Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT07108465RecruitingEarly Phase 1
Anesthetic comparison for wisdom tooth removal
This trial compares two numbing medicines, bupivacaine and ropivacaine, to see which works better for removing impacted lower wisdom teeth during general anesthesia. It may help determine which option provides better pain relief after surgery.
Porto Alegre, Rio Grande do SulAges 18–60 - NCT07099846Recruiting
Hyaluronic acid and polynucleotides for tooth socket preservation
This trial tests a gel made of hyaluronic acid and polynucleotides to help preserve the bone and gum after a tooth is pulled. It may help you keep a healthy foundation for a future dental implant.
ParmaAges 25 years+ - NCT07095946Recruiting
Comparing two numbing methods for kids' dental work
This trial tests if a special numbing injection into the ligament around a tooth works as well as the standard numbing shot for children having dental treatment. It uses an electronic syringe to make the injection more comfortable.
Latakia, Latakia GovernorateAges 6–10 - NCT07088172Recruiting
Gum graft timing for dental implants in the lower back jaw
This trial compares two different times to do a gum graft around a dental implant in the lower back jaw. It aims to find out which timing works better for patients who don't have enough thick gum tissue (less than 2 mm).
Hangzhou, ZhejiangAges 18 years+ - NCT06569264Recruiting
Comparing socket preservation methods after tooth extraction
This trial tests two different treatments to preserve the bone and gum after a tooth is removed. It compares using a dentin graft with I-PRF (a special blood concentrate) to the same treatment with added vitamin C. The goal is to see which helps the healing better before a dental implant.
CairoAges 18–65 - NCT07077915Enrolling by invitation
New drilling method vs. standard for immediate dental implants
This trial tests a new drilling method called osseodensification (which makes the bone denser) versus the standard way of drilling for placing a dental implant right after pulling a tooth. It is for people who need a lower back molar removed and want an implant placed immediately.
BeirutAges 25–45 - NCT07608289Recruiting
Preserving Bone After Tooth Extraction Using Your Own Tooth
This study tests whether using natural material from your own tooth can help preserve jawbone after a tooth is removed. Keeping bone healthy after extraction may make future tooth replacement easier and more successful.
OstravaAges 18–70 - NCT07073196Recruiting
Narrow vs standard implants for single missing molar
This study compares two types of dental implants (narrow and standard width) for replacing a single missing back tooth (molar). The goal is to see how well narrow implants work in areas where the jawbone is not very wide, offering a less invasive option for eligible patients.
DubaiAges 18 years+ - NCT07459075RecruitingPhase 4
Bone graft with hormone for sinus lift before dental implants
This trial tests if adding parathyroid hormone to a bone graft improves bone growth in the upper jaw before placing dental implants. It may help people who have lost teeth and have very little bone in the sinus area.
BaghdadAges 18 years+ - NCT07610876Recruiting
Dentin Graft With Melatonin for Tooth Implant Success
This study tests whether a special graft made from your own tooth material, with or without melatonin (an antioxidant), helps new dental implants integrate better into bone after tooth extraction. The goal is to improve how well implants take hold and function.
IsmailiaAges 20 years+ - NCT07056920Recruiting
Bone growth for lower jaw implants using a custom shell
This study tests whether a custom-made porous zirconia shell can help grow new bone in a narrow lower jaw so a dental implant can be placed. It might be a good option if you have a missing back tooth and need more jawbone for an implant.
Giza, Giza GovernorateAges 18 years+ - NCT07048171Recruiting
Bone graft and blood concentrate for tooth infection healing
This trial tests whether using a bone graft (allograft) together with your own blood concentrate (iPRF) and a collagen membrane helps heal the bone and gum around a tooth with a long-standing infection. It might be a good option if you have a tooth that keeps getting infected despite a root canal and has a deep pocket on the cheek side.
Rohtak, HaryanaAges 18 years+ - NCT06579768Recruiting
Using CT scans to predict jaw cyst type before surgery
This study tests if analyzing CT scans with artificial intelligence can help doctors tell the difference between types of jaw cysts before surgery. This could help avoid surgery or choose the best treatment for you.
Guangzhou, GuangdongAges Any age - NCT05816525Recruiting
Study tooth symptoms and cavity depth after partial removal
This study looks at how tooth symptoms and the depth of a cavity affect outcomes when dentists remove only part of the decayed tissue. You might benefit by getting care guided by careful tooth testing and dental imaging, while contributing to better treatment decisions for deep cavities.
EspooAges 18–50 - NCT06581614Recruiting
Chewing ability after single implant for missing second molar
This trial checks how well you can chew after getting a single implant to replace a missing second molar tooth. It compares chewing function before and after treatment to see how the implant helps.
TaipeiAges 25–85 - NCT07029880Recruiting
Comparing two types of porcelain for metal-ceramic dental bridges
This study compares two different porcelain materials used to make metal-ceramic dental bridges, to see which works better. It may help you get a stronger, longer-lasting bridge.
CairoAges 21–80 - NCT07027709Recruiting
Hybrid ceramic veneers for better smiles
This trial tests how well hybrid ceramic laminate veneers work for fixing front teeth. It may help if you need cosmetic improvement and your teeth are healthy enough.
CairoAges 21 years+ - NCT05639907Recruiting
Miniscrew study comparing two surface coatings
This study tests whether orthodontic miniscrews with one special coating cause less gum tissue inflammation and stay stable better than miniscrews treated with ethanol. It may help improve how well miniscrews work and how healthy the tissue around them stays over follow-up visits.
Aurora, ColoradoAges 12 years+ - NCT07019428Recruiting
A new way to stabilize gum grafts with titanium tacs
This trial tests a method using small titanium tacs to hold a gum graft in place instead of stitches. It may help people with thin gum tissue around dental implants have a more comfortable and effective procedure.
CairoAges 18–40 - NCT06725134Recruiting
Do therapy dogs help kids feel calmer during dental shots?
This study tests if having a trained therapy dog in the room reduces a child's anxiety and improves their behavior when getting numbing medicine for dental work. It could help children who are nervous about dental procedures feel more at ease.
Ann Arbor, MichiganAges 4–12 - NCT06588998RecruitingPhase 2
Gum graft vs. special membrane for implant gum recession
This study tests whether a special membrane made from animal tissue (xenogenic cortical membrane) works as well as a gum graft (connective tissue graft) to fix gum recession around dental implants. If you have thin gums and an implant with receding gum, this trial may help cover the exposed implant surface.
Tanta, Gharbia GovernorateAges 20–50 - NCT07747350Recruiting
Laser vs pain pills for braces pain in Malay women
This study compares a low-level laser treatment with standard painkillers to see which works better for reducing pain from getting braces. It is for Malay women aged 18-33 who have never had braces and are generally healthy.
Kota Bharu, KOTA BHARUAges 18–33 - NCT06759896Recruiting
Facemask vs braces for underbite in growing children
This trial compares a facemask device with upper braces to correct underbite in children ages 7–10. It aims to find which treatment works better to align the jaw and teeth.
Kuala Lumpur, Kuala LumpurAges 7–10 - NCT06441032Enrolling by invitation
Metal crown survival study
This study looks back at patient records to see how long single-tooth crowns and partial crowns made of precious metal or non-precious metal last. It aims to find out which type of metal may hold up better over time.
Göttingen, Lower SaxonyAges Any age
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.