Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT07679451Recruiting
Comparing two membranes for jawbone grafting before dental implants
This trial compares two types of membranes (PEEK vs PTFE) used in a bone-grafting procedure to rebuild the upper jawbone where teeth are missing. It may be an option for you if you need extra bone before getting dental implants.
Al Mansurah, DakhaliyaAges 20–45 - NCT06776640Recruiting
Vitamin D3 before dental implant surgery for better bone bonding
This trial tests whether taking vitamin D3 pills before and after dental implant surgery helps the implant bond better with the bone. It is for people who have low vitamin D levels and are already scheduled for an implant.
Nantes, NantesAges 18 years+ - NCT07377240Recruiting
Understanding barriers to changing eating habits in families with severe tooth decay in young children
This study talks to parents of young children (under 6) with severe early childhood cavities to understand what makes it hard to change risky eating habits. The goal is to help dentists support families better.
Clermont-FerrandAges Any age - NCT05715359Enrolling by invitation
Osteotomy guide for jaw reconstruction in prior patients
This study looks at the results of using a standardized “cutting guide” during jaw reconstruction surgery. If you had this kind of jaw reconstruction at the hospital and can be followed for at least a year, your past care may be included to evaluate how well the method works.
LundAges 20 years+ - NCT06757686Recruiting
Treating front open bite with bone-anchored appliance
This study tests a new way to fix a front open bite in adults. It uses a special appliance anchored to bone or screws in the upper jaw to gently push the back teeth upward, which helps close the open bite. If you have an open bite of 3 to 8 mm and need this type of orthodontic treatment, this could be an option.
Al MansurahAges 15–27 - NCT06732609Recruiting
Skin study using advanced imaging
This trial uses a special camera to study the skin around the mouth in healthy young adults. It aims to understand normal skin features.
RomaAges 20–35 - NCT07290725Enrolling by invitation
Translating a dental tool for special needs patients
This study is testing a translation of a tool used by dentists for patients with special needs. Dentists who speak German, Spanish, or Portuguese as their first language will fill out the form twice to help make sure it works well in their language.
Vienna, State of ViennaAges Any age - NCT07622277Recruiting
Teeth Alignment Stability After Braces: A Retention Study
This study compares how different face types maintain their bite after orthodontic braces are removed. Researchers will use 3D imaging to track whether teeth stay in their corrected positions during the retention phase (when you wear retainers).
Rohtak, HaryanaAges 18–45 - NCT06728696Enrolling by invitation
Comparing two gum healing methods after tooth implant
This study tests two ways to help the gum heal around a dental implant placed right after a tooth is pulled. It compares using a small piece of gum tissue from the mouth versus a special growth factor concentrate to see which one gives better gum shape and health.
Cairo, Cairo GovernorateAges 20–50 - NCT06720168Recruiting
Erythritol air polisher for dental black stain treatment
This trial tests if a special cleaning tool using erythritol can safely remove black stains from teeth caused by bacteria. It may help people with at least two stained teeth who haven't used antibiotics recently or have certain health issues.
Alfara del Patriarca, ValenciaAges Any age - NCT06714747Recruiting
Soft tissue prediction for jaw surgery
This trial tests a new way to predict how facial soft tissues will change after jaw surgery using advanced imaging. It may help people needing orthognathic surgery to understand the likely aesthetic outcome.
Bologna, Emilia-RomagnaAges 18 years+ - NCT06715722Recruiting
Comparing implant connector designs for 3-tooth bridges
This study compares two types of connector designs for dental implants that support a 3-tooth bridge in the lower jaw. It may help you understand which design gives better stability and comfort.
AmmanAges 18 years+ - NCT06714695Recruiting
Testing a mouthwash for black stains on kids' teeth
This trial tests if a special mouthwash made from chitosan (a natural substance from shellfish) can prevent black stains from coming back on children's teeth. Kids will use the mouthwash and be checked over 18 weeks to see if it works.
Cairo, Cairo GovernorateAges 6–12 - NCT06711081Recruiting
Laser and cold therapy for painful back tooth
This study tests whether using a low-level laser and cold therapy together helps heal a back tooth that has deep decay and is causing severe pain. The goal is to save the tooth and avoid a root canal.
TantaAges 15–60 - NCT06708481RecruitingEarly Phase 1
Resin vs peptide gel for white spots on teeth in children
This study compares two treatments for white spots on teeth: a resin (tooth-colored coating) and a special peptide gel that helps rebuild enamel. It is for children and young teens with early white spots that haven't been treated yet.
Cairo, Giza GovernorateAges 7–14 - NCT07617480Enrolling by invitation
Orthodontic bracket bonding: acid etching with or without sandblasting
This study compares two methods of preparing tooth surfaces before attaching orthodontic brackets (the small squares glued to teeth during braces treatment). Researchers want to see which method—using acid alone or acid plus sandblasting—keeps brackets bonded better to your teeth.
DhakaAges 18–64 - NCT06700772RecruitingPhase 1
Bone Growth After Sinus Lift for Missing Upper Teeth
This study tests a surgery to build up bone in the upper jaw where teeth are missing. It may help people who need more bone to get dental implants later.
Cairo, New CairoAges 20–50 - NCT06681844Recruiting
Predicting tooth wear from knocked-out teeth
This study will look at teeth that have been knocked out to find out if the amount of wear on the tooth can help predict how much more wear might happen. If you have a tooth like this, it might help researchers understand tooth wear better.
Indianapolis, IndianaAges 18–80 - NCT06676098Recruiting
Best spot for a guided numbing shot for root canals
This study compares different injection spots for a new device that helps numb lower back teeth before root canal treatment. If you need a root canal on a lower molar or premolar, you may be able to help find the best spot for the numbing shot.
Boston, MassachusettsAges 18 years+ - NCT06673576Recruiting
Comparing 3D scanning methods to measure gum changes after crown lengthening
This study tests a new 3D scanning technique to measure gum changes after crown lengthening surgery. It aims to see if the new method is as accurate as the current standard approach.
CairoAges 18 years+ - NCT07359339Recruiting
Microneedling with or without platelet-rich plasma for gum dark spots
This trial tests whether a treatment called microneedling (tiny needles that stimulate the skin) combined with a special healing liquid from your own blood (platelet-rich plasma) works better than microneedling alone for removing dark spots on the gums.
Cairo, El ManialAges 18 years+ - NCT06797778Enrolling by invitation
Oral health program for schoolchildren
This trial is a program to teach kids in Polígono Sur schools how to take care of their teeth and gums. It's a simple, no-risk way to learn about oral health.
Seville, SevillaAges Any age - NCT06634017RecruitingPhase 1/Phase 2
Platelet-rich fibrin gel to speed up tooth movement with braces
This study tests whether a special gel made from your own blood (platelet-rich fibrin) can speed up tooth movement after a premolar extraction. You would be wearing braces, and one side of your mouth gets the gel while the other side is the control, so we can see if it works.
Karachi, SindhAges 18–45 - NCT06633822Recruiting
Crown Lengthening with Digital Planning for a Better Smile
This trial tests a new digital planning method for crown lengthening (a procedure to reshape gum tissue around a tooth to improve smile appearance). It might help you if you have a front tooth needing cosmetic gum work and have healthy gums and good oral hygiene.
Madrid, MadridAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.