Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT06623851Recruiting
Digital vs. traditional dental molds for preschoolers
This study compares two ways of taking dental molds (digital vs. traditional) to see which one makes children feel less anxious and more comfortable. It is for young children who are cooperative and have never been to the dentist before.
AlexandriaAges 4–6 - NCT06622759RecruitingPhase 2
Using a collagen membrane to preserve gum bone after dental implant
This trial tests whether a special collagen material placed around a new dental implant can help prevent bone loss in the upper front gum area. It is for people needing a single implant in a specific tooth zone and may help keep the bone strong for a better cosmetic result.
Thessaloniki, ThessalonikiAges 18–75 - NCT07441148Recruiting
Digital vs. parent-led toothbrushing for kids
This study compares two ways of teaching children how to brush: with a digital tool or by having a parent show them. It looks at how well they brush and how their teeth look after brushing.
Los Angeles, CaliforniaAges 3–6 - NCT07653802Recruiting
Laser vs. surgery for crown lengthening
This study compares a new laser method for crown lengthening to the traditional surgical approach. Crown lengthening reshapes gum and bone to expose more tooth, often needed before placing a crown or for cosmetic reasons. The laser may be less invasive and allow faster healing.
Ajman, Ajman EmirateAges 20–70 - NCT06613932Recruiting
Saving a painful molar with protein gel and minerals
This study tests whether a special protein-rich gel (L-PRF) combined with a tooth-repairing mineral (nanohydroxyapatite) can help save a painful back molar tooth by treating the nerve inside, instead of removing it. The goal is to see if this treatment stops pain and keeps the tooth healthy.
Cairo, New CairoAges 15–30 - NCT06809829Recruiting
Doxycycline gel sponge for front tooth implants
This trial tests whether a special sponge containing doxycycline (a type of antibiotic) placed around a new implant in the front of the mouth helps it heal better. It's for people who need a single tooth replaced in the upper front area.
Kafrelsheikh, KafrelsheikhAges 18–50 - NCT06898918Enrolling by invitation
Mothers' feeding habits and kids' eating and tooth health
This study looks at how mothers control their child's eating, how the child eats, and whether it relates to early childhood cavities. It may help families understand what affects their preschooler's dental health.
CairoAges 3–5 - NCT06599814Recruiting
Pulp capping for cavities in permanent molars
This study tests two methods for treating a tooth where the soft inner part (pulp) has been exposed by a cavity. It aims to see which approach works better to save the tooth and avoid a root canal.
Kafr ash Shaykh, Kafr El-ShaikhAges 19–40 - NCT06593925Recruiting
Snap-on denture made from a strong plastic for older adults
This trial tests a new plastic material (polyoxymethylene) to make a telescopic denture—a partial denture that snaps onto your remaining teeth. It is for people aged 65 and older who have lost several teeth but still have some healthy teeth to support the denture.
BelgradeAges 65–100 - NCT06594328Enrolling by invitation
Text messages to keep gums healthy during pregnancy
This trial tests if simple text messages can help pregnant women keep their gums healthier. If you are in your 2nd trimester and have gingivitis (bleeding gums), you may be able to join and get supportive texts during pregnancy.
Lahore, Punjab ProvinceAges 18 years+ - NCT07730359Recruiting
Testing a treatment for white spots after braces
This trial tests a new gel called Epinamel to reverse white spots that form on teeth after braces are removed. If you recently had braces taken off and have white marks on your teeth, this study might help improve them.
LondonAges 12–60 - NCT06335628Recruiting
Building gum tissue for a missing tooth: graft comparison
This study tests two ways to build up gum tissue where a tooth is missing before placing an implant or bridge. It compares using a small piece of your own gum (connective tissue graft) versus a man-made collagen material to see which gives better volume and shape.
BernAges 18 years+ - NCT05986669Recruiting
DSP dental implant safety study for tooth loss
This trial tests several types of DSP dental implants to see if they are safe and work well for people with missing teeth. It is for patients who have had tooth loss for at least three months and are in good overall health.
Campo Largo, ParanáAges 18–70 - NCT06541236Recruiting
Preserving jawbone after tooth removal using your own tooth
This trial tests a way to preserve the shape and volume of your jawbone after a tooth is pulled. Instead of using artificial materials, the dentist grinds your extracted tooth into a natural bone-graft material and places it back into the socket. The goal is to keep the bone strong and healthy for a future dental implant or bridge.
MoscowAges 18–65 - NCT07683962Recruiting
Early healing and gum surgery outcomes
This trial tests whether early wound healing affects the results of regenerative gum surgery, which aims to rebuild bone around teeth affected by advanced gum disease.
Rome, RomeAges 18 years+ - NCT06519773RecruitingPhase 1/Phase 2
Modified bone-saving implant technique for front teeth
This study tests a new surgical technique for placing a dental implant in a front tooth area where the bone on the lip side is very thin. The technique aims to preserve the bone and gum tissue to get a better cosmetic result.
TantaAges 18–60 - NCT06502886Recruiting
Stability after braces with premolar removal and special retainers
This study tests whether using a special type of retainer (bonded on the tongue side and the roof of the mouth) helps keep teeth stable after braces for people who had their upper and lower first premolars removed. If you're finishing orthodontic treatment and need a retainer, this study may apply to you.
CairoAges 18 years+ - NCT06507709Recruiting
Sinus lift study using a special bone graft putty
This study tests a new type of bone graft putty for people who need a sinus lift before getting dental implants. It may be an option if you have some existing bone and are generally healthy or have well-controlled diabetes.
San Antonio, TexasAges 18–85 - NCT06957509Recruiting
Saliva test to predict cavities in 3-year-olds
This study looks at proteins in the spit of 3-year-old children to see if they can help doctors better predict which kids might get cavities. The goal is to improve how we assess cavity risk at a young age.
StockholmAges 3–3 - NCT06504888Recruiting
Does penicillin allergy affect sinus lift success?
This study looks at whether people with a penicillin allergy have a higher risk of sinus lift failure. It checks how well the sinus lift and any dental implants heal.
Sant Cugat del Vallès, BarcelonaAges 18 years+ - NCT06724107Recruiting
UVC light treatment for dental implants
This trial tests if a special UVC light treatment on dental implants helps them heal better. It may be an option if you need a dental implant with or without bone or gum surgery.
MadridAges 18–65 - NCT06586892Recruiting
MRI study to predict jaw injury after radiation therapy
This study uses special MRI scans before and after radiation therapy to see if they can predict damage to your jawbone. If you are getting radiation to the head or neck area, this study may help monitor side effects.
Houston, TexasAges 18 years+ - NCT06488599Enrolling by invitation
Bone loss around lower jaw implant dentures and bridges
This study looks at bone loss around implants in the lower jaw for two types of tooth replacements: a denture held by 2 implants or a fixed bridge on 4 implants. The goal is to see how much bone is lost around the implants after 5 years.
BeirutAges Any age - NCT02818400Recruiting
Face transplant evaluation for severe facial tissue loss
This trial studies face tissue transplantation for people who have lost facial tissue that cannot be fixed with standard surgical methods. It focuses on how the face looks and works after surgery, and it may help restore function and appearance when other options aren’t enough.
AmiensAges 18–50
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.