Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,544
- Phase 2144
- Phase 384
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Head and Neck Cancer35
- Gingivitis34
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT06732609Recruiting
Skin study using advanced imaging
This trial uses a special camera to study the skin around the mouth in healthy young adults. It aims to understand normal skin features.
RomaAges 20–35 - NCT07566676Recruiting
Faster Upper Front Tooth Movement With Micro-holes
This study tests a new way to move upper front teeth into better position using braces combined with tiny holes made in the bone. The goal is to correct an overbite (when upper front teeth stick out too far) more quickly and effectively.
Cairo, Nasr CityAges 15–25 - NCT07568249Recruiting
How full arch dental implants affect your quality of life
This study looks at how getting a full set of dental implants (for a whole upper or lower jaw) affects your oral health and quality of life. Researchers want to see how your experience changes from before treatment through recovery.
Lisbon, Lisbon DistrictAges 18 years+ - NCT07562334Recruiting
Cheekbone Implants With Two Tissue Coverage Methods
This trial compares two ways to cover and support cheekbone implants (zygomatic implants) in patients with severe upper jaw bone loss. The study tests whether a natural fat pad from your cheek or a special fibrin product (made from your own blood) works better to protect the implant and keep soft tissue thickness stable.
Cairo, Cairo GovernorateAges Any age - NCT07566936Enrolling by invitation
Digital vs. Traditional Splints for Jaw Joint Disorders
This study compares two types of custom-made jaw splints—one designed using digital technology and one made the traditional way—to see which better relieves jaw pain and improves mouth opening in people with temporomandibular disorder (TMD), a common condition affecting the jaw joint.
Islamabad, IslamabadAges 18–40 - NCT07560514Recruiting
Testing New Digital Tools to Detect Tooth Decay
This study tests new digital technologies—including a special camera called DIAGNOcam and AI software—to detect tooth decay early and accurately. If you have some cavities and healthy teeth in specific areas of your mouth, you may be eligible to help researchers improve how dentists find and diagnose tooth decay.
Martin, Žilina RegionAges 18–65 - NCT07567105Recruiting
Long-term stability of open-bite orthodontic treatment
This study looks at whether orthodontic treatment for anterior open bite (a gap between upper and lower front teeth when biting down) stays stable over time. The researchers want to understand what helps the correction last.
VantaaAges Any age - NCT07565753RecruitingEarly Phase 1
Testing a medication to stop bleeding after tonsil removal
This study tests a medicine called tranexamic acid to help stop bleeding in children who had their tonsils removed and are now bleeding more than a day after surgery. Researchers want to see if this medicine can reduce the amount of bleeding and help children recover faster.
Davis, CaliforniaAges 2–17 - NCT06717230Recruiting
Comparing ways to restore a back tooth after root canal
This study tests three different methods (digital, conventional, and biomimetic) to restore a back tooth that had a root canal and needs a crown-like covering. It aims to find which approach works best over one year.
El-Sheikh Zayed City, Giza GovernorateAges 15 years+ - NCT07557277Recruiting
Gum Recession and Quality of Life Study
This study looks at how gum recession (when gums pull back from teeth) affects your quality of life and oral health. Researchers will ask you questions and examine your teeth to understand this connection better.
Rohtak, HaryanaAges 18–45 - NCT07557875Recruiting
Laser Treatment for Tongue-Tie in Young Children
This study tests whether a special laser can safely and effectively treat tongue-tie (a condition where the tissue under the tongue is too tight) in children ages 3–6. The goal is to see if the laser helps the tongue move better and heals faster than other methods.
Ho Chi Minh CityAges 3–6 - NCT07555366Recruiting
Healing after tooth extraction: two treatment approaches
This study compares two treatments applied to the socket (the hole left after a tooth is removed) to help it heal better. One treatment uses a product called microRepair, and the other uses chlorhexidine, a common antimicrobial rinse. The goal is to see which helps the extraction site heal faster and with fewer problems.
