Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT06473922Recruiting
Fear and healing after wisdom tooth or jaw implant surgery
This study measures fear and anxiety levels and monitors wound healing in patients getting wisdom tooth extraction or jaw implants, comparing local anesthesia to general anesthesia.
Be’er Ya‘aqovAges 18–85 - NCT07462156Recruiting
AI Tool for Dental Students to Self-Assess Tooth Preparations
This trial tests a new AI-powered digital tool that helps dental students self-check their tooth preparations. If you are a third-year preclinical dental student who has completed the basic course but hasn't used digital assessment tools before, you may be able to join this study to see if the AI tool improves your skills.
El AlameinAges 18–20 - NCT07677007Recruiting
Sinus lift with bone graft materials for dental implants
This study compares two ways to build up bone in the upper jaw for dental implants. You may qualify if you need a sinus lift and have healthy gums and overall health.
Ajman, Ajman EmirateAges 21–70 - NCT06447311Recruiting
Hyaluronic acid gel for gum tissue rebuilding
This study tests whether a hyaluronic acid gel can help rebuild gum tissue between teeth. It may be an option if you have gum recession in your front teeth and are in good oral health.
Mahbūbnagar, TelanganaAges 18 years+ - NCT06455306Recruiting
Air polishing for gum inflammation around implants
This trial tests whether a special cleaning method called erythritol air polishing can treat gum inflammation around dental implants. If you have a dental implant with red or swollen gums, you may be able to join.
CoimbraAges 18–80 - NCT06965387Recruiting
Deep learning study for gummy smile analysis
This study uses artificial intelligence to analyze smiles and identify a gummy smile (excess gum showing when you smile). It may help researchers better understand and diagnose this condition.
Ankara, CankayaAges 12 years+ - NCT06354374Recruiting
Classifying jawbone shape for better dental implants
This study looks at how the shape and thickness of your gum and jawbone affect dental implant success. It uses a 3D scan (CBCT) to classify the bone, which may help doctors choose the best treatment for missing teeth.
Al Shorouk City, Cairo GovernorateAges 18 years+ - NCT06207617Recruiting
Immediate implant after molar removal: with or without bone graft
This study tests whether placing a dental implant right after removing a lower molar works better with or without adding a bone graft. It looks at how the bone and gum change over time.
CairoAges 18–50 - NCT07030088Recruiting
Testing a new two-sided toothbrush for healthier gums
This trial tests a special toothbrush that cleans both sides of your teeth at once. It compares this new brush to a regular one to see if it improves gum health in dentists.
RiyadhAges 25–40 - NCT06293521RecruitingPhase 2
Nerve treatment options for deep cavities in baby teeth
This study compares two ways to treat severe cavities in baby teeth: removing only the infected part of the nerve (pulpotomy) versus removing all the nerve tissue (pulpectomy). It looks at which method helps the tooth heal better and stay healthy longer.
CairoAges 4–6 - NCT06987253Recruiting
Test of OROXID® mouth rinse after oral surgery
This trial tests if a special mouth rinse, OROXID®, helps heal and prevent infection after a tooth extraction or root-tip surgery. It may be an option for people who are generally healthy and need this type of oral surgery.
Muljava, Municipality of Ivančna GoricaAges 18 years+ - NCT06275789Recruiting
Bone graft mix for preserving jawbone after tooth extraction
This study tests a mix of two bone graft materials (one from donated human bone and one from cow bone) to see if it helps preserve the jawbone after a tooth is pulled, so there is enough bone for a dental implant later. It may be a good option if you are generally healthy and need a molar or premolar removed.
Fort Lauderdale, FloridaAges 18 years+ - NCT07203456Recruiting
Teaching dental students about jaw pain
This trial tests different ways to teach dental students about temporomandibular disorders (jaw pain conditions). It aims to find the best teaching method so future dentists can better help patients with jaw pain.
Downers Grove, IllinoisAges 18 years+ - NCT06246656Recruiting
Maxillary expansion with a custom 3D-printed appliance
This trial tests a computer-designed device to widen the upper jaw. It may help people with a narrow upper jaw or a crossbite (when upper teeth sit inside lower teeth).
Vienna, State of ViennaAges 12–26 - NCT07234149Recruiting
Comparing tooth color change and removal time for two attachment materials
This study compares two types of tooth-colored materials used for the small bumps (attachments) placed on teeth during clear-aligner treatment. Researchers want to see which material causes less tooth staining and is easier for the dentist to remove.
Kirkuk, Kirkuk GovernorateAges 18–40 - NCT07198919Enrolling by invitationPhase 1/Phase 2
Pain relief during root canal for infected tooth: gel vs. antibiotic paste
This trial compares two medicines placed inside a tooth after root canal cleaning to see which reduces pain better between appointments. If you have an infected single-root tooth and are between 16-45 years old, you may be able to join.
Karachi, SindhAges 16–45 - NCT06141239Recruiting
3D imaging to study bone healing after tooth extraction
This trial uses advanced 3D imaging to measure how well your jawbone heals after a tooth is removed, specifically for people who plan to get a dental implant later. It aims to understand natural bone regrowth without additional procedures.
TaoyuanAges 20–70 - NCT06587880RecruitingPhase 4
Mouthwash and wisdom tooth extraction recovery
This study compares different mouthwashes to see which one helps healing after wisdom tooth surgery. If you have a lower wisdom tooth that is impacted (stuck) and need it removed with some bone cutting, you may qualify.
AmmanAges 18 years+ - NCT07723404Recruiting
Comparing two ways to scan dental implants for a new bridge
This trial compares two techniques for scanning dental implants in the upper jaw to make a new permanent bridge or denture. It aims to find which method gives a more accurate fit.
Shibīn al Kawm, Shibin AlkomAges 20–60 - NCT07324525Recruiting
Oral health study for people in palliative care
This survey study explores oral health in people receiving palliative care. By answering a questionnaire, you can help improve care and comfort for patients with serious illness.
Göttingen, GermanyAges 18 years+ - NCT07185191Recruiting
Device to treat gum shrinkage and black triangles between teeth
This trial tests a medical device (RDM36) to see if it safely and effectively treats gum shrinkage and black triangles between the front teeth, which can affect your smile.
Brescia, ItalyAges 18 years+ - NCT07249242Recruiting
Gum healing around different healing caps on implants
This study compares how well gum tissue heals around different types of healing caps placed on dental implants. It may help you if you have a recently placed implant that meets certain space and strength requirements.
Boston, MassachusettsAges 18 years+ - NCT07104656Recruiting
Study of a new saw for jaw surgery
This trial tests a new way to cut the jawbone during surgery to see if it helps the bone pieces fit together better. It might help patients needing jaw surgery.
Birmingham, AlabamaAges 12–75 - NCT07722390Recruiting
Injection treatment for deep gum pockets
This study tests whether injecting a special substance made from your own blood can help treat deep gum pockets without surgery. It may be an option for people with advanced gum disease who have already had initial cleaning.
CairoAges Any age
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.