Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,544
- Phase 2144
- Phase 384
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Head and Neck Cancer35
- Gingivitis34
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT07550725Recruiting
Full Arch Dental Implant Impressions Study
This study tests different techniques for taking accurate impressions (molds) of your upper jaw when preparing for full-arch dental implants (a fixed bridge supported by implants). The goal is to improve the fit and success of your final implant-supported teeth.
GizaAges 55–65 - NCT07544394Recruiting
Understanding Fatigue in Sjögren's Syndrome
This study explores why people with Sjögren's syndrome experience fatigue and what factors predict it. Researchers will follow you for 3 months to better understand your fatigue patterns and potentially improve treatment.
KahramanmaraşAges 18 years+ - NCT07547202Recruiting
Gum Disease Treatment Effects on Saliva in Smokers and Non-Smokers
This study tests whether a non-surgical cleaning procedure for gum disease changes markers in your saliva differently depending on whether you smoke. Researchers want to understand how smoking affects how your mouth heals.
Baghdad, Baghdad GovernorateAges 18 years+ - NCT07547371Recruiting
Aromatherapy and Digital Anesthesia for Dental Anxiety in Children
This study tests whether aromatherapy (calming scents) and digital anesthesia (numbing technology) can help reduce anxiety and pain when children need a baby molar removed. The goal is to find gentler ways to keep children comfortable during dental procedures.
Istanbul, IstanbulAges 6–12 - NCT07547904Recruiting
Bioactive filling material for back tooth cavities
This trial tests a newer type of tooth-filling material (bioactive bulk-fill) in back teeth that need repair. Researchers will compare how well it works compared to standard fillings, which may help improve how long fillings last.
IstanbulAges 18–50 - NCT07548268Recruiting
Ultrasound imaging for suspected throat cancer
This study tests a new ultrasound method to help doctors identify throat cancer earlier. You would undergo imaging scans to see if ultrasound can better detect cancer in the back of the throat.
AarhusAges 18 years+ - NCT07551115Recruiting
Oral Parasites and Gum Health Study
This study examines whether certain microscopic parasites in the mouth are linked to gum disease. Researchers will compare people with healthy gums to those with gum inflammation or disease to understand this connection better.
Bolu, GölköyAges 18 years+ - NCT07551024Recruiting
Zygomatic Implant Placement Accuracy: Metallic vs Resin Guides
This study compares two types of surgical guides (metallic and resin-based) to help dentists place zygomatic implants—special dental anchors used when the upper jaw bone is severely worn down. The goal is to see which guide method places these implants more accurately.
New Cairo, Cairo GovernorateAges 18 years+ - NCT07549347Recruiting
Smart Toothbrush vs. Professional Cleaning for Gum Disease
This study tests whether using an intelligent (electric) toothbrush with a smartphone app can manage early gum inflammation as effectively as professional dental cleaning. If you have mild gum disease, this trial may help you avoid or delay professional treatments.
Shanghai, Shanghai MunicipalityAges 18–64 - NCT06737289Recruiting
Surgical guide effectiveness study
This trial tests whether using surgical guides in dental implant surgery leads to better outcomes. It may help if you are between 18 and 80 and are planning to get dental implants.
MadridAges Any age - NCT06745141Recruiting
Gum disease treatment after a heart attack
This trial tests whether treating severe gum disease can improve recovery after a heart attack (STEMI). If you recently had a heart attack and also have serious gum problems, you may be able to join and receive periodontal care.
Shanghai, Shanghai MunicipalityAges 30 years+ - NCT06734325Recruiting
Mobile health program for braces patients
This study uses text messages on WhatsApp to help young people with braces improve their brushing habits. It will test whether a simple mobile program can keep your teeth cleaner and help you learn more about oral health.
AlexandriaAges 16–25 - NCT02891967Recruiting
Compare two tooth-filling methods for back teeth
This trial tests whether a newer “bulk-fill” way of placing tooth filling works as well as the usual step-by-step method for restoring back teeth with cavities. It aims to see which approach best meets dental quality standards over one year.
Cairo, Cairo GovernorateAges 18–38 - NCT04934176Recruiting
3D study of smile reconstruction for facial paralysis
This study looks at how well “smile reconstruction” surgery works for people with facial paralysis, using 3D measurements that reflect patient experience and movement. You may be able to help test which nerve-connection approach leads to better smile outcomes.
Columbus, OhioAges 18–75 - NCT07536204Recruiting
Gum Inflammation Study: Understanding Immune Cell Activation
This research study investigates how certain immune proteins (JAK1 and JAK2) work in gum tissue, both in healthy gums and in gum disease. Understanding this may help develop better treatments for periodontal disease in the future.
Santiago, Metropolitan RegionAges 18 years+ - NCT07534423Recruiting
Finishing teeth after braces removal training
This study teaches dental professionals best practices for completing and polishing teeth immediately after braces are removed. It's designed for orthodontists and dentists who work with braces to improve their finishing techniques.
Roma, RMAges Any age - NCT07535060Recruiting
Growing bone at tooth gap sites with or without bridge
This study tests whether bone can be developed at the site of a missing tooth in your smile zone, with or without a temporary tooth bridge. The goal is to improve the site for a future implant or bridge.
CairoAges 18 years+ - NCT07536399RecruitingPhase 3
Bone Marrow Treatment for Jaw Joint Pain Relief
This study tests whether injecting your own bone marrow cells into your jaw joint during a minimally invasive procedure can reduce pain and improve jaw function better than arthroscopy alone. It's for people with significant jaw pain that hasn't improved with conservative treatments like NSAIDs, physical therapy, and bite splints.
New York, New YorkAges 18–75 - NCT07537426Recruiting
Acupuncture for Dry Eyes After Facial Paralysis
This trial tests whether tiny acupuncture needles placed under the skin can help relieve dry eyes and other eye discomfort that develops after long-lasting facial paralysis. The goal is to see if this treatment can improve symptoms when standard care hasn't worked well enough.
Hangzhou, ZhejiangAges 18–65 - NCT07535177Recruiting
Gas6 and MerTK Protein Markers in Gum Disease
This study measures two proteins (Gas6 and MerTK) in the blood and gum tissue of people with and without gum disease to better understand how these proteins relate to periodontal health. Results may help doctors identify new ways to diagnose or treat gum disease in the future.
Bolu, BoluAges 18 years+ - NCT04848870Recruiting
Check dental and gum health in Sjögren’s disease
This study looks at dental and gum (periodontal) health in adults with Sjögren’s syndrome. It may help researchers understand how Sjögren’s affects the mouth and how patients can be supported better.
Ivry-sur-Seine, Île-de-France RegionAges 18 years+ - NCT06751979Recruiting
Probiotics for people with braces
This trial tests if a probiotic can improve oral health for people with braces. It might help reduce plaque buildup around brackets and wires.
AarhusAges 10 years+ - NCT07533110RecruitingPhase 4
NOVAMag Shield for tooth extraction and implant placement
This study tests a new bone-grafting material (NOVAMag® SHIELD) used during tooth extraction and immediate dental implant placement in visible areas of the mouth. The goal is to help the bone heal better around your new implant.
Almada, Setúbal DistrictAges Any age - NCT07532200Recruiting
Pain genes and inflammation in tooth root canal treatment
This research study examines how your genes affect pain and inflammation when you have a painful tooth that needs root canal treatment. By studying these responses, researchers hope to better understand why some people experience different levels of pain during dental procedures.
New Delhi, National Capital Territory of DelhiAges 18–50
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,741 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.