Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,544
- Phase 2144
- Phase 384
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Head and Neck Cancer35
- Gingivitis34
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT07527351Recruiting
Testing a laser imaging tool for gum health assessment
This study tests a new laser imaging technology that measures blood flow in gum tissue to see if it's accurate and reliable. Researchers want to understand if this tool could help dentists better assess gum health and healing after surgery.
Madrid, MadridAges 18 years+ - NCT07533110RecruitingPhase 4
NOVAMag Shield for tooth extraction and implant placement
This study tests a new bone-grafting material (NOVAMag® SHIELD) used during tooth extraction and immediate dental implant placement in visible areas of the mouth. The goal is to help the bone heal better around your new implant.
Almada, Setúbal DistrictAges Any age - NCT07532200Recruiting
Pain genes and inflammation in tooth root canal treatment
This research study examines how your genes affect pain and inflammation when you have a painful tooth that needs root canal treatment. By studying these responses, researchers hope to better understand why some people experience different levels of pain during dental procedures.
New Delhi, National Capital Territory of DelhiAges 18–50 - NCT07531875Recruiting
Probiotics to Help Treat Advanced Gum Disease
This trial tests whether taking probiotics (beneficial bacteria) alongside standard gum disease treatment can help reduce deep pockets in your gums and improve healing. You'd be asked to take probiotics as an add-on to the care you're already receiving.
Kuala Lumpur, Kuala LumpurAges 18 years+ - NCT07526350RecruitingEarly Phase 1
MTS109 for Hard-to-Treat Autoimmune Diseases
This early-stage trial tests a new treatment called MTS109 for autoimmune diseases (like lupus, muscle inflammation, scleroderma, vasculitis, or Sjögren's syndrome) that haven't responded well to standard medications. The goal is to see if MTS109 can help control disease that keeps flaring or getting worse despite current treatments.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07529444Recruiting
Cleaning methods for infected dental implants
This study compares different cleaning methods for dental implants that have an infection around them (peri-implantitis). It aims to find the best way to clean the implant surface to help it heal and be preserved.
ZagrebAges Any age - NCT07526259Recruiting
Novel gum recession surgery compared to standard technique
This study compares two surgical approaches to treat multiple areas of receded gums (where gum tissue has pulled back from teeth). Both techniques use grafted tissue to restore gum coverage and protect tooth roots.
Cairo, AlManialAges 18 years+ - NCT07533240Recruiting
Tooth Wear Treatment Effects on Bite and Jaw
This study looks at how a specific tooth-restoration treatment (called the One-Step No-Prep protocol) affects your bite alignment and jaw joint over time. Researchers want to understand if this treatment helps improve how your teeth fit together.
LiègeAges 18 years+ - NCT07526129Recruiting
Ridge Preservation After Back Tooth Extraction
This study looks at whether a procedure called ridge preservation, done after removing upper back teeth, helps prevent the need for sinus bone grafting later. Researchers will compare patients who had this procedure with those who didn't, using 10 years of X-ray records.
Beirut, BeirutAges 18 years+ - NCT07526272Recruiting
Magnesium membrane versus bone graft for tooth implants
This study compares two methods to rebuild bone around immediate tooth implants (implants placed right after tooth extraction). The goal is to see which material—a magnesium membrane or bone graft—works better to support the implant and maintain bone structure.
GizaAges Any age - NCT07526337Recruiting
Digital Planning for Sinus Lift Dental Implants
This study examines how computer planning improves dental implant surgery when bone needs to be built up in the upper back jaw. Researchers will assess whether digital planning helps predict better outcomes for patients getting sinus lift procedures.
Beirut, BeirutAges 18 years+ - NCT07532161Recruiting
Fibrin and Laser Treatment for Gummy Smile Surgery
This study compares two treatment approaches—liquid fibrin (a clotting substance) and soft laser therapy—to help healing and prevent relapse after surgery to reduce a gummy smile caused by an overactive upper lip. The goal is to find which method works better for long-term results.