Roma, RMAges 18–75 - NCT07552441Recruiting
Mouth Muscle Pressure and Upper Jaw Width Study
This study examines how the muscles around your mouth affect the width of your upper jaw. Researchers will measure the pressure your mouth muscles create to better understand jaw development and may help improve orthodontic treatment in the future.
Van, VanAges 12–25 - NCT07555223Recruiting
Using 3D Scans to Better Detect Tooth Decay
This study tests whether special 3D imaging and intraoral scanning tools can help dentists better identify tooth decay and plaque buildup. Researchers want to see if these new methods work well and could improve how cavities are diagnosed.
Wondelgem, BotestraatAges 18–70 - NCT07556211Enrolling by invitation
How Jaw Clenching Affects Athlete Performance
This study looks at whether jaw clenching during sleep or stress affects muscle strength and performance in swimmers and handball players. Researchers want to understand if treating jaw clenching might help athletes perform better.
LiègeAges 18–35 - NCT07552051Recruiting
Testing Bite Mark Analysis Using 3D Dental Scans
This study tests how accurately dentists can analyze bite marks using digital 3D models of teeth. Researchers will scan your upper teeth and use computer software to see if the same bite-mark patterns are found consistently—helping improve how bite marks are used in dental and legal cases.
Nantes, NantesAges 18 years+ - NCT07557459Recruiting
Checking the health of dental implants
This study looks at how dental implants (artificial tooth roots) are doing, especially around the gum and bone, to help keep them healthy. If you have implants that have been in place for at least 3 years, you may be able to join and get a thorough check-up.
A Coruña, A CoruñaAges Any age - NCT06742580Recruiting
Sudden facial paralysis and homocysteine study
This study looks at a possible link between a substance in the blood called homocysteine and sudden facial paralysis (Bell's palsy). If you've recently been diagnosed with this condition, you may be able to join.
AfyonkarahisarAges 18–80 - NCT06288477Recruiting
Comparing two treatments for baby molar teeth with deep decay
This study compares two treatments for baby molar teeth that have deep decay but are still healthy otherwise: a newer material called Neo-putty (a type of bioceramic material) versus a standard medicine called formocresol. The goal is to see which one works better to keep the tooth healthy and prevent further problems.
El-Sheikh Zayed City, Giza GovernorateAges 4–9 - NCT07544394Recruiting
Understanding Fatigue in Sjögren's Syndrome
This study explores why people with Sjögren's syndrome experience fatigue and what factors predict it. Researchers will follow you for 3 months to better understand your fatigue patterns and potentially improve treatment.
KahramanmaraşAges 18 years+ - NCT07550127Recruiting
Comparing surgery and aftercare for infected dental implants
This study tests two ways of managing an infection around dental implants (called peri-implantitis) that is severe enough to need surgery. It compares surgery alone to surgery plus a special maintenance cleaning to see which gives better long-term results. If you are eligible, you would receive treatment for the infection and be followed for 3 months.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07548398Recruiting
Gummy Smile Study: Gum and Tooth Position Research
This study looks at why some people show a lot of gum when they smile and how their teeth erupt (come in). Researchers want to understand how common these conditions are and what factors influence them.
Roma, RMAges 18–50 - NCT07548502Recruiting
Night Guard Effect on Jaw Muscle Size in Children With Teeth Grinding
This study looks at whether wearing a night guard (a protective dental device) can help reduce jaw muscle thickness in children who grind their teeth at night. Researchers will measure changes in the masseter muscle, which is the main chewing muscle in your jaw.
NiğdeAges 10–12 - NCT07550725Recruiting
Full Arch Dental Implant Impressions Study
This study tests different techniques for taking accurate impressions (molds) of your upper jaw when preparing for full-arch dental implants (a fixed bridge supported by implants). The goal is to improve the fit and success of your final implant-supported teeth.
GizaAges 55–65
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,741 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.