation
Using pig skin to improve gum thickness around dental implants
This study tests a material made from pig skin (porcine dermis) to see if it can help make the gum tissue thicker and healthier around dental implants. It may be a good option for people who already have an implant in a back tooth area and need more gum tissue.
PortoAges 18 years+ - NCT07265726Enrolling by invitation
Oral health education for older adults: a study on intentionality
This trial tests a program to help older adults improve their oral health through education and intentional practice. It may help you learn to take better care of your teeth and gums.
New Taipei City, New Taipei CityAges 40–100 - NCT06943846Recruiting
Platelet gel for healing after tooth removal in older adults
This study tests if a gel made from your own blood can help your gums heal faster after a back tooth is removed. It is for patients getting dental care at the University of Nebraska Medical Center.
Lincoln, NebraskaAges 14–80 - NCT06943443Enrolling by invitation
Vitamin D and expander treatment for teens
This trial looks at whether vitamin D levels affect how well a special expander (MARPE) works to fix a narrow upper jaw in teens. If you are 15–18 and have a narrow upper jaw, you may be able to join.
Konya, MeramAges 16–18 - NCT06352645Recruiting
Testing a compact water flosser for gum health
This trial tests a new water flosser (Bixdo Ultra Compact) to see if it safely improves gum health in people with moderate to severe gum disease. You would use the flosser at home and attend check-ups for about 4 weeks.
Boston, MassachusettsAges 18–70 - NCT06939582RecruitingPhase 1/Phase 2
Hydroxychloroquine for radiation mouth sores
This trial tests if hydroxychloroquine tablets can prevent or reduce mouth sores caused by radiation therapy for head and neck cancer. If you are about to start radiation for head and neck cancer and have not had radiation before, this study might help manage painful mouth sores.
Chengdu, SichuanAges 18–80 - NCT07250022Recruiting
Checking for hidden decay after tooth fillings in children
This study tests a gentle way to fill cavities in baby teeth (called Atraumatic Restorative Treatment, or ART) to see if some decay is left behind. It may be a good option for children with cavities who are nervous about traditional dental drills.
Çanakkale, KepezAges 4–9 - NCT06884813Recruiting
Color-changing fillings after teeth whitening
This study tests a new type of tooth-colored filling that can adjust its color after professional whitening. It may help people who already have certain white fillings on their front teeth and want to see if the new filling blends better after whitening.
IrbidAges 18 years+ - NCT07317596Enrolling by invitationPhase 3
Comparing two treatments to reduce pain after wisdom tooth surgery
This trial compares two treatments, methylprednisolone and hyaluronic acid, given during wisdom tooth removal to see which one helps reduce pain and swelling afterward. You may participate if you need a special type of impacted wisdom tooth removed and are generally healthy.
SanaaAges 18–40 - NCT07310979Enrolling by invitation
Study of a special dental implant design
This trial tests a new shape for a dental implant that holds three teeth. It may help people who need a strong, stable replacement for missing teeth.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT06918639Recruiting
Pulpotomy for painful adult teeth with deep cavities
This study tests a treatment called pulpotomy for adults with a deep cavity in a tooth that is causing pain. If you have a tooth that hurts but is still healthy enough to save, this treatment might help relieve the pain and keep the tooth.
Alcorcón, MadridAges 18 years+ - NCT07604155Enrolling by invitation
Bone grafting for sinus lift in dental implants
This trial tests two ways to add bone in your upper jaw so dental implants can be placed. Researchers compare custom-made bone blocks to bone particles to see which works better for your bone growth.
TantaAges 20 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.