Damascus, Rif-dimashq GovernorateAges 18–50 - NCT06642324Recruiting
HPV and genetics in head and neck cancer study
This study looks at how HPV infection and genetic changes relate to head and neck squamous cell carcinoma. If you have this type of cancer, joining could help doctors learn more about the disease and improve future treatments.
Dhaka, Dhaka DivisionAges 18 years+ - NCT05610878RecruitingPhase 1
Stem cell help to improve fat grafting results
This early-phase study tests whether “preconditioned” stem cells from fat tissue can improve the look of fat transferred during liposuction and grafting. If you qualify, you may receive stem cells along with fat grafting to see how well it works and how safe it is.
Lahore, Punjab ProvinceAges 18–50 - NCT06684275Recruiting
Radiofrequency treatment comparison for trigeminal neuralgia pain
This trial compares two types of radiofrequency treatment (pulsed and thermal) to see which works better for people with trigeminal neuralgia, a condition that causes severe, stabbing facial pain. If you have had facial pain for at least six months that isn't controlled by medicine, this study may help you find relief.
Zagazig, Sharqia ProvinceAges 18–60 - NCT07518615Recruiting
Safety and Effectiveness of Guided Dental Implant Surgery System
This trial tests a new computer-guided system (Straumann Dynamic Navigation Falcon) that helps dentists place dental implants more precisely. If you need one or more dental implants and have healthy gums and jaw, this study may help determine if this guided approach is safe and works well.
GhentAges 18 years+ - NCT07519382Enrolling by invitation
Comparing two types of tooth-covering restorations
This study compares two different ways to restore damaged teeth using computer-designed tooth coverings (onlays). You would receive one type of restoration and have it checked regularly to see how well it works and lasts.
Budapest, BudapestAges 18 years+ - NCT07521267Recruiting
Nano-coated screws for teeth straightening in teens
This trial tests special small screws coated with nano-material to help move upper front teeth back into place during braces treatment. The screws act as anchors to make tooth movement more effective for patients with protruding upper front teeth.
Cairo, Cairo GovernorateAges 14–20 - NCT07524569Recruiting
Digital vs. manual anesthesia in children's dental care
This study compares two ways of numbing teeth (digital intraosseous and manual intraligamentary anesthesia) in children who need fillings on back molars. It aims to see which method works better and causes less discomfort.
Izmir, CigliAges 6–12 - NCT07517172Recruiting
Brain Stimulation Patch for Jaw Pain: Home Treatment Study
This study tests whether a small, stick-on electrical patch placed on your ear can reduce temporomandibular disorder (TMD) jaw pain when used at home. You would apply the patch yourself and complete surveys about your pain to help researchers learn if this non-invasive approach is safe and feasible.
Minneapolis, MinnesotaAges 18–65 - NCT07517926Recruiting
Chewing gum and cold water gargle after lung breathing tube procedure
This study tests whether chewing gum and gargling with cold water can reduce sore throat and other discomfort after a bronchoscopy—a procedure where doctors look inside your airways with a thin camera. If it works, it could be a simple, safe way to feel better after the procedure.
AnkaraAges 18 years+ - NCT07523802Recruiting
Managing pain after gum graft surgery with two methods
This trial tests two different ways to protect and manage pain in the mouth after a gum graft surgery. You would compare a product called Ora-Aid with a custom acrylic stent (a protective cover) to see which helps with healing and reduces discomfort better.
CairoAges 18 years+ - NCT07523815RecruitingPhase 4
AI-Assisted versus Standard Planning for Dental Implants
This study compares using artificial intelligence computer planning versus standard planning methods for placing a single dental implant in your back teeth. The goal is to see if AI planning makes the implant placement faster, easier, and more precise.
Cairo, ManialAges 18–50 - NCT07518901Enrolling by invitationPhase 4
New Nanoparticle Treatment for Root Canal Therapy
This study tests a new type of nanoparticle (tiny medical particles) called Ferumoxytol to help treat infected tooth roots. Researchers want to see if this approach works better than standard root canal treatments.
Philadelphia, PennsylvaniaAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,741 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